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Total 2108 results found since Jan 2013.
Sitagliptin After Ischemic Stroke in Type 2 Diabetic Patients: A Nationwide Cohort Study
Abstract: The cerebrovascular safety and efficacy of sitagliptin, a dipeptidyl peptidase-4 inhibitor, in patients with type 2 diabetes mellitus (T2DM) with ischemic stroke remains uncertain. The aim of this study was to assess the efficacy and safety of sitagliptin in patients with T2DM with recent ischemic stroke.
We analyzed data from the Taiwan National Health Insurance Research Database between March 1, 2009, and December 31, 2011. Ischemic stroke patients were identified from individuals with T2DM. Patients who received sitagliptin were compared with those who did not to evaluate the cardiovascular safety and efficacy...
Source: Medicine - July 1, 2015 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
Association Between Kidney Stones and Risk of Stroke: A Nationwide Population-Based Cohort Study
This study explored whether patients with renal stones were at a higher stroke risk than those without renal stones. A national insurance claim dataset of 22 million enrollees in Taiwan was used to identify 53,659 patients with renal stones, and 214,107 were selected as age-, sex-, and comorbidity-matched controls for a 13-year follow-up.
The relative stroke risk for the RS cohort was 1.06-fold higher than that for the non-RS group (95% confidence interval [CI] = 1.01–1.11). Age-specific analysis revealed that the adjusted stroke risk for the RS cohort increased as age decreased, with the highest risk of 1.47-fold (...
Source: Medicine - February 1, 2016 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
Effect of prestroke antiplatelets use on first‐ever ischaemic stroke severity and early outcome
ConclusionsOur findings provide further evidence supporting modest benefit of AP therapy on the course and outcome of first‐ever ischaemic stroke. Further large studies are needed to confirm this effect.
Source: International Journal of Clinical Practice - March 31, 2016 Category: Internal Medicine Authors: J. P. Bembenek, M. Niewada, M. Karlinski, A. Czlonkowska Tags: Original Paper Source Type: research
Stroke in young adults: Incidence rate, risk factors, treatment and prognosis
Conclusions The majority of stroke events in patients 55 years of age or younger appear to be related to a high prevalence of classical cardiovascular risk factors and possibly to psychosocial stress.
Source: Revista Clinica Espanola - June 29, 2016 Category: Internal Medicine Source Type: research
Plasma growth differentiation factor 15 predicts first-ever stroke in hypertensive patients
The objective of this study was to evaluate the clinical implications of plasma GDF-15 on the development of first-ever stroke in patients with hypertension.
In total, 254 patients with hypertension without a history of stroke were included from March 2010 to August 2010 and followed up until June 2013. The baseline circulating GDF-15 was determined by enzyme-linked immunosorbent assays.
During a follow-up of 3.0 ± 0.6 years, 22 (8.7%) first-ever strokes were identified, including 12 ischemic strokes and 10 intracerebral hemorrhages (ICH). According to tertiles of GDF-15, survival free of first-ever stroke was lower...
Source: Medicine - July 1, 2016 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
Under-prescribing of Prevention Drugs and Primary Prevention of Stroke and Transient Ischaemic Attack in UK General Practice: A Retrospective Analysis
ConclusionsIn our study, over half of people eligible for lipid-lowering, anticoagulant, or antihypertensive drugs were not prescribed them prior to first stroke/TIA. We estimate that approximately 12,000 first strokes could potentially be prevented annually in the UK through optimal prescribing of these drugs. Improving prescription of lipid-lowering, anticoagulant, and antihypertensive drugs is important to reduce the incidence and burden of stroke and TIA.
Source: PLoS Medicine - November 14, 2016 Category: Internal Medicine Authors: Grace M. Turner Source Type: research
Different impact of aspirin on renal progression in patients with predialysis advanced chronic kidney disease with or without previous stroke.
CONCLUSIONS: There was no significant benefit in preventing ischemic stroke in the patients with advanced CKD who received aspirin therapy. Furthermore, the use of aspirin was associated with the risk of renal failure in the patients with advanced CKD without previous stroke.
PMID: 27884500 [PubMed - as supplied by publisher]
Source: European Journal of Internal Medicine - November 20, 2016 Category: Internal Medicine Authors: Hsiao KC, Huang JY, Lee CT, Hung TW, Liaw YP, Chang HR Tags: Eur J Intern Med Source Type: research
A strategic framework improves access to stroke reperfusion across the state of Victoria, Australia
ConclusionsA strategic and region‐specific approach has resulted in improved access by road transport to reperfusion therapies for stroke patients across Victoria.
Source: Internal Medicine Journal - May 30, 2017 Category: Internal Medicine Authors: Janet E. Bray, Sonia Denisenko, Bruce C.V. Campbell, Michael Stephenson, Jason Muller, Grant Hocking Grad, Peter J. Hand, Christopher F. Bladin Tags: Original Article Source Type: research
Urolithiasis is associated with an increased risk of stroke: A population ‐based 5‐year follow‐up study
ConclusionsIn conclusion, the present study detected an increased risk of both ischemic and hemorrhagic stroke in patients with urolithiasis, particularly in those older than 40 years old.
Source: Internal Medicine Journal - September 11, 2017 Category: Internal Medicine Authors: Ping ‐Song Chou, Wei‐Pin Chang, Yii‐Her Chou Tags: Original Article Source Type: research
Reflection on Stroke Deaths and end ‐of‐life stroke care
ConclusionIn this cohort, palliative care referral and EOLCP were commenced in less than 50% of patients, highlighting significant variations in clinical care. These data support the need to promote awareness of ACP, particularly in patients with prior stroke or significant co‐morbidities. This may help reduce potentially futile invasive investigations and treatment.
Source: Internal Medicine Journal - September 11, 2017 Category: Internal Medicine Authors: Syed Zujajuddin Quadri, Thang Huynh, Cecilia Cappelen ‐Smith, Nirupama Wijesuriya, Abul Mamun, Roy Beran, Alan Mcdougall, Dennis Cordato Tags: Original Article Source Type: research
Comparing associations of different metabolic syndrome definitions with ischemic stroke in Chinese elderly population.
CONCLUSION: In this population, Updated ATPIII criteria was a more suitable definition of Mets than definitions of Chinese guide, IDF and JIS for screening high-risk individuals of ischemic stroke, and the additive effects of Mets components might play a greater role than its composition alone in ischemic stroke.
PMID: 29092746 [PubMed - as supplied by publisher]
Source: European Journal of Internal Medicine - October 29, 2017 Category: Internal Medicine Authors: Liu Q, Li YX, Hu ZH, Jiang XY, Li SJ, Wang XF Tags: Eur J Intern Med Source Type: research
Efficacy of Tai Chi and qigong for the prevention of stroke and stroke risk factors: A systematic review with meta-analysis
Conclusion:
Although Tai Chi and qigong show some potential more robust studies are required to provide conclusive evidence on the efficacy and safety of Tai Chi and qigong for reducing major stroke risk factors.
Source: Medicine - November 1, 2017 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research
Percutaneous Closure Versus Medical Treatment in Stroke Patients With Patent Foramen Ovale: A Systematic Review and Meta-analysis.
Conclusion: Compared with medical treatment, PFO closure prevents recurrent stroke and TIA but increases the incidence of AF or AFL in PFO carriers with cryptogenic stroke.
Primary Funding Source: Italian Ministry of Education, University and Research (MIUR). (PROSPERO: CRD42017074686).
PMID: 29310133 [PubMed - as supplied by publisher]
Source: Annals of Internal Medicine - January 9, 2018 Category: Internal Medicine Authors: De Rosa S, Sievert H, Sabatino J, Polimeni A, Sorrentino S, Indolfi C Tags: Ann Intern Med Source Type: research
Association of smoking with risk of stroke in middle-aged and older Chinese: Evidence from the China National Stroke Prevention Project
This study aimed to investigate the association between smoking and risk of stroke in middle-aged and older Chinese adults, based on the data from the China National Stroke Prevention Project.
A community-based cross-sectional study with 12,704 (5681 men, 7023 women) Chinese adults aged ≥40 years was conducted to examine the association of smoking with stroke. Multivariable logistic regression was used to calculate odds ratios (ORs) and 95% confidence intervals (CIs).
Among the study population, a total of 524 stroke survivors were identified. The age-adjusted prevalence of stroke was 4.06% for both sexes, 2.95% for wo...
Source: Medicine - November 1, 2018 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
Clinical characteristics of dysphagic stroke patients with salivary aspiration: A STROBE-compliant retrospective study
In conclusion, care should be taken to prevent salivary aspiration when the MMSE score is less than eight in patients with supratentorial stroke, and the transfer sub-score of MBI score is less than three in patients with infratentorial stroke.
Source: Medicine - March 1, 2019 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
