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Total 8256 results found since Jan 2013.

Meta-analysis finds benefit for dual antiplatelet therapy but limitations preclude changing standard mono antiplatelet therapy approach for acute non-cardioembolic ischaemic stroke or transient ischaemic attack
Commentary on: Wong KSL, Wang Y, Leng X, et al.. Early dual versus mono antiplatelet therapy for acute non-cardioembolic ischemic stroke or transient ischemic attack. An updated systematic review and meta-analysis. Circulation 2013;128:1656–66. Context Current guidelines recommend aspirin, aspirin plus clopidogrel or aspirin plus extended-release dipyridamole for treatment of acute ischaemic stroke (IS) or transient ischaemic attack (TIA) to prevent recurrent stroke, myocardial infarction and cardiovascular death.1 The Clopidogrel in High-risk patients with Acute Non-disabling Cerebrovascular Events (CHANCE) trial ra...
Source: Evidence-Based Medicine - May 19, 2014 Category: Internal Medicine Authors: Aronow, W. S. Tags: Clinical trials (epidemiology), Epidemiologic studies, Drugs: cardiovascular system, Stroke, Ischaemic heart disease Therapeutics Source Type: research

Biomarkers and Mortality After Transient Ischemic Attack and Minor Ischemic Stroke: Population-Based Study Clinical Sciences
Conclusions— Several biomarkers predicted death of any cause after transient ischemic attack and minor stroke. N-terminal pro-B-type natriuretic peptide and heart-type fatty-acid-binding protein might improve patient selection for additional screening for occult cardiac disease or cancer, respectively. However, our results require validation in future studies.
Source: Stroke - February 23, 2015 Category: Neurology Authors: Greisenegger, S., Segal, H. C., Burgess, A. I., Poole, D. L., Mehta, Z., Rothwell, P. M. Tags: Epidemiology Clinical Sciences Source Type: research

Pathogenesis and Risk Factors for Cerebral Infarct After Surgical Aortic Valve Replacement Brief Reports
Conclusions— The principal mechanism of acute cerebral infarction after aortic valve replacement is embolism. There are distinct factors associated with watershed and embolic infarct, some of which may be modifiable.
Source: Stroke - July 24, 2016 Category: Neurology Authors: Massaro, A., Messe, S. R., Acker, M. A., Kasner, S. E., Torres, J., Fanning, M., Giovannetti, T., Ratcliffe, S. J., Bilello, M., Szeto, W. Y., Bavaria, J. E., Mohler, E. R., Floyd, T. F., for the Determining Neurologic Outcomes From Valve Operations (DeNO Tags: Valvular Heart Disease, Magnetic Resonance Imaging (MRI), Cardiovascular Surgery, Cerebrovascular Disease/Stroke, Ischemic Stroke Brief Reports Source Type: research

PCSK9 Loss-of-Function Variants, Low-Density Lipoprotein Cholesterol, and Risk of Coronary Heart Disease and Stroke: Data From 9 Studies of Blacks and Whites Original Articles
Conclusions— PCSK9 LOF variants were associated with lower LDL-C and coronary heart disease incidence. PCSK9 LOF variants were not associated with stroke risk.
Source: Circulation: Cardiovascular Genetics - August 2, 2017 Category: Cardiology Authors: Kent, S. T., Rosenson, R. S., Avery, C. L., Chen, Y.-D. I., Correa, A., Cummings, S. R., Cupples, L. A., Cushman, M., Evans, D. S., Gudnason, V., Harris, T. B., Howard, G., Irvin, M. R., Judd, S. E., Jukema, J. W., Lange, L., Levitan, E. B., Li, X., Liu, Tags: Lipids and Cholesterol, Genetic, Association Studies, Myocardial Infarction, Meta Analysis, Cerebrovascular Disease/Stroke Original Articles Source Type: research

Association of serum uric acid with risk of stroke in US adults: A cross-sectional study from NHANES 1999 –2020
Stroke is the second-most global death cause, only after ischemic heart disease, and third-most contributor to disability1, making it a major therapeutic challenge. More than 100 million individuals worldwide experience stroke every year, of which 795,000 cases are in the United States.2 Therefore, improved preventive strategies are needed; particularly, strategies targeting the modifiable risk factors of stroke, such as hypertension, hyperglycemia, and dyslipidemia, may help prevent more than approximately 90% of stroke cases.
Source: Journal of Stroke and Cerebrovascular Diseases - June 3, 2023 Category: Neurology Authors: Bei Gao, Yun Bao, Min Meng, Lijun Yu, Yali Lu, Rina Sa, Xiaoyan Liang, Jie Shi Source Type: research

Association of underlying untreated cardiovascular risk factors with mortality and functional outcome in ischaemic stroke patients
Stroke is the third leading cause of death after ischaemic heart disease (IHD) and pneumonia in Malaysia.1 Aziz et al. reported that Malaysia's prevalence of ischaemic stroke had increased from 42.8 to 118.7 in 100,000 from 2010 to 2014. The report showed that 8-11% of ischaemic stroke patients died within 30 days while 56-61% survived with significant disability in Malaysia.2 Our previous study showed that patients with ischaemic stroke in Malaysia were younger, but the mortality rate was higher than in other countries.
Source: Journal of Stroke and Cerebrovascular Diseases - July 19, 2023 Category: Neurology Authors: Teck Long King, Lee Len Tiong, Zariah Abdul  Aziz, Wan Chung Law Source Type: research

Comparison of Baseline Heart Rate Variability in Stable Ischemic Heart Disease Patients with and without Stroke in Long-Term Observation
Decreased heart rate variability (HRV) has predictive value in postinfarction as well as in ischemic stroke patients. However, it is unknown if ischemic heart disease (IHD) patients who are at high risk of stroke have different HRV profile. The goal of this study was to compare baseline HRV (traditional and novel indices) in stable IHD patients with and without stroke in long-term observation.
Source: Journal of Stroke and Cerebrovascular Diseases - August 7, 2016 Category: Neurology Authors: Micha ł Kuzemczak, Paulina Białek-Ławniczak, Katarzyna Torzyńska, Agnieszka Janowska-Kulińska, Izabela Miechowicz, Lucyna Kramer, Jerzy Moczko, Tomasz Siminiak Source Type: research

Vegetarians May Be At Higher Risk Of Stroke, Study Finds
BOSTON (CBS) – Many people adopt a vegetarian lifestyle to help reduce their risk of cardiovascular disease, but a new study published in the BMJ finds people who avoid meat all together may be at a higher risk of stroke. Researchers in the U.K. looked at about 48 thousand adults over 18 years. They found that vegetarians, vegans, and pescatarians (people who eat fish but not meat) had a lower risk of ischemic heart disease, like heart attacks. But vegetarians had a 20% higher risk of stroke compared to meat eaters. It’s not clear why vegetarians may suffer more strokes. Perhaps it is due to lower levels of cer...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - September 5, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Healthwatch Syndicated Local Dr. Mallika Marshall Stroke Vegetarian Source Type: news

Vitamin B may reduce risk of stroke
Researchers have uncovered evidence that suggests vitamin B supplements could help to reduce the risk of stroke, according to a study published in the journal Neurology. Vitamin B supplements are said to be beneficial for many health issues, including stress, anxiety, depression, dementia, Alzheimer's disease and heart disease. However, according to Xu Yuming of Zhengzhou University in Zhengzhou, China, previous studies have conflicting findings regarding the use of vitamin B supplements and stroke or heart attack...
Source: Health News from Medical News Today - September 19, 2013 Category: Consumer Health News Tags: Stroke Source Type: news

Stroke risks increase with high levels of anxiety
The negative health effects of anxiety, such as increased coronary heart disease risks, have long been documented and accepted in the medical community. But now, research suggests that individuals with high levels of anxiety have an increased risk for stroke.The researchers, who are from the University of Pittsburgh, published the results of their study in the journal Stroke.They say that anxiety disorders - characterized by fear, unease and worry - impact nearly 20% of US adults each year and often last for at least 6 months.
Source: Health News from Medical News Today - December 22, 2013 Category: Consumer Health News Tags: Stroke Source Type: news

Predictors of Mortality in Patients With Lacunar Stroke in the Secondary Prevention of Small Subcortical Strokes Trial Clinical Sciences
Conclusions— Unexpected interactions between assigned antiplatelet therapy and each of ischemic heart disease and normal/prehypertensive status accounted for increased mortality among patients with recent lacunar stroke given dual antiplatelet therapy. Despite extensive exploratory analyses, the mechanisms underlying these interactions are uncertain. Clinical Trial Registration— URL: http://www.SPS3ClinicalTrials.gov. Unique identifier: NCT00059306.
Source: Stroke - September 22, 2014 Category: Neurology Authors: Sharma, M., Pearce, L. A., Benavente, O. R., Anderson, D. C., Connolly, S. J., Palacio, S., Coffey, C. S., Hart, R. G. Tags: Cerebral Lacunes, Antiplatelets Clinical Sciences Source Type: research

Large-Scale Phenome-Wide Association Study of PCSK9 Variants Demonstrates Protection Against Ischemic Stroke Original Articles
Conclusions: This result represents the first genetic evidence in a large cohort for the protective effect of PCSK9 inhibition on ischemic stroke and corroborates exploratory evidence from clinical trials. PCSK9 inhibition was not associated with variables other than those related to LDL (low-density lipoprotein) cholesterol, atherosclerosis, and type 2 diabetes mellitus, suggesting that other effects are either small or absent.
Source: Circulation: Cardiovascular Genetics - July 11, 2018 Category: Cardiology Authors: Rao, A. S., Lindholm, D., Rivas, M. A., Knowles, J. W., Montgomery, S. B., Ingelsson, E. Tags: Cardiovascular Disease, Diabetes, Type 2, Genetic, Association Studies, Ischemic Stroke Original Articles Source Type: research

Supermarket trolley sensors could help to identify risk of stroke, say scientists
Study with 2,155 participants at Sainsbury ’s stores leads to atrial fibrillation diagnosis for 39 people unaware they had conditionSupermarket trolleys may be known for their wonky wheels and rusty frames, but researchers say the carts could be used to save lives by helping to identify people at risk of stroke through sensors in their handles.According to the British Heart Foundation, one in 45 people in the UK are living with atrial fibrillation (AF), which causes an abnormal heart rhythm and can increase the risk of stroke. While people may be unaware they have the condition, early detection and diagnosis is important...
Source: Guardian Unlimited Science - June 23, 2023 Category: Science Authors: Nicola Davis Science corespondent Tags: Stroke Supermarkets Health Heart disease Medical research Science Society Source Type: news

Coronary Heart Disease And History Of Stroke A Fatal Combination
The cardiology service team at the Hopital Bichat and the Mixed INSERM Unit 698 (AP-HP, Universite Paris Diderot), in collaboration with international teams of researchers, studied a cohort of patients suffering from coronary disease. The study showed that those patients with a history of stroke or transient ischæmic attack (TIA) are not only at higher risk of cardio-vascular episodes but also of haemorrhagic events, stressing the therapeutic challenge involved in treating such patients. The research is published online in Circulation...
Source: Health News from Medical News Today - February 21, 2013 Category: Consumer Health News Tags: Stroke Source Type: news

Living near airport could raise stroke risk
People who suffer through overnight aircraft noise are at greater risk of heart disease and stroke, study finds    
Source: Telegraph Health - March 1, 2014 Category: Consumer Health News Tags: aircraft noise environmental health night stroke heart disease Source Type: news