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Lifetime direct costs of stroke for indigenous patients adjusted for comorbidities
Conclusions: The costs of stroke for indigenous people and patients with different comorbidities are substantial and an integrated prevention strategy is needed.
Source: Neurology - July 31, 2016 Category: Neurology Authors: Zhao, Y., Condon, J., Lawton, P., He, V., Cadilhac, D. A. Tags: Cost effectiveness/economic, All Cerebrovascular disease/Stroke, Cohort studies ARTICLE Source Type: research

Gender differences in the age‐stratified prevalence of risk factors in Korean ischemic stroke patients: a nationwide stroke registry‐based cross‐sectional study
ConclusionKorean women with stroke had more hypertension and hyperlipidemia after middle age, more diabetes after 65 years, and more atrial fibrillation throughout all ages. Strategies to control risk factors in women at risk for stroke are eagerly needed.
Source: International Journal of Stroke - October 22, 2013 Category: Neurology Authors: Tai Hwan Park, Youngchai Ko, Soo Joo Lee, Kyung Bok Lee, Jun Lee, Moon‐Ku Han, Jong‐Moo Park, Dong‐Eog Kim, Yong‐Jin Cho, Keun‐Sik Hong, Joon‐Tae Kim, Ki‐Hyun Cho, Dae‐Hyun Kim, Jae‐Kwan Cha, Kyung‐Ho Yu, Byung‐Chul Lee, Byung‐Woo Tags: Research Source Type: research

Predictors of Noticing Stroke Educational Campaign
Conclusions: Tobacco smokers in particular should be targeted by stroke awareness campaigns, for example, through health warning labels on cigarette packs. People with some stroke risk factors, such as heart disease and obesity, are responsive to information about stroke. Therefore, educational campaigns should target the groups with increased risk of stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - April 11, 2014 Category: Neurology Authors: Petra Sobotková, David Goldemund, Michal Reif, Robert Mikulík Tags: Original Articles Source Type: research

Neighborhood socioeconomic status and the prevalence of stroke and coronary heart disease in rural China: A population‐based study
ConclusionsThere were differences in vascular risk across rural villages in China, with higher lifetime stroke and CHD prevalence in higher‐income villages. For CHD, neighborhood effects were stronger among younger residents of high‐income villages. The results may have implications for public health interventions targeting populations at risk.
Source: International Journal of Stroke - August 4, 2014 Category: Neurology Authors: Xun Tang, Daniel T. Laskowitz, Liu He, Truls Østbye, Janet Prvu Bettger, Yang Cao, Na Li, Jingrong Li, Zongxin Zhang, Jianjiang Liu, Liping Yu, Haitao Xu, Yonghua Hu, Larry B. Goldstein Tags: Research Source Type: research

Distribution of risk factors differs from coronary heart disease and stroke in China: a national population survey
Conclusions The distribution of risk factors for CHD and stroke were substantial differences. More specific prevention and control measures should be formulated according to the distribution differences of risk factors related to CVD.
Source: BMJ Open - November 24, 2022 Category: General Medicine Authors: Li, Y., Yin, L., Shen, Y., Wang, A., Zhou, L., Gao, Y., Li, Y., Lu, J., Shi, S., Tian, C., Xu, Y., Wang, L., on behalf of the China National Stroke Screening Survey investigators Tags: Open access, Public health Source Type: research

The China Stroke Secondary Prevention Trial (CSSPT) protocol: a double‐blinded, randomized, controlled trial of combined folic acid and B vitamins for secondary prevention of stroke
DiscussionThis is the first multicenter randomized trial of secondary prevention for ischemic stroke in a Chinese population with a higher homocysteine level but without folate food fortification.
Source: International Journal of Stroke - March 12, 2013 Category: Neurology Authors: Xuedong Liu, Ming Shi, Feng Xia, Junliang Han, Zhirong Liu, Bo Wang, Fang Yang, Li Li, Songdi Wu, Ling Wang, Nan Liu, Yali Lv, Gang Zhao Tags: Protocols Source Type: research

Serum Fatty Acids and Incidence of Ischemic Stroke Among Postmenopausal Women Clinical Sciences
Conclusions— These findings suggest that individual serum trans, saturated, and monounsaturated fatty acids are positively associated with particular ischemic stroke subtypes, whereas individual n3 and n6 polyunsaturated fatty acids are inversely associated.
Source: Stroke - September 23, 2013 Category: Neurology Authors: Yaemsiri, S., Sen, S., Tinker, L. F., Robinson, W. R., Evans, R. W., Rosamond, W., Wasserthiel-Smoller, S., He, K. Tags: Epidemiology Clinical Sciences Source Type: research

Herpes zoster as a risk factor for stroke and TIA: A retrospective cohort study in the UK
Conclusion: HZ is an independent risk factor for vascular disease in the UK population, particularly for stroke, TIA, and MI in subjects affected before the age of 40 years. In older subjects, better ascertainment of vascular risk factors and earlier intervention may explain the reduction in risk of stroke after the occurrence of HZ.
Source: Neurology - January 20, 2014 Category: Neurology Authors: Breuer, J., Pacou, M., Gauthier, A., Brown, M. M. Tags: Stroke in young adults, Viral infections, All Cerebrovascular disease/Stroke, Cohort studies, Risk factors in epidemiology ARTICLE Source Type: research

Subclinical cardiac dysfunction increases the risk of stroke and dementia: The Rotterdam Study
Conclusions: In elderly free of clinical cardiac disease, worse diastolic function is associated with clinical stroke, dementia, and silent infarcts on MRI, whereas worse systolic function is related only to clinical stroke. These findings can form the basis for future research on the utility of cardiac function as potential intervention target for prevention of neurologic diseases.
Source: Neurology - February 23, 2015 Category: Neurology Authors: de Bruijn, R. F. A. G., Portegies, M. L. P., Leening, M. J. G., Bos, M. J., Hofman, A., van der Lugt, A., Niessen, W. J., Vernooij, M. W., Franco, O. H., Koudstaal, P. J., Ikram, M. A. Tags: MRI, All Cerebrovascular disease/Stroke, All Cognitive Disorders/Dementia, Cohort studies ARTICLE Source Type: research

Mechanisms and Outcomes of Ischemic Stroke in Pregnancy and Postpartum: A Retrospective Cross-Sectional Study (P3.070)
CONCLUSIONS: Women with pregnancy-associated ischemic strokes were younger and had fewer vascular risk factors when compared with other young women with ischemic strokes. Outcomes were similar in the two groups, with a substantial proportion of poor outcomes in both groups. Our results are limited by the small sample size and retrospective nature of the study. Larger studies are needed to better characterize the pathophysiology of pregnancy-associated stroke.Disclosure: Dr. Miller has nothing to disclose. Dr. Yaghi has nothing to disclose. Dr. Boehme has nothing to disclose. Dr. Willey has nothing to disclose. Dr. Elkind h...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Miller, E., Yaghi, S., Boehme, A., Willey, J., Elkind, M., Marshall, R. Tags: Cerebrovascular Disease and Interventional Neurology: Ischemic Stroke Outcome Source Type: research

FDA strengthens warning that NSAIDs increase heart attack and stroke risk
Back in 2005, the FDA warned that taking nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen and naproxen increased the risk of having a heart attack or stroke. Last week it took the unusual step of further strengthening this warning. This was done on the advice of an expert panel that reviewed new information about NSAIDs and their risks. Because NSAIDs are widely used, it’s important to be aware of downsides of taking an NSAID and to take steps to limit the risk. Many people take NSAIDs to relieve mild to moderate pain. These medications may be particularly effective in conditions in which pain results pri...
Source: New Harvard Health Information - July 13, 2015 Category: Consumer Health News Authors: Gregory Curfman, MD Tags: Heart Health heart attack heart disease NSAIDS Stroke Source Type: news

CYP2C19 Loss-of-Function Associated with First-Time Ischemic Stroke in Non-surgical Asymptomatic Carotid Artery Stenosis During Clopidogrel Therapy
This study measures effect ofCYP2C19 genotype on ischemic stroke risk during clopidogrel therapy for asymptomatic, extracranial carotid stenosis patients. Using deidentified electronic health records, patients were selected for retrospective cohort using administrative code for carotid stenosis, availability ofCYP2C19 genotype result, clopidogrel exposure, and established patient care. Patients with intracranial atherosclerosis, aneurysm, arteriovenous malformation, prior ischemic stroke, or observation time<1 month were excluded. Dual antiplatelet therapy patients were included. Patients with carotid endarterectomy or ...
Source: Translational Stroke Research - February 21, 2021 Category: Neurology Source Type: research

Stroke prevention in the Stroke Belt: Is the adolescence period the clue?
Early prevention of diseases is crucial for public health, especially for stroke and heart disease, the leading causes of morbidity and mortality in the United States. Global geographic disparities in stroke incidence and mortality are substantial. In the United States, residents of the southeastern states endure higher stroke mortality than other regions.1 Many theories have attempted to explain the excess burden of stroke in this Stroke Belt (SB) without convincing explanations.
Source: Neurology - April 29, 2013 Category: Neurology Authors: Castilla-Guerra, L., Mokdad, A. H. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Cohort studies, Incidence studies, Risk factors in epidemiology EDITORIALS Source Type: research

Low Dehydroepiandrosterone Sulfate is Associated With Increased Risk of Ischemic Stroke Among Women Clinical Sciences
Conclusions— Lower DHEAS levels were associated with a greater risk of ischemic stroke, even after adjustment for potential confounders. These novel observations warrant confirmation in other populations.
Source: Stroke - June 24, 2013 Category: Neurology Authors: Jimenez, M. C., Sun, Q., Schurks, M., Chiuve, S., Hu, F. B., Manson, J. E., Rexrode, K. M. Tags: Acute Cerebral Infarction, Epidemiology Clinical Sciences Source Type: research

Improving the Prediction of Stroke or Death After Transient Ischemic Attack (TIA) by Adding Diffusion-weighted Imaging Lesions and TIA Etiology to the ABCD2 Score
The present study investigated the addition of transient ischemic attack (TIA) etiology and diffusion-weighted imaging (DWI) to the ABCD2 score, creating the ABCDE+ score, to improve the predictive ability of stroke risk or death at 6 months after TIA. We performed a cohort study of 150 consecutive patients with TIA. All patients underwent DWI and all had an etiologic workup and were followed up for 6 months. The area under the receiver operating characteristic curve (AUC) was used to compare the scores' ability to predict the outcome of stroke or death. Multivariate Cox regression analysis was performed to evaluate the as...
Source: Journal of Stroke and Cerebrovascular Diseases - May 21, 2012 Category: Neurology Authors: Ali Arhami Dolatabadi, Amirhosein Meisami, Hamidreza Hatamabadi, Behnam Mansori, Ali Shahrami, Afshin Amini, Kazem Jamali Tags: Original Articles Source Type: research