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Specialty: Epidemiology

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Total 1093 results found since Jan 2013.

Identifying applications of virtual reality to benefit the stroke translational pipeline
Brain Neurosci Adv. 2023 Jun 21;7:23982128231182506. doi: 10.1177/23982128231182506. eCollection 2023 Jan-Dec.ABSTRACTAs a leading cause of mortality and morbidity, stroke and its management have been studied extensively. Despite numerous pre-clinical studies identifying therapeutic targets, development of effective, specific pharmacotherapeutics remain limited. One significant limitation is a break in the translational pipeline - promising pre-clinical results have not always proven replicable in the clinic. Recent developments in virtual reality technology might help generate a better understanding of injury and recovery...
Source: Adv Data - June 26, 2023 Category: Epidemiology Authors: Matan Bone Maham Malik Siobhan Crilly Source Type: research

Acute reperfusion treatment and secondary prevention of cancer-related stroke: comprehensive overview and proposal of clinical algorithm
In conclusion, acute CRS remains a clinical challenge, with many patients suffering recurrent stroke, despite preventive measures. More randomized-controlled clinical trials are urgently needed to pinpoint the most effective management options for this subset of stroke patients.PMID:37342814 | PMC:PMC10278431 | DOI:10.1177/17562864231180717
Source: Adv Data - June 21, 2023 Category: Epidemiology Authors: Athina-Maria Aloizou Lina Palaiodimou Dimitra Aloizou Efthimios Dardiotis Ralf Gold Georgios Tsivgoulis Christos Krogias Source Type: research

The Positive Predictive Value of Pediatric Stroke Diagnoses in Administrative Data: A Retrospective Validation Study
Source: Clinical Epidemiology - June 20, 2023 Category: Epidemiology Tags: Clinical Epidemiology Source Type: research

Cheese consumption and multiple health outcomes: an umbrella review and updated meta-analysis of prospective studies
Adv Nutr. 2023 Jun 14:S2161-8313(23)01328-5. doi: 10.1016/j.advnut.2023.06.007. Online ahead of print.ABSTRACTThis umbrella review aims to provide a systematic and comprehensive overview of current evidence from prospective studies on the diverse health effects of cheese consumption. We searched PubMed, Embase, and Cochrane Library to identify meta-analyses/pooled analyses of prospective studies examining the associations between cheese consumption and major health outcomes from inception to August 31, 2022. We reanalyzed and updated previous meta-analyses and performed de novo meta-analyses with recently published prospec...
Source: Adv Data - June 16, 2023 Category: Epidemiology Authors: Mingjie Zhang Xiaocong Dong Zihui Huang Xue Li Yue Zhao Yingyao Wang Huilian Zhu Aiping Fang Edward L Giovannucci Source Type: research

Bone Marrow Mesenchymal Stem Cell-Derived Dermcidin-Containing Migrasomes enhance LC3-Associated Phagocytosis of Pulmonary Macrophages and Protect against Post-Stroke Pneumonia
Adv Sci (Weinh). 2023 May 28:e2206432. doi: 10.1002/advs.202206432. Online ahead of print.ABSTRACTPneumonia is one of the leading causes of death in patients with acute ischemic stroke (AIS). Antibiotics fail to improve prognosis of patients with post-stroke pneumonia, albeit suppressing infection, due to adverse impacts on the immune system. The current study reports that bone marrow mesenchymal stem cells (BM-MSC) downregulate bacterial load in the lungs of stroke mice models. RNA-sequencing of the lung from BM-MSC-treated stroke models indicates that BM-MSC modulates pulmonary macrophage activities after cerebral ischem...
Source: Adv Data - May 28, 2023 Category: Epidemiology Authors: Tiemei Li Xiaotao Su Pinglan Lu Xinmei Kang Mengyan Hu Chunyi Li Shisi Wang Danli Lu Shishi Shen Huipeng Huang Yuxin Liu Xiaohui Deng Wei Cai Lei Wei Zhengqi Lu Source Type: research

Serious neurological adverse events following immunization against SARS-CoV-2: a narrative review of the literature
Ther Adv Drug Saf. 2023 May 21;14:20420986231165674. doi: 10.1177/20420986231165674. eCollection 2023.ABSTRACTAmid the coronavirus disease 2019 (COVID-19) pandemic, massive immunization campaigns became the most promising public health measure. During clinical trials, certain neurological adverse effects following immunization (AEFIs) were observed; however, acceptable safety profiles lead to emergency authorization for the distribution and use of the vaccines. To contribute to pharmacovigilance and lessen the potential negative impact that vaccine hesitancy would have on immunization programs, we conducted a review of the...
Source: Adv Data - May 24, 2023 Category: Epidemiology Authors: Sara Eslait-Olaciregui Kevin Llin ás-Caballero David Pati ño-Manjarrés Thomas Urbina-Ariza Juan Fernando Cediel-Becerra Camilo Alberto Dom ínguez-Domínguez Source Type: research

Single-Cell RNA Sequencing and Spatial Transcriptomics Reveal Pathogenesis of Meningeal Lymphatic Dysfunction after Experimental Subarachnoid Hemorrhage
Adv Sci (Weinh). 2023 May 21:e2301428. doi: 10.1002/advs.202301428. Online ahead of print.ABSTRACTSubarachnoid hemorrhage (SAH) is a devastating subtype of stroke with high mortality and disability rate. Meningeal lymphatic vessels (mLVs) are a newly discovered intracranial fluid transport system and are proven to drain extravasated erythrocytes from cerebrospinal fluid into deep cervical lymph nodes after SAH. However, many studies have reported that the structure and function of mLVs are injured in several central nervous system diseases. Whether SAH can cause mLVs injury and the underlying mechanism remain unclear. Here...
Source: Adv Data - May 22, 2023 Category: Epidemiology Authors: Xiaoyu Wang Anke Zhang Qian Yu Zelin Wang Junjie Wang Penglei Xu Yibo Liu Jianan Lu Jingwei Zheng Huaming Li Yangjian Qi Jiahao Zhang Yuanjian Fang Shenbin Xu Jingyi Zhou Kaikai Wang Sheng Chen Jianmin Zhang Source Type: research

A brazilian nationwide multicenter study on deficiency of deaminase-2 (DADA2)
CONCLUSION: The low number of patients diagnosed with DADA2 in Brazil reinforces the need for disease awareness for this condition. Moreover, the absence of guidelines for diagnosis and management is also necessary (t).PMID:37217999 | DOI:10.1186/s42358-023-00303-5
Source: Adv Data - May 22, 2023 Category: Epidemiology Authors: Adriana Melo Luciana Martins de Carvalho Virginia Paes Leme Ferriani Andr é Cavalcanti Simone Appenzeller Val éria Rossato Oliveira Herberto Chong Neto Nelson Augusto Ros ário Fabiano de Oliveira Poswar Matheus Xavier Guimaraes Cristina Maria Kokron Ra Source Type: research

Single-Cell RNA Sequencing and Spatial Transcriptomics Reveal Pathogenesis of Meningeal Lymphatic Dysfunction after Experimental Subarachnoid Hemorrhage
Adv Sci (Weinh). 2023 May 21:e2301428. doi: 10.1002/advs.202301428. Online ahead of print.ABSTRACTSubarachnoid hemorrhage (SAH) is a devastating subtype of stroke with high mortality and disability rate. Meningeal lymphatic vessels (mLVs) are a newly discovered intracranial fluid transport system and are proven to drain extravasated erythrocytes from cerebrospinal fluid into deep cervical lymph nodes after SAH. However, many studies have reported that the structure and function of mLVs are injured in several central nervous system diseases. Whether SAH can cause mLVs injury and the underlying mechanism remain unclear. Here...
Source: Adv Data - May 22, 2023 Category: Epidemiology Authors: Xiaoyu Wang Anke Zhang Qian Yu Zelin Wang Junjie Wang Penglei Xu Yibo Liu Jianan Lu Jingwei Zheng Huaming Li Yangjian Qi Jiahao Zhang Yuanjian Fang Shenbin Xu Jingyi Zhou Kaikai Wang Sheng Chen Jianmin Zhang Source Type: research

Comment on: Chen et al. Trends and ethnic differences in stroke recurrence and mortality in a bi-ethnic population, 2000-2019: a novel application of an illness-death model. Annals of Epidemiology, in press
Ann Epidemiol. 2023 May 16:S1047-2797(23)00088-1. doi: 10.1016/j.annepidem.2023.05.003. Online ahead of print.NO ABSTRACTPMID:37201668 | DOI:10.1016/j.annepidem.2023.05.003
Source: Annals of Epidemiology - May 18, 2023 Category: Epidemiology Authors: Sebastien Haneuse Emily Rencsok Jay S Kaufman Source Type: research

Artificially sweetened beverages and health outcomes: an umbrella review
CONCLUSIONS: The consumption of ASBs was associated with a higher risk of obesity, type II diabetes, all-cause mortality, hypertension, and cardiovascular disease incidence. However, further cohort studies and clinical trials in humans are still needed to understand the impact of ASBs on health outcomes.PMID:37187453 | DOI:10.1016/j.advnut.2023.05.010
Source: Adv Data - May 15, 2023 Category: Epidemiology Authors: Cristina Diaz Leandro F M Rezende Angelo Sabag Dong Hoon Lee Gerson Ferrari Edward L Giovannucci Juan Pablo Rey-Lopez Source Type: research