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Specialty: Lipidology

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Total 122 results found since Jan 2013.

Association between lipoprotein(a) and thromboembolism in patients with non-valvular atrial fibrillation: a cross-sectional study
Lipoprotein(a) [Lp(a)] is a recognized risk factor for ischemic stroke (IS); however, its role in thromboembolism in patients with non-valvular atrial fibrillation (NVAF) remains controversial. We aimed to ass...
Source: Lipids in Health and Disease - August 25, 2022 Category: Lipidology Authors: Jie Song, Xiaoxue Zhang, Meng Wei, Yakun Bo, Xianhui Zhou and Baopeng Tang Tags: Research Source Type: research

Association between four nontraditional lipids and ischemic stroke: a cohort study in Shanghai, China
This study aimed to examine the association of four nontraditional lipids with IS risk in Chinese adults.
Source: Lipids in Health and Disease - August 16, 2022 Category: Lipidology Authors: Minhua Tang, Qi Zhao, Kangqi Yi, Yiling Wu, Yu Xiang, Shuheng Cui, Xuyan Su, Yuting Yu, Genming Zhao and Yonggen Jiang Tags: Research Source Type: research

High lipoprotein(a) levels predict severity of coronary artery disease in patients hospitalized for acute myocardial infarction. Data from the French RICO survey
Lipoprotein(a) (Lp(a)) is an independent risk factor for atherosclerotic cardiovascular disease (ASCVD), including myocardial infarction (MI), ischemic stroke and peripheral artery disease, as well as for calcific aortic valve stenosis1-4. Lp(a) contributes to ASCVD risk via multiple mechanisms broadly classified in three categories, proatherogenic, proinflammatory, and potentially antifibrinolytic2. Epidemiological studies, including meta-analyses5,6, and genetic studies, strongly support a causal association between high levels of Lp(a) and increased risk of ASCVD.
Source: Journal of Clinical Lipidology - July 17, 2022 Category: Lipidology Authors: Michel Farnier, Fr édéric Chagué, Maud Maza, Florence Bichat, David Masson, Yves Cottin, Marianne Zeller Source Type: research

A Complex Case: Patient with Elevated Lp(a) and Debilitating Stroke
Nothing to disclose.
Source: Journal of Clinical Lipidology - July 1, 2022 Category: Lipidology Authors: Daniel Soffer, Jordan Lindekens Tags: Complex or Unusual Cases in Lipid Management Source Type: research

Lipid levels, apolipoproteins, and risk of incident atrial fibrillation in men: A report from the Kuopio Ischaemic Heart Disease Risk Factor Study (KIHD)
Atrial fibrillation (AF) is the most common of all sustained cardiac arrhythmias, with an estimated 6 –12 million people worldwide suffering from this condition in the US by 2050 and 17.9 million people in Europe by 20601. AF patients are at higher risk of cardiovascular disease, including congestive heart failure and stroke, and total and cardiac mortality2-4. Dyslipidemia [abnormal level of trig lycerides (TG) and/or total cholesterol (TC)] and dyslipoproteinemia [abnormal level of lipoproteins, e.g.
Source: Journal of Clinical Lipidology - April 23, 2022 Category: Lipidology Authors: Behnam Tajik, Tomi-Pekka Tuomainen, Rand Jarroch, Jussi Kauhanen, Gregory Y.H. Lip, Masoud Isanejad Tags: Journal of Clinical Lipidology Source Type: research

Increased admission serum total bile acids can be associated with decreased 3-month mortality in patients with acute ischemic stroke
Bile acids (BAs) not only play an important role in lipid metabolism and atherosclerosis but also have antiapoptotic and neuroprotective effects. However, few studies have focused on the relationship of the to...
Source: Lipids in Health and Disease - January 22, 2022 Category: Lipidology Authors: Lingling Huang, Ge Xu, Rong Zhang, Yadong Wang, Jiahui Ji, Fengdan Long and Yaming Sun Tags: Research Source Type: research

Fatty liver and cerebrovascular disease: plausible association and possible mechanisms
Purpose of review Nonalcoholic fatty liver disease (NAFLD) is a common comorbidity and has wide ranging extrahepatic manifestations, including through cardiometabolic pathways. As such, there is growing interest in the impact of NAFLD on cerebrovascular disease and brain health more broadly. In this review, we assess recent research into understanding the association between NAFLD and brain health while highlighting potential clinical implications. Recent findings Mechanistically, NAFLD is characterized by both a proinflammatory and proatherogenic state, which results in vascular inflammation and neurodegenerati...
Source: Current Opinion in Lipidology - December 29, 2021 Category: Lipidology Tags: NUTRITION AND METABOLISM: Edited by Frank M. Sacks and Majken K. Jensen Source Type: research

Hypertriglyceridemia is associated with better outcomes in patients hospitalized for ischemic stroke.
Lead Author's Financial Disclosure: Nothing to disclose.
Source: Journal of Clinical Lipidology - September 1, 2021 Category: Lipidology Authors: Genaro Velazquez, Hafeez Shaka, Hernan Marcos-Abdala, Juan Del Cid Fratti, Emmanuel Akuna Tags: Hypertriglyceridemia Source Type: research

Prostaglandin E2, 9S-, 13S-HODE and resolvin D1 are strongly associated with the post-stroke cognitive impairment
Publication date: Available online 10 June 2021Source: Prostaglandins & Other Lipid MediatorsAuthor(s): Dariusz Kotlęga, Barbara Peda, Arleta Drozd, Agnieszka Zembroń-Łacny, Ewa Stachowska, Jarosław Gramacki, Małgorzata Szczuko
Source: Prostaglandins and Other Lipid Mediators - June 12, 2021 Category: Lipidology Source Type: research

Triglyceride-lowering and Anti-inflammatory Mechanisms of Omega-3 Polyunsaturated Fatty Acids for Atherosclerotic Cardiovascular Risk Reduction
Atherosclerotic cardiovascular disease (ASCVD) is defined as acute coronary syndrome, stable angina, history of myocardial infarction, coronary or other arterial revascularization, ischemic stroke, transient ischemic attack, or peripheral arterial disease presumed to be of atherosclerotic origin.1 Despite continuous advances in medical intervention and surgical therapy for the treatment of ASCVD, the latter remains the leading cause of morbidity and mortality globally. In the United States, nearly 808,000 people died of ASCVD in 2014, translating to about 1 of every 3 deaths,2 and the death rate from ASCVD rose in 2015 by ...
Source: Journal of Clinical Lipidology - June 5, 2021 Category: Lipidology Authors: Qiyuan Keith Liu Tags: Review Article Source Type: research

JCL Roundtable: Global Think Tank on Lipoprotein(a)
Lipoprotein(a) operates in causal pathways to promote atherosclerosis, arterial thrombosis, and aortic stenosis. It has been associated with rare cases of nonatherosclerotic arterial thrombotic stroke at any age. Inherited variation of lipoprotein(a) levels substantially increases cardiovascular risk in 20% of people worldwide. Recent progress in identifying the risk associated with lipoprotein(a) and in pursuing effective treatment has led to a recent Global Think Tank including representatives from the European Atherosclerosis Society, American Heart Association, Preventive Cardiovascular Nurses Association, National Lip...
Source: Journal of Clinical Lipidology - May 1, 2021 Category: Lipidology Authors: Lisa L. Maher, S. Lale Tokg özoğlu, Eduardo J. Sanchez, James A. Underberg, John R. Guyton Source Type: research

Depression and cardiovascular disease
Purpose of review The purpose of this review is to outline the relationship between cardiovascular disease (CVD) and depression, both as a cause of and a result of CVD. Recent findings The prevalence of depression seems to be increasing in the general population. It is likely that depression will be even more of a problem for CVD patients in the post-COVID-19 pandemic era. New studies confirm the independent association of depression with later incident CVD, although perhaps not as strong as suggested by some previous studies. Depression seems to be becoming even more prevalent in CVD patients, with new...
Source: Current Opinion in Lipidology - April 30, 2021 Category: Lipidology Tags: LIPID METABOLISM Source Type: research

A cohort study on risk factors of high-density lipoprotein cholesterol hypolipidemia among urban Chinese adults
High-density lipoprotein cholesterol (HDL-C) hypolipidemia, a major type of dyslipidemia, has been associated with many kinds of diseases, such as stroke, coronary heart disease, obesity and diabetes, and has ...
Source: Lipids in Health and Disease - February 22, 2021 Category: Lipidology Authors: Fang Tang, Jian Wang, Stephen Nicholas, Dongfu Qian and Rugang Liu Tags: Research Source Type: research

Case Report: 68 yo Chinese-American woman with high HDL-C and ischemic stroke attributed to intracranial atherosclerotic stenosis
Atherosclerotic cardiovascular disease (ASCVD) events are the most common cause of death in the United States and for most individuals who experience these events, may be predicted by risk identification tools. ASCVD risk calculators enable a clinician-patient discussion and the presence of risk-enhancing factors may further inform decision-making with respect to preventive pharmacotherapy, especially statin prescription. In cases where the decision of whether to treat with medicine is unclear, coronary artery calcium scoring by computed tomography offers enhanced risk stratification and may allow both clinicians and patie...
Source: Journal of Clinical Lipidology - January 27, 2021 Category: Lipidology Authors: Jan Gong, Stephanie Byers Asher, Brett Cucchiara, Marina Cuchel, Daniel Soffer Tags: Case Report Source Type: research

The influence of CYP1A1 and CYP1A2 polymorphisms on stroke risk in the Chinese population
Stroke is a sudden disorder of cerebral blood circulation. Many studies have illustrated that dyslipidemia, hypertension, diabetes, smoking and excessive drinking are the traditional risk factors for stroke. T...
Source: Lipids in Health and Disease - October 12, 2020 Category: Lipidology Authors: Yan Mao, Lin Yang, Qian Chen, Guoqing Li, Yao Sun, Jiamin Wu, Zichao Xiong, Yuanwei Liu, Haiyue Li, Jianfeng Liu and Yong Zhang Tags: Research Source Type: research