Virtual Transcriptomics: Noninvasive Phenotyping of Atherosclerosis by Decoding Plaque Biology From Computed Tomography Angiography Imaging

CONCLUSIONS: The results of this pilot study show that atherosclerotic plaque phenotyping by image analysis of conventional computed-tomography angiography can elucidate the molecular signature of atherosclerotic lesions in a multiscale setting. The study holds promise for optimized personalized therapy in the prevention of myocardial infarction and ischemic stroke, which warrants further investigations in larger cohorts.PMID:33691476 | DOI:10.1161/ATVBAHA.121.315969

Source: Arteriosclerosis, Thrombosis and Vascular Biology - March 11, 2021 Category: Cardiology Authors: Andrew J Buckler Eva Karl öf Mariette Lengquist T Christian Gasser Lars Maegdefessel Ljubica Perisic Matic Ulf Hedin Source Type: research