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Specialty: Cardiology
Condition: Coronary Heart Disease

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Total 1653 results found since Jan 2013.

Hypertensive Retinopathy and Risk of Stroke Hypertensive Retinopathy
In this study, we examine whether hypertensive retinopathy predicts the long-term risk of stroke in those with hypertension. A total of 2907 participants with hypertension aged 50 to 73 years at the 1993 to 1995 examination, who had gradable retinal photographs, no history of diabetes mellitus, stroke, and coronary heart disease at baseline and data on incident stroke, were included from the Atherosclerosis Risk in Communities (ARIC) Study. Retinal photographs were assessed for hypertensive retinopathy signs and classified as none, mild, and moderate/severe. Incident events of any stroke, cerebral infarction, and hemorrhag...
Source: Hypertension - September 11, 2013 Category: Cardiology Authors: Ong, Y.-T., Wong, T. Y., Klein, R., Klein, B. E. K., Mitchell, P., Sharrett, A. R., Couper, D. J., Ikram, M. K. Tags: Cerebrovascular disease/stroke, Acute Cerebral Infarction, Risk Factors for Stroke Hypertensive Retinopathy Source Type: research

Sex Differences in the Association Between Insulin Resistance and Incident Coronary Heart Disease and Stroke Among Blacks Without Diabetes Mellitus: The Jackson Heart Study Epidemiology
ConclusionsBoth HOMA‐IR and the McAuley index demonstrate strong associations with CHD but not stroke risk in blacks. The logHOMA‐IR and CHD association was present in men, but not in women.
Source: JAHA:Journal of the American Heart Association - February 2, 2017 Category: Cardiology Authors: Effoe, V. S., Wagenknecht, L. E., Echouffo Tcheugui, J. B., Chen, H., Joseph, J. J., Kalyani, R. R., Bell, R. A., Wu, W.-C. H., Casanova, R., Bertoni, A. G. Tags: Cardiovascular Disease, Epidemiology, Risk Factors, Cerebrovascular Disease/Stroke Original Research Source Type: research

Clopidogrel Use Is Associated With an Increased Prevalence of Cerebral Microbleeds in a Stroke-Free Population: The Rotterdam Study Stroke
Conclusions In stroke-free individuals, clopidogrel use was associated with a higher prevalence and higher number of CMBs. Whether this association is causal requires confirmation in prospective studies, especially given the small number of participants taking clopidogrel and the possibility of residual confounding in this study.
Source: JAHA:Journal of the American Heart Association - September 26, 2013 Category: Cardiology Authors: Darweesh, S. K. L., Leening, M. J. G., Akoudad, S., Loth, D. W., Hofman, A., Arfan Ikram, M., Vernooij, M. W., Stricker, B. H. Tags: Stroke Source Type: research

PCSK9 Loss-of-Function Variants, Low-Density Lipoprotein Cholesterol, and Risk of Coronary Heart Disease and Stroke: Data From 9 Studies of Blacks and Whites Original Articles
Conclusions— PCSK9 LOF variants were associated with lower LDL-C and coronary heart disease incidence. PCSK9 LOF variants were not associated with stroke risk.
Source: Circulation: Cardiovascular Genetics - August 2, 2017 Category: Cardiology Authors: Kent, S. T., Rosenson, R. S., Avery, C. L., Chen, Y.-D. I., Correa, A., Cummings, S. R., Cupples, L. A., Cushman, M., Evans, D. S., Gudnason, V., Harris, T. B., Howard, G., Irvin, M. R., Judd, S. E., Jukema, J. W., Lange, L., Levitan, E. B., Li, X., Liu, Tags: Lipids and Cholesterol, Genetic, Association Studies, Myocardial Infarction, Meta Analysis, Cerebrovascular Disease/Stroke Original Articles Source Type: research

Large-Scale Phenome-Wide Association Study of PCSK9 Variants Demonstrates Protection Against Ischemic Stroke Original Articles
Conclusions: This result represents the first genetic evidence in a large cohort for the protective effect of PCSK9 inhibition on ischemic stroke and corroborates exploratory evidence from clinical trials. PCSK9 inhibition was not associated with variables other than those related to LDL (low-density lipoprotein) cholesterol, atherosclerosis, and type 2 diabetes mellitus, suggesting that other effects are either small or absent.
Source: Circulation: Cardiovascular Genetics - July 11, 2018 Category: Cardiology Authors: Rao, A. S., Lindholm, D., Rivas, M. A., Knowles, J. W., Montgomery, S. B., Ingelsson, E. Tags: Cardiovascular Disease, Diabetes, Type 2, Genetic, Association Studies, Ischemic Stroke Original Articles Source Type: research

Combined effects of hypertension and heart rate on the risk of stroke and coronary heart disease: a population-based prospective cohort study among Inner Mongolians in China
n & Yonghong Zhang
Source: Hypertension Research - December 7, 2015 Category: Cardiology Authors: Chongke ZhongXiaoyan ZhongTian XuHao PengHongmei LiMingzhi ZhangAili WangTan XuYingxian SunYonghong Zhang Tags: cohort study coronary heart disease heart rate stroke Source Type: research

Comparative mortality according to peripheral artery disease and coronary heart disease/stroke in the United States
CONCLUSIONS: In the US adults, PAD contributed to increased mortality in persons with and without CHD/stroke. The prognosis of PAD without CHD/stroke was no better than that of CHD/stroke without PAD. These results suggest the importance of recognizing the presence of PAD in the community.PMID:35584971 | DOI:10.1016/j.atherosclerosis.2022.04.029
Source: Atherosclerosis - May 18, 2022 Category: Cardiology Authors: Kunihiro Matsushita Yumin Gao Yingying Sang Shoshana H Ballew Maya Salameh Matthew Allison Elizabeth Selvin Josef Coresh Source Type: research

Lp(a) Lipoprotein(a) and Risk of Ischemic Stroke in the REGARDS Study.
Conclusions- We confirm that Lp(a) is a risk factor for ischemic stroke. Further research is needed to confirm the role of racial differences of the Lp(a) risk multiplier in ischemic stroke. PMID: 30786745 [PubMed - as supplied by publisher]
Source: Arteriosclerosis, Thrombosis and Vascular Biology - February 21, 2019 Category: Cardiology Authors: Arora P, Kalra R, Callas PW, Alexander KS, Zakai NA, Wadley V, Arora G, Kissela BM, Judd SE, Cushman M Tags: Arterioscler Thromb Vasc Biol Source Type: research

Total and specific fruit and vegetable consumption and risk of stroke: A prospective study
Conclusion: This study shows an inverse association of fruit and vegetable consumption with stroke risk. Particularly consumption of apples and pears and green leafy vegetables was inversely associated with stroke.Highlights: ► Fruit and vegetables is a heterogeneous food group with different content of nutrients. ► It remains unclear which fruit and vegetable subgroups that are most protective against stroke. ► We examined the relation between fruit and vegetable consumption and stroke risk. ► Particularly consumption of apples/pears and green leafy vegetables was inversely associated with stroke.
Source: Atherosclerosis - January 7, 2013 Category: Cardiology Authors: Susanna C. Larsson, Jarmo Virtamo, Alicja Wolk Tags: Epidemiology, Biomarkers, Nutrition Source Type: research

Identification of stroke-associated-antigens via screening of recombinant proteins from the human expression cDNA library (SEREX).
CONCLUSIONS: SEREX identified RPA2 as the antigen associated with ischemic stroke and serum auto-antibodies against RPA2 elevates in stroke patients. RPA2-Abs could become a biomarker for the evaluation of ischemic stroke at risk. PMID: 25779121 [PubMed - in process]
Source: Atherosclerosis - March 20, 2015 Category: Cardiology Authors: Machida T, Kubota M, Kobayashi E, Iwadate Y, Saeki N, Yamaura A, Nomura F, Takiguchi M, Hiwasa T Tags: J Transl Med Source Type: research

Control of main risk factors after ischaemic stroke across Europe: data from the stroke-specific module of the EUROASPIRE III survey
Conclusion The EUROASPIRE III stroke-specific module shows that secondary prevention and risk factor control in patients after ischaemic stroke need to be improved in four European centres at the time of the study since about half of patients are not achieving risk factor targets defined in European guidelines.
Source: European Journal of Preventive Cardiology - September 11, 2015 Category: Cardiology Authors: Heuschmann, P. U., Kircher, J., Nowe, T., Dittrich, R., Reiner, Z., Cifkova, R., Malojcic, B., Mayer, O., Bruthans, J., Wloch-Kopec, D., Prugger, C., Heidrich, J., Keil, U. Tags: Original scientific paper Source Type: research

Relation of Left Atrial Dysfunction to Ischemic Stroke in Patients With Coronary Heart Disease (from the Heart and Soul Study)
In conclusion, LA dysfunction is an independent risk factor for stroke or TIA, even in patients without baseline AF.
Source: The American Journal of Cardiology - March 5, 2014 Category: Cardiology Authors: Jonathan M. Wong, Christine C. Welles, Farnaz Azarbal, Mary A. Whooley, Nelson B. Schiller, Mintu P. Turakhia Tags: Arrhythmias and Conduction Disturbances Source Type: research

Thoracic aortic calcification is associated with incident stroke in the general population in addition to established risk factors
Conclusion Calcification of the thoracic aorta, more specifically its descending segment, is associated with incident stroke in addition to established risk factors. CAC outperforms aortic calcification as a stroke predictor.
Source: European Journal of Echocardiography - May 20, 2015 Category: Cardiology Authors: Hermann, D. M., Lehmann, N., Gronewold, J., Bauer, M., Mahabadi, A. A., Weimar, C., Berger, K., Moebus, S., Jockel, K.-H., Erbel, R., Kalsch, H., on behalf of the Heinz Nixdorf Recall Study Investigative Group, on behalf of the Heinz Nixdorf Recall Study Tags: ORIGINAL ARTICLES Source Type: research

Comparison of Risk Scores for the Prediction of Stroke in African Americans: Findings from the Jackson Heart Study
Conclusions Both scores were associated with incident stroke in a dose–response fashion; however, the CVD risk model was more discriminating than the CVH model. The CVH score may still be preferable for its simplicity in application to broad patient populations and public health efforts.
Source: American Heart Journal - April 16, 2016 Category: Cardiology Source Type: research

Association of Non-LDL Indices with Recurrent Stroke Risk while on Lipid-Modifying Therapy.
CONCLUSIONS: Compared with the nonuse of LT, there may be a hierarchy of residual vascular risk after stroke by non-LDL type and target, while on LT. Particularly, stroke patients with low HDL-C levels on LT may benefit from additional therapeutic strategies to improve their outcomes. PMID: 31189759 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - June 15, 2019 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research