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Specialty: Epidemiology

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Total 1093 results found since Jan 2013.

Serum neurofilament light chain, brain infarcts, and the risk of stroke: a prospective population-based cohort study
AbstractNeurofilament light chain (NfL), a neuron-specific protein, has been related to several neurodegenerative diseases. In addition, elevated levels of NfL have also been observed in patients admitted to the hospital for stroke, suggesting that NfL as a biomarker may extend well beyond neurodegenerative diseases. Therefore, using data from the Chicago Health and Aging Project (CHAP), a population-based cohort study, we prospectively investigated the association of serum NfL levels with incident stroke and brain infarcts. During a follow-up of 3603 person-years, 133 (16.3%) individuals developed incident stroke, includi...
Source: European Journal of Epidemiology - March 3, 2023 Category: Epidemiology Source Type: research

Venous thromboembolism in patients with idiopathic pulmonary fibrosis, based on nationwide claim data
CONCLUSION: Ischemic heart disease, ischemic stroke, and malignancy, especially lung cancer, were related to higher HR for VTE in IPF.PMID:36846942 | DOI:10.1177/17534666231155772
Source: Adv Data - February 27, 2023 Category: Epidemiology Authors: Jang Ho Lee Hoon Hee Lee Hyung Jun Park Seonok Kim Ye-Jee Kim Jae Seung Lee Ho Cheol Kim Source Type: research

Gamification of the National Institutes of Health Stroke Scale (NIHSS) for simulation training-a feasibility study
CONCLUSION: Game-based digital simulation training is a feasible alternative to standard in-person simulation training to acquire competence in NIHSS assessment. Gamification seemed to give an incentive to simulate considerably more and to perform the assessment faster, with equal accuracy.TRIAL REGISTRATION: The study was approved by the Norwegian Centre for Research Data (reference no. 543238).PMID:36810284 | DOI:10.1186/s41077-023-00245-4
Source: Adv Data - February 22, 2023 Category: Epidemiology Authors: Astrid Karina V Harring Jo R øislien Karianne Larsen Mona Guterud Helge Fagerheim Bugge Else Charlotte Sandset Dorte V Kristensen Maren Ranhoff Hov Source Type: research

The Relationship Between Major Food Sources of Fructose and Cardiovascular Outcomes: A Systematic Review and Dose-Response Meta-Analysis of Prospective Studies
In this study, we conducted a meta-analysis to examine potential dose-response relationships between such foods and CVD, coronary heart disease (CHD), and stroke morbidity and mortality. We systematically searched the literature indexed in PubMed, Embase, and the Cochrane Library from the inception of each database to February 10, 2022. We included prospective cohort studies analyzing the association between at least 1 dietary source of fructose and CVD, CHD, and stroke. Based on data from 64 included studies, summary HRs and 95% CIs were calculated for the highest intake category compared with the lowest, and dose-respons...
Source: Adv Data - February 21, 2023 Category: Epidemiology Authors: Tingting Sun Yabing Zhang Lin Ding Yonggang Zhang Tao Li Qian Li Source Type: research

Large Burden of Stroke Incidence in People with Cardiac Disease: A Linked Data Cohort Study
Source: Clinical Epidemiology - February 17, 2023 Category: Epidemiology Tags: Clinical Epidemiology Source Type: research

Age gap between stroke patients included in randomized clinical trials of acute revascularization therapy and those in population-based studies. A review
Background: The ongoing aging population in high-income countries is responsible for a dramatic rise in the number of elderly stroke patients in whom many questions remain regarding the use of acute revascularization therapy. This review aimed to compare stroke patients from population-based studies to those included in RCTs in terms of age. Summary: Population-based incidence studies conducted in high income that complied with the defined quality criteria were reviewed (period 1985-2020). RCTs of acute ischemic stroke therapy including intravenous thrombolysis (IVT) with either alteplase or tenecteplase and mechanical th...
Source: Neuroepidemiology - February 15, 2023 Category: Epidemiology Source Type: research

Association between baseline cardiovascular risk and incidence rates of major adverse cardiovascular events and malignancies in patients with psoriatic arthritis and psoriasis receiving tofacitinib
CONCLUSION: In tofacitinib-treated patients with PsA/PsO, increased ASCVD risk and baseline MetS were associated with higher IRs for MACE and malignancies. Our results support assessing CV risk in patients with PsA/PsO and suggest enhanced cancer monitoring in those with increased ASCVD risk.REGISTRATION CLINICALTRIALSGOV: NCT01877668/NCT01882439/NCT01976364/NCT00678210/NCT01710046/NCT01241591/NCT01186744/NCT01276639/NCT01309737/NCT01163253.PLAIN LANGUAGE SUMMARY: People who have psoriatic arthritis or psoriasis may have more heart-related problems and cancer if they have a higher risk of cardiovascular disease: A study in...
Source: Adv Data - February 13, 2023 Category: Epidemiology Authors: Lars E Kristensen Bruce Strober Denis Poddubnyy Ying-Ying Leung Hyejin Jo Kenneth Kwok Ivana Vranic Dona L Fleishaker Lara Fallon Arne Yndestad Dafna D Gladman Source Type: research

Short-term socioeconomic status shift and long-term cardiovascular outcomes in China: a population-based cohort study
Conclusion Short-term SES improvement is associated with better long-term cardiovascular outcome in China. High baseline SES might buffer out some unfavourable impact brought by moderate SES downshift. More comprehensive strategies should be considered in policy-making for socioeconomic development.
Source: Journal of Epidemiology and Community Health - February 9, 2023 Category: Epidemiology Authors: Lai, R., Li, R., Wang, T., Ju, J., Liu, Q., Zhang, J., Song, L., Xu, H. Tags: Open access Original research Source Type: research

Automatic electronic reporting improved the completeness of AMI and stroke incident surveillance in Tianjin, China: a modeling study
AMI and stroke are the leading causes of premature mortality and hospitalizations in China. Incidence data at the population level for the two diseases is limited and the reliability and completeness of the ex...
Source: Population Health Metrics - February 6, 2023 Category: Epidemiology Authors: Hong Xiao, Fang Liu and Joseph M. Unger Tags: Research Source Type: research

Zinc for infection prevention in children with sickle cell anemia: a randomized double-blind placebo-controlled trial
Blood Adv. 2023 Feb 3:bloodadvances.2022008539. doi: 10.1182/bloodadvances.2022008539. Online ahead of print.ABSTRACTData from small clinical trials in the USA and India suggest zinc supplementation reduces infection in adolescents and adults with sickle cell anemia (SCA), but no studies of zinc supplementation for infection prevention have been conducted in young children with SCA living in Africa, who have higher infection rates. We conducted a randomized double-blind placebo-controlled trial to assess the effectiveness of zinc supplementation for prevention of severe or invasive infections in Ugandan children 1.00-4.99 ...
Source: Adv Data - February 3, 2023 Category: Epidemiology Authors: Ruth Namazzi Robert O Opoka Andrea L Conroy Dibyadyuti Datta Abner Tagoola Caitlin Bond Michael J Goings Moon-Suhn Ryu Sarah E Cusick Nancy F Krebs Jeong Hoon Jang Wanzhu F Tu Russell E Ware Chandy C John Source Type: research

A Thrombin-Activated Peptide-Templated Nanozyme for Remedying Ischemic Stroke Via Thrombolytic and Neuroprotective Actions
This article is protected by copyright. All rights reserved.PMID:36730098 | DOI:10.1002/adma.202210144
Source: Adv Data - February 2, 2023 Category: Epidemiology Authors: Zhuoran Wang Yue Zhao Yaxin Hou Guoheng Tang Ruofei Zhang Yili Yang Xiyun Yan Kelong Fan Source Type: research