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Specialty: Lipidology

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Total 122 results found since Jan 2013.

LDL-C/HDL-C is associated with ischaemic stroke in patients with non-valvular atrial fibrillation: a case-control study
This study explored the relationships between the low −/high-density lipoprotein cholesterol ratio (LDL-C/HDL-C) and other clinical indicators and ischaemic stroke (IS) in patients with non-valvular atrial fibr...
Source: Lipids in Health and Disease - October 7, 2020 Category: Lipidology Authors: Xiao-Xue Zhang, Meng Wei, Lu-Xiang Shang, Yan-Mei Lu, Ling Zhang, Yao-Dong Li, Jiang-Hua Zhang, Qiang Xing, Zu Kela Tu-Erhong, Bao-Peng Tang and Xian-Hui Zhou Tags: Research Source Type: research

Epigenetics of paraoxonases
Purpose of review Studies have shown the three-member paraoxonase (PON) multigene family to be involved in the development of a large variety of diseases with an inflammatory component. Environmental factors such as lifestyle-related factors differ widely between populations and it is important to consider that their impacts may be exerted through the epigenetic mechanisms, which connect genes, the environment and disease development and are a potential therapeutic avenue. Recent findings In the review period, very little was published on epigenetics of PON2 or PON3, mostly on their diagnostic value in cancer by measu...
Source: Current Opinion in Lipidology - July 30, 2020 Category: Lipidology Tags: HYPERLIPIDEMIA AND CARDIOVASCULAR DISEASE: Edited by Paul N. Durrington Source Type: research

Association between carotid intima media thickness and small dense low-density lipoprotein cholesterol in acute ischaemic stroke
This study is trying to explore the association betwee...
Source: Lipids in Health and Disease - July 28, 2020 Category: Lipidology Authors: Peiyang Zhou, Yan Shen, Lingyun Wang, Zhihua Cao, Wenmin Feng, Jincheng Liu, Lijun Wang, Peng Meng, Jinbo Yang, Wang-Yang Xu and Ping Gao Tags: Research Source Type: research

Relationship between the non-HDLc-to-HDLc ratio and carotid plaques in a high stroke risk population: a cross-sectional study in China
This study...
Source: Lipids in Health and Disease - July 13, 2020 Category: Lipidology Authors: Yan Liu, Zhenwen Zhang, Binlan Xia, Liping Wang, Hengzhong Zhang, Yan Zhu, Chao Liu and Bin Song Tags: Research Source Type: research

Lipoprotein(a) Levels and Association with Myocardial Infarction and Stroke in a Nationally Representative Cross-Sectional US Cohort
Lipoprotein(a) (Lp(a)) has not been well-studied in a nationally representative US cohort.
Source: Journal of Clinical Lipidology - July 2, 2020 Category: Lipidology Authors: Eric J. Brandt, Arya Mani, Erica S. Spatz, Nihar Desai, Khurram Nasir Tags: Original Research Source Type: research

Case Report: Acute Stroke Due to Cerebrovascular Atherosclerosis in Chinese-american Woman with Extremely High Level of High Density Lipoprotein-cholesterol (HDL-C) and Coronary Artery Calcium Score Equal Zero
Nothing to disclose.
Source: Journal of Clinical Lipidology - June 30, 2020 Category: Lipidology Authors: Jan Gong, Daniel Soffer Tags: Lipid Management in Special Populations Source Type: research

Association of sleep duration with stroke, myocardial infarction, and tumors in a Chinese population with metabolic syndrome: a retrospective study
Previous studies have suggested that abnormal sleep duration is associated with increased risk of metabolic syndrome (MetS). However, evidence on the association of sleep duration with stroke, myocardial infar...
Source: Lipids in Health and Disease - June 27, 2020 Category: Lipidology Authors: Yingnan YE, Linxi ZHANG, Anping WANG, Yuxia Wang, Shiqing WANG, Guang NING and Yiming MU Tags: Research Source Type: research

Low-density Lipoprotein Cholesterol Levels Among Individuals Experiencing Statin-Associated Symptoms: Data from the REasons for Geographic And Racial Differences in Stroke (REGARDS) Study
Guidelines recommend adults who discontinue statin therapy due to statin-associated symptoms be re-initiated. Low-density lipoprotein cholesterol (LDL-C) levels achieved after statin re-initiation are unknown.
Source: Journal of Clinical Lipidology - June 16, 2020 Category: Lipidology Authors: Rikki M. Tanner, Lisandro D. Colantonio, Meredith L. Kilgore, Matthew T. Mefford, Dayl T. Chachappan, Katherine E. Mues, Monika M. Safford, Robert S. Rosenson, Paul Muntner Tags: Original Research Source Type: research

Cholesterol reducer and thrombolytic therapy in acute ischemic stroke patients
Specific clinical risk factors may contribute to improving or worsening neurological functions in acute ischemic stroke (AIS) patients pre-treated with a combined cholesterol reducer and recombinant tissue pla...
Source: Lipids in Health and Disease - May 6, 2020 Category: Lipidology Authors: Nicolas Poupore, Dan Strat, Tristan Mackey, Katherine Brown, Ashley Snell and Thomas I. Nathaniel Tags: Research Source Type: research

The LDL cholesterol in stroke limbo: how low can we go?
No abstract available
Source: Current Opinion in Lipidology - May 1, 2020 Category: Lipidology Tags: BIMONTHLY UPDATE: Edited by Alan Rees Source Type: research

A genetic variant in the promoter of lncRNA MALAT1 is related to susceptibility of ischemic stroke
Metastasis-associated lung adenocarcinoma transcript-1 (MALAT1) was aberrantly expressed in diverse diseases. Particularly in ischemic stroke (IS), the abnormal expression of MALAT1 played important roles includi...
Source: Lipids in Health and Disease - April 1, 2020 Category: Lipidology Authors: Yan Wang, Xi-Xi Gu, Hua-Tuo Huang, Chun-Hong Liu and Ye-Sheng Wei Tags: Research Source Type: research

Genes associated with inflammation may serve as biomarkers for the diagnosis of coronary artery disease and ischaemic stroke
The current research aimed to expound the genes and pathways that are involved in coronary artery disease (CAD) and ischaemic stroke (IS) and the related mechanisms.
Source: Lipids in Health and Disease - March 12, 2020 Category: Lipidology Authors: Peng-Fei Zheng, Fu-Jun Liao, Rui-Xing Yin, Lu-Zhu Chen, Hui Li, Rong-Jun Nie, Yong Wang and Pei-Juan Liao Tags: Research Source Type: research

Associations between GUCY1A3 genetic polymorphisms and large artery atherosclerotic stroke risk in Chinese Han population: a case-control study
Previous genome-wide association studies have found two single nucleotide polymorphisms (SNP) rs7692387 and rs1842896 located on or near the GUCY1A3 gene were associated with coronary artery disease (CAD). GUCY1A...
Source: Lipids in Health and Disease - December 28, 2019 Category: Lipidology Authors: Jian-li Li, Liu-yu Liu, Dong-dong Jiang, Yi-ying Jiang, Guo-qiu Zhou, Dong-can Mo and Man Luo Tags: Research Source Type: research

Response to: “Arrhythmia paradox in patients with familial hypercholesterolemia”
We read the letter by Mirzaee and Cameron with great interest. We recently assessed the prognostic impact of clinically diagnosed familial hypercholesterolemia (FH) on long-term adverse cardiovascular outcomes in patients undergoing percutaneous coronary intervention for chronic and acute coronary syndromes. In our cohort, patients with probable or definite FH according to the Dutch Lipid Clinic Network faced a significant, approximate 2-fold increased risk for subsequent atherothrombotic events (death, myocardial infarction, or stroke) during a 6-year period of follow-up compared with patients with possible or unlikely FH.
Source: Journal of Clinical Lipidology - December 23, 2019 Category: Lipidology Authors: Maximilian Tscharre, Kurt Huber Tags: Letter to Editor Source Type: research

Cytochrome P450 derived epoxidized fatty acids as a therapeutic tool against neuroinflammatory diseases
Publication date: April 2020Source: Prostaglandins & Other Lipid Mediators, Volume 147Author(s): Jogen Atone, Karen Wagner, Kenji Hashimoto, Bruce D. HammockAbstractCytochrome P450 (CYP) metabolism of arachidonic acid (ARA) produces epoxy fatty acids (EpFAs) such as epoxyeicosatrienoic acids (EETs) that are known to exert protective effects in inflammatory disorders. Endogenous EpFAs are further metabolized into corresponding diols by the soluble epoxide hydrolase (sEH). Through inhibition of sEH, many studies have demonstrated the cardioprotective and renoprotective effects of EpFAs; however, the role of sEH inhibition in...
Source: Prostaglandins and Other Lipid Mediators - December 6, 2019 Category: Lipidology Source Type: research