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Treatment Delays and Chance of Reperfusion Therapy in Patients with Acute Stroke: A Danish Nationwide Study
Conclusions: Patient delay remains the most important barrier for use of reperfusion therapy among acute ischemic stroke patients calling 1-1-2, whereas system delay seems independent of patient delay.Cerebrovasc Dis
Source: Cerebrovascular Diseases - October 31, 2022 Category: Neurology Source Type: research

Risk of Major Cardiovascular and Cerebrovascular Events in Users of Lisdexamfetamine and Other Medications for Attention-Deficit/Hyperactivity Disorder in Denmark and Sweden: A Population-Based Cohort Study
ConclusionOur findings suggest little to no increased risk of cardiovascular and cerebrovascular events in patients treated with LDX compared with patients previously treated with other ADHD medications.
Source: Neurology and Therapy - October 23, 2022 Category: Neurology Source Type: research

Can Helicopters Solve the Transport Dilemma for Patients With Symptoms of Large-Vessel Occlusion Stroke in Intermediate Density Areas? A Simulation Model Based on Real Life Data
ConclusionsOur model calculations suggest that using helicopters to transport patients with stroke directly to the CSC in intermediate density areas markedly reduce onset-to-groin time without affecting time to thrombolysis. In this setting, helicopter capacity is not challenged by increasing the capture zone.
Source: Frontiers in Neurology - April 25, 2022 Category: Neurology Source Type: research

Sex differences in independence in activities of daily living early in stroke rehabilitation
ConclusionIn a homogeneous sample of stroke survivors undergoing specialized 24-h stroke rehabilitation for 11 –14 days, females were more dependent in ADL than males.
Source: Brain and Behavior - June 14, 2021 Category: Neurology Authors: Monique Mesot Liljehult, My Catarina Euler ‐Chelpin, Thomas Christensen, Lise Buus, Jannik Stokholm, Susanne Rosthøj Tags: ORIGINAL RESEARCH Source Type: research

Does General Anesthesia Compared With Conscious Sedation Result in Better Outcomes in Acute Stroke Patients Undergoing Endovascular Therapy?
Conclusions: GA does not result in worse tissue outcomes or worse clinical outcomes when compared with CS in acute stroke patients with large vessel occlusion undergoing mechanical thrombectomy.
Source: The Neurologist - March 1, 2021 Category: Neurology Tags: Critically Appraised Topics Source Type: research

Knowledge and application of upper limb prediction models and attitude toward prognosis among physiotherapists and occupational therapists in the clinical stroke setting.
CONCLUSIONS: Results from this study indicate that prediction models for UL function after stroke are not yet a part of daily practice in Danish stroke rehabilitation. At the same time, knowledge of prognosis seems to be relevant for most therapists in their clinical work. PMID: 32583731 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - June 24, 2020 Category: Neurology Authors: Kiær C, Lundquist CB, Brunner I Tags: Top Stroke Rehabil Source Type: research

Elevated miR-9 in Cerebrospinal Fluid Is Associated with Poor Functional Outcome After Subarachnoid Hemorrhage
This study evaluated microRNA (miRNA) changes in cerebrospinal fluid (CSF) and their association with the occurrence of delayed cerebral ischemia (DCI) and poor functional outcome after SAH. Forty-three selected miRNAs were measured in daily CSF samples from a discovery cohort of SAH patients admitted to Rigshospitalet, Copenhagen, Denmark, and compared with neurologically healthy patients. Findings were validated in CSF from a replication cohort of SAH patients admitted to Massachusetts General Hospital, Boston, Massachusetts. The CSF levels of miRNA over time were compared with the occurrence of DCI, and functional outco...
Source: Translational Stroke Research - April 3, 2020 Category: Neurology Source Type: research

A support programme for secondary prevention in patients with transient ischaemic attack and minor stroke (INSPiRE-TMS): an open-label, randomised controlled trial
Publication date: Available online 7 November 2019Source: The Lancet NeurologyAuthor(s): Michael Ahmadi, Inga Laumeier, Thomas Ihl, Maureen Steinicke, Caroline Ferse, Matthias Endres, Armin Grau, Sidsel Hastrup, Holger Poppert, Frederick Palm, Martin Schoene, Christian L Seifert, Farid I Kandil, Joachim E Weber, Paul von Weitzel-Mudersbach, Martin L J Wimmer, Ale Algra, Pierre Amarenco, Jacoba P Greving, Otto BusseSummaryBackgroundPatients with recent stroke or transient ischaemic attack are at high risk for a further vascular event, possibly leading to permanent disability or death. Although evidence-based treatments for ...
Source: The Lancet Neurology - November 8, 2019 Category: Neurology Source Type: research

Performance Stability and Interrater Reliability of Culturally Adapted 10-Meter Walking Test for Danes with Neurological Disorders
Background: The 10-meter Walking Test (10MWT) is often used to assess people with, e.g., stroke, but often using different procedures. The aims of this study were to translate the 10MWT into Danish, to determine the number of trials needed to achieve performance stability, and to examine the interrater reliability and agreement of the 10MWT in people with neurological disorders. Methods: Translation followed international recommendations, and evaluated in a consecutive sample of 50 people with a neurological disorder.
Source: Journal of Stroke and Cerebrovascular Diseases - July 3, 2019 Category: Neurology Authors: Christina Weirum Andersen, Morten Tange Kristensen Source Type: research

Acupuncture for Post-stroke Shoulder-Hand Syndrome: A Systematic Review and Meta-Analysis
Conclusions: Acupuncture therapy seems effective for motor function, pain relief and activities of daily living in stroke patients with mild SHS, when it is used in combination with rehabilitation. The low certainty of evidence downgrades our confidence in making recommendations to clinical practice. Introduction Shoulder-hand syndrome (SHS) is a common condition among people who have had a stroke, with its reported prevalence ranging from 12% to 49% (1, 2). The main symptoms of SHS include pain, hyperalgesia, joint swelling and limitations in range of motion (ROM) (3). Post-stroke SHS is also named type I complex ...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

Corticospinal Tract Integrity and Long-Term Hand Function Prognosis in Patients With Stroke
Conclusions: The present study showed that CST integrity (at 6 months after onset) in patients with chronic stroke was related to functional hand status. In addition, the mid-pons FA value was more predictive of functional restoration of the hand than the FN or FA value at the pontomedullary junction. These results may be useful in predicting the functional restoration of the hand and understanding the functional prognosis of stroke. Introduction Restoration of hand function is one of the most important goals for patients with stroke (1). Thus, techniques that aid in predicting restoration of hand function are also i...
Source: Frontiers in Neurology - April 14, 2019 Category: Neurology Source Type: research

Social Inequality by Income in Short- and Long-Term Cause-Specific Mortality after Stroke
Goals: It is unclear whether social inequality exists for mortality after stroke. Results of studies on the relation between socioeconomic position (SEP) and mortality after stroke have been inconsistent and inconclusive. Material and Methods: We studied the association between SEP expressed by income and the risk of death after stroke by merging data on incident stroke from Danish registries with nationwide coverage. We identified all incident cases of stroke hospitalized in Denmark 2003-2012 (n  = 60503).
Source: Journal of Stroke and Cerebrovascular Diseases - March 27, 2019 Category: Neurology Authors: Klaus Kaae Andersen, Tom Skyh øj Olsen Source Type: research

Post-stroke lower urinary system dysfunction and its relation with functional and mental status: a multicenter cross-sectional study.
CONCLUSION: LUTD is a common problem in patients with stroke. LUTD is associated with poorer cognitive and functional status and the quality of life in these patients. We, therefore, suggest that bladder dysfunction should not be overlooked during rehabilitation of stroke patients. PMID: 30570391 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - December 20, 2018 Category: Neurology Authors: Akkoç Y, Bardak AN, Ersöz M, Yılmaz B, Yıldız N, Erhan B, Tunç H, Koklu K, Alemdaroğlu E, Dogan A, Ozisler Z, Koyuncu E, Şimşir Atalay N, Gündüz B, Işık R, Güler A, Sekizkardeş M, Demir Y, Yaşar E, Sasmaz E, Şatır Ö Tags: Top Stroke Rehabil Source Type: research

Guillain –Barré syndrome in Denmark: a population-based study on epidemiology, diagnosis and clinical severity
ConclusionThe epidemiology and full clinical spectrum of GBS are described in a population-based study. This includes a larger proportion of milder cases that are underrepresented in prospective cohorts such as IGOS.
Source: Journal of Neurology - December 7, 2018 Category: Neurology Source Type: research

Age as a prognostic factor in relation to surgical evacuation of spontaneous supratentorial intracerebral haemorrhage.
CONCLUSIONS AND CLINICAL IMPLICATIONS: Neurosurgical treatment of the sICH patients is indicated only if age and potentially improved morbidity is carefully evaluated considering the STICH and this study; otherwise, we will just increase the health care burden with a number of extremely care-dependent patients. PMID: 30279050 [PubMed - as supplied by publisher]
Source: Neurologia i Neurochirurgia Polska - September 24, 2018 Category: Neurology Authors: Zaer H, Ketharanathan B, Carlsen JG, Shahbazi S, Sørensen JCH Tags: Neurol Neurochir Pol Source Type: research

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