Hypertensive Retinopathy and Risk of Stroke [Hypertensive Retinopathy]

In this study, we examine whether hypertensive retinopathy predicts the long-term risk of stroke in those with hypertension. A total of 2907 participants with hypertension aged 50 to 73 years at the 1993 to 1995 examination, who had gradable retinal photographs, no history of diabetes mellitus, stroke, and coronary heart disease at baseline and data on incident stroke, were included from the Atherosclerosis Risk in Communities (ARIC) Study. Retinal photographs were assessed for hypertensive retinopathy signs and classified as none, mild, and moderate/severe. Incident events of any stroke, cerebral infarction, and hemorrhagic stroke were identified and validated. After a mean follow-up period of 13.0 years, 165 persons developed incident stroke (146 cerebral infarctions and 15 hemorrhagic strokes). After adjusting for age, sex, blood pressure, and other risk factors, persons with moderate hypertensive retinopathy were more likely to have stroke (moderate versus no retinopathy: multivariable hazard ratios, 2.37 [95% confidence interval, 1.39–4.02]). In participants with hypertension on medication with good control of blood pressure, hypertensive retinopathy was related to an increased risk of cerebral infarction (mild retinopathy: hazard ratio, 1.96 [95% confidence interval, 1.09–3.55]; and moderate retinopathy: hazard ratio, 2.98 [95% confidence interval, 1.01–8.83]). Hypertensive retinopathy predicts the long-term risk of stroke, independent of blood pressur...
Source: Hypertension - Category: Cardiology Authors: Tags: Cerebrovascular disease/stroke, Acute Cerebral Infarction, Risk Factors for Stroke Hypertensive Retinopathy Source Type: research