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Door‐to‐door survey of cardiovascular health, stroke, and ischemic heart disease in rural coastal Ecuador – the Atahualpa Project: methodology and operational definitions
DiscussionImplementation of public health strategies directed to improve the cardiovascular health status of a given population must be based on studies evaluating specific risk factors at regional levels. Epidemiologic surveys such as the Atahualpa Project may prove cost‐effective in improving the cardiovascular health status of people living in Latin American rural villages by increasing the knowledge on the particular needs of these populations.
Source: International Journal of Stroke - March 19, 2013 Category: Neurology Authors: Oscar H. Del Brutto, Ernesto Peñaherrera, Elio Ochoa, Milton Santamaría, Mauricio Zambrano, Victor J. Del Brutto, Tags: Protocols Source Type: research

Exercise‐induced changes in cardiovascular function after stroke: a randomized controlled trial
ConclusionsThis was the first study to examine the effects of aerobic exercise after stroke on cardiovascular hemodynamics. High‐intensity exercise improved right‐sided function and early myocardial relaxation. Low‐intensity exercise may also benefit plasma lipid, glucose and inflammatory markers, and ambulatory capacity. This study is an important step towards understanding mechanisms by which exercise may reduce cardiovascular risk and function.
Source: International Journal of Stroke - October 22, 2013 Category: Neurology Authors: Ada Tang, Janice J. Eng, Andrei V. Krassioukov, Kenneth M. Madden, Azam Mohammadi, Michael Y. C. Tsang, Teresa S. M. Tsang Tags: Research Source Type: research

Predicting Asymptomatic Coronary Artery Diseasein Patients With Ischemic Stroke and Transient Ischemic Attack: The PRECORIS Score Clinical Sciences
Conclusions— The PRECORIS score can identify a population of stroke or transient ischemic attack patients with a high prevalence of occult severe coronary artery stenosis.
Source: Stroke - December 23, 2013 Category: Neurology Authors: Calvet, D., Song, D., Yoo, J., Turc, G., Sablayrolles, J.-L., Choi, B. W., Heo, J. H., Mas, J.-L. Tags: Secondary prevention, Risk Factors, Coronary circulation Clinical Sciences Source Type: research

Prediction of Major Vascular Events after Stroke: The Stroke Prevention by Aggressive Reduction in Cholesterol Levels Trial
Conclusions: Both a baseline FCRS of 20% or more and a novel predictive model were associated with future MVEs in SPARCL trial subjects. The novel model needs to be validated, and the benefits of using either the FCRS or the novel model in clinical practice needs to be assessed.
Source: Journal of Stroke and Cerebrovascular Diseases - February 26, 2014 Category: Neurology Authors: Bruce Ovbiagele, Larry B. Goldstein, Pierre Amarenco, Michael Messig, Henrik Sillesen, Alfred Callahan, Michael G. Hennerici, Justin Zivin, K.Michael A. Welch, SPARCL Investigators Tags: Original Articles Source Type: research

Stroke in Very Old Patients (I2-1.004)
Conclusion: very elderly patients have a different risk factor profile, have more anterior circulation infarcts and have a worse prognosis with i creased mortality and increased length of stay in hospitalStudy Supported by:Disclosure: Dr. Dobi has nothing to disclose. Dr. Kapisyzi has nothing to disclose. Dr. Kruja has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Dobi, D., Kapisyzi, M., Kruja, J. Tags: New Antithrombotic Agents for Stroke Prevention Poster Presentations Source Type: research

Elevated Plasma YKL-40, Lipids and Lipoproteins, and Ischemic Vascular Disease in the General Population Clinical Sciences
Conclusions— Elevated YKL-40 was associated with a 34% increase in triglyceride levels and with a 2-fold increased risk of ischemic stroke, whereas genetically elevated YKL-40 were not.
Source: Stroke - January 26, 2015 Category: Neurology Authors: Kjaergaard, A. D., Johansen, J. S., Bojesen, S. E., Nordestgaard, B. G. Tags: Clinical genetics, Lipids, Cerebrovascular disease/stroke, Acute Cerebral Infarction, Genetics of Stroke, Epidemiology Clinical Sciences Source Type: research

Association of Breakfast Intake With Incident Stroke and Coronary Heart Disease: The Japan Public Health Center-Based Study Clinical Sciences
Conclusions— The frequency of breakfast intake was inversely associated with the risk of stroke, especially cerebral hemorrhage in Japanese, suggesting that eating breakfast everyday may be beneficial for the prevention of stroke.
Source: Stroke - January 25, 2016 Category: Neurology Authors: Kubota, Y., Iso, H., Sawada, N., Tsugane, S., The JPHC Study Group Tags: Cardiovascular Disease, Epidemiology, Primary Prevention, Risk Factors Clinical Sciences Source Type: research

Midlife Orthostatic Hypotension May Increase Risk of Dementia, Stroke
People with orthostatic hypotension (an excessive drop in blood pressure when standing up that can lead to dizziness and fainting) in midlife may be more likely than those without the condition to develop stroke and dementia later in life, according to astudy inNeurology.“The presence of orthostasis, especially in midlife, might identify individuals in whom more careful monitoring or risk factor management might be warranted,” wrote lead author Andreea Rawlings, Ph.D., of the Johns Hopkins Bloomberg School of Public Health and colleagues.These findings come from an analysis of data from 11,709 participants without a hi...
Source: Psychiatr News - July 30, 2018 Category: Psychiatry Tags: Alzheimer's Alzheimer's risk factors dementia dizziness orthostatic hypotension stroke Source Type: research

Acute Psychological Stress is a Trigger for Stroke: A Case-Crossover Study
Conventional risk factors for stroke that have been identified are mostly chronic diseases that explain much of the variation as to who develops stroke. However, these risk factors do not equip us with the means to predict when an event like stroke will occur. It has been observed that acute events like stroke and coronary heart disease are preceded by episodes of acute stress. The present study was undertaken to determine whether acute psychological stress is a potential triggering factor for the occurrence of stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - April 1, 2020 Category: Neurology Authors: Manya Prasad, Pardeep Khanna, V.K. Katyal, Ramesh Verma Source Type: research

Predictors of Recurrent Ischemic Stroke in Obese Patients With Type 2 Diabetes Mellitus: A Population-based Study
Each year, approximately 0.8 million people are estimated to experience a new or recurrent stroke, according to the 2019 report of the American Heart Association.1 In Malaysia, stroke is the third leading cause of death after ischemic heart disease (IHD) and pneumonia.2 Both obesity and diabetes are considered as the established independent risk factors for ischemic stroke.3 Type 2 diabetes mellitus (T2DM) was also found to be associated with an increase in all-cause as well as cardiovascular mortality following the stroke,4,5 and in a meta-analysis of 18 studies, patients with diabetes had a higher stroke recurrence as co...
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2020 Category: Neurology Authors: Orwa Albitar, Sabariah Noor Harun, Nur Ezzati Abidin, Balamurugan Tangiisuran, Hadzliana Zainal, Irene Looi, Khairul Azmi Ibrahim, Norsima Nazifah Sidek, Keat Wei Loo, Keng Yee Lee, Zariah Abdul Aziz, Siti Maisharah Sheikh Ghadzi Source Type: research

Analysis of microRNA signatures in ischemic stroke thrombus
Conclusions The microRNA expression pattern can provide information regarding the mechanism of stroke by reflecting the underlying pathological status of the organ from which the thrombus was derived.
Source: Journal of NeuroInterventional Surgery - April 12, 2022 Category: Neurosurgery Authors: Kim, J.-M., Byun, J.-S., Kim, J., Park, M.-S., Hong, S. A., Nam, T.-K., Choi, H. H., Hong, S., Han, S.-H., Jeong, H.-B., Park, K.-Y., Kim, H. R. Tags: Ischemic stroke Source Type: research

Clopidogrel Use Is Associated With an Increased Prevalence of Cerebral Microbleeds in a Stroke-Free Population: The Rotterdam Study Stroke
Conclusions In stroke-free individuals, clopidogrel use was associated with a higher prevalence and higher number of CMBs. Whether this association is causal requires confirmation in prospective studies, especially given the small number of participants taking clopidogrel and the possibility of residual confounding in this study.
Source: JAHA:Journal of the American Heart Association - September 26, 2013 Category: Cardiology Authors: Darweesh, S. K. L., Leening, M. J. G., Akoudad, S., Loth, D. W., Hofman, A., Arfan Ikram, M., Vernooij, M. W., Stricker, B. H. Tags: Stroke Source Type: research

Haemorrhagic stroke in term and late preterm neonates
Conclusions In our cohort with acute HS, most presented with seizures, apnoea and/or poor feeding. Fetal distress and CHD were common. Nearly two-thirds had intraparenchymal with intraventricular haemorrhage. Over half were due to haemorrhagic transformation of infarction. Short-term neurologic deficits were present in 47% of survivors.
Source: Archives of Disease in Childhood - Fetal and Neonatal Edition - December 13, 2013 Category: Perinatology & Neonatology Authors: Bruno, C. J., Beslow, L. A., Witmer, C. M., Vossough, A., Jordan, L. C., Zelonis, S., Licht, D. J., Ichord, R. N., Smith, S. E. Tags: Epidemiologic studies, Congenital heart disease, Drugs: cardiovascular system, Drugs: CNS (not psychiatric), Epilepsy and seizures, Hydrocephalus, Stroke, Pregnancy, Child health Original articles Source Type: research

Cardiovascular Health Status and Metabolic Syndrome in Ecuadorian Natives/Mestizos Aged 40 Years or More with and without Stroke and Ischemic Heart Disease—An Atahualpa Project Case–Control Nested Study
Conclusions: This case–control study suggests that none of the measured risk factors is associated with the occurrence of vascular events. It is possible that some yet unmeasured risk factors or an unknown genetic predisposition may account for a sizable proportion of stroke and ischemic heart disease occurring in the native/mestizo population of rural coastal Ecuador.
Source: Journal of Stroke and Cerebrovascular Diseases - July 8, 2013 Category: Neurology Authors: Oscar H. Del Brutto, Robertino M. Mera, Martha Montalván, Victor J. Del Brutto, Mauricio Zambrano, Milton Santamaría, Daniel Tettamanti Tags: Original Articles Source Type: research