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Total 30 results found since Jan 2013.

The continuous performance test aids the diagnosis of post-stroke cognitive impairment in patients with right hemisphere damage
ConclusionThe CPT may be helpful in the clinical diagnosis of PSCI with RHD. It may therefore be used to evaluate the effectiveness of cognitive interventions.
Source: Frontiers in Neurology - June 28, 2023 Category: Neurology Source Type: research

ASPECT Score and Its Application to Vasospasm in Aneurysmal Subarachnoid Haemorrhage: a Case –Control Study
AbstractDelayed cerebral ischaemia (DCI) is a significant complication of aneurysmal subarachnoid haemorrhage (aSAH) and is strongly associated with poorer outcome. The Alberta Stroke Program Early Computer Tomography (ASPECT) score is an established scoring tool, used in acute ischaemic stroke, to quantify early ischaemic changes on CT head scans. We aim to identify if ASPECT scoring correlates with functional outcome in DCI following aSAH. Retrospective case –control study. Inclusion criteria: admission to the Department of Neurosurgery at Leeds Teaching Hospitals NHS Trust (a tertiary neurosurgical centre in the Unite...
Source: Translational Stroke Research - August 9, 2022 Category: Neurology Source Type: research

Can Mindfulness-Based Interventions Benefit People with Dementia? Drawing on The Evidence from a Systematic Review in Populations with Cognitive Impairments.
Authors: Chan J, Leung DKY, Walton H, Wong GHY, Spector A Abstract INTRODUCTION: Non-pharmacological interventions that promote quality of life in people with dementia are urgently needed. To accelerate development, evidence-based psychotherapies used in other populations can be considered. Mindfulness-based interventions with standardised protocols, namely mindfulness-based cognitive therapy (MBCT) and mindfulness-based stress reduction (MBSR), may be effective in people with dementia, although tailoring for cognitive impairment may be needed. Evidence from other cognitive disorders can inform research. AREAS COVE...
Source: Expert Review of Neurotherapeutics - August 28, 2020 Category: Neurology Tags: Expert Rev Neurother Source Type: research

Endothelial Progenitor Cells Induce Angiogenesis: a Potential Mechanism Underlying Neovascularization in Encephaloduroarteriosynangiosis
AbstractEncephaloduroarteriosynangiosis (EDAS) is one of the most commonly used indirect vascular reconstruction methods. EDAS aids in the formation of collateral vessels from the extracranial to the intracranial circulation in patients with moyamoya disease (MMD). However, the underlying mechanism of collateral vessel formation is not well understood. Endothelial progenitor cells (EPCs) differentiate to form the vascular endothelial cells and play a very important role in angiogenesis. We designed this prospective clinical trial to investigate the presence of EPCs in patients with MMD and to explore the neovascularization...
Source: Translational Stroke Research - July 5, 2020 Category: Neurology Source Type: research

Physical therapists' perspectives on improving walking capacity in patients with stroke: a cross-sectional study from Saudi Arabia.
CONCLUSION: Variable responses from different sectors according to qualification, experience, and institution were observed among the physical therapists in Saudi Arabia for improving the walking capacity in patients after Stroke. PMID: 32481238 [PubMed - in process]
Source: Journal of Musculoskeletal Neuronal Interactions - June 4, 2020 Category: Neurology Tags: J Musculoskelet Neuronal Interact Source Type: research

Detailed phenotyping of posterior vs. anterior circulation ischemic stroke: a multi-center MRI study
ConclusionIschemic stroke subtypes differ between the two phenotypes. Diabetes and male sex have a stronger association with PCiS than ACiS. Definitive MRI-based PCiS diagnosis aids etiological investigation and contributes additional insights into specific risk factors and mechanisms of injury in PCiS.
Source: Journal of Neurology - November 10, 2019 Category: Neurology Source Type: research

Using Dental Pulp Stem Cells for Stroke Therapy
Conclusion and Future Perspectives Stem cell-based therapy is a promising alternative for stroke treatment. While stem cells from different sources, including induced PSC, ESC, MSC, and NSC, have been investigated, using NSC and enhancing the natural mechanisms is most appropriate for brain repair. In preclinical models of stroke, stem cell transplantation has led to positive outcomes through a variety of cellular and molecular mechanisms, many being mediated by the array of beneficial factors produced by the cells. Recent advances in cellular reprogramming have provided alternative sources of NSC to be investigated, allo...
Source: Frontiers in Neurology - April 28, 2019 Category: Neurology Source Type: research

Factors Mediating Outcome After Stroke: Gender, Thrombolysis, and Their Interaction
AbstractSeveral studies, but not all, have shown that women benefit more from intravenous thrombolysis than men; few have accounted for pre-stroke mobility. Our aim was to determine whether there was an interaction between gender and thrombolysis treatment in 3-month modified Rankin Scale (mRS) score, after adjusting for pre-stroke mobility. We retrospectively reviewed medical records of 1390 consecutive ischemic stroke patients admitted between October 2012 and July 2015. The 3-month mRS was obtained from clinic visits. Thrombolysis-by-gender interaction was evaluated in univariate and multivariate analyses using ordinal ...
Source: Translational Stroke Research - October 24, 2017 Category: Neurology Source Type: research

Fidelity to a motivational interviewing intervention for those with post-stroke aphasia: a small-scale feasibility study.
This study aimed to explore the feasibility of motivational interviewing (MI) in people with post-stroke aphasia. METHODS: In a small-scale feasibility study, consecutive patients admitted to an acute stroke ward were screened for eligibility. People with moderate to severe aphasia were eligible. Those consenting received an intervention consisting of up to eight MI sessions delivered twice per week over four weeks. Sessions were modified using aids and adaptations for aphasia. Session quality was measured using the Motivational Interviewing Skills Code (MISC) to assess MI fidelity. RESULTS: Three consenting pati...
Source: Topics in Stroke Rehabilitation - September 27, 2017 Category: Neurology Authors: Holland EJ, Watkins CL, Boaden E, Lightbody CE Tags: Top Stroke Rehabil Source Type: research

Incidence of Stroke in the US Centers for AIDS Research (CFAR) Network of Integrated Clinical Systems (CNICS) Cohort (S51.008)
Conclusions:In this large study of neurologist adjudicated stroke in a HIV cohort, the AS stroke incidence rate was 337.7. The stroke rate was higher in women, African-Americans and older ages. These incidence data, combined with additional risk factor analyses, and comparisons with non-HIV cohorts, will allow better understanding of stroke in HIV, with the ultimate goal of improved outcomes.Study Supported by: NIAID, NHLBI (5R24AI067039) and AHA (13GRNT14560022)Disclosure: Dr. Tirschwell has received research support from St. Jude Medical and Bayer. Dr. Chow has nothing to disclose. Dr. Becker has received personal compen...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Tirschwell, D., Chow, F., Becker, K., Marra, C., Zunt, J., Ho, E., Kalani, R., Huffer, A., Nance, R., Williams-Nguyen, J., Burkholder, G., Moore, R., Mathews, W., Eron, J., Drozd, D., Kitahata, M., Saag, M., Crane, H. Tags: Cerebrovascular Disease and Interventional Neurology: Stroke Prevention and Translation Source Type: research

Post-Stroke Disability at a National Referral Hospital in Tanzania (P3.322)
Conclusions:In this low-resource setting, individuals with stroke face a severe burden of disability and high risk of mortality. The majority of participants experienced severe deficits following stroke, as assessed through NIHSS and mRS. While this study may be limited by referral bias, the high toll of disability among this population suggests that post-stroke disability places a significant burden on Tanzanian families and society.Study Supported by:This abstract was made possible with help from the Harvard University Center for AIDS Research (CFAR), an NIH funded program (P30 AI060354), subgrant to F. Mateen.Disclosure...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Wibecan, L., Mmbando, T., Grundy, S., Klein, J., Mateen, F., Okengo, K. Tags: Global Health Source Type: research

Delivering Knowledge of Stroke to Parents Through Their Children Using a Manga for Stroke Education in Elementary School
This study aimed to clarify the effectiveness of our new educational aids that were developed for elementary school children to impart information about stroke to children and their parents in 2 different ways: with or without stroke lessons by a neurologist.
Source: Journal of Stroke and Cerebrovascular Diseases - November 8, 2016 Category: Neurology Authors: Akiko Ishigami, Chiaki Yokota, Kunihiro Nishimura, Satoshi Ohyama, Shinya Tomari, Tenyu Hino, Takuro Arimizu, Shinichi Wada, Kazunori Toyoda, Kazuo Minematsu Source Type: research

Factors influencing the response to  high-frequency repetitive transcranial magnetic stimulation in patients with subacute stroke.
CONCLUSION: Our findings suggest that high-frequency rTMS interventions aimed at improving upper extremity motor function in patients with subacute stroke with moderate to severe motor involvement should be individually tailored according to functional CST status and BDNF genotype. PMID: 27372515 [PubMed - as supplied by publisher]
Source: Restorative Neurology and Neuroscience - July 21, 2016 Category: Neurology Tags: Restor Neurol Neurosci Source Type: research

Factors influencing the response to high-frequency repetitive transcranial magnetic stimulation in patients with subacute stroke.
CONCLUSION: Our findings suggest that high-frequency rTMS interventions aimed at improving upper extremity motor function in patients with subacute stroke with moderate to severe motor involvement should be individually tailored according to functional CST status and BDNF genotype. PMID: 27372515 [PubMed - as supplied by publisher]
Source: Restorative Neurology and Neuroscience - July 5, 2016 Category: Neurology Tags: Restor Neurol Neurosci Source Type: research

First Automated Stroke Imaging Evaluation via Electronic Alberta Stroke Program Early CT Score in a Mobile Stroke Unit
Conclusions: This study on the integration of e-ASPECTS into the prehospital stroke management via a MSU showed for the first time that such integration is feasible, and aids both decision regarding the treatment option and the triage regarding the most appropriate target hospital.Cerebrovasc Dis 2016;42:332-338
Source: Cerebrovascular Diseases - June 15, 2016 Category: Neurology Source Type: research