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Total 8256 results found since Jan 2013.

Relationship of Preexisting Cardiovascular Comorbidities to Newly Diagnosed Atrial Fibrillation After Ischemic Stroke Brief Report
Conclusions—Preexisting cardiovascular comorbidities underlie AF newly diagnosed after stroke. Consequently, these high-risk patients should be closely monitored for incident AF to facilitate an earlier diagnosis of AF and avoid stroke with appropriate thromboprophylaxis.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Arnaud Bisson, Nicolas Clementy, Alexandre Bodin, Denis Angoulvant, Dominique Babuty, Gregory Y.H. Lip, Laurent Fauchier Tags: Atrial Fibrillation, Ischemic Stroke Brief Reports Source Type: research

Association of Osteopontin, Neopterin, and Myeloperoxidase With Stroke Risk in Patients With Prior Stroke or Transient Ischemic Attacks Clinical Sciences
Background and Purpose—Established risk factors do not fully identify patients at risk for recurrent stroke. The SPARCL trial (Stroke Prevention by Aggressive Reduction in Cholesterol Levels) evaluated the effect of atorvastatin on stroke risk in patients with a recent stroke or transient ischemic attack and no known coronary heart disease. This analysis explored the relationships between 13 plasma biomarkers assessed at trial enrollment and the occurrence of outcome strokes.Methods—We conducted a case–cohort study of 2176 participants; 562 had outcome strokes and 1614 were selected randomly from those without outcom...
Source: Stroke - November 27, 2017 Category: Neurology Authors: Peter Ganz, Pierre Amarenco, Larry B. Goldstein, Henrik Sillesen, Weihang Bao, Gregory M. Preston, K. Michael A. Welch Tags: Biomarkers, Proteomics, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Coronary Artery Calcification, Intima-Media Thickness, and Ankle-Brachial Index Are Complementary Stroke Predictors Clinical Sciences
Conclusions— CAC, CIMT, and ABI provide complementary information about stroke risk. ABI, which is distinctive in a small subpopulation, had the highest and CIMT, which is distributed across a larger range of values, had the lowest predictive value.
Source: Stroke - August 25, 2014 Category: Neurology Authors: Gronewold, J., Bauer, M., Lehmann, N., Mahabadi, A. A., Kalsch, H., Weimar, C., Berger, K., Moebus, S., Jockel, K.-H., Erbel, R., Hermann, D. M., on behalf of the Heinz Nixdorf Recall Study Investigative Group Tags: Imaging, Computerized tomography and Magnetic Resonance Imaging, Doppler ultrasound, Transcranial Doppler etc., Risk Factors for Stroke Clinical Sciences Source Type: research

Stroke and Circulating Extracellular RNAs Clinical Sciences
Conclusions—This is the largest study of ex-RNAs in relation to stroke using an unbiased approach in an observational cohort and the first large study to examine human small noncoding RNAs beyond miRNAs. These results demonstrate that when studied in a large observational cohort, extracellular miRNAs are associated with stroke risk.
Source: Stroke - March 27, 2017 Category: Neurology Authors: Eric Mick, Ravi Shah, Kahraman Tanriverdi, Venkatesh Murthy, Mark Gerstein, Joel Rozowsky, Robert Kitchen, Martin G. Larson, Daniel Levy, Jane E. Freedman Tags: Gene Expression & Regulation, Ischemic Stroke Original Contributions Source Type: research

High-intensity interval training in stroke rehabilitation.
The objectives of this narrative review are to (1) propose a framework for categorizing HIT protocols; (2) summarize the safety and effectiveness evidence of HIT among healthy adults and people with heart disease and stroke; (3) discuss theoretical mechanisms, protocol selection, and safety considerations for poststroke HIT; and (4) provide directions for future research. PMID: 23893831 [PubMed - in process]
Source: Topics in Stroke Rehabilitation - July 1, 2013 Category: Neurology Authors: Boyne P, Dunning K, Carl D, Gerson M, Khoury J, Kissela B Tags: Top Stroke Rehabil Source Type: research

Effect of High-Dose Atorvastatin on Renal Function in Subjects With Stroke or Transient Ischemic Attack in the SPARCL Trial Clinical Sciences
Conclusions— This post hoc analysis suggests that atorvastatin treatment may improve renal function in patients with prior stroke or transient ischemic attack with and without chronic kidney disease, and that atorvastatin treatment may prevent eGFR decline in patients with stroke and diabetes mellitus. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00147602.
Source: Stroke - September 22, 2014 Category: Neurology Authors: Amarenco, P., Callahan, A., Campese, V. M., Goldstein, L. B., Hennerici, M. G., Messig, M., Sillesen, H., Welch, K. M. A., Wilson, D. J., Zivin, J. A. Tags: Lipids, Secondary prevention, Cerebrovascular disease/stroke Clinical Sciences Source Type: research

Carotid Atherosclerotic Plaque Characteristics on Magnetic Resonance Imaging Relate With History of Stroke and Coronary Heart Disease Clinical Sciences
Conclusions— Whereas carotid plaque thickness and stenosis are associated with the history of ischemic stroke and CHD, carotid intraplaque hemorrhage is associated with ischemic stroke, but not with CHD, providing novel insights into the pathogenesis of cardiovascular events.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Selwaness, M., Bos, D., van den Bouwhuijsen, Q., Portegies, M. L. P., Ikram, M. A., Hofman, A., Franco, O. H., van der Lugt, A., Wentzel, J. J., Vernooij, M. W. Tags: Cardiovascular Disease, Epidemiology, Magnetic Resonance Imaging (MRI), Ischemic Stroke, Atherosclerosis Clinical Sciences Source Type: research

Functional Gain After Inpatient Stroke Rehabilitation: Correlates and Impact on Long-Term Survival Brief Reports
Conclusions— Several factors are independently associated with functional gain after SR. Our findings strongly suggest that the magnitude of functional improvement is a powerful predictor of long-term mortality in patients admitted for SR.
Source: Stroke - September 28, 2015 Category: Neurology Authors: Scrutinio, D., Monitillo, V., Guida, P., Nardulli, R., Multari, V., Monitillo, F., Calabrese, G., Fiore, P. Tags: Other Stroke Treatment - Medical Brief Reports Source Type: research

Rheumatic Mitral Valve Disease Is Associated With Worse Outcomes in Stroke Clinical Sciences
We examined the association between RMVD and both serious and common cardiovascular and noncardiovascular (respiratory and infective) complications in a cohort of hospitalized stroke patients based in Thailand. Factors associated with in-hospital mortality were also explored. Data were obtained from a National Insurance Database. All hospitalized strokes between October 1, 2004, and January 31, 2013, were included in the current study. Characteristics and outcomes were compared for RMVD and non-RMVD patients. Logistic regression, propensity score matching, and multivariate models were used to assess study outcomes.Results...
Source: Stroke - October 23, 2016 Category: Neurology Authors: Wood, A. D., Mannu, G. S., Clark, A. B., Tiamkao, S., Kongbunkiat, K., Bettencourt-Silva, J. H., Sawanyawisuth, K., Kasemsap, N., Barlas, R. S., Mamas, M., Myint, P. K. Tags: Rheumatic Heart Disease, Valvular Heart Disease, Complications, Mortality/Survival, Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Takotsubo-Like Myocardial Dysfunction in Ischemic Stroke Clinical Sciences
This study included 23 patients (0.42%). The mean age was 70.7±13.9 years, with predominance of women (73.9%) and typical pattern of Takotsubo-like myocardial dysfunction (91.3%). They were associated with short-term poor functional outcomes, including high mortality, neurological deterioration, and functional status at discharge, compared with those without (39.1% versus 2.4%, 47.8% versus 7.4%; and median [interquartile range], 5 [5–6] versus 3 [2–4]; all P
Source: Stroke - October 23, 2016 Category: Neurology Authors: Jung, J.-M., Kim, J.-G., Kim, J. B., Cho, K.-H., Yu, S., Oh, K., Kim, Y.-H., Choi, J.-Y., Seo, W.-K. Tags: Risk Factors, Cardiomyopathy, Prognosis, Mortality/Survival, Ischemic Stroke Original Contributions Source Type: research

Direct Mechanical Intervention Versus Bridging Therapy in Stroke Patients Eligible for Intravenous Thrombolysis Clinical Sciences
Background and Purpose—Randomized controlled trials have shown that mechanical thrombectomy (MT) plus best medical treatment improves outcome in stroke patients with large-vessel occlusion in the anterior circulation. Whether direct MT is equally effective as bridging thrombolysis (intravenous thrombolysis plus MT) in intravenous thrombolysis eligible patients remains unclear.Methods—We compared clinical and radiological outcomes at 3 months in 249 bridging patients with 111 patients receiving direct MT for large-vessel occlusion anterior circulation stroke from 2 prospective registries (study period Essen: June 2012 t...
Source: Stroke - November 27, 2017 Category: Neurology Authors: Sebastian Bellwald, Ralph Weber, Tomas Dobrocky, Hannes Nordmeyer, Simon Jung, Jeffrie Hadisurya, Pasquale Mordasini, Marie–Luise Mono, Christian P. Stracke, Hakan Sarikaya, Corrado Bernasconi, Klaus Berger, Marcel Arnold, Rene Chapot, Jan Gralla, U Tags: Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research

Relationship Between Dietary Vitamin D and Deaths From Stroke and Coronary Heart Disease Brief Report
Background and Purpose—There is growing evidence about the importance of vitamin D for cardiovascular health. Therefore, we examined the relationship between dietary vitamin D intake and risk of mortality from stroke and coronary heart disease in Japanese population.Methods—A prospective study encompassing 58 646 healthy Japanese adults (23 099 men and 35 547 women) aged of 40 to 79 years in whom dietary vitamin D intake was determined via a self-administered food frequency questionnaire. The median follow-up period was 19.3 years (1989–2009). The hazard ratios and 95% confidence intervals of mortality were calcu...
Source: Stroke - January 22, 2018 Category: Neurology Authors: Haytham A. Sheerah, Ehab S. Eshak, Renzhe Cui, Hironori Imano, Hiroyasu Iso, Akiko Tamakoshi Tags: Cardiovascular Disease, Diet and Nutrition, Epidemiology, Risk Factors, Cerebrovascular Disease/Stroke Brief Reports Source Type: research

Cause-specific Mortality after Stroke: Relation to Age, Sex, Stroke Severity, and Risk Factors in a 10-Year Follow-up Study
We investigated cause-specific mortality in relation to age, sex, stroke severity, and cardiovascular risk factor profile in the Copenhagen Stroke Study cohort with 10 years of follow-up. In a Copenhagen community, all patients admitted to the hospital with stroke during 1992-1993 (n = 988) were registered on admission. Evaluation included stroke severity, computed tomography scan, and a cardiovascular risk profile. Cause of death within 10 years according to death certificate information was classified as stroke, heart/arterial disease, or nonvascular disease. Competing-risks analyses were performed by cause-specific Co...
Source: Journal of Stroke and Cerebrovascular Diseases - May 14, 2012 Category: Neurology Authors: Ulla Brasch Mogensen, Tom Skyhøj Olsen, Klaus Kaae Andersen, Thomas Alexander Gerds Tags: Original Articles Source Type: research

Risk factors for ischemic stroke and its subtypes in Chinese vs. Caucasians: Systematic review and meta‐analysis
ConclusionOur study showed a lower prevalence of atrial fibrillation, ischemic heart disease and hypercholesterolemia in Chinese, and mostly similar risk factor associations in Chinese and Caucasian ischemic stroke patients. Further analyses of individual patient data to allow adjustment for confounders are needed to confirm and extend these findings.
Source: International Journal of Stroke - April 23, 2015 Category: Neurology Authors: Chung‐Fen Tsai, Niall Anderson, Brenda Thomas, Cathie L. M. Sudlow Tags: Systematic Review Source Type: research

Differences in the role of black race and stroke risk factors for first vs recurrent stroke
Conclusion: The association of age and black race differs substantially on first vs recurrent stroke risk, with risk factors playing a similar role.
Source: Neurology - February 15, 2016 Category: Neurology Authors: Howard, G., Kissela, B. M., Kleindorfer, D. O., McClure, L. A., Soliman, E. Z., Judd, S. E., Rhodes, J. D., Cushman, M., Moy, C. S., Sands, K. A., Howard, V. J. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Cohort studies, Incidence studies, Risk factors in epidemiology ARTICLE Source Type: research