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Mediterranean diet: The role of long-chain ω-3 fatty acids in fish; polyphenols in fruits, vegetables, cereals, coffee, tea, cacao and wine; probiotics and vitamins in prevention of stroke, age-related cognitive decline, and Alzheimer disease.
Authors: Román GC, Jackson RE, Gadhia R, Román AN, Reis J
Abstract
The mechanisms of action of the dietary components of the Mediterranean diet are reviewed in prevention of cardiovascular disease, stroke, age-associated cognitive decline and Alzheimer disease. A companion article provides a comprehensive review of extra-virgin olive oil. The benefits of consumption of long-chain ω-3 fatty acids are described. Fresh fish provides eicosapentaenoic acid while α-linolenic acid is found in canola and soybean oils, purslane and nuts. These ω-3 fatty acids interact metabolically with ω-6 fatty acids mainly linoleic...
Source: Revue Neurologique - September 16, 2019 Category: Neurology Tags: Rev Neurol (Paris) Source Type: research
MALAT1 Activates the P53 Signaling Pathway by Regulating MDM2 to Promote Ischemic Stroke
Conclusion: These results indicate that MALAT1/MDM2/p53 signaling pathway axis may provide more effective clinical therapeutic strategy for patients with ischemic stroke.Cell Physiol Biochem 2018;50:2216 –2228
Source: Cellular Physiology and Biochemistry - November 12, 2018 Category: Cytology Source Type: research
Discovery of anti-stroke active substances in Guhong injection based on multi-phenotypic screening of zebrafish
Biomed Pharmacother. 2022 Sep 23;155:113744. doi: 10.1016/j.biopha.2022.113744. Online ahead of print.ABSTRACTIschemic stroke is a leading cause of death worldwide, and it remains an urgent task to develop novel and alternative therapeutic strategies for the disease. We previously reported the positive effects of Guhong injection (GHI), composed of safflower extract and aceglutamide, in promoting functional recovery in ischemic stroke mice. However, the active substances and pharmacological mechanism of GHI is still elusive. Aiming to identify the active anti-stroke components in GHI, here we conducted a multi-phenotypic s...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 26, 2022 Category: Drugs & Pharmacology Authors: Yule Wang Huimin Wu Hongda Sheng Yingchao Wang Xuecai Li Yi Wang Lu Zhao Source Type: research
A hydrodynamically active flipper-stroke in humpback whales.
Abstract
A central paradigm of aquatic locomotion is that cetaceans use fluke strokes to power their swimming while relying on lift and torque generated by the flippers to perform maneuvers such as rolls, pitch changes and turns [1]. Compared to other cetaceans, humpback whales (Megaptera novaeangliae) have disproportionately large flippers with added structural features to aid in hydrodynamic performance [2,3]. Humpbacks use acrobatic lunging maneuvers to attack dense aggregations of krill or small fish, and their large flippers are thought to increase their maneuverability and thus their ability to capture prey....
Source: Current Biology - July 10, 2017 Category: Biology Authors: Segre PS, Seakamela SM, Meÿer MA, Findlay KP, Goldbogen JA Tags: Curr Biol Source Type: research
Fish consumption and risk of stroke, coronary heart disease, and cardiovascular mortality in a Dutch population with low fish intake
Fish consumption and risk of stroke, coronary heart disease, and cardiovascular mortality in a Dutch population with low fish intake, Published online: 22 May 2018; doi:10.1038/s41430-018-0190-2Fish consumption and risk of stroke, coronary heart disease, and cardiovascular mortality in a Dutch population with low fish intake
Source: European Journal of Clinical Nutrition - May 22, 2018 Category: Nutrition Authors: L. M. Hengeveld J. Praagman J. W. J. Beulens I. A. Brouwer Y. T. van der Schouw I. Sluijs Source Type: research
New Cochrane health evidence challenges belief that omega 3 supplements reduce risk of heart disease, stroke or death
New evidence published today shows there is little or no effect of omega 3 supplements on our risk of experiencing heart disease, stroke or death.Omega 3 is a type of fat. Small amounts of omega 3 fats are essential for good health, and they can be found in the food that we eat. The main types of omega 3 fatty acids are; alpha linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA). ALA is normally found in fats from plant foods, such as nuts and seeds (walnuts and rapeseed are rich sources). EPA and DHA, collectively called long chain omega 3 fats, are naturally found in fatty fish, such as s...
Source: Cochrane News and Events - July 16, 2018 Category: Information Technology Authors: Muriah Umoquit Source Type: news
Mediterranean-style diet may lower women's stroke risk
(University of East Anglia) Following a Mediterranean-style diet may reduce stroke risk in women over 40 but not in men -- according to new research led by the University of East Anglia.A new report, published today in the American Heart Association's journal Stroke, reveals that a diet high in fish, fruit, vegetables, nuts and beans, and lower in meat and dairy, reduces stroke risk among white adults who are at high risk of cardiovascular disease.
Source: EurekAlert! - Biology - September 20, 2018 Category: Biology Source Type: news
Prescription Doses of Fish Oil May Lower Heart Attack and Stroke Risk
Omega-3 fatty acids, abundant in fish oil, are known to be good for the heart. Studies have shown that people who eat more fish rich in these fats have lower rates of heart problems and less risk of dying from heart disease compared to those who eat less. Those data have fueled a booming business in over-the-counter fish oil supplements.
In a new study published in the New England Journal of Medicine, and presented at the American Heart Association annual meeting, researchers report that a highly purified version of omega-3 fats, called icosapent ethyl, can lower the risk of a number of heart-related events, including hear...
Source: TIME: Health - November 10, 2018 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized healthytime Heart Disease omega-3 Source Type: news
P42 Age and Education are Associated with Fried Fish Consumption in the Stroke Belt
Fish contain polyunsaturated fatty acids which are associated with decreased cardiovascular (CVD) risk. However, frying fish alters the fatty acids. Consumption of fried fish has been linked to increased risk of CVD and stroke, particularly in populations in the South's Stroke Belt. The purpose of this study was to explore characteristics associated with fried vs. non-fried fish consumption in the rural Appalachian region of the Stroke Belt.
Source: Journal of Nutrition Education and Behavior - June 30, 2019 Category: Nutrition Authors: Frances Hardin-Fanning, Cheryl Witt, Hunter Threadgill Tags: Nutrition Across the Life Cycle Source Type: research
A Case-Based Discussion on the Management of Cryptogenic Stroke and Patent Foramen Ovale in the Patient With a Hypercoagulable Disorder
UP TO 40% of all ischemic strokes are considered cryptogenic, implying a stroke without a definitive etiology.1,2 With a dearth of evidence-guided treatment strategies, the literature surrounding cryptogenic stroke is highly variable and not well-standardized. Even though existing guidelines do not specify the exact testing required, the cryptogenic stroke evaluation includes a variety of imaging modalities (eg, echocardiography, angiography, magnetic resonance imaging, carotid ultrasound) and laboratory investigations (eg, genetic testing, hypercoagulable disorder panels, erythrocyte sedimentation rate).
Source: Journal of Cardiothoracic and Vascular Anesthesia - August 27, 2019 Category: Anesthesiology Authors: Neal S. Gerstein, Stacey D. Clegg, Daniel B. Levin, Adam C. Fish, Kirsten Tolstrup, Koki Nakanishi, Yuriko Yoshida, Shunichi Homma Tags: Case Conference Source Type: research
Will Certain Foods Bolster Brain Health After Stroke?
THURSDAY, Jan. 25, 2018 -- Stroke survivors who eat plenty of leafy greens, fish and other healthy foods may help preserve their brain function as time goes on, a preliminary study suggests.
Researchers found the benefits among stroke survivors who...
Source: Drugs.com - Daily MedNews - January 25, 2018 Category: General Medicine Source Type: news
Studies: Low-Dose Aspirin May Not Prevent Initial Heart Attack, Stroke
Taking a low-dose aspirin every day has long been known to cut the chances of another heart attack, stroke or other heart problem in people who already have had one, but the risks don’t outweigh the benefits for most other folks, major new research finds.
Although it’s been used for more than a century, aspirin’s value in many situations is still unclear. The latest studies are some of the largest and longest to test this pennies-a-day blood thinner in people who don’t yet have heart disease or a blood vessel-related problem.
One found that aspirin did not help prevent first strokes or heart attacks...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - August 27, 2018 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Healthwatch aspirin Source Type: news
Fish Oil, Particularly EPA, Linked to Reduced Ischemic Stroke Fish Oil, Particularly EPA, Linked to Reduced Ischemic Stroke
A new study of fish oils and ischemic stroke that included data on adipose tissue levels of key fatty acids has suggested a greater benefit with dietary intakes of EPA than with DHA or total fish oil.Medscape Medical News
Source: Medscape Pathology Headlines - January 17, 2019 Category: Pathology Tags: Neurology & Neurosurgery News Source Type: news
Omega-3 Supplement Use, Fish Intake, and Risk of Non-fatal Coronary Artery Disease and Ischemic Stroke in the Million Veteran Program
Observational and clinical trial evidence suggests an inverse association of omega-3 polyunsaturated fatty acid with coronary artery disease (CAD) mortality, although relationships with non-fatal CAD and stroke are less clear. We investigated whether omega-3 fatty acid supplement use and fish intake were associated with incident non-fatal CAD and ischemic stroke among US Veterans.
Source: Clinical Nutrition - March 12, 2019 Category: Nutrition Authors: Rachel E. Ward, Kelly Cho, Xuan-Mai T. Nguyen, Jason L. Vassy, Yuk-Lam Ho, Rachel M. Quaden, David R. Gagnon, Peter W.F. Wilson, J. Michael Gaziano, Luc Djouss é, VA Million Veteran Program Tags: Original article Source Type: research
