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Total 4990 results found since Jan 2013.

Coagulopathy signature precedes and predicts severity of end-organ heat stroke pathology in a mouse model.
CONCLUSIONS: Heat stroke-induced coagulopathy may be a driving mechanistic force in heat stroke pathology, especially when exacerbated by prior infection. Coagulation markers may serve as accessible biomarkers for heat stroke severity and therapeutic strategies. PMID: 32367690 [PubMed - as supplied by publisher]
Source: Thrombosis and Haemostasis - May 3, 2020 Category: Hematology Authors: Proctor EA, Dineen SM, Van Nostrand SC, Kuhn MK, Barrett CD, Brubaker DK, Yaffe MB, Lauffenburger DA, Leon LR Tags: J Thromb Haemost Source Type: research

Neuroanatomy and severity of stroke in patients with type A aortic dissection
ConclusionsStrokes associated with ATAAD are severe at presentation resulting in significant disability. One in 10 strokes is due to LVO and potentially amenable to endovascular treatment. Heterogeneity in both location and etiology of stroke makes prevention challenging. Future trials may evaluate the role of early neuroimaging and simultaneous treatment of stroke given advancements in endovascular therapy.
Source: Journal of Cardiac Surgery - November 17, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Akash Fichadiya, Bijoy K. Menon, Alexander J. Gregory, Ericka Teleg, Jehangir J. Appoo Tags: ORIGINAL ARTICLE Source Type: research

Interactions between the Autonomic Nervous System and the Immune System after Stroke
Compr Physiol. 2022 Jun 29;12(3):3665-3704. doi: 10.1002/cphy.c210047.ABSTRACTAcute stroke is one of the leading causes of morbidity and mortality worldwide. Stroke-induced immune-inflammatory response occurs in the perilesion areas and the periphery. Although stroke-induced immunosuppression may alleviate brain injury, it hinders brain repair as the immune-inflammatory response plays a bidirectional role after acute stroke. Furthermore, suppression of the systemic immune-inflammatory response increases the risk of life-threatening systemic bacterial infections after acute stroke. Therefore, it is essential to explore the ...
Source: Comprehensive Physiology - June 29, 2022 Category: Physiology Authors: Li Zhu Leo Huang Anh Le Tom J Wang Jiewen Zhang Xuemei Chen Junmin Wang Jian Wang Chao Jiang Source Type: research