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Condition: Hemorrhagic Stroke
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Total 196 results found since Jan 2013.
Clustering and prediction of long-term functional recovery patterns in first-time stroke patients
ConclusionsThe longitudinal, multi-dimensional, functional assessment data of first-time stroke patients were successfully clustered, and the prediction models showed relatively good accuracies. Early identification and prediction of long-term functional outcomes will help clinicians develop customized treatment strategies.
Source: Frontiers in Neurology - March 8, 2023 Category: Neurology Source Type: research
MRI for all: Cheap portable scanners aim to revolutionize medical imaging
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The patient, a man in his 70s with a shock of silver hair, lies in the neuro intensive care unit (neuro ICU) at Yale New Haven Hospital. Looking at him, you’d never know that a few days earlier a tumor was removed from his pituitary gland. The operation didn’t leave a mark because, as is standard, surgeons reached the tumor through his nose. He chats cheerfully with a pair of research associates who have come to check his progress with a new and potentially revolutionary device they are testing.
The cylind...
Source: Science of Aging Knowledge Environment - February 23, 2023 Category: Geriatrics Source Type: research
Alpha-Asarone Ameliorates Neurological Dysfunction of Subarachnoid Hemorrhagic Rats in Both Acute and Recovery Phases via Regulating the CaMKII-Dependent Pathways
AbstractEarly brain injury (EBI) is the leading cause of poor prognosis for patients suffering from subarachnoid hemorrhage (SAH), particularly learning and memory deficits in the repair phase. A recent report has involved calcium/calmodulin-dependent protein kinase II (CaMKII) in the pathophysiological process underlying SAH-induced EBI. Alpha-asarone (ASA), a major compound isolated from the Chinese medicinal herbAcorus tatarinowii Schott, was proven to reduce secondary brain injury by decreasing CaMKII over-phosphorylation in rats ’ model of intracerebral hemorrhage in our previous report. However, the effect of ASA o...
Source: Translational Stroke Research - February 13, 2023 Category: Neurology Source Type: research
Magnetic Targeting Nanocarriers Combined with Focusing Ultrasound for Enhanced Intracerebral Hemorrhage Therapy
A magnetic targeting nanocarrier loaded with a peroxisome proliferator-activated receptor gamma agonist (15d-PGJ2-MNPs) is magnetically targeted to the area of the hematoma with the subsequent application of focusing ultrasound for alleviating brain injury, accelerating hematoma clearance, attenuating neuroinflammation, and reducing the brain edema in the intracerebral hemorrhage mouse model. AbstractIntracerebral hemorrhage (ICH) remains a significant cause of morbidity and mortality around the world, and surgery is still the most direct and effective way to remove ICH. However, the potential risks brought by surgery, suc...
Source: Small - January 27, 2023 Category: Nanotechnology Authors: Tianyi Wang,
Huali Lei,
Xiang Li,
Nailin Yang,
Cheng Ma,
Guangqiang Li,
Xiang Gao,
Jun Ge,
Zhuang Liu,
Liang Cheng,
Gang Chen Tags: Research Article Source Type: research
Predictive Accuracy of Stroke Risk Prediction Models Across Black and White Race, Sex, and Age Groups
CONCLUSIONS AND RELEVANCE: In this analysis of Black and White individuals without stroke or transient ischemic attack among 4 US cohorts, existing stroke-specific risk prediction models and novel machine learning techniques did not significantly improve discriminative accuracy for new-onset stroke compared with the pooled cohort equations, and the REGARDS self-report model had the best calibration. All algorithms exhibited worse discrimination in Black individuals than in White individuals, indicating the need to expand the pool of risk factors and improve modeling techniques to address observed racial disparities and imp...
Source: Atherosclerosis - January 24, 2023 Category: Cardiology Authors: Chuan Hong Michael J Pencina Daniel M Wojdyla Jennifer L Hall Suzanne E Judd Michael Cary Matthew M Engelhard Samuel Berchuck Ying Xian Ralph D'Agostino George Howard Brett Kissela Ricardo Henao Source Type: research
Machine learning and acute stroke imaging
Conclusions
ML in acute ischemic stroke imaging has already made tremendous headway. Additional applications and further integration with clinical care is inevitable. Thus, facility with these approaches is critical for the neurointerventional clinician.
Source: Journal of NeuroInterventional Surgery - January 11, 2023 Category: Neurosurgery Authors: Sheth, S. A., Giancardo, L., Colasurdo, M., Srinivasan, V. M., Niktabe, A., Kan, P. Tags: Neuroimaging Source Type: research
Diagnostic model constructed by nine inflammation-related genes for diagnosing ischemic stroke and reflecting the condition of immune-related cells
ConclusionsTaken together, the diagnostic model constructed using the inflammation-related genes TNFSF10, ID1, PAQR8, OSR2, PDK4, PEX11B, TNIP1, FFAR2, and JUN exhibited high and specific diagnostic value for IS and reflected the condition of lymphocytes, monocytes, and neutrophils in the blood. The diagnostic model may contribute to the diagnosis of IS.
Source: Frontiers in Immunology - December 13, 2022 Category: Allergy & Immunology Source Type: research
Increased Risk of Stroke Linked to Stress at Home, Work
Experiencing multiple stressful events or chronic stress at home or at work over the course of a year raises the risk of several types of stroke, astudy published today inJAMA Network Open has found. However, the study also suggests that having a greater sense of control over the situations and experiences that affect one ’s life—a greater locus of control—may help counter the impact of stress on stroke risk.Catriona Reddin, M.B., of the University of Galway in Ireland and colleagues analyzed data from 26,812 participants in the INTERSTROKE study, an international case-control study of risk factors for stroke. Among ...
Source: Psychiatr News - December 9, 2022 Category: Psychiatry Tags: home stress INTERSTROKE study JAMA Network Open locus of control work stress Source Type: research
Machine learning approach for hemorrhagic transformation prediction: Capturing predictors' interaction
ConclusionCerebral microbleeds, NIHSS, and infarction size were identified as HT predictors. The best predicting models were RFC and GBC capable of capturing nonlinear interaction between predictors. Predictor interaction suggests a dynamic, rather than, fixed cutoff risk value for any of these predictors.
Source: Frontiers in Neurology - November 24, 2022 Category: Neurology Source Type: research
Is This Primary Exertional Headache?
Discussion
Commonly occurring primary headaches include tension, cluster and migraine headaches. “Other primary headaches” are often situational. Patients can have more than 1 type of these “other” headaches along with more common headaches. Other primary headaches as a group tend to be self-limited with long remission periods. Some other primary headaches include:
Thunderclap headache
Explosive sudden onset with maximum intensity in less 1 minute and resolution within 5 minutes usually
43/100,000 persons in adults
Primary or secondary
Secondary causes include intracranial hemorrhage, stroke, thro...
Source: PediatricEducation.org - November 21, 2022 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news
Ischemic stroke of unclear aetiology: a case-by-case analysis and call for a multi-professional predictive, preventive and personalised approach
AbstractDue to the reactive medical approach applied to disease management, stroke has reached an epidemic scale worldwide. In 2019, the global stroke prevalence was 101.5 million people, wherefrom 77.2 million (about 76%) suffered from ischemic stroke; 20.7 and 8.4 million suffered from intracerebral and subarachnoid haemorrhage, respectively. Globally in the year 2019 — 3.3, 2.9 and 0.4 million individuals died of ischemic stroke, intracerebral and subarachnoid haemorrhage, respectively. During the last three decades, the absolute number of cases increased substantially. The current prevalence of stroke is 110 million ...
Source: EPMA Journal - November 17, 2022 Category: International Medicine & Public Health Source Type: research
Specific signature biomarkers highlight the potential mechanisms of circulating neutrophils in aneurysmal subarachnoid hemorrhage
Conclusion: We identified core regulatory genes influencing the transcription profiles of circulating neutrophils after the rupture of intracranial aneurysms using bioinformatics analysis and machine learning algorithms. This study provides new insight into the mechanism of peripheral immune response and inflammation after aSAH.
Source: Frontiers in Pharmacology - November 10, 2022 Category: Drugs & Pharmacology Source Type: research
Brain PET and Cerebrovascular Disease
Cerebrovascular disease encompasses a broad spectrum of diseases such as stroke, hemorrhage, and cognitive decline associated with vascular narrowing, obstruction, rupture, and inflammation, among other issues. Recent advances in hardware and software have led to improvements in brain PET. Although still in its infancy, machine learning using convolutional neural networks is gaining traction in this area, often with a focus on providing high-quality images with reduced noise using a shorter acquisition time or less radiation exposure for the patient.
Source: PET Clinics - October 27, 2022 Category: Radiology Authors: Katarina Chiam, Louis Lee, Phillip H. Kuo, Vincent C. Gaudet, Sandra E. Black, Katherine A. Zukotynski Source Type: research
Can machine learning of post-procedural cone-beam CT images in acute ischemic stroke improve the detection of 24-h hemorrhagic transformation? A preliminary study
ConclusionML demonstrates high-sensitivity but low-accuracy 24-h HT prediction in AIS. The automated CB-CT imaging evaluation resizes sensitivity, specificity, and accuracy rates of visual interpretation reported in the literature so far. A standardized quantitative interpretation of CB-CT may be warranted to overcome the inter-operator variability.
Source: Neuroradiology - October 25, 2022 Category: Radiology Source Type: research
