Identification of stroke-associated-antigens via screening of recombinant proteins from the human expression cDNA library (SEREX).

CONCLUSIONS: SEREX identified RPA2 as the antigen associated with ischemic stroke and serum auto-antibodies against RPA2 elevates in stroke patients. RPA2-Abs could become a biomarker for the evaluation of ischemic stroke at risk. PMID: 25779121 [PubMed - in process]

http://www.ncbi.nlm.nih.gov/pubmed/25779121?dopt=Abstract

Source: Atherosclerosis - March 20, 2015 Category: Cardiology Authors: Machida T, Kubota M, Kobayashi E, Iwadate Y, Saeki N, Yamaura A, Nomura F, Takiguchi M, Hiwasa T Tags: J Transl Med Source Type: research