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Total 123 results found since Jan 2013.
Brain age prediction in stroke patients: Highly reliable but limited sensitivity to cognitive performance and response to cognitive training
Publication date: Available online 30 December 2019Source: NeuroImage: ClinicalAuthor(s): Geneviève Richard, Knut Kolskår, Kristine M. Ulrichsen, Tobias Kaufmann, Dag Alnæs, Anne-Marthe Sanders, Erlend S. Dørum, Jennifer Monereo Sánchez, Anders Petersen, Hege Ihle-Hansen, Jan Egil Nordvik, Lars T. WestlyeAbstractCognitive deficits are important predictors for outcome, independence and quality of life after stroke, but often remain unnoticed and unattended because other impairments are more evident. Computerized cognitive training (CCT) is among the candidate interventions that may alleviate cognitive difficulties, but...
Source: NeuroImage: Clinical - December 30, 2019 Category: Radiology Source Type: research
Enhanced white matter reorganization and activated brain glucose metabolism by enriched environment following ischemic stroke: Micro PET/CT and MRI study.
This study aimed to examine the effects of post-ischemic EE treatment on the brain remodeling using magnetic resonance imaging (MRI) and 18F-FDG positron emission tomography (PET). Male Sprague-Dawley rats were subjected to permanent middle cerebral artery occlusion (MCAO) and housed in standard environment (SE) or EE for consecutive 30 days. Cognitive testing was performed using the Morris water maze. White matter structural modifications were detected by MRI combined with histological analysis. In addition, PET scanning with 18F-FDG as a molecular probe was conducted to detect brain energy metabolism. Our results showed ...
Source: Neuropharmacology - June 28, 2020 Category: Drugs & Pharmacology Authors: Li M, Zhao Y, Zhan Y, Yang L, Feng X, Lu Y, Lei J, Zhao T, Wang L, Zhao H Tags: Neuropharmacology Source Type: research
DWI Negative Stroke: Learning Points For Imaging In Acute Stroke (P1.037)
CONCLUSIONS: Clinical exam bears more weight than imaging in suspected brainstem infarcts. With the increasing use of DWI as the imaging of choice in acute stroke, DWI negative stroke must be considered in patients who present with classic brain stem infarcts with negative imaging to prevent delay in therapy as these patients may still be a candidate for thrombolysis.Disclosure: Dr. Nalleballe has nothing to disclose. Dr. JADEJA has nothing to disclose. Dr. Bollu has nothing to disclose. Dr. Onteddu has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Nalleballe, K., Jadeja, N., Bollu, P., Onteddu, S. Tags: Cerebrovascular Disease and Interventional Neurology: Case Reports Source Type: research
Relevance of the cerebral collateral circulation in ischaemic stroke: time is brain, but collaterals set the pace.
Abstract
Blood supply to the brain is secured by an extensive collateral circulation system, which can be divided into primary routes, i.e., the Circle of Willis, and secondary routes, e.g., collaterals from the external to the internal carotid artery and leptomeningeal collaterals. Collateral flow is the basis for acute stroke treatment, since neurones will only survive long enough to be rescued with reperfusion therapies if there is sufficient collateral flow. Poor collateral flow is associated with worse outcome and faster growth of larger infarcts in acute stroke treatment. Therapeutic promotion of collateral ...
Source: Swiss Medical Weekly - December 12, 2017 Category: General Medicine Authors: Jung S, Wiest R, Gralla J, McKinley R, Mattle H, Liebeskind D Tags: Swiss Med Wkly Source Type: research
Functional connectivity of the retrosplenial cortex in rats with ischemic stroke is improved by electroacupuncture.
CONCLUSION: These findings suggest that EA at GV20 and GV24 might improve the learning and memory ability of MICD rats by increasing the functional connectivity between the RSC and hippocampus, cingulate gyrus and midbrain, which is encouraging for the potential treatment for cognitive impairment secondary to ischemia stroke.
PMID: 32529883 [PubMed - as supplied by publisher]
Source: Acupuncture in Medicine : journal of the British Medical Acupuncture Society - June 11, 2020 Category: Complementary Medicine Authors: Zhang Q, Li J, Huang S, Yang M, Liang S, Liu W, Chen L, Tao J Tags: Acupunct Med Source Type: research
Deep Learning-Based Acute Ischemic Stroke Lesion Segmentation Method on Multimodal MR Images Using a Few Fully Labeled Subjects.
Authors: Zhao B, Liu Z, Liu G, Cao C, Jin S, Wu H, Ding S
Abstract
Acute ischemic stroke (AIS) has been a common threat to human health and may lead to severe outcomes without proper and prompt treatment. To precisely diagnose AIS, it is of paramount importance to quantitatively evaluate the AIS lesions. By adopting a convolutional neural network (CNN), many automatic methods for ischemic stroke lesion segmentation on magnetic resonance imaging (MRI) have been proposed. However, most CNN-based methods should be trained on a large amount of fully labeled subjects, and the label annotation is a labor-intensive and ti...
Source: Computational and Mathematical Methods in Medicine - February 12, 2021 Category: Statistics Tags: Comput Math Methods Med Source Type: research
Therapeutic Effect of Repetitive Transcranial Magnetic Stimulation for Post-stroke Vascular Cognitive Impairment: A Prospective Pilot Study
ConclusionsHigh-frequency rTMS on the ipsilesional DLPFC may exert immediate efficacy on cognition with the anti-inflammatory response and changes in brain network in PSCI, lasting at least 3 months.
Source: Frontiers in Neurology - March 22, 2022 Category: Neurology Source Type: research
Machine Learning-Based Model for Prediction of Hemorrhage Transformation in Acute Ischemic Stroke After Alteplase
In this study, an RF machine learning method was successfully established to predict HT in AIS patients after intravenous alteplase, which the sensitivity was 66.7%, and the specificity was 80.7%.
Source: Frontiers in Neurology - June 10, 2022 Category: Neurology Source Type: research
The Relationship between Altered Degree Centrality and Cognitive Function in Mild Subcortical Stroke: A Resting-State fMRI Study
CONCLUSIONS: DC values were increased in the right PhG following a mild subcortical stroke. DC values in the PhG were negatively correlated with cognitive function, which may indicate brain nodes reorganization.PMID:36265670 | DOI:10.1016/j.brainres.2022.148125
Source: Brain Research - October 20, 2022 Category: Neurology Authors: Yan Min Chang Liu Lijun Zuo Yongjun Wang Zixiao Li Source Type: research
Stroke risk study based on deep learning-based magnetic resonance imaging carotid plaque automatic segmentation algorithm
CONCLUSION: The evaluations in this work have demonstrated that this methodology produces acceptable results for classifying magnetic resonance imaging (MRI) data.PMID:36910524 | PMC:PMC9998982 | DOI:10.3389/fcvm.2023.1101765
Source: Atherosclerosis - March 13, 2023 Category: Cardiology Authors: Ya-Fang Chen Zhen-Jie Chen You-Yu Lin Zhi-Qiang Lin Chun-Nuan Chen Mei-Li Yang Jin-Yin Zhang Yuan-Zhe Li Yi Wang Yin-Hui Huang Source Type: research
GABA Levels Are Decreased After Stroke and GABA Changes During Rehabilitation Correlate With Motor Improvement
Conclusions. In patients 3 to 12 months poststroke, GABA levels are lower in the primary motor cortex than in healthy subjects. The observed association between GABA and recovery warrants further studies on the potential use of GABA MRS as a biomarker in poststroke recovery.
Source: Neurorehabilitation and Neural Repair - January 30, 2015 Category: Neurology Authors: Blicher, J. U., Near, J., Naess-Schmidt, E., Stagg, C. J., Johansen-Berg, H., Nielsen, J. F., Ostergaard, L., Ho, Y.-C. L. Tags: Clinical Research Articles Source Type: research
Brain mapping for long-term recovery of gait after supratentorial stroke: A retrospective cross-sectional study
The recovery of independent gait after stroke is a main goal of patients and understanding the relationship between brain lesions and the recovery of gait can help physicians set viable rehabilitation plans. Our study investigated the association between variables of gait parameters and brain lesions.
Fifty poststroke patients with a mean age of 67.5 ± 1.3 years and an average duration after onset of 62.2 ± 7.9 months were included. Three-dimensional gait analysis and magnetic resonance imaging were conducted for all patients. Twelve quantified gait parameters of temporal-spatial, kinematic, and kinetic data wer...
Source: Medicine - April 1, 2018 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
Prediction of Hemorrhagic Transformation Severity in Acute Stroke From Source Perfusion MRI
Conclusion: The key contribution of our framework formalize HT prediction as a machine learning problem. Specifically, the model learns to extract imaging markers of HT directly from source PWI images rather than from pre-established metrics. Significance: Predictions visualized in terms of spatial likelihood of HT in various territories of the brain were evaluated against follow-up gradient recalled echo and provide novel insights for neurointerventionalists prior to endovascular therapy.
Source: IEEE Transactions on Biomedical Engineering - August 21, 2018 Category: Biomedical Engineering Source Type: research
Functional Connectivity Changes in Multiple-Frequency Bands in Acute Basal Ganglia Ischemic Stroke Patients: A Machine Learning Approach
CONCLUSION: Acute BGIS patients had frequency-specific alterations in FC; SVM is a promising method for exploring these frequency-dependent FC alterations. The abnormal brain regions might be potential targets for future researchers in the rehabilitation and treatment of stroke patients.PMID:35356364 | PMC:PMC8958111 | DOI:10.1155/2022/1560748
Source: Neural Plasticity - March 31, 2022 Category: Neurology Authors: Jie Li Lulu Cheng Shijian Chen Jian Zhang Dongqiang Liu Zhijian Liang Huayun Li Source Type: research
