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Specialty: Cardiology
Procedure: Carotid Endarterectomy

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Total 244 results found since Jan 2013.

A comparison of two different management plans for patients requiring both carotid endarterectomy and coronary artery bypass grafting
CONCLUSIONS: For patients requiring CEA and CABG, performing both operations under general anaesthesia in the same session was safer than initially performing CEA under cervical block anaesthesia followed by CABG under general anaesthesia.PMID:33729273 | DOI:10.5830/CVJA-2020-042
Source: Cardiovascular Journal of Africa - March 17, 2021 Category: Cardiology Authors: Ata Niyazi Ecevit Okay Guven Karaca Mehmet Kalender Murat Bekmezci Mehmet Ali Sungur Osman Tansel Dar çın Source Type: research

Virtual Transcriptomics: Noninvasive Phenotyping of Atherosclerosis by Decoding Plaque Biology From Computed Tomography Angiography Imaging
CONCLUSIONS: The results of this pilot study show that atherosclerotic plaque phenotyping by image analysis of conventional computed-tomography angiography can elucidate the molecular signature of atherosclerotic lesions in a multiscale setting. The study holds promise for optimized personalized therapy in the prevention of myocardial infarction and ischemic stroke, which warrants further investigations in larger cohorts.PMID:33691476 | DOI:10.1161/ATVBAHA.121.315969
Source: Arteriosclerosis, Thrombosis and Vascular Biology - March 11, 2021 Category: Cardiology Authors: Andrew J Buckler Eva Karl öf Mariette Lengquist T Christian Gasser Lars Maegdefessel Ljubica Perisic Matic Ulf Hedin Source Type: research

Impact of intraoperative neurologic deficits in carotid endarterectomy under regional anesthesia.
Conclusions. Neurologic deficits during carotid clamping are a predictor of perioperative stroke. Body mass index > 30 kg/m2, a lower degree of ipsilateral stenosis, and a higher degree of contralateral stenosis are independent predictors of neurologic deficits and, therefore, might play a role in the prevention of procedure-related stroke. PMID: 33487041 [PubMed - as supplied by publisher]
Source: Scandinavian Cardiovascular Journal - January 27, 2021 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Overview of evidence on the effectiveness and safety of dual-layer stents in carotid artery disease.
CONCLUSIONS: Despite the theoretic advantage of reducing the risk for procedural embolic events when compared to conventional stents, high quality evidence is scarce. Also, safety issues regarding DLS in the emergency setting have been raised, particularly for thrombotic complications. Additional data from well-designed Randomized Controlled Trials are needed to assert the true value of DLS. PMID: 33337115 [PubMed - as supplied by publisher]
Source: International Angiology - December 20, 2020 Category: Cardiology Tags: Int Angiol Source Type: research

The Stem Cell Pluripotency Genes Klf4 and Oct4 Regulate Complex SMC Phenotypic Changes Critical in Late-Stage Atherosclerotic Lesion Pathogenesis.
Conclusions: Taken together, these results provide evidence that SMC-derived cells within advanced mouse and human atherosclerotic lesions exhibit far greater phenotypic plasticity than generally believed, with Klf4 regulating transition to multiple phenotypes including Lgals3+ osteogenic cells likely to be detrimental for late stage atherosclerosis plaque pathogenesis. PMID: 32674599 [PubMed - as supplied by publisher]
Source: Circulation - July 16, 2020 Category: Cardiology Authors: Alencar GF, Owsiany KM, K S, Sukhavasi K, Mocci G, Nguyen A, Williams CM, Shamsuzzaman S, Mokry M, Henderson CA, Haskins R, Baylis RA, Finn AV, McNamara CA, Zunder ER, Venkata V, Pasterkamp G, Björkegren J, Bekiranov S, Owens GK Tags: Circulation Source Type: research

Role of Carotid Artery Stenting in Prevention of Stroke for Asymptomatic Carotid Stenosis: Bayesian Cross-Design and Network Meta-Analyses.
CONCLUSIONS: A similar risk for periprocedural MI between CEA and CAS in NRCSs suggested that concerns about periprocedural MI accompanied by CEA might not matter in real-world practice when preoperative evaluation and management are working. Maybe the benefits of CAS over MT have been overestimated considering advances in medical therapy within10-year gap between CEA-versus-MT and CEA-versus-CAS studies. PMID: 32096354 [PubMed - as supplied by publisher]
Source: Korean Circulation Journal - February 27, 2020 Category: Cardiology Tags: Korean Circ J Source Type: research

Prognostic factors of long-term survival to guide selection of asymptomatic patients for carotid endarterectomy.
CONCLUSIONS: The presence of one or more prognostic factors as well as the various risk prediction models can guide selection of ACS patient subgroups for which a prophylactic CEA should or should not be offered. Decisions to offer prophylactic CEA should weigh in factors like surgeon's experience and hospital expertise/volume. Asymptomatic patients not expected to live long enough to benefit from the procedure should not be considered for CEA, but should be offered best medical treatment. PMID: 31814375 [PubMed - as supplied by publisher]
Source: International Angiology - December 11, 2019 Category: Cardiology Tags: Int Angiol Source Type: research

Management of Asymptomatic Carotid Artery Stenosis
AbstractPurpose of reviewThe goal of this paper is to provide the reader with a review of the evidence supporting the surgical and medical management of patients with asymptomatic internal carotid artery (ICA) stenosis.Recent findingsBased on the results of earlier clinical trials, surgical intervention with carotid endarterectomy (CEA) has long been the preferred method of management for patients with asymptomatic severe carotid stenosis. Carotid artery stenting (CAS) is another less invasive surgical option that has similar outcomes over the long-term. However, more recent improvements in medical management have reduced ...
Source: Current Treatment Options in Cardiovascular Medicine - December 8, 2019 Category: Cardiology Source Type: research

Immune cells in carotid artery plaques: what can we learn from endarterectomy specimens?
CONCLUSIONS: Since the destabilization of the atherosclerotic plaque is a multifactorial process, a combination of various methods should be used to characterize the unstable plaques more accurately. In this context, studies characterizing plaque content from a cellular point ofview could elucidate some processes underlying the plaque progression. Together with morphological evaluation, these analyses could enable more precise assessment of plaque stability. PMID: 31782285 [PubMed - as supplied by publisher]
Source: International Angiology - December 1, 2019 Category: Cardiology Tags: Int Angiol Source Type: research