Filtered By:
Procedure: Gastroschisis Repair

This page shows you your search results in order of relevance. This is page number 13.

Order by Relevance | Date

Total 4990 results found since Jan 2013.

Neuroinflammatory biomarkers: From stroke diagnosis and prognosis to therapy
This article is part of a Special Issue entitled: Neuro Inflammation edited by Helga E. de Vries and Markus Schwaninger.
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - October 31, 2015 Category: Molecular Biology Source Type: research

Left Subclavian Arterial Coverage and Stroke During Thoracic Aortic Endografting: A Systematic Review.
We report a systematic review of 63 studies comprising more than 3,000 patients. We conclude that stroke risk after TEVAR is increased by LSA coverage, and that LSA revascularization reduces stroke risk. LSA revascularization may lower the rate of posterior stroke. TEVAR for aneurysm is associated with increased stroke risk compared to TEVAR for dissection. PMID: 26588864 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - November 14, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Waterford SD, Chou D, Bombien R, Uzun I, Shah A, Khoynezhad A Tags: Ann Thorac Surg Source Type: research

Variability in Motor and Language Recovery during the Acute Stroke Period
Background: Most stroke recovery occurs by 90 days after onset, with proportional recovery models showing an achievement of about 70% of the maximal remaining recovery. Little is known about recovery during the acute stroke period. Moreover, data are described for groups, not for individuals. In this observational cohort study, we describe for the first time the daily changes of acute stroke patients with motor and/or language deficits over the first week after stroke onset. Methods: Patients were enrolled within 24-72 h after stroke onset with upper extremity hemiparesis, aphasia, or both, and were tested daily until day ...
Source: Cerebrovascular Diseases Extra - March 22, 2016 Category: Neurology Source Type: research

Ischemic Post-Conditioning Induces Post-Stroke Neuroprotection via Hsp70-Mediated Proteasome Inhibition and Facilitates Neural Progenitor Cell Transplantation
AbstractIn view of the failure of pharmacological therapies, alternative strategies promoting post-stroke brain repair are needed. Post-conditioning is a potentially promising therapeutic strategy, which induces acute neuroprotection against ischemic injury. To elucidate longer lasting actions of ischemic post-conditioning, mice were exposed to a 60-min stroke and post-conditioning by an additional 10-min stroke that was induced 10  min after reperfusion onset. Animals were sacrificed 24 h or 28 days post-stroke. Post-conditioning reduced infarct volume and neurological deficits 24 h post-stroke, enhancing blood-brain ...
Source: Molecular Neurobiology - October 2, 2016 Category: Neurology Source Type: research

Contrasting roles of immune cells in tissue injury and repair in stroke: The dark and bright side of immunity in the brain
Publication date: Available online 27 February 2017 Source:Neurochemistry International Author(s): Aditya Rayasam, Martin Hsu, Gianna Hernández, Julie Kijak, Anders Lindstedt, Christian Gerhart, Matyas Sandor, Zsuzsanna Fabry Despite considerable efforts in research and clinical studies, stroke is still one of the leading causes of death and disability worldwide. Originally, stroke was considered a vascular thrombotic disease without significant immune involvement. However, over the last few decades it has become increasingly obvious that the immune responses can significantly contribute to both tissue injury and protect...
Source: Neurochemistry International - February 26, 2017 Category: Neuroscience Source Type: research

Pivotal neuroinflammatory and therapeutic role of high mobility group box 1 in ischemic stroke.
Abstract Stroke is a major cause of mortality and disability worldwide. Stroke is a frequent and severe neurovascular disorder. The main cause of stroke is atherosclerosis, and the most common risk factor for atherosclerosis is hypertension. Therefore, prevention and treatment of stroke are crucial issues in humans. High mobility group box 1 (HMGB1) is non-histone nuclear protein that is currently one of the crucial pro-inflammatory alarmin in ischemic stroke (IS). It is instantly released from necrotic cells in the ischemic core and activates an early inflammatory response. HMGB1 may signal via its putative recep...
Source: Bioscience Reports - October 20, 2017 Category: Biomedical Science Authors: Richard SA, Sackey M, Su Z, Xu H Tags: Biosci Rep Source Type: research

Oxidative stress and DNA damage after cerebral ischemia: Potential therapeutic targets to preserve the genome and improve stroke recovery.
Abstract The past two decades have witnessed remarkable advances in oxidative stress research, particularly in the context of ischemic brain injury. Oxidative stress in ischemic tissues compromises the integrity of the genome, resulting in DNA lesions, cell death in neurons, glial cells, and vascular cells, and impairments in neurological recovery after stroke. As DNA is particularly vulnerable to oxidative attack, cells have evolved the ability to induce multiple DNA repair mechanisms, including base excision repair (BER), nucleotide excision repair (NER) and non-homogenous endpoint jointing (NHEJ). Defective DNA...
Source: Neuropharmacology - November 8, 2017 Category: Drugs & Pharmacology Authors: Li P, Anne Stetler R, Leak RK, Shi Y, Li Y, Yu W, Bennett MVL, Chen J Tags: Neuropharmacology Source Type: research

Glial scars are permeable to the neurotoxic environment of chronic stroke infarcts.
Abstract Following stroke, the damaged tissue undergoes liquefactive necrosis, a stage of infarct resolution that lasts for months, although the exact length of time is currently unknown. One method of repair involves reactive astrocytes and microglia forming a glial scar to compartmentalize the area of liquefactive necrosis from the rest of the brain. The formation of the glial scar is a critical component of the healing response to stroke, as well as other central nervous system (CNS) injuries. The goal of this study was to evaluate the toxicity of the extracellular fluid present in areas of liquefactive necrosi...
Source: Neurobiology of Disease - January 10, 2018 Category: Neurology Authors: Zbesko JC, Nguyen TV, Yang T, Frye JB, Hussain O, Hayes M, Chung A, Anthony Day W, Stepanovic K, Krumberger M, Mona J, Longo FM, Doyle KP Tags: Neurobiol Dis Source Type: research

Post Stroke Cognitive Impairment and Hippocampal Neurovascular Remodeling: The Impact of Diabetes and Sex.
Abstract Diabetes increases the risk and severity of cognitive impairment, especially after ischemic stroke. Pathological remodeling of the cerebrovasculature has been postulated to contribute to poor neuronal repair and worsened cognitive deficits in diabetes. However, little is known about the effect of diabetes on the vascularization of hippocampus, a domain critical to memory and learning. Therefore we had two aims for this study: 1) to determine the impact of diabetes on hippocampal neurovascular remodeling and the resulting cognitive impairment after stroke using two models with varying disease severity, and...
Source: American Journal of Physiology. Heart and Circulatory Physiology - August 17, 2018 Category: Physiology Authors: Ward R, Valenzuela JP, Li W, Dong G, Fagan SC, Ergul A Tags: Am J Physiol Heart Circ Physiol Source Type: research

Toll-Like Receptor 4 Regulates Subventricular Zone Proliferation and Neuroblast Migration after Experimental Stroke.
Abstract Ischemic stroke is one of the leading causes of death and disability with an urgent need for innovative therapies, especially targeting the chronic phase. New evidence has emerged showing that Toll-Like Receptor 4 (TLR4), a key mediator of brain damage after stroke, may be involved in brain repair by neurogenesis modulation. The aim of this study is to analyze the role of TLR4 in the different stages of neurogenesis initiated in the subventricular zone (SVZ) over time after stroke in mice. Wildtype and TLR4-deficient mice underwent experimental ischemia, and neural stem/progenitor cells (NSPCs) proliferat...
Source: Brain, Behavior, and Immunity - May 2, 2019 Category: Neurology Authors: Palma-Tortosa S, Hurtado O, Miguel Pradillo J, Ferreras-Martín R, García-Yébenes I, García-Culebras A, Moraga A, Moro MÁ, Lizasoain I Tags: Brain Behav Immun Source Type: research

Role of bone marrow-derived macrophages (BMDMs) in neurovascular interactions during stroke
Publication date: Available online 27 May 2019Source: Neurochemistry InternationalAuthor(s): Akriti Srivastava, Pranay Srivastava, Rajkumar VermaAbstractStroke is a leading cause of disability worldwide and hence remains a major medical concern. Besides several pathological features, such as excitotoxicity, peri-infarct depolarization, acidosis, reactive oxygen species generation, apoptosis, and necrosis, dysregulation of the immune system severely affects stroke outcomes. After stroke onset, microglia – the brain-resident macrophage immune cells – and peripheral immune cells affect stoke injury/recovery by releasing p...
Source: Neurochemistry International - May 28, 2019 Category: Neuroscience Source Type: research

Inhibition of CD147 Improves Oligodendrogenesis and Promotes White Matter Integrity and Functional Recovery in Mice after Ischemic Stroke.
In conclusion, inhibition of CD147 promotes long-term functional recovery after stroke, at least in part, by enhancing oligodendrogenesis and white matter repair. PMID: 31356925 [PubMed - as supplied by publisher]
Source: Brain, Behavior, and Immunity - July 25, 2019 Category: Neurology Authors: Liu S, Jin R, Xiao AY, Zhong W, Li G Tags: Brain Behav Immun Source Type: research

The Local and Peripheral Immune Responses to Stroke: Implications for Therapeutic Development
AbstractThe immune response to stroke is an exciting target for future stroke therapies. Stroke is a leading cause of morbidity and mortality worldwide, and clot removal (mechanical or pharmacological) to achieve tissue reperfusion is the only therapy currently approved for patient use. Due to a short therapeutic window and incomplete effectiveness, however, many patients are left with infarcted tissue that stimulates inflammation. Although this is critical to promote repair, it can also damage surrounding healthy brain tissue. In addition, acute immunodepression and subsequent infections are common and are associated with...
Source: Neurotherapeutics - March 18, 2020 Category: Neurology Source Type: research

Brachiocephalic artery dissection is a marker of stroke after acute type A aortic dissection repair
ConclusionBCA dissection was an independent risk factor of stroke after ATAAD repair.
Source: Journal of Cardiac Surgery - January 13, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Tomoki Cho, Keiji Uchida, Keiichiro Kasama, Daisuke Machida, Tomoyuki Minami, Shota Yasuda, Yusuke Matsuki, Shinichi Suzuki, Munetaka Masuda Tags: ORIGINAL ARTICLE Source Type: research