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Therapy: Vagus Nerve Stimulation Therapy

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Total 158 results found since Jan 2013.

TECHNIQUES Vagus Nerve Stimulation and the Cardiovascular System
The vagus nerve plays an important role in maintaining physiological homeostasis, which includes reflex pathways that regulate cardiac function. The link between vagus nerve activity and the high-frequency component of heart rate variability (HRV) has been well established, correlating with vagal tone. Recently, vagus nerve stimulation (VNS) has been investigated as a therapeutic for a multitude of diseases, such as treatment-resistant epilepsy, rheumatoid arthritis, Crohn's disease, and asthma. Because of the vagus nerve's innervation of the heart, VNS has been identified as a potential therapy for cardiovascular disorder...
Source: Cold Spring Harbor perspectives in medicine - February 2, 2020 Category: Research Authors: Capilupi, M. J., Kerath, S. M., Becker, L. B. Tags: Bioelectronic Medicine TECHNIQUES Source Type: research

Transcutaneous Auricular Vagus Nerve Stimulation-Paired Rehabilitation for Oromotor Feeding Problems in Newborns: An Open-Label Pilot Study
Neonates born premature or who suffer brain injury at birth often have oral feeding dysfunction and do not meet oral intake requirements needed for discharge. Low oral intake volumes result in extended stays in the hospital (>2 months) and can lead to surgical implant and explant of a gastrostomy tube (G-tube). Prior work suggests pairing vagus nerve stimulation (VNS) with motor activity accelerates functional improvements after stroke, and transcutaneous auricular VNS (taVNS) has emerged as promising noninvasive form of VNS. Pairing taVNS with bottle-feeding rehabilitation may improve oromotor coordination and lead to ...
Source: Frontiers in Human Neuroscience - March 17, 2020 Category: Neuroscience Source Type: research

α7nAchR mediates transcutaneous auricular vagus nerve stimulation-induced neuroprotection in a rat model of ischemic stroke by enhancing axonal plasticity
Publication date: Available online 19 May 2020Source: Neuroscience LettersAuthor(s): Jiani Li, Qinbin Zhang, Sheng Li, Lingchuan Niu, Jingxi Ma, Lan Wen, Lina Zhang, Changqing Li
Source: Neuroscience Letters - May 20, 2020 Category: Neuroscience Source Type: research

Vagus Nerve Stimulation Promotes Cortical Reorganization and Reduces Task-Dependent Calorie Intake in Male and Female Rats.
Abstract Numerous preclinical studies demonstrate that vagus nerve stimulation (VNS) paired with motor rehabilitation improves functional recovery after neural injuries such as stroke, traumatic brain injury, and spinal cord injury, in part by driving neural plasticity within the motor cortex. To date, these studies have been performed almost exclusively in female rats, however, the risk for neural injuries of all types is significantly higher among males than females. We therefore sought to determine whether VNS was equally effective at driving motor cortical plasticity in both sexes. Male and female rats were tr...
Source: Brain Research - September 3, 2020 Category: Neurology Authors: Tseng CT, Brougher J, Gaulding SJ, Hassan BS, Thorn CA Tags: Brain Res Source Type: research

Vagus nerve stimulation enhances fear extinction as an inverted-U function of stimulation intensity
Exp Neurol. 2021 Apr 9:113718. doi: 10.1016/j.expneurol.2021.113718. Online ahead of print.ABSTRACTStudies in rodents indicate that pairing vagus nerve stimulation (VNS) with extinction training enhances fear extinction. However, the role of stimulation parameters on the effects of VNS remains largely unknown. Identifying the optimal stimulation intensity is a critical step in clinical translation of neuromodulation-based therapies. Here, we sought to investigate the role of stimulation intensity in rats receiving VNS paired with extinction training in a rat model for Posttraumatic Stress Disorder (PTSD). Male Sprague-Dawl...
Source: Experimental Neurology - April 12, 2021 Category: Neurology Authors: Rimenez R Souza Nicole M Robertson Christa K McIntyre Robert L Rennaker Seth A Hays Michael P Kilgard Source Type: research

Vagus nerve stimulation paired with rehabilitation for upper limb motor function after ischaemic stroke (VNS-REHAB): a randomised, blinded, pivotal, device trial
Publication date: 24–30 April 2021Source: The Lancet, Volume 397, Issue 10284Author(s): Jesse Dawson, Charles Y Liu, Gerard E Francisco, Steven C Cramer, Steven L Wolf, Anand Dixit, Jen Alexander, Rushna Ali, Benjamin L Brown, Wuwei Feng, Louis DeMark, Leigh R Hochberg, Steven A Kautz, Arshad Majid, Michael W O'Dell, David Pierce, Cecília N Prudente, Jessica Redgrave, Duncan L Turner, Navzer D Engineer
Source: The Lancet - April 23, 2021 Category: General Medicine Source Type: research

Vagus nerve stimulation: a potential new treatment for ischaemic stroke
Publication date: 24–30 April 2021Source: The Lancet, Volume 397, Issue 10284Author(s): Anne van der Meij, Marieke J H Wermer
Source: The Lancet - April 23, 2021 Category: General Medicine Source Type: research

Surgical procedure may help restore hand and arm function after stroke
(University of Southern California - Health Sciences) Patients who received a novel treatment that combines vagus nerve stimulation (VNS) and rehabilitation showed improvement in upper body motor impairment compared to those who received sham (inactive form of) stimulation and rehabilitation.
Source: EurekAlert! - Medicine and Health - April 26, 2021 Category: International Medicine & Public Health Source Type: news

Vagus Nerve Stimulation Paired with Rehabilitation Improves Motor Function in Stroke Patients
No abstract available
Source: Neurology Today - June 3, 2021 Category: Neurology Tags: In the Pipeline Source Type: research

Vagus nerve stimulation in ischaemic stroke: further possibilities
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Source: British Journal of Neurosurgery - July 20, 2021 Category: Neurosurgery Authors: Ashwin Kumaria Surajit Basu Christos M. Tolias Source Type: research

Brain plasticity and vagus nerve stimulation
Auton Neurosci. 2021 Sep 7;236:102876. doi: 10.1016/j.autneu.2021.102876. Online ahead of print.ABSTRACTAfter damage to the central nervous system, caused by traumatic injury or ischemia, plasticity becomes critically important for functional recovery. When this inherent capacity to adapt is limited despite training, external stimulation may support this process. Vagus nerve stimulation (VNS) is an effective method to enhance the effect of motor rehabilitation training on functional recovery. However, the mechanisms by which VNS exerts beneficial effects on cortical plasticity are not completely understood. Experimental wo...
Source: Autonomic Neuroscience - September 19, 2021 Category: Neuroscience Authors: Marius Keute Alireza Gharabaghi Source Type: research