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Intracranial Hemorrhage as a Marker for Mycotic Aneurysm in Patients With Infective Endocarditis
Discussion Patients with left-sided and right-sided endocarditis with PFO and ICH on CNS imaging were more likely to have mycotic aneurysms detected through DSA than similar patients without ICH. Routine DSA screening for mycotic aneurysms may not be required in patients with endocarditis undergoing evaluation for valve surgery who present without ICH on CNS imaging.
Source: Neurology Clinical Practice - March 10, 2023 Category: Neurology Authors: Williams, T. J., Starr, M., El-Dalati, S. Tags: CT, MRI, Bacterial infections, Embolism, Intracerebral hemorrhage Research Article Source Type: research

Peripheral eosinophil trends and clinical outcomes after non-traumatic subarachnoid hemorrhage
ConclusionThis study demonstrated that a delayed increase in eosinophils after SAH occurs and may contribute to functional outcomes. The mechanism of this effect and the relationship with SAH pathophysiology merit further investigation.
Source: Frontiers in Neurology - February 21, 2023 Category: Neurology Source Type: research

Relevance of admission hyperglycaemia and diabetes mellitus to efficacy and safety of mechanical thrombectomy in stroke patients
CONCLUSIONS: Diabetes mellitus has a neutral effect on the angiographic and clinical outcomes of mechanical thrombectomy in stroke patients. It does not increase the risk of intracranial haemorrhage after instrumental therapy. It is admission hyperglycaemia, rather than diabetes mellitus, that is a predictor of poor functional status in patients treated with thrombectomy. According to our results, the patient's neurological status, age, and the outcome of thrombectomy are relevant to the functional status in the acute ischaemic stroke period.PMID:36394219 | DOI:10.5603/PJNNS.a2022.0063
Source: Neurologia i Neurochirurgia Polska - November 17, 2022 Category: Neurology Authors: Anetta Lasek-Bal Amadeusz Żak Łukasz Binek Sebastian Student Aleksandra Cie ślik Wies ław Bal Wiktor Rybicki Jolanta Kulawik-Szwajca Source Type: research

Association Between Carotid Artery Perivascular Fat Density and Embolic Stroke of Undetermined Source
ConclusionWe found increased density in the fat surrounding carotid artery ipsilateral to stroke compared with contralateral in ESUS, suggesting the presence of an inflammatory reaction that extends beyond the vessel lumen in patients with ESUS with a risk factor profile similar to LAA strokes.
Source: Frontiers in Neurology - February 18, 2022 Category: Neurology Source Type: research

Hemodynamic Differences Between Basilar Artery Fenestration and Normal Vertebrobasilar Artery: A Pilot Study
Conclusions: This pilot study suggested that hemodynamic differences between BAF and normal vertebrobasilar artery across multiple shear flow parameters. The disturbed flow in the BAF may increase the risk of thrombus formation, plaque instability, and subsequent ischemic cerebrovascular events. These should be confirmed by future studies.
Source: Frontiers in Neurology - January 13, 2022 Category: Neurology Source Type: research

Status epilepticus mimicking stroke recurrence
This article is part of the Special Issue “Seizures & Stroke”
Source: Epilepsy and Behavior - October 17, 2019 Category: Neurology Source Type: research

Status epilepticus mimicking stroke recurrence.
CONCLUSION: Status epilepticus is not infrequent in patients with previous stroke and may present with negative neurological symptoms, thus mimicking a stroke recurrence. EEG should be considered as a potential diagnostic tool in the acute stroke setting, at least in patients with previous stroke. This article is part of the Special Issue "Seizures & Stroke". PMID: 31629647 [PubMed - as supplied by publisher]
Source: Epilepsy and Behaviour - October 15, 2019 Category: Neurology Authors: Pauletto G, Bax F, Gigli GL, Lorenzut S, Verriello L, Corazza E, Valente M Tags: Epilepsy Behav Source Type: research

Hemodynamic Characteristics Associated With Paraclinoid Aneurysm Recurrence in Patients After Embolization
Conclusions: High peak systolic WSS, OSI and velocity around aneurysm neck areas after embolization of paraclinoidal aneurysms may be important factors leading to recurrence. Introduction Paraclinoid aneurysms are defined as aneurysms arising from the segment of the internal carotid artery (ICA) between the distal dural ring and the origin of the posterior communicating artery. They account for approximately 1.3–5% of all intracranial aneurysms and they comprise the majority of such aneurysms in females (1–3). Hemodynamic characteristics are thought to be the most important risk factors for occurrence...
Source: Frontiers in Neurology - April 24, 2019 Category: Neurology Source Type: research

Stroke Dysbiosis Index (SDI) in Gut Microbiome Are Associated With Brain Injury and Prognosis of Stroke
Conclusions: We developed an index to measure gut microbiota dysbiosis in stroke patients; this index was significantly correlated with patients' outcome and was causally related to outcome in a mouse model of stroke. Our model facilitates the potential clinical application of gut microbiota data in stroke and adds quantitative evidence linking the gut microbiota to stroke. Introduction Ischemic stroke imposes a heavy burden on society, with 24.9 million cases worldwide (1). Although intravenous thrombolysis and endovascular treatment greatly improve some patients' prognosis, the prognosis for most pa...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Utility of digital subtraction angiography ‐based collateral evaluation in medically treated acute symptomatic basilar artery stenosis
ConclusionsThe DSA‐based collateral scoring of the BA large branches might predict long‐term outcome in medically treated symptomatic basilar artery stenosis with mild initial severity. Evaluation of BA collateral perfusion status might be useful to determine appropriate treatment strategies.
Source: European Journal of Neurology - July 14, 2017 Category: Neurology Authors: W. ‐J. Lee, K.‐H. Jung, Y. J. Ryu, J.‐M. Kim, S.‐T. Lee, K. Chu, M. Kim, S. K. Lee, J.‐K. Roh Tags: Original Article Source Type: research

Arterial Tortuosity: An Imaging Biomarker of Childhood Stroke Pathogenesis? Clinical Sciences
Conclusions— In children with dissection and transient cerebral arteriopathy, cerebral arteries demonstrate increased tortuosity. Quantified arterial tortuosity may represent a clinically relevant imaging biomarker of vascular biology in pediatric stroke.
Source: Stroke - April 24, 2016 Category: Neurology Authors: Wei, F., Diedrich, K. T., Fullerton, H. J., deVeber, G., Wintermark, M., Hodge, J., Kirton, A., the Vascular Effects of Infection in Pediatric Stroke (VIPS) Investigators, Dowling, Benedict, Bernard, Fox, Friedman, Lo, Ichord, Tan, Mackay, Hernandez, Hump Tags: Risk Factors, Angiography, Magnetic Resonance Imaging (MRI), Ischemic Stroke, Vascular Disease Clinical Sciences Source Type: research

Detection of Symptomatic Carotid Plaque Using Source Data from MR and CT Angiography: A Correlative Study
Background: Carotid plaque MRI has been a useful method to characterize vulnerable atherosclerotic plaque elements. Recent investigations have suggested that source images from CT angiography (CTA) and MR angiography (MRA) can identify the simple high-risk features of symptom-producing carotid artery plaque. We studied the correlation and relative diagnostic accuracies of CTA and MRA source images in detecting symptomatic carotid artery plaque. Methods: Subjects were eligible if they had carotid stenosis between 50 and 99% and had MRA and CTA exams performed within 10 days of one another. We measured the soft (non-calcifie...
Source: Cerebrovascular Diseases - February 16, 2015 Category: Neurology Source Type: research

Endovascular Stroke Therapy Results Improve over Time: The ‘Learning Curve' at a New Comprehensive Stoke Center
Conclusions: At a new community-based CSC, improved outcome occurred from year 1 to year 2, and trends towards decreased mortality, fewer complications, and improved revascularization were observed. Furthermore, the data shows that improvement in NIHSS score after EST is associated with decreased mortality following stroke in this setting, implying a net benefit.Cerebrovasc Dis Extra 2014;4:235-242
Source: Cerebrovascular Diseases Extra - January 13, 2015 Category: Neurology Source Type: research

Quantifying Cerebral Collaterals In Carotid Artery Dissection May Help Stratify Stroke Risk. (P3.110)
CONCLUSIONS: These uncontrolled data suggest that a quantified score of distal cerebral collaterals could help stratify stroke risk and help guide management in patients with carotid artery dissection. Further controlled, prospective study in a larger and more diverse sample is warranted.Study Supported by: AHA/ASA NCRP 13CRP14140001Disclosure: Dr. Southerland has received personal compensation in an editorial capacity for Neurology Podcast. Dr. Gaughen has received personal compensation for activities with Covidien Neurovascular, Microvention, and Stryker Neurovascular as a consultant. Dr. McMurry has nothing to disclose....
Source: Neurology - April 9, 2014 Category: Neurology Authors: Southerland, A., Gaughen, J., McMurry, T., Wintermark, M., Majersik, J., Worrall, B. Tags: Cerebrovascular Disease and Interventional Neurology: Large Vessel Nonatherosclerotic Arteriopathies Source Type: research