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Total 299 results found since Jan 2013.

Saving Vanessa, part 1: A mystery rash, a stroke and an epic rescue
Vanessa’s rash first appeared on her arms and legs when she 3 or 4 months old. It was red and bumpy and went away when she was sick with a virus, which happened often. Then it would come back. The dermatology team she saw at Boston Children’s Hospital was puzzled. “I was expecting they were going to think it was nothing, but they took it very seriously,” says Katherine Bell, one of Vanessa’s mothers. “They took a biopsy and very quickly realized they had no idea what it was.” Vanessa’s case was even featured at a regional dermatology conference where doctors take up mystery patients. “A hundred to 150 der...
Source: Thrive, Children's Hospital Boston - July 25, 2017 Category: Pediatrics Authors: Nancy Fliesler Tags: Diseases & Conditions Our Patients’ Stories Dr. Carolyn Rogers Dr. Pui Lee Dr. Robert Sundel Dr. Scellig Stone Dr. Todd Lyons stroke Source Type: news

Immunotherapy for arterial ischaemic stroke in childhood: a systematic review
Conclusions Immunotherapies are used in children with AIS, mainly as steroids for children with arteriopathy. However, there is currently little robust evidence to either encourage or discourage this practice. There is weak evidence consistent with the hypothesis that in certain children at risk, steroids may both reduce the risk of occurrent/recurrent stroke and enhance neurological outcomes. As the potential benefit is still uncertain, this indicates that a trial of steroids in childhood AIS may be justified.
Source: Archives of Disease in Childhood - April 19, 2017 Category: Pediatrics Authors: Edwards, H. B., Mallick, A. A., O'Callaghan, F. J. K. Tags: Clinical trials (epidemiology), Epidemiologic studies, Immunology (including allergy), Stroke, Child health Original article Source Type: research

Paediatric cerebral sinovenous thrombosis: findings of the International Paediatric Stroke Study
Conclusions Our study extends the observations of previously published smaller studies in children with CSVT that this is a morbid disease with diverse underlying causes and risk factors. Divergent treatment practices among highly specialised centres as well as limited data on treatment efficacy and safety suggest that further study of this condition is warranted.
Source: Archives of Disease in Childhood - January 20, 2015 Category: Pediatrics Authors: Ichord, R. N., Benedict, S. L., Chan, A. K., Kirkham, F. J., Nowak-Gottl, U., Ashwal, deVeber, Ferriero, Fullerton, Ichord, Kirkham, Lynch, O'Callaghan, Pavlakis, Sebire, Willan, Kirton, Moharir, Sofronas, Nowak-Gottl, During, Krumpel, Dowling, Plumb, Jou Tags: Epidemiologic studies, Drugs: cardiovascular system, Epilepsy and seizures, Headache (including migraine), Pain (neurology), Stroke, Child health, Memory disorders (psychiatry) Original article Source Type: research

Pediatric Acute Stroke Protocols in the United States and Canada
To describe existing pediatric acute stroke protocols to understand better how pediatric centers might implement such pathways within the context of institution-specific structures.
Source: The Journal of Pediatrics - November 10, 2021 Category: Pediatrics Authors: Dana B. Harrar, Giulia M. Benedetti, Anuj Jayakar, Jessica L. Carpenter, Tara K. Mangum, Melissa Chung, Brian Appavu, International Pediatric Stroke Study Group, Pediatric Neurocritical Care Research Group Tags: Original Articles Source Type: research

What Are the Classifications of Perinatal Stroke?
Discussion Perinatal stroke occurs in about 1:1000 live births and is a “focal vascular injury from the fetal period to 28 days postnatal age.” Perinatal stroke is the most common cause of hemiparetic cerebral palsy and causes other significant morbidity including cognitive deficits, learning disabilities, motor problems, sensory problems including visual and hearing disorders, epilepsy, and behavioral and psychological problems. Family members are also affected because of the potential anxiety and guilt feelings that having a child with a stroke presents, along with the care that may be needed over the child&#...
Source: PediatricEducation.org - May 1, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Stroke and migraine is there a possible comorbidity?
In conclusion the association between migraine and stroke remains an open question. Solving the above mentioned issues is fundamental to understand the epidemiologic, pathogenetic and clinical aspects of migraine-related stroke.
Source: Italian Journal of Pediatrics - April 25, 2016 Category: Pediatrics Source Type: research

Management and 2-year follow-up of children aged 29days to 17years hospitalized for a first stroke in France (2009-2010).
CONCLUSION: This is the first study to report the epidemiology of childhood stroke in France. The validity of this study is supported by the fact that it demonstrated homogeneous descriptive indicators to those obtained by means of various methodologies in other populations. The high mortality, recurrence, and disability rates observed during the year following the initial stroke encourage continuation of the ongoing process of standardizing the management of childhood stroke in France. PMID: 25287139 [PubMed - as supplied by publisher]
Source: Archives de Pediatrie - October 3, 2014 Category: Pediatrics Authors: Tuppin P, Samson S, Woimant F, Chabrier S Tags: Arch Pediatr Source Type: research

Genetic determinants and stroke in children with sickle cell disease.
CONCLUSION: There is a high incidence of stroke in male children and in children with SCA. Coexistence with α-thal and haplotypes of the beta globin chain cluster did not show any significant association with stroke. The heterogeneity between previously evaluated populations, the non-reproducibility between studies, and the need to identify factors associated with stroke in patients with SCA indicate the necessity of conducting further research to demonstrate the relevance of genetic factors in stroke related to SCD. PMID: 27268459 [PubMed - as supplied by publisher]
Source: Jornal de Pediatria - June 3, 2016 Category: Pediatrics Authors: Rodrigues DO, Ribeiro LC, Sudário LC, Teixeira MT, Martins ML, Pittella AM, Junior IO Tags: J Pediatr (Rio J) Source Type: research

Diffuse optical tomography for the detection of perinatal stroke at the cot side: a pilot study.
CONCLUSION: This suggests that DOT and correlation-based analyses in the low-frequency range can potentially aid the early detection of perinatal stroke, prior to MRI acquisition. Additional methodological advances are required to increase the sensitivity and specificity of this technique. PMID: 30759451 [PubMed - as supplied by publisher]
Source: Pediatric Research - February 13, 2019 Category: Pediatrics Authors: Chalia M, Dempsey LA, Cooper RJ, Lee CW, Gibson AP, Hebden JC, Austin T Tags: Pediatr Res Source Type: research

West Virginia University Pediatric Stroke Registry: Clinical Description and Risk Factors Identification in Patients From a Rural Area
Conclusion. Patients with the most common risk factors for stroke (cardiac disease) were overrepresented. This suggests that in children receiving medical attention in rural areas less common risk factors for stroke might not be identified, increasing the risk recurrence. Increased index of suspicion is needed about pediatric stroke in rural areas, and early transfer to a tertiary care center for identification of risk factors is mandatory.
Source: Clinical Pediatrics - December 2, 2014 Category: Pediatrics Authors: Pergami, P., Thayapararajah, S. W., Seemaladinne, N. Tags: Articles Source Type: research

Short ‐term neurological outcomes in ischemic and hemorrhagic pediatric stroke
ConclusionsPediatric stroke is associated with poor prognosis in a substantial number of patients in short term, with CSVT having the worst prognosis. Not only ischemic but also hemorrhagic stroke were presented with detailed patient characteristics, with a full thrombosis panel achieved for most ischemic stroke patients.This article is protected by copyright. All rights reserved.
Source: Pediatrics International - November 18, 2018 Category: Pediatrics Authors: Tu ğçe Aksu Uzunhan, Nur Aydinli, Mine Çalişkan, Burak Tatli, Meral Özmen Tags: Original Articles Source Type: research

Nonpharmacological rehabilitation interventions for motor and cognitive outcomes following pediatric stroke: a systematic review
Conclusion: Effective rehabilitation approaches are important for optimizing outcomes in children who have had a stroke. Although the number of published clinical trials has increased in recent years, little evidence-based guidance exists for this clinical population.What is Known:• Pediatric stroke is a significant cause of disability in children that is often associated with long-term motor and cognitive sequelae.• There is a need to establish a knowledge base regarding available evidence-based rehabilitation therapies for this clinical population.What is New:• Most studies examining interventions for motor functio...
Source: European Journal of Pediatrics - February 27, 2019 Category: Pediatrics Source Type: research

Evaluation of perinatal arterial ischemic stroke using non-invasive arterial spin labeling perfusion MR imaging.
Conclusion:ASL perfusion MR imaging is able to reliably detect hypo- and hyperperfusion in PAIS patients and can be used to monitor the evolution of perfusion after an ischemic event.Pediatric Research (2013); doi:10.1038/pr.2013.111. PMID: 23797533 [PubMed - as supplied by publisher]
Source: Pediatric Research - June 24, 2013 Category: Pediatrics Authors: De Vis JB, Petersen ET, Kersbergen KJ, Alderliesten T, de Vries LS, van Bel F, Groenendaal F, Lemmers PM, Hendrikse J, Benders MJ Tags: Pediatr Res Source Type: research

Antithrombotic Therapy for Secondary Stroke Prevention in Bacterial Meningitis in Children
Conclusion: In this small sample, heparin and ASA appeared to be safe in childhood bacterial meningitis complicated by stroke and may be effective in improving outcome. Heparin may be more effective than aspirin in preventing recurrent infarction.
Source: The Journal of Pediatrics - July 24, 2014 Category: Pediatrics Authors: Cyrus Boelman, Manohar Shroff, Ivanna Yau, Bruce Bjornson, Susan Richrdson, Gabrielle deVeber, Daune MacGregor, Mahendranathn Moharir, Rand Askalan Tags: Original Articles Source Type: research

Use of Oxygen Pulse in Predicting Doppler-Derived Maximal Stroke Volume in Adolescents.
This study examined both of these issues in a cohort of 44 healthy adolescent males and females (ages 14-16 years) who performed routine progressive cycle exercise to exhaustion. Gas exchange variables were measured by standard open circuit techniques. Stroke volume at rest and during exercise was assessed by the Doppler ultrasound method. At peak exercise O2 pulse correlated closely with stroke volume (r=0.73) with a SEE of 12.6 mL·beat-1. Values of maximal O2 pulse in non-athletic boys and girls were 13.3 ± 2.5 and 11.0 ± 1.7 mL·beat-1, respectively. After the initial workload, a steady rise was observed in O2 pulse,...
Source: Pediatric Exercise Science - July 17, 2015 Category: Pediatrics Authors: Unnithan V, Rowland TW Tags: Pediatr Exerc Sci Source Type: research