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Condition: Pain
Therapy: Statin Therapy
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Total 82 results found since Jan 2013.
Use of antidepressants in unipolar depression in the elderly
CONCLUSIONS: Unipolar major depressive episodes in the elderly are frequent and their medicinal treatment has specific features. Knowing the specificities of antidepressant use in the elderly allows to optimize its efficiency and to limit the risk of inappropriate prescription leading to harmful adverse effects.PMID:35153054 | DOI:10.1016/j.encep.2021.11.006
Source: L Encephale - February 14, 2022 Category: Psychiatry Authors: A Pericaud C Straczek F Montastruc M Leboyer A Yrondi C Arbus Source Type: research
Association between CRP/Albumin ratio and long-term mortality in patients with cHronIc Limb-threatening ischemia undergoing EndovaScular therapy Below The Knee: The ACHILES-BTK Registry
CONCLUSIONS: CAR was associated with mortality in CLTI patients undergoing EVT for BTK lesions. CAR may be a simple method to help patient selection, assessment, and intervention strategy for EVT and may improve patient outcomes.PMID:34896550 | DOI:10.1016/j.avsg.2021.11.008
Source: Atherosclerosis - December 13, 2021 Category: Cardiology Authors: Cafer Pan ç Arda G üler İsmail Gürbak Ömer Taşbulak Ahmet G üner Ali Kemal Kalkan Ahmet Arif Yal çın Mehmet Ert ürk Source Type: research
U.S. Task Force Reconsiders Daily Low-Dose Aspirin Use for Preventing Heart Attacks in Adults Over 60
Older adults without heart disease shouldn’t take daily low-dose aspirin to prevent a first heart attack or stroke, an influential health guidelines group said in preliminary updated advice released Tuesday.
Bleeding risks for adults in their 60s and up who haven’t had a heart attack or stroke outweigh any potential benefits from aspirin, the U.S. Preventive Services Task Force said in its draft guidance.
For the first time, the panel said there may be a small benefit for adults in their 40s who have no bleeding risks. For those in their 50s, the panel softened advice and said evidence of benefit is less clear....
Source: TIME: Health - October 12, 2021 Category: Consumer Health News Authors: Lindsey Taylor/AP Tags: Uncategorized healthscienceclimate Research wire Source Type: news
Safety and Efficacy of Perioperative Use of Evolocumab in Myocardial Infarction Patients: Study Protocol for a Multicentre Randomized Controlled Trial
This study aims to evaluate the safety and efficacy of this treatment regimen.MethodsA multicentre, prospective, randomized, controlled superiority trial will be conducted in 530 statin-na ïve MI patients. All eligible patients will be randomized to the evolocumab group (140 mg subcutaneously injected once before revascularization + 14 days after the first dose) or the control group (no evolocumab injection). Evolocumab will then be administered depending on the patient's lipid profile. Both groups will be treated simultaneously with standardized secondary preventive medications. The primary end points are major adv...
Source: Advances in Therapy - February 27, 2021 Category: Drugs & Pharmacology Source Type: research
Statins do not cause muscle aches and pains, study finds
UK researchers seek to dispel concerns over pills prescribed for those at higher risk of heart attack and strokesStatins are generally not the cause of the muscle aches and pains that stop some people taking the pills prescribed to protect them against serious heart problems, according to a novel study that hopes to dispel some of the concerns.Two million people in the UK who are at higher risk of heart attack and strokes are eligible for statins, but many people refuse them or have stopped taking them because of sometimes alarming and widespread reports of muscle pain. But the study funded by the National Institute of Hea...
Source: Guardian Unlimited Science - February 24, 2021 Category: Science Authors: Sarah Boseley Health editor Tags: Statins Medical research Health Ageing UK news Heart attack Stroke Heart disease Science Society Source Type: news
Risk of PE significantly raised well beyond six weeks post-surgery
Postoperative pulmonary embolism risk still elevated 7-12 weeks later, regardless of the type of procedure Related items fromOnMedica Prescribe higher dose opioids for shorter time after surgery Poor pain management - a major cause of opioid crisis Statin use after stroke not linked to bleeds Don ’t delay young children’s surgery for fear of GA harms Earlier thrombolysis improves stroke outcomes
Source: OnMedica Latest News - October 9, 2019 Category: UK Health Source Type: news
How to continue lipid-lowering therapy in patients with coronary heart disease and severe liver dysfunction?: A case report of plaque regression by a combination of Chinese and Western Medicine
Rationale:
Atherosclerotic cardiovascular disease (ASCVD), including coronary heart disease (CHD), atherosclerotic stroke and peripheral vascular disease, has become the most deadly chronic noncommunicable disease throughout the world in recent decades, while plaque regression could reduce the occurrence of ASCVD. Traditional Chinese Medicine (TCM) has been widely used for prevention and treatment of these diseases. In the perspective of TCM, phlegm and blood stasis are considered to be leading pathogenesis for CHD. Hence, activating blood circulation and dissipating phlegm, which is of great benefit to regress plaque, h...
Source: Medicine - October 1, 2019 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
An attempt to explain the bidirectional association between ischaemic heart disease, stroke and depression: a cohort and meta-analytic approach.
CONCLUSIONS: The bidirectional association between CVD and depression was not explained by shared risk factors, misclassification or non-response.Declaration of interestNone.
PMID: 31179963 [PubMed - as supplied by publisher]
Source: The British Journal of Psychiatry for Mental Science - June 12, 2019 Category: Psychiatry Tags: Br J Psychiatry Source Type: research
Preventable Cases of Oral Anticoagulant-Induced Bleeding: Data From the Spontaneous Reporting System
Conclusion: Our findings describe the most reported risk factors for preventability of oral anticoagulant-induced bleedings. These factors may be useful for targeting interventions to improve pharmacovigilance activities in our regional territory and to reduce the burden of medication errors and inappropriate prescription.
Introduction
Oral anticoagulant therapy is widely used for the prevention of stroke and systemic embolism in patients with atrial fibrillation, or for the prevention and treatment of deep vein thrombosis and pulmonary embolism (Raj et al., 1994; Monaco et al., 2017). Oral anticoagulants can be di...
Source: Frontiers in Pharmacology - April 29, 2019 Category: Drugs & Pharmacology Source Type: research
Fool Me Once: An Uncommon Presentation of PE
BY FREDDIE IRIZARRY-DELGADO; VAROON KAKAIYA; & AHMED RAZIUDDIN, MDAn 86-year-old African-American woman was brought to the ED by her daughter after two days of nutritional neglect, abdominal pain, and altered mental status. Her daughter said her mother felt lightheaded, appeared dehydrated, and vomited nonbilious watery fluid once. The patient had a history of diabetes mellitus type 2, DVT/PE, dementia, and early signs of parkinsonism.Her vital signs were remarkable only for tachypnea (24 bpm). Her troponin I was markedly elevated at 1.7 ng/mL. A D-dimer was ordered because of her history of unprovoked DVT/PE, and i...
Source: The Case Files - November 27, 2018 Category: Emergency Medicine Tags: Blog Posts Source Type: research
Vascular Involvement in Axial Spondyloarthropathies
Publication date: Available online 19 May 2018Source: Joint Bone SpineAuthor(s): Clément Prati, Céline Demougeot, Xavier Guillot, Maxime Sondag, Frank Verhoeven, Daniel WendlingAbstractAnkylosing spondylitis (AS) is a chronic inflammatory joint disease that involves the entheses, causing inflammatory pain and functional impairments. Patients may experience extraarticular manifestations such as uveitis, psoriasis, and inflammatory bowel disease. These, together with the increased risk of cardiovascular disease and osteoporosis and the development of spinal fusion, are the main determinants of adverse disease outcomes. As ...
Source: Joint Bone Spine - July 10, 2018 Category: Orthopaedics Source Type: research
A Discrete Event Simulation Model to Assess the Economic Value of a Hypothetical Pharmacogenomics Test for Statin-Induced Myopathy in Patients Initiating a Statin in Secondary Cardiovascular Prevention
ConclusionWe found that a strategy favoring patients staying on statin therapy is cost effective even if patients maintained on statin are at risk of rhabdomyolysis. Our results are explained by the fact that statins are highly effective in reducing the CV risk in patients at high CV risk, and this benefit largely outweighs the risk of rhabdomyolysis.
Source: Molecular Diagnosis and Therapy - April 12, 2018 Category: Molecular Biology Source Type: research
