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Specialty: Epidemiology
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Total 1093 results found since Jan 2013.
The association of baseline depressive symptoms and stress on withdrawal in a national longitudinal cohort: The REGARDS Study
CONCLUSIONS: Depressive symptoms, but not perceived stress, were significantly associated with withdrawal from a large study. Prevalence of depressive symptoms at baseline is likely an important indicator of participant retention in large prospective cohorts.PMID:37182817 | DOI:10.1016/j.annepidem.2023.05.007
Source: Annals of Epidemiology - May 14, 2023 Category: Epidemiology Authors: Chen Lin Virginia J Howard Hely D Nanavati Suzanne E Judd George Howard Source Type: research
Identification, characterization, and engineering of glycosylation in thrombolyticsa
Biotechnol Adv. 2023 May 12:108174. doi: 10.1016/j.biotechadv.2023.108174. Online ahead of print.ABSTRACTCardiovascular diseases, such as myocardial infarction, ischemic stroke, and pulmonary embolism, are the most common causes of disability and death worldwide. Blood clot hydrolysis by thrombolytic enzymes and thrombectomy are key clinical interventions. The most widely used thrombolytic enzyme is alteplase, which has been used in clinical practice since 1986. Another clinically used thrombolytic protein is tenecteplase, which has modified epitopes and engineered glycosylation sites, suggesting that carbohydrate modifica...
Source: Adv Data - May 14, 2023 Category: Epidemiology Authors: Martin Toul Veronika Slonkova Jan Mican Adam Urminsky Maria Tomkova Erik Sedlak David Bednar Jiri Damborsky Lenka Hernychova Zbynek Prokop Source Type: research
Patient Management and Clinical Outcomes Associated with a Recorded Diagnosis of Stage 3 Chronic Kidney Disease: The REVEAL-CKD Study
CONCLUSIONS: A recorded CKD diagnosis was associated with significant improvements in CKD management and monitoring practices and attenuated eGFR decline. Recorded diagnosis of stage 3 CKD is an important first step to reduce the risk of disease progression and minimize adverse clinical outcomes.TRIAL REGISTRATION: ClinicalTrials.gov identifier, NCT04847531.PMID:37133647 | DOI:10.1007/s12325-023-02482-5
Source: Adv Data - May 3, 2023 Category: Epidemiology Authors: Navdeep Tangri Emily J Peach Stefan Franz én Salvatore Barone Pamela R Kushner Source Type: research
A Bioinspired Manganese-Organic Framework Ameliorates Ischemic Stroke through its Intrinsic Nanozyme Activity and Upregulating Endogenous Antioxidant Enzymes
Adv Sci (Weinh). 2023 May 2:e2206854. doi: 10.1002/advs.202206854. Online ahead of print.ABSTRACTFollowing stroke, oxidative stress induced by reactive oxygen species (ROS) aggravates neuronal damage and enlarges ischemic penumbra, which is devastating to stroke patients. Nanozyme-based antioxidants are emerging to treat stroke through scavenging excessive ROS. However, most of nanozymes cannot efficiently scavenge ROS in neuronal cytosol and mitochondria, due to low-uptake abilities of neurons and barriers of organelle membranes, significantly limiting nanozymes' neuroprotective effects. To overcome this limitation, a man...
Source: Adv Data - May 2, 2023 Category: Epidemiology Authors: Jian Wang Yang Wang Xiakeerzhati Xiaohalati Qiangfei Su Jingwei Liu Bo Cai Wen Yang Zheng Wang Lin Wang Source Type: research
Mental Health and Quality of Life in Pulmonary Embolism: A Literature Review
Adv Respir Med. 2023 Apr 20;91(2):174-184. doi: 10.3390/arm91020015.ABSTRACTPulmonary embolismis an acute disease with chronic complications and, although it is not considered a chronic disease, it requires close follow-up. The scope of the present literature review is to decode the existing data concerning quality of life and the mental health impact of PE during the acute and long-term phases of the disease. The majority of studies reported impaired quality of life in patients with PE when compared to population norms, both in the acute phase and >3 months after PE. Quality of life improves over time, irrespectively o...
Source: Adv Data - April 27, 2023 Category: Epidemiology Authors: Niki Gkena Paraskevi Kirgou Konstantinos I Gourgoulianis Foteini Malli Source Type: research
Stroke Mortality Among Black and White Adults Aged ≥35 Years Before and During the COVID-19 Pandemic - United States, 2015-2021
MMWR Morb Mortal Wkly Rep. 2023 Apr 21;72(16):431-436. doi: 10.15585/mmwr.mm7216a4.ABSTRACTStroke is the fifth leading cause of death and a leading cause of long-term disability in the United States (1). Although stroke death rates have declined since the 1950s, age-adjusted rates remained higher among non-Hispanic Black or African American (Black) adults than among non-Hispanic White (White) adults (1,2). Despite intervention efforts to reduce racial disparities in stroke prevention and treatment through reducing stroke risk factors, increasing awareness of stroke symptoms, and improving access to treatment and care for s...
Source: MMWR Morb Mortal Wkl... - April 21, 2023 Category: Epidemiology Authors: Quanhe Yang Xin Tong Linda Schieb F átima Coronado Robert Merritt Source Type: research
Diagnosis of Coronary Artery Disease based on Machine Learning algorithms Support Vector Machine, Artificial Neural Network, and Random Forest
CONCLUSION: In this study, it was shown that machine learning algorithms can be used with high accuracy to detect CAD. Thus, it allows physicians to perform timely preventive treatment in patients with CAD.PMID:37057235 | PMC:PMC10086656 | DOI:10.4103/abr.abr_383_21
Source: Adv Data - April 14, 2023 Category: Epidemiology Authors: Saeed Saeedbakhsh Mohammad Sattari Maryam Mohammadi Jamshid Najafian Farzaneh Mohammadi Source Type: research
