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Condition: Atrial Fibrillation
Infectious Disease: HIV AIDS

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Total 26 results found since Jan 2013.

Evaluating the Effect of a Patient Decision Aid for Atrial Fibrillation Stroke Prevention Therapy.
Conclusion and Relevance: Our PDA was effective for reducing decisional conflict, increasing patient knowledge, eliciting patients' values, and presenting therapy options that aligned with patients' values and preferences. Using the PDA revealed that many patients have therapy preferences different from their currently prescribed treatment. The PDA is a practical and potentially valuable tool to facilitate decision making about stroke prevention therapy for AF. PMID: 30724102 [PubMed - as supplied by publisher]
Source: The Annals of Pharmacotherapy - February 6, 2019 Category: Drugs & Pharmacology Authors: Loewen PS, Bansback N, Hicklin J, Andrade JG, Kapanen AI, Kwan L, Lynd LD, McClean A, MacGillivray J, Salmasi S Tags: Ann Pharmacother Source Type: research

Availability of patient decision aids for stroke prevention in atrial fibrillation: A systematic review
The objective of this review was to examine the existence and accessibility of, as well as select outcomes associated with, published, formally evaluated patient decision aids for stroke prevention in atrial fibrillation. Methods Six databases were searched from inception to March 2016 with a research librarian. Two authors independently reviewed potential articles, selected trials meeting inclusion criteria, and assessed outcome measures. Outcomes included: patient knowledge, involvement, choice, and decisional conflict. Results The search resulted in 666 articles; most were excluded for not examining stroke prevention in...
Source: American Heart Journal - June 3, 2017 Category: Cardiology Source Type: research

Influence of decision ‐aids on oral anticoagulant prescribing among physicians: a randomized trial
ConclusionsRisks could be communicated using decision aids with only one graphic. Showing the risk of stroke at 5 years could increase the prescription of OACs to patients with AF. Faced with the same risk of stroke, physicians prescribed less to themselves than to patients.This article is protected by copyright. All rights reserved.
Source: European Journal of Clinical Investigation - July 6, 2017 Category: General Medicine Authors: Cristian Baicus, Caterina Delcea, Alina Dima, Emilia Oprisan, Ciprian Jurcut, Gheorghe Andrei Dan Tags: Original Paper Source Type: research

Influence of decision aids on oral anticoagulant prescribing among physicians: a randomised trial
ConclusionsRisks could be communicated using decision aids with only one graphic. Showing the risk of stroke at 5 years could increase the prescription of OACs to patients with AF. Faced with the same risk of stroke, physicians prescribed less to themselves than to patients.
Source: European Journal of Clinical Investigation - July 28, 2017 Category: General Medicine Authors: Cristian Baicus, Caterina Delcea, Alina Dima, Emilia Oprisan, Ciprian Jurcut, Gheorghe Andrei Dan Tags: Original Article Source Type: research

Genotype-phenotype associations in atrial fibrillation: meta-analysis
ConclusionsPooled analysis showed a significantly high prevalence of stroke (10%) inRS2200733 AF patients. AF patients with the studied SNPs had preserved left ventricular systolic function (i.e., ejection fraction greater than 50%). AF patients withRS10033464 presented larger left atrium diameter (44  mm (95% CI 42.02–45.98)) than those with other SNPs. The late AF recurrence rate was highest inRS2200733 patients (53% (95% CI 0.43 –0.64)). This study aids our understanding of the existing genetic findings and the function-altering “strongest” SNPs.
Source: Journal of Interventional Cardiac Electrophysiology - November 17, 2018 Category: Cardiology Source Type: research

Ensuring medication adherence with direct oral anticoagulant drugs: Lessons from adherence with vitamin K antagonists (VKAs)
Abstract: Medication adherence (taking drugs properly) is uncommon among patients on warfarin. Poor adherence to warfarin leads to an increase in adverse medical events, including stroke in atrial fibrillation (AF). Factors related to patients, physicians and the health system account for poor adherence. Direct oral anticoagulants (DOACs) are easier to use than warfarin, with fewer drug and food interactions and no need for routine blood monitoring. A proper use of DOACs may reduce the risk of stroke in AF. However, in clinical settings where no laboratory monitoring is needed, a poor medication adherence is common and may...
Source: Thrombosis Research - February 12, 2014 Category: Hematology Authors: Alessandro Di Minno, Gaia Spadarella, Antonella Tufano, Domenico Prisco, Giovanni Di Minno Tags: Mini-Reviews Source Type: research

Educational and behavioural interventions for anticoagulant therapy in patients with atrial fibrillation.
CONCLUSIONS: This review demonstrates that there is insufficient evidence to draw definitive conclusions regarding the impact of educational or behavioural interventions on TTR in AF patients receiving OAT. Thus, more trials are needed to examine the impact of interventions on anticoagulation control in AF patients and the mechanisms by which they are successful. It is also important to explore the psychological implications for patients suffering from this long-term chronic condition. PMID: 28378924 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - April 5, 2017 Category: Journals (General) Authors: Clarkesmith DE, Pattison HM, Khaing PH, Lane DA Tags: Cochrane Database Syst Rev Source Type: research

Predictors of Long-Term Outcomes in Patients with Significant Myxomatous Mitral Regurgitation Undergoing Exercise Echocardiography.
CONCLUSIONS: In patients with ≥III+ myxomatous MR undergoing ExEc, lower %age-gender predicted METS, lower HRR, atrial fibrillation, lower LV ejection fraction and high resting RVSP predicted worse outcomes. PMID: 24396041 [PubMed - as supplied by publisher]
Source: Circulation - January 6, 2014 Category: Cardiology Authors: Naji P, Griffin BP, Asfahan F, Barr TS, Rodriguez LL, Grimm R, Agarwal S, Stewart WJ, Mihaljevic T, Gillinov AM, Desai MY Tags: Circulation Source Type: research

Improving anticoagulation in atrial fibrillation: observational study in three primary care trusts.
CONCLUSIONS: The APEL programme supports improvement in clinical managing AF by a combined programme of education around agreed guidance, computer aids to facilitate decision-making and patient review and feedback of locally identifiable results. If replicated nationally over 3 years, such a programme could result in approximately 1600 fewer strokes every year. PMID: 24771841 [PubMed - in process]
Source: The British Journal of General Practice - May 1, 2014 Category: Primary Care Authors: Robson J, Dostal I, Mathur R, Sohanpal R, Hull S, Antoniou S, Maccallum P, Schilling R, Ayerbe L, Boomla K Tags: Br J Gen Pract Source Type: research

Net Clinical Benefits of Guidelines and Decision Tool Recommendations for Oral Anticoagulant Use among Patients with Atrial Fibrillation
The 2012 American College of Chest Physicians' Evidence-Based Clinical Practice (CHEST), the 2012 European Society of Cardiology, and the 2014 American Heart Association guidelines and published decision tools by LaHaye and Casciano offer oral anticoagulant (OAC) recommendations for patients with atrial fibrillation (AF). The aim of our study was to compare the net clinical benefit (NCB) of OAC prescribing that was concordant with these decision aids.
Source: Journal of Stroke and Cerebrovascular Diseases - October 15, 2015 Category: Neurology Authors: Anand R. Shewale, Jill T. Johnson, Chenghui Li, David Nelsen, Bradley C. Martin Source Type: research

Validation of a patient decision aid for choosing between dabigatran and warfarin for atrial fibrillation.
CONCLUSION: Our DA to allow patients to make an informed decision with their physician regarding dabigatran versus warfarin in AF, proved understandable, comprehensive and helpful. PMID: 24163147 [PubMed - indexed for MEDLINE]
Source: Journal of Population Therapeutics and Clinical Pharmacology - October 26, 2015 Category: Drugs & Pharmacology Tags: J Popul Ther Clin Pharmacol Source Type: research

Cardiac eosinophilic granulomatosis with polyangiitis: rapid imaging with contrast CT and contrast echo aids early diagnosis
A 49-year-old male asthmatic (on Montelukast) with multiple sclerosis presented with shortness of breath and generalised weakness. On examination, he was in cardiac failure with a systolic murmur, rapid atrial fibrillation and weakness in all four limbs with slurred speech. His white cell count was 37x109/L, eosinophils 25x109/L, urea 13.6 mmol/L, creatinine 131 μmol/L, troponin I 4448 ng/L, anti-neutrophil cytoplasmic antibodies (ANCA) weakly positive (negative myeloperoxidase (MPO) and proteinase 3 (PR3)). Differential diagnoses included stroke, myocarditis and eosinophilic granulomatosis with polyangii...
Source: Heart Asia - February 4, 2016 Category: Cardiology Authors: Abraham, D., Freeman, L. J. Tags: Images in cardiovascular medicine Source Type: research

Use of direct oral anticoagulants for treatment of atrial fibrillation in patients with HIV: a review
Purpose of review: Atrial fibrillation is increasingly common in the ageing population. Patients with atrial fibrillation and HIV have a higher stroke risk, with guidelines recommending anticoagulation in the majority. Whilst anticoagulation options have diversified in the last decade for the general population, there is limited evidence for the safety and efficacy of these medications when used concurrently with antiretroviral therapy. We review the potential for patients with HIV on antiretroviral therapy to have direct-acting oral anticoagulations (DOACs). Recent findings: Several case reports have been published in th...
Source: Current Opinion in HIV and AIDS - October 7, 2017 Category: Infectious Diseases Tags: CARDIOVASCULAR DISEASE IN HIV INFECTED PERSONS: Edited by Franck Boccara and Cameron J. Holloway Source Type: research

Association between human immunodeficiency virus serostatus and the prevalence of atrial fibrillation
Atrial fibrillation (AF) leads to increased risk for stroke. Human immunodeficiency virus (HIV) is associated with cardiovascular disease (CVD), although it is unclear if HIV is associated with AF. The purpose of this study was to evaluate the association between HIV serostatus and the prevalence of AF in the Multicenter AIDS Cohort Study. A cross sectional study was conducted among 1674 HIV-infected (HIV+) and uninfected (HIV–) men who completed resting 12-lead electrocardiograms, and/or ambulatory electrocardiogram monitoring. Multivariable logistic regression was used to evaluate the association between AF, defined...
Source: Medicine - July 23, 2021 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research