Stroke Dysbiosis Index (SDI) in Gut Microbiome Are Associated With Brain Injury and Prognosis of Stroke
Stroke Dysbiosis Index (SDI) in Gut Microbiome Are Associated With Brain Injury and Prognosis of Stroke Geng-Hong Xia1†, Chao You1,2†, Xu-Xuan Gao1, Xiu-Li Zeng1, Jia-Jia Zhu1, Kai-Yu Xu3, Chu-Hong Tan1, Ruo-Ting Xu1, Qi-Heng Wu1, Hong-Wei Zhou3, Yan He4*‡ and Jia Yin1*‡ 1Department of Neurology, Nanfang Hospital, Southern Medical University, Guangzhou, China 2Department of Neurology, The First People's Hospital of Zunyi, Zunyi, China 3State Key Laboratory of Organ Failure Research, Division of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, China 4Microbiome Medicine Center, Division of Laboratory Medicine, Zhujiang Hospital, Southern Medical University, Guangzhou, China Background: Significant dysbiosis occurs in the gut microbiome of stroke patients. Condensing these broad, complex changes into one index would greatly facilitate the clinical usage of gut microbiome data. Here, we formulated a gut microbiota index in patients with acute ischemic stroke based on their gut microbiota dysbiosis patterns and tested whether the index was correlated with brain injury and early outcome. Methods: A total of 104 patients with acute ischemic stroke and 90 healthy individuals were recruited, and their gut microbiotas were compared and to model a Stroke Dysbiosis Index (SDI), which representing stroke-associated dysbiosis patterns overall. Another 83 patients and 70 controls were recruited for validation. ...
Both cases are recent arrivals from Nigeria;UN agency ’s comments follow South Africa’s call to reverse flight bans;G7 health ministers to hold urgent meeting on Omicron variantAt least 13 of 61 cases on two flights into Netherlands are new variantOmicron ’s worst impact will be in nations with low vaccination ratesWhat do we know about the new ‘worst ever’ Covid variant?See all our coronavirus coverageChina could face more than 630,000 Covid-19 infections a dayif it dropped its zero-tolerance policies by lifting travel curbs, according to a study by Peking University mathematicians, Reuters r...
What I mean to ask is that, removing anything amazing such as the preverbial cancer cure, being a Navy SEAL, or being a nurse in a low income hospital first etc, do adcoms consider the level of accomplishment/participation or just that it was done? For example, with leadership activities do reviewers notice and take into account if you were, say, the president of an international org as opposed to president or VP of a campus club? Both are leadership, both impressive but I would say the... Read more
The most popular medication to treat high blood pressure is not as effective as this drug.
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Last week I described some of the reasons for using a case formulation approach when working through initial assessment information, and today I’m going to describe one approach for organising a formulation. This is the “4 P” formulation, and it’s one that’s often used in mental health (Bolton, 2014). In the 4 P model, there are four questions to ask yourself: Preconditions – Why is this person vulnerable to this problem?Precipitating factors – Why now? This can mean “why is this person having symptoms now?” or “why is this person presenting to this person ...
Digital breast tomosynthesis (DBT) has shown itself to be a valid, beneficia...Read more on AuntMinnie.comRelated Reading: DBT can help evaluate cases of focal breast pain DBT + synthesized 2D mammo detects more cancers Mammography, DBT safe for accidental exam during pregnancy DBT screening shows value in community practice settings Synthesized mammo plus DBT handles calcifications differently
HIGH cholesterol describes a build-up of a fatty substance in your blood. There are various causes of this problem, putting you at a higher risk of heart problems and stroke. They range from poor diet to not exercising enough. However, certain foods can be actually beneficial for your levels.
Conclusions: The 6-month TTR identified patients at higher risk of worse outcomes. The subsequent gain of TTR may contribute to better transplant outcomes.
This study assessed tacrolimus dosing and monitoring practices in heart transplant recipients and evaluated the predictive performance of a Bayesian forecasting software using a renal transplant–derived tacrolimus model to predict tacrolimus concentrations. Methods: A retrospective audit of heart transplant recipients (n = 87) treated with tacrolimus was performed. Relevant data were collected from the time of transplant to discharge. The concordance of tacrolimus dosing and monitoring according to hospital guidelines was assessed. The observed and software-predicted tacrolimus concentrations (n = 931) were co...
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