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Procedure: Gastroschisis Repair
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Total 4990 results found since Jan 2013.
Left Subclavian Arterial Coverage and Stroke During Thoracic Aortic Endografting: A Systematic Review
We report a systematic review of 63 studies comprising more than 3,000 patients. We conclude that stroke risk after TEVAR is increased by LSA coverage, and that LSA revascularization reduces stroke risk. LSA revascularization may lower the rate of posterior stroke. TEVAR for aneurysm is associated with increased stroke risk compared to TEVAR for dissection.
Source: The Annals of Thoracic Surgery - November 17, 2015 Category: Cardiovascular & Thoracic Surgery Source Type: research
Prefrontal Cortex Activation While Walking Under Dual-Task Conditions in Stroke: A Multimodal Imaging Study
Conclusion. Our results provide novel evidence that enhanced brain activity changes relate to dual task motor decrements.
Source: Neurorehabilitation and Neural Repair - June 2, 2016 Category: Neurology Authors: Al-Yahya, E., Johansen-Berg, H., Kischka, U., Zarei, M., Cockburn, J., Dawes, H. Tags: Clinical Research Articles Source Type: research
Robotic Quantification of Position Sense in Children With Perinatal Stroke
Conclusions. Robotic assessment of position sense is feasible in children with perinatal stroke. Impairment is common and worse in arterial lesions. Limited correction with vision suggests cortical sensory network dysfunction. Disordered position sense may represent a therapeutic target in hemiparetic cerebral palsy.
Source: Neurorehabilitation and Neural Repair - August 8, 2016 Category: Neurology Authors: Kuczynski, A. M., Dukelow, S. P., Semrau, J. A., Kirton, A. Tags: Clinical Research Articles Source Type: research
Estimated Prestroke Peak VO2 Is Related to Circulating IGF-1 Levels During Acute Stroke
Conclusions. Improving aerobic fitness prior to stroke may be beneficial by increasing baseline IGF-1 levels. These results set the groundwork for future clinical trials to determine whether high IGF-1 and aerobic fitness are beneficial to stroke recovery by providing neuroprotection and improving function.
Source: Neurorehabilitation and Neural Repair - December 10, 2016 Category: Neurology Authors: Mattlage, A. E., Rippee, M. A., Abraham, M. G., Sandt, J., Billinger, S. A. Tags: Original Research Articles Source Type: research
Diverse functions and mechanisms of pericytes in ischemic stroke.
Abstract
Pericytes are mural cells embedded in the basement membrane of microvessels. Because of such a unique position in the blood-brain barrier (BBB) and neurovascular unit (NVU), they receive, orchestrate and process signals from their neighboring cells to generate diverse neurovascular functions, including regulation of capillary hemodynamics, BBB permeability, clearance of toxic metabolites, angiogenesis, neuroinflammation and stem cell activity. During the different stages of ischemic stroke, pericytes play different roles: 1) On the hyperacute phase of stroke, pericytes constriction and death may be a caus...
Source: Current Neuropharmacology - January 11, 2017 Category: Drugs & Pharmacology Authors: Yang S, Jin H, Zhu Y, Wan Y, Zhu L, Hu B Tags: Curr Neuropharmacol Source Type: research
Multipotent Adult Progenitor Cells Enhance Recovery After Stroke by Modulating the Immune Response from the Spleen
Abstract
Stem cell therapy modulates not only the local microenvironment of the brain but also the systemic immune responses. We explored the impact of human multipotent adult progenitor cells (MAPC) modulating splenic activation and peripheral immune responses after ischemic stroke. Hundred twenty‐six Long‐Evans adult male rats underwent middle cerebral artery occlusion. Twenty‐four hours later, they received IV MAPC or saline treatment. At 3 days after infusion, RNA was isolated from the injured cortex and spleen for microarray analysis. Spleen mass, splenocyte phenotype, and releasing cytokines were measured. Seru...
Source: Stem Cells - March 5, 2017 Category: Stem Cells Authors: Bing Yang, Jason A. Hamilton, Krystal S. Valenzuela, Annelies Bogaerts, XiaoPei Xi, Jaroslaw Aronowski, Robert W. Mays, Sean I. Savitz Tags: Regenerative Medicine Source Type: research
Life interrupted and life regained? Coping with stroke at a young age.
Authors: Kuluski K, Dow C, Locock L, Lyons RF, Lasserson D
Abstract
Stroke is a leading cause of disability across the developed world, affecting an increasing number of younger people. In this article, we seek to understand the experience of stroke as a disabling life situation among young people and the strategies that they use to recover and cope. Directed content analysis was conducted from interviews with 17 community-dwelling stroke survivors aged 55 years and younger across the United Kingdom. The sample was drawn from a larger maximum variation sample of stroke survivors. Using the sociological concepts of ...
Source: International Journal of Qualitative Studies on Health and Well-being - June 2, 2017 Category: International Medicine & Public Health Tags: Int J Qual Stud Health Well-being Source Type: research
Effects of total saponins from Trillium tschonoskii rhizome on grey and white matter injury evaluated by quantitative multiparametric MRI in a rat model of ischemic stroke
Conclusion Our results suggested the potential protective and repair-promoting effects of TSTT on grey and white matter from damage induced by ischemia. This study provides a modern pharmacological basis for the application of TSTT in managing ischemic stroke. Graphical abstract
Source: Journal of Ethnopharmacology - January 12, 2018 Category: Drugs & Pharmacology Source Type: research
Effects of Xiaoshuan Enteric-Coated Capsule on White and Gray Matter Injury Evaluated by Diffusion Tensor Imaging in Ischemic Stroke.
This study was to investigate the effects of XSECC on white and gray matter injury in a rat model of ischemic stroke by diffusion tensor imaging (DTI) and histopathological analyses. The ischemia was induced by middle cerebral artery occlusion (MCAO). The cerebral blood flow measured by arterial spin labeling was improved by treatment with XSECC on the 3rd, 7th, 14th and 30th days after MCAO. Spatiotemporal white and gray matter changes in MCAO rats were examined with DTI-derived parameters (fractional anisotropy, FA; apparent diffusion coefficient, ADC; axial diffusivity, λ//; radial diffusivity, λ⊥). The increased FA...
Source: Cell Transplantation - October 4, 2018 Category: Cytology Authors: Zhang J, Chen S, Shi W, Li M, Zhan Y, Yang L, Zou H, Lei J, Chai X, Gao K, Liu J, Wang W, Wang Y, Zhao H Tags: Cell Transplant Source Type: research
The peripheral immune response after stroke-A double edge sword for blood-brain barrier integrity.
Abstract
The blood-brain barrier (BBB) is a highly regulated interface that separates the peripheral circulation and the brain. It plays a vital role in regulating the trafficking of solutes, fluid, and cells at the blood-brain interface and maintaining the homeostasis of brain microenvironment for normal neuronal activity. Growing evidence has led to the realization that ischemic stroke elicits profound immune responses in the circulation and the activation of multiple subsets of immune cells, which in turn affect both the early disruption and the later repair of the BBB after stroke. Distinct phenotypes or subse...
Source: CNS Neuroscience and Therapeutics - November 1, 2018 Category: Neuroscience Authors: Li Y, Zhu ZY, Huang TT, Zhou YX, Wang X, Yang LQ, Chen ZA, Yu WF, Li PY Tags: CNS Neurosci Ther Source Type: research
Post-stroke inflammation —target or tool for therapy?
AbstractInflammation is currently considered a prime target for the development of new stroke therapies. In the acute phase of ischemic stroke, microglia are activated and then circulating immune cells invade the peri-infarct and infarct core. Resident and infiltrating cells together orchestrate the post-stroke inflammatory response, communicating with each other and the ischemic neurons, through soluble and membrane-bound signaling molecules, including cytokines. Inflammation can be both detrimental and beneficial at particular stages after a stroke. While it can contribute to expansion of the infarct, it is also responsi...
Source: Acta Neuropathologica - November 27, 2018 Category: Neurology Source Type: research
Human stem cells transplanted into the rat stroke brain migrate to spleen via lymphatic and inflammation pathways.
This study is the first to demonstrate brain-to-periphery migration of stem cells, advancing the novel concept of harnessing the lymphatic system in mobilizing stem cells to sequester peripheral inflammation as a brain repair strategy.
PMID: 30514806 [PubMed - as supplied by publisher]
Source: Haematologica - December 4, 2018 Category: Hematology Authors: Xu K, Lee JY, Kaneko Y, Tuazon JP, Vale F, van Loveren H, Borlongan CV Tags: Haematologica Source Type: research
CCR5 Is a Therapeutic Target for Recovery after Stroke and Traumatic Brain Injury
Publication date: 21 February 2019Source: Cell, Volume 176, Issue 5Author(s): Mary T. Joy, Einor Ben Assayag, Dalia Shabashov-Stone, Sigal Liraz-Zaltsman, Jose Mazzitelli, Marcela Arenas, Nora Abduljawad, Efrat Kliper, Amos D. Korczyn, Nikita S. Thareja, Efrat L. Kesner, Miou Zhou, Shan Huang, Tawnie K. Silva, Noomi Katz, Natan M. Bornstein, Alcino J. Silva, Esther Shohami, S. Thomas CarmichaelSummaryWe tested a newly described molecular memory system, CCR5 signaling, for its role in recovery after stroke and traumatic brain injury (TBI). CCR5 is uniquely expressed in cortical neurons after stroke. Post-stroke neuronal kno...
Source: Cell - February 22, 2019 Category: Cytology Source Type: research
Toll-Like Receptor 4 Regulates Subventricular Zone Proliferation and Neuroblast Migration after Experimental Stroke
Publication date: Available online 3 May 2019Source: Brain, Behavior, and ImmunityAuthor(s): Sara Palma-Tortosa, Olivia Hurtado, Jesús Miguel Pradillo, Raquel Ferreras-Martín, Isaac García-Yébenes, Alicia García-Culebras, Ana Moraga, María Ángeles Moro, Ignacio LizasoainAbstractIschemic stroke is one of the leading causes of death and disability with an urgent need for innovative therapies, especially targeting the chronic phase. New evidence has emerged showing that Toll-Like Receptor 4 (TLR4), a key mediator of brain damage after stroke, may be involved in brain repair by neurogenesis modulation. The aim of this s...
Source: Brain, Behavior, and Immunity - May 3, 2019 Category: Neurology Source Type: research
Cyclic nucleotide phosphodiesterases (PDEs) and endothelial function in ischaemic stroke. A review.
CONCLUSION: This review demonstrates that non-selective and selective PDEi of PDE3, PDE4 and PDE5 modulated endothelial function in cerebral ischemic stroke by regulating processes involved in vascular repair and neuroprotection and thus reduced cell death and inflammation. Of note, they promoted angiogenesis, microcirculation and improved functional recovery; all are important in stroke prevention and recovery, and effects should be further evaluated in humans.
PMID: 31132399 [PubMed - as supplied by publisher]
Source: Cellular Signalling - May 23, 2019 Category: Cytology Authors: Yasmeen S, Akram BH, Hainsworth AH, Kruuse C Tags: Cell Signal Source Type: research
