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Total 299 results found since Jan 2013.

Paediatric arterial ischemic stroke: acute management, recent advances and remaining issues
Stroke is a rare disease in childhood with an estimated incidence of 1-6/100.000. It has an increasingly recognised impact on child mortality along with its outcomes and effects on quality of life of patients and their families. Clinical presentation and risk factors of paediatric stroke are different to those of adults therefore it can be considered as an indipendent nosological entity. The relative rarity, the age-related peculiarities and the variety of manifested symptoms makes the diagnosis of paediatric stroke extremely difficult and often delayed. History and clinical examination should investigate underlying diseas...
Source: Italian Journal of Pediatrics - December 2, 2015 Category: Pediatrics Authors: Margherita RosaSilvana De LuciaVictoria RinaldiJulie Le GalMarie DesmarestClaudio VeropalumboSilvia RomanelloLuigi Titomanlio Source Type: research

Neonatal arterial ischemic stroke in term or near-term newborns: prevalence and risk factors.
Abstract The general designation ischemic perinatal stroke includes several disease states that differ in pathophysiology, timing of occurrence and presentation. While it seems logical to assume that their prevalence and their risk factors depend primarily on the considered type of stroke, most studies used inconsistent definitions or included heterogeneous populations, which limits their accuracy. Given these biases, the French Society of Neonatology and the French Centre for Paediatric Stroke wished to update the knowledge in this domain, focusing on a specific form of perinatal stroke, i.e neonatal arterial isc...
Source: Archives de Pediatrie - September 1, 2017 Category: Pediatrics Authors: Darmency-Stamboul V, Cordier AG, Chabrier S Tags: Arch Pediatr Source Type: research

Neuroprotective effects of Sonic hedgehog agonist SAG in a rat model of neonatal stroke
CONCLUSIONS: These findings indicate benefit of one-time SAG treatment post insult in reducing brain injury and improving behavioral outcome after experimental neonatal stroke.IMPACT: A one-time dose of small molecule Sonic hedgehog agonist protected against neonatal stroke and improved long-term behavioral outcomes in a rat model. This study extends the use of Sonic hedgehog in treating developing brain injury, previously shown in animal models of Down syndrome and cerebellar injury. Sonic hedgehog agonist is one of the most promising therapies in treating neonatal stroke thanks to its safety profile and low dosage.PMID:3...
Source: Pediatric Research - March 3, 2021 Category: Pediatrics Authors: Vien Nguyen Manideep Chavali Amara Larpthaveesarp Srikirti Kodali Ginez Gonzalez Robin J M Franklin David H Rowitch Fernando Gonzalez Source Type: research

Effect of Age, Sex and Race Distance on Front Crawl Stroke Parameters in Sub-elite Adolescent Swimmers During Competition.
Abstract The aims of this study were to determine the effect of age, sex and race distance on velocity (v), stroke rate (SR), stroke length (SL) and stroke index (SI) of sub-elite adolescent swimmers in competition, and to investigate their pacing strategies during the 100 m and 200 m events. Video footage of 112 adolescent swimmers (56 female; 56 male), competing in the 100 m and 200 m freestyle events, in two age groups (12-14; 15-18 years) was recorded and subsequently analyzed. A MANOVA showed that all stroke parameters significantly differed between sexes and between race distances. The older adolescents had ...
Source: Pediatric Exercise Science - April 22, 2015 Category: Pediatrics Authors: Dormehl SJ, Osborough CD Tags: Pediatr Exerc Sci Source Type: research

Childhood arterial ischemic stroke in Senegal (West Africa).
Abstract Etiological factors of childhood ischemic stroke depend on the epidemiological context. The purpose of this study was to determine the risk factors, the clinical and radiologic features, and the outcome of arterial ischemic stroke in a case series of Senegalese children. We carried out a retrospective registry-based study on arterial ischemic stroke in children hospitalized in the neurology department of Fann Teaching Hospital and Albert Royer Children's Hospital, from January 2005 to December 2015. We enrolled 116 cases with an age range from 2 months to 18 years. The mean age at stroke occurrence was 71...
Source: Archives de Pediatrie - August 21, 2018 Category: Pediatrics Authors: Ndiaye M, Lengue F, Sagna SD, Sow AD, Fogany Y, Deme H, Basse AM, Diop-Sene MS, Diagne NS, Diop AG, Ndiaye O, Ndiaye MM Tags: Arch Pediatr Source Type: research

Symptom patterns in childhood arterial ischemic stroke: Analysis of a population-based study in Germany
Conclusions Any new focal neurological deficit in isolation, or associated with seizures or further non-specific symptoms should alert to childhood stroke. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Klinische Padiatrie - October 10, 2018 Category: Pediatrics Authors: Gerstl, Lucia Weinberger, Raphael von Kries, R üdiger Heinen, Florian Sebastian Schroeder, Andreas Veronika Bonfert, Michaela Borggr äfe, Ingo Tacke, Moritz Vill, Katharina N. Landgraf, Mirjam Kurnik, Karin Olivieri, Martin Tags: Original Article Source Type: research

Moving Toward a New Standard of Care for Acute Pediatric Stroke
This article summarizes the issues and presentations behind identifying acute pediatric stroke, the research behind these emerging therapies in children, and the process of successfully applying pediatric stroke protocols. [Pediatr Ann. 2021;50(6):e242-e244.].PMID:34115557 | DOI:10.3928/19382359-20210519-01
Source: Pediatric Annals - June 11, 2021 Category: Pediatrics Authors: Henry David Source Type: research