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Total 394 results found since Jan 2013.

How do patients with Type 2 Diabetes Mellitus value the importance of outcomes? An overview of reviews
CONCLUSION: We provide standardised, reliable utility values (or associated disutilities) for T2DM, acute, microvascular and macrovascular complications, related comorbidities and treatments that may support judgements when making clinical recommendations, designing decision support tools, and developing interventions and economic analysis.PMID:37516195 | DOI:10.1016/j.jval.2023.07.003
Source: Cancer Control - July 29, 2023 Category: Cancer & Oncology Authors: Ena Nino-de-Guzman Javier Bracchiglione Adrian Vasquez-Mejia Gimon de Graaf Claudio Rocha Calderon Pablo Alonso-Coello Source Type: research

Methemoglobin as a marker of acute anemic stress in cardiac surgery
iScience. 2023 Jul 20;26(8):107429. doi: 10.1016/j.isci.2023.107429. eCollection 2023 Aug 18.ABSTRACTBiological evidence supports plasma methemoglobin as a biomarker for anemia-induced tissue hypoxia. In this translational planned substudy of the multinational randomized controlled transfusion thresholds in cardiac surgery (TRICS-III) trial, which included adults undergoing cardiac surgery requiring cardiopulmonary bypass with a moderate-to-high risk of death, we investigated the relationship between perioperative hemoglobin concentration (Hb) and methemoglobin; and evaluated its association with postoperative outcomes. Th...
Source: Pain Physician - August 14, 2023 Category: Anesthesiology Authors: Nikhil Mistry Gregory M T Hare Nadine Shehata Robert S Kramer Hosam F Fawzy Robert A Baker Paula Carmona Richard Saczkowski Daniela Filipescu Christella S Alphonsus Antoine Rochon Alexander J Gregory Boris Khanykin Jonathan D Leff Eva Mateo Dimos Karangel Source Type: research

Signal detection of adverse events associated with gabapentinoid use for chronic pain
CONCLUSIONS: Our study identified expected and unexpected ADE signals in GABA users. Neurological signals likely related to indications for GABA use. Signals for immunity, mental/behavior, and skin disorders were found in the FDA adverse event reporting system database. Unexpected signals of stroke and cancer require further confirmatory analyses to verify.PMID:37640024 | DOI:10.1002/pds.5685
Source: Cancer Control - August 28, 2023 Category: Cancer & Oncology Authors: Yong-Fang Kuo Efstathia Polychronopoulou Mukaila A Raji Source Type: research

Acute Aortic Emergencies—Part 2 Aortic Dissections
Patients with aortic disease are some of the highest acuity patients that emergency clinicians encounter. Dissection is the most common aortic catastrophe and involves separation of the aortic layers in a longitudinal fashion leading to diminished perfusion and systemic ischemia. Characteristics of pain, branch vessel involvement, and incidence lead to an understanding of patient presentation, morbidity, and mortality. Diagnosis, selection of diagnostic studies, the degree of preoperative ischemia, and risk of operative mortality can be accomplished using validated clinical decision tools. Emergency interventions are guide...
Source: Advanced Emergency Nursing Journal - January 1, 2013 Category: Emergency Medicine Tags: Cases of Note Source Type: research

Medical management of critical limb ischaemia: where do we stand today?
This article is protected by copyright. All rights reserved.
Source: Journal of Internal Medicine - June 26, 2013 Category: Internal Medicine Authors: Matthew A. Lambert, Jill J. F. Belch Tags: Review Source Type: research

157 E-Books New to JEFFLINE
Scott Library added these 157 e-books to the growing collection in May and June: Accurate Results in the Clinical Laboratory Adult Emergency Medicine Adult-Gerontology and Family Nurse Practitioner Certification Examination (4th ed.) Advanced Assessment: Interpreting Findings and Formulating Differential Diagnoses (2nd ed.) Advancing Your Career: Concepts of Professional Nursing (5th ed.) Arrhythmia Essentials Atlas of Advanced Operative Surgery Atlas of Clinical Neurology (3rd ed.) Atlas of Hematopathology: Morphology, Immunophenotype, Cytogenetics, and Molecular Approaches Atlas of Human Infectious Diseases Atlas of No...
Source: What's New on JEFFLINE - June 25, 2013 Category: Databases & Libraries Authors: Gary Kaplan Tags: All News Clinicians Researchers Students Teaching Faculty Source Type: news

Why acupuncture is giving sceptics the needle
Acupuncture has been prescribed by half of Britain's doctors, but after 3,000 clinical trials its efficacy remains unproven. So is the NHS making a grave error in supporting this ancient treatment?• Are vitamin pills a sham? Q&A with Dr. Paul OffitYou can't get crystal healing on the NHS. The Department of Health doesn't fund faith healing. And most doctors believe magnets are best stuck on fridges, not patients. But ask for a treatment in which an expert examines your tongue, smells your skin and tries to unblock the flow of life force running through your body with needles and the NHS will be happy to oblige.The govern...
Source: Guardian Unlimited Science - July 26, 2013 Category: Science Authors: David Derbyshire Tags: Culture Health Science and scepticism Features NHS Alternative medicine The Observer Source Type: news

Pharmacologic Reperfusion Therapy with Indigenous Tenecteplase in 15,222 patients with ST Elevation Myocardial Infarction - The Indian Registry.
CONCLUSION: This study confirms the safety and efficacy of indigenous tenecteplase in Indian patients with STEMI, including high risk subgroups. It also highlights the fact that delayed treatment denotes denial of benefits of pharmacologic reperfusion therapy. PMID: 23993004 [PubMed - in process]
Source: Indian Heart J - July 1, 2013 Category: Cardiology Authors: Iyengar SS, Nair T, Hiremath JS, Jadhav U, Katyal VK, Kumbla D, Sathyamurthy I, Jain RK, Srinivasan M Tags: Indian Heart J Source Type: research

Asthma Management in Sickle Cell Disease.
Abstract Asthma is a common comorbid factor in sickle cell disease (SCD). However, the incidence of asthma in SCD is much higher than expected compared to rates in the general population. Whether "asthma" in SCD is purely related to genetic and environmental factors or rather is the consequence of the underlying hemolytic and inflammatory state is a topic of recent debate. Regardless of the etiology, hypoxemia induced by bronchoconstriction and inflammation associated with asthma exacerbations will contribute to a cycle of sickling and subsequent complications of SCD. Recent studies confirm that asthma predisposes...
Source: Biomed Res - December 14, 2013 Category: Research Authors: Gomez E, Morris CR Tags: Biomed Res Int Source Type: research

Five-year results for endovascular repair of acute complicated type B aortic dissection
Conclusions: This study confirms the excellent short-term outcomes of TEVAR for acute complicated type B dissection and demonstrates the results to be durable and sustained over long-term follow-up. Although aortic reinterventions were required in one-quarter of patients, no aortic-related deaths were observed. These data support the use of TEVAR for acute complicated type B aortic dissection but also highlight the importance of life-long aortic surveillance by an experienced aortic referral center in order to identify and treat complications of the underlying disease process and treatment, as well as new aortic pathologies, as they arise.
Source: Journal of Vascular Surgery - October 3, 2013 Category: Surgery Authors: Jennifer M. Hanna, Nicholas D. Andersen, Asvin M. Ganapathi, Richard L. McCann, G. Chad Hughes Tags: Clinical research studies Source Type: research

Comparison of In-Hospital Outcomes for Beta-Blocker Use Versus Non–Beta Blocker Use in Patients Presenting With Cocaine-Associated Chest Pain
In conclusion, no differences in outcomes were observed between patients treated versus not treated with β-blocker therapy in the setting of cocaine-related chest pain.
Source: The American Journal of Cardiology - March 17, 2014 Category: Cardiology Authors: Zaher Fanari, Kevin K. Kennedy, Michael J. Lim, Abhay A. Laddu, Joshua M. Stolker Tags: Coronary Artery Disease Source Type: research

Laughter Is Serious Business!
Knock, knock! Who’s there? Theodore! Theodore who? Theodore is stuck and it won’t open! Q: Why do bicycles fall over? A: Because they are two-tired! Q: What did one snowman say to the other snowman? A: Do you smell carrots? But seriously, folks — laughing is no laughing matter. If you want to be healthy; if you want to be positively connected to others; if you want to be happy, you gotta laugh, laugh, laugh. Why? Because: Laughing is an antidote to depression, anxiety and tension. People who are able to see the humor in things generally have more optimism, more hope for the future, and less angst about t...
Source: Psych Central - June 13, 2014 Category: Psychiatry Authors: Marie Hartwell-Walker, Ed.D. Tags: Anxiety Depression Disorders General Happiness Self-Help cortisol epinephrine Facebook jokes laughing Laughter Optimism Spontaneity Stress Management Source Type: news

Levetiracetam for neuropathic pain in adults.
CONCLUSIONS: The amount of evidence for levetiracetam in neuropathic pain conditions was very small and potentially biased because of the methods of analysis used in the studies. There was no indication that levetiracetam was effective in reducing neuropathic pain, but it was associated with an increase in participants who experienced adverse events and who withdrew due to adverse events. PMID: 25000215 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - July 7, 2014 Category: Journals (General) Authors: Wiffen PJ, Derry S, Moore RA, Lunn MP Tags: Cochrane Database Syst Rev Source Type: research

Low failure rate reported of diagnosis algorithm for suspected upper extremity deep vein thrombosis
Commentary on: Kleinjan A, Di Nisio M, Beyer-Westendorf J, et al.. Safety and feasibility of a diagnostic algorithm combining clinical probability, d-dimer testing and ultrasonography for suspected upper extremity deep venous thrombosis: a prospective management study. Ann Intern Med 2014;160:451–7. Context Upper extremity deep vein thrombosis (UEDVT) is an infrequent type of venous thromboembolism with an estimated incidence of 0.4–1 case per 10 000 persons.1 UEDVT may cause pulmonary embolism but this risk is lower than with lower extremity DVT. Accurate ruling out of UEDVT is mandatory in order to avert...
Source: Evidence-Based Medicine - September 15, 2014 Category: Internal Medicine Authors: Delluc, A., Wells, P. S. Tags: EBM Diagnosis, Drugs: cardiovascular system, Pain (neurology), Stroke, Venous thromboembolism, Radiology, Pulmonary embolism, Clinical diagnostic tests, Radiology (diagnostics) Source Type: research

The effectiveness of surgery for adults with hallux valgus deformity: partial results of quantitative systematic review.
Conclusion: Data collection and synthesis, along with assessment of methodological quality will be undertaken using JBI MAStARI software. International Journal of Evidence-Based Healthcare (C) 2014 The Joanna Briggs Institute
Source: International Journal of Evidence-Based Healthcare - September 1, 2014 Category: Nursing Tags: Abstracts of Oral Presentations: Evidence Synthesis: PDF Only Source Type: research