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Total 2108 results found since Jan 2013.
Association of beta-2-microglobulin, cystatin C and lipocalin-2 with stroke risk in the general Chinese population
CONCLUSION: Elevated serum B2M, cystatin C and LCN-2 levels are associated with stroke risk. They may be novel biomarkers for clinicians to assess stroke risk.Key messagesSerum beta-2-microglobulin, cystatin C and lipocalin-2 levels are significantly associated with stroke risk.Beta-2-microglobulin, cystatin C and lipocalin-2 may serve as useful biomarkers for stroke risk stratification in the general population.PMID:37155257 | PMC:PMC10167872 | DOI:10.1080/07853890.2023.2203516
Source: Annals of Medicine - May 8, 2023 Category: Internal Medicine Authors: Juanying Zhen Shuyun Liu Ryan Yan Lam Kam Guoru Zhao Hao Peng Jianguo Liang Aimin Xu Chao Li Lijie Ren Jun Wu Bernard Man Yung Cheung Source Type: research
Dietary exposure to polychlorinated biphenyls is associated with increased risk of stroke in women
ConclusionDietary exposure to PCBs was associated with an increased stroke risk in women, especially hemorrhagic stroke. The results provide important information regarding the risk‐benefit analysis of fish consumption, particularly for cerebrovascular disease prevention.This article is protected by copyright. All rights reserved.
Source: Journal of Internal Medicine - January 16, 2014 Category: Internal Medicine Authors: Charlotte Bergkvist, Maria Kippler, Susanna C. Larsson, Marika Berglund, Anders Glynn, Alicja Wolk, Agneta Åkesson Tags: Original Source Type: research
Formal and informal prediction of recurrent stroke and myocardial infarction after stroke: a systematic review and evaluation of clinical prediction models in a new cohort
Conclusions:
The available models for recurrent stroke discriminate poorly between patients with and without a recurrent stroke or MI which was similar to the discrimination achieved by informal clinicians' predictions. Formal prediction may be improved by addressing commonly encountered methodological flaws.
Source: BMC Medicine - April 4, 2014 Category: Internal Medicine Authors: Douglas ThompsonGordon MurrayMartin DennisCathie SudlowWilliam Whiteley Source Type: research
Is female sex a risk factor for stroke and thromboembolism in patients with atrial fibrillation? A systematic review and meta-analysis
Conclusions: Women with AF are at increased risk of stroke, particularly elderly women. Comprehensive stroke risk assessment, including sex as a risk factor, should be undertaken in all AF patients.
Source: QJM - November 24, 2014 Category: Internal Medicine Authors: Wagstaff, A. J., Overvad, T. F., Lip, G. Y. H., Lane, D. A. Tags: Reviews Source Type: research
Warfarin Use and Risk of Stroke in Patients With Atrial Fibrillation Undergoing Hemodialysis: A Meta-Analysis
Abstract: In spite of the substantial burden of atrial fibrillation and associated elevated ischemic stroke risk in patients undergoing hemodialysis, the role of warfarin in these high-risk patients remains uncertain. Our objective was to clarify the association between warfarin use and risk of stroke for patients with atrial fibrillation undergoing dialysis.
PubMed and Embase from January 1966 to January 2015 were searched to identify relevant studies. Inclusion criteria were cohort studies, patients with atrial fibrillation undergoing hemodialysis, and reported quantitative estimates of the multivariate adjusted relativ...
Source: Medicine - February 1, 2016 Category: Internal Medicine Tags: Research Article: Meta-Analysis of Observ Studies in Epidemiology Source Type: research
Early High-dosage Atorvastatin Treatment Improved Serum Immune-inflammatory Markers and Functional Outcome in Acute Ischemic Strokes Classified as Large Artery Atherosclerotic Stroke: A Randomized Trial
Abstract: Statins have beneficial effects on cerebral circulation and brain parenchyma during ischemic stroke and reperfusion. The primary hypothesis of this randomized parallel trial was that treatment with 80 mg/day of atorvastatin administered early at admission after acute atherosclerotic ischemic stroke could reduce serum levels of markers of immune-inflammatory activation of the acute phase and that this immune-inflammatory modulation could have a possible effect on prognosis of ischemic stroke evaluated by some outcome indicators.
We enrolled 42 patients with acute ischemic stroke classified as large arteries ath...
Source: Medicine - March 1, 2016 Category: Internal Medicine Tags: Research Article: Clinical Trial/Experimental Study Source Type: research
The Relationships Among Regionalization, Processes, and Outcomes for Stroke Care: A Nationwide Population-based Study
We examined the association of regionalization with processes and outcomes, and the mediating effect of processes of care on the association between regionalization and mortality for acute stroke in Taiwan.
We analyzed all 229,568 admissions with acute ischemic stroke from January 2004 to September 2012 through Taiwan's National Health Insurance Research Database.
Regionalized care for acute stroke has been implemented since July 2009 in Taiwan.
Rates of thrombolytic therapy within 3 hours after onset of ischemic stroke, average numbers of processes of care, and 30-day mortality rates at monthly intervals for baseline...
Source: Medicine - April 1, 2016 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
Risk of sudden sensorineural hearing loss in stroke patients: A 5-year nationwide investigation of 44,460 patients
This study employed a nationwide population-based dataset to investigate the relationship between stroke and SSNHL.
The Taiwan Longitudinal Health Insurance Database was used to compile data from 11,115 stroke patients and a comparison cohort of 33,345 matched nonstroke enrollees. Each patient was followed for 5 years to identify new-onset SSNHL. Stratified Cox proportional-hazard regression analysis was used to examine the association of stroke with subsequent SSNHL.
Among the 44,460 patients, 66 patients (55,378 person-years) from the stroke cohort and 105 patients (166,586 person-years) from the comparison cohort were...
Source: Medicine - September 1, 2016 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
Management of acute ischaemic stroke in patients with dementia
Abstract
An estimated 10% of stroke patients have an underlying dementia. As a consequence, health professionals often face the challenge of managing patients with dementia presenting with an acute stroke. Patients with dementia are less likely to receive thrombolysis (0.56–10% vs. 1–16% thrombolysis rates in the general population), be admitted to a stroke unit or receive some types of care. Anticoagulation for secondary stroke prevention is sometimes withheld, despite dementia not being listed as an exclusion criterion in current guidelines. Studies in this population are scarce, and results have been contradictory. ...
Source: Journal of Internal Medicine - February 1, 2017 Category: Internal Medicine Authors: A. Subic, P. Cermakova, B. Norrving, B. Winblad, M. Euler, M. G. Kramberger, M. Eriksdotter, S. Garcia ‐Ptacek Tags: Review Source Type: research
Pregnancy increases stroke risk up to 1 year postpartum and reduces long-term risk
Conclusion: The risk of stroke was elevated during the first year postpartum, but lower in subsequent years. Stroke risk increased in multiparous ( ≥3) women. Physicians should be on alert for pregnancy complications and ensure appropriate management to prevent postpartum stroke.
Source: QJM - January 9, 2017 Category: Internal Medicine Source Type: research
Antidiabetic drugs and stroke risk. Current evidence.
Abstract
Cardiovascular disease (CVD) is the major cause of morbidity and mortality for individuals with type 2 diabetes (T2D). In particular, the risk for stroke is twice that of patients without diabetes, and diabetes may be responsible for >8% of first ischemic strokes. Therefore, the way to prevent stroke in these patients has become an important issue. Traditionally, glucose-lowering drugs had not been shown to protect against stroke. Moreover, several antidiabetic drugs (i.e., sulfonylureas, rosiglitazone) have been reported to be associated with increased risks of CVD and stroke. On the contrary, data on...
Source: European Journal of Internal Medicine - September 20, 2017 Category: Internal Medicine Authors: Castilla-Guerra L, Fernandez-Moreno MDC, Leon-Jimenez D, Carmona-Nimo E Tags: Eur J Intern Med Source Type: research
Device Closure Versus Medical Therapy Alone for Patent Foramen Ovale in Patients With Cryptogenic Stroke: A Systematic Review and Meta-analysis.
Conclusion: In patients with PFO and cryptogenic stroke, transcatheter device closure decreases risk for recurrent stroke compared with medical therapy alone. Because recurrent stroke rates are low even with medical therapy alone and PFO closure might affect AF risk, shared decision making is crucial for this treatment.
Primary Funding Source: None.
PMID: 29310136 [PubMed - as supplied by publisher]
Source: Annals of Internal Medicine - January 9, 2018 Category: Internal Medicine Authors: Shah R, Nayyar M, Jovin IS, Rashid A, Bondy BR, Fan TM, Flaherty MP, Rao SV Tags: Ann Intern Med Source Type: research
The association between serum uric acid levels and ischemic stroke in essential hypertension patients.
Conclusions: SUA was an independent risk factor for ischemic stroke, and also have a good predictive value ischemic stroke among hypertensive patients in Chinese community.
PMID: 32303139 [PubMed - as supplied by publisher]
Source: Postgraduate Medicine - April 19, 2020 Category: Internal Medicine Tags: Postgrad Med Source Type: research
Correlation between self-perceived burden and self-management behavior in elderly stroke survivors: A longitudinal observational study
The aim of this study was to assess the levels of self-perceived burden (SPB) and self-management behavior in elderly stroke survivors during the first 3 months after acute stroke, and to explore the correlation between them.
A total of 203 consecutive hospitalized elderly patients diagnosed with stroke were recruited. Self-perceived Burden Scale and Stroke Self-management Scale in 1 month (T1) and 3 months (T2) post-stroke were assessed and compared.
The score of SPB in elderly stroke survivors was 28.96 ± 5.50 and 27.25 ± 6.17 at T1 and T2, respectively. Stroke self-management scale scored 165.93 ± 9.82 ...
Source: Medicine - October 29, 2020 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
Effect of tele-stroke application on length of stay and outcome of stroke unit inpatients
CONCLUSIONOur study concluded that application of tele stroke had significant improvement in stroke unit care as regard length of stay, rapid improvement of patients according to NIH scoring and mRS
Source: QJM - October 1, 2021 Category: Internal Medicine Source Type: research
