[The Eyes Movement Desensitization and Reprocessing for children with traumatic traumatic stress disorder: A Tunisian experience].
Authors: Bourgou S, Ben Mansour N, Bouasker A, Ridha R, Zaghrout M, Belhadj A Abstract OBJECTIVES: Evaluate the effectiveness of the Eyes Movement Desensitization and Reprocessing psychotherapy for children with Post-Traumatic Stress Disorder. METHODS: A retrospective study was conducted in the Child Psychiatry Department of CHU Mongi Slim, Marsa (Tunis, Tunisia). All Outpatients with a Post-Traumatic Stress Disorder diagnosis and who had Eyes Movement Desensitization and Reprocessing psychotherapy during the period from July 2016 to May 2018 were included. They were evaluated according to DSM 5 criteria in pre...
Source: L Encephale - September 23, 2019 Category: Psychiatry Tags: Encephale Source Type: research

The clinical and economic impact of three-monthly long-acting formulation of paliperidone palmitate versus the one-monthly formulation in the treatment of schizophrenia in France: A cost-utility study.
CONCLUSION: With slightly better QALY outcomes and a cost-saving effect when compared to PP1M, introducing PP3M is an improvement to the current treatment in France. PMID: 31542210 [PubMed - as supplied by publisher] (Source: L Encephale)
Source: L Encephale - September 23, 2019 Category: Psychiatry Tags: Encephale Source Type: research

Anxiety and performance.
Authors: Palazzolo J Abstract In the world of sport, athletes and their trainers see competitive emotions and, in particular, performance anxiety as one of the most important factors likely to influence the outcome of a sports competition. These emotions attract such vast interest because even today they continue to raise many questions. While positive emotions are generally considered to be largely facilitative to an athlete's performance, the link between negative emotions, and particularly competitive anxiety, and performance seems less unanimous. Some view anxiety as a phenomenon which hampers performance; for ...
Source: L Encephale - September 23, 2019 Category: Psychiatry Tags: Encephale Source Type: research

Schizotypal Personality Questionnaire-Brief: Effect of invalid responding on factor structure analysis and scores of schizotypy.
CONCLUSIONS: Random responding and social desirability could influence scores of schizotypy and factor structure. Simple methods could be used to identify invalid responses. The effect of social desirability could be linked to the phrasing of items. PMID: 31542212 [PubMed - as supplied by publisher] (Source: L Encephale)
Source: L Encephale - September 23, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[Use of psychotherapy among adults with a history of suicide attempt: Results form a large population-based study].
DISCUSSION: One third of adults with a lifetime suicide attempt and close to half of those with a past-year attempt have received some form of psychotherapy in the course of their life. In line with prior work, higher education and income level predicted past-year use of psychotherapy among adults with a prior suicide attempt. These findings highlight the association between major depressive disorder or anxiety disorders and increased odds of undergoing psychotherapy in the previous 12 months among adults with prior attempt. While pharmacological treatment, inpatient hospitalizations for mental health problems, visits with...
Source: L Encephale - September 23, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[Post-traumatic stress disorder in reaction to psychotic experience: A systematic revue].
CONCLUSION: A psychotic experience could be traumatic for patients and lead to complete PTSD. Although it appears as a non-consensual clinical entity, from a likely epistemological slip of the definition of "psychotrauma", the consideration of potential PTSD-PP presents an undoubted clinical relevance. Indeed, it could help practioners to precise the semiological analysis of patients recovering from an acute psychotic episode; to impact the prognosis of psychosis, thinking about impairment on the quality of life and the affective and suicidal comorbidities; and to modify the therapeutic approach in the recovery o...
Source: L Encephale - September 17, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[Malignant neuroleptic syndrome: An atypical case in an adolescent affected by bipolar I disorder associated with catatonic syndrome].
Authors: Fernandez A, Pendaries G, Dor E, Askenazy F, Thümmler S PMID: 31522832 [PubMed - as supplied by publisher] (Source: L Encephale)
Source: L Encephale - September 17, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[Midwives' feelings about the post-partum care of women with severe mental illness: A qualitative analysis].
This study is a prospective, exploratory, qualitative analysis. Twenty midwives from Grenoble Alpes University Hospital who took care of one of the selected patients participated in this study. Two women had schizophrenia and one bipolar disorder. Interviews realized with a semi-structured guide were fully transcribed, anonymized and thematically analyzed. Topics have been structured according to the number of occurrences to build a thematic tree. RESULTS: Midwives felt insecure and resourceless when the postpartum care was unclear, insufficiently anticipated and in case of a danger for the women or the children. They ...
Source: L Encephale - September 17, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[Miss V: Delusion of pregnancy during pre-menopause].
Authors: Meudal J, Sabbagh O, Lejoyeux M PMID: 31522834 [PubMed - as supplied by publisher] (Source: L Encephale)
Source: L Encephale - September 17, 2019 Category: Psychiatry Tags: Encephale Source Type: research

Quantifying efficacy of investigation during a simulated psychiatric interview.
CONCLUSION: I2/Q ratio may provide a consistent quantitative measure of a student's efficiency in assessing suicidal risk. Further research is now needed to evaluate its consistency in other clinical cases. PMID: 31522835 [PubMed - as supplied by publisher] (Source: L Encephale)
Source: L Encephale - September 17, 2019 Category: Psychiatry Tags: Encephale Source Type: research

Acceptability, attitudes and knowledge towards Transcranial Magnetic Stimulation (TMS) among psychiatrists in France.
The objective of this study was to determine the acceptability of TMS by psychiatrists and to analyze the factors influencing it. METHOD: A sample of psychiatrists was recruited in order to complete an online quantitative acceptability study using a four variable domain model (utility, intention of use, facility, risk) allowing an acceptability score calculation. RESULT: Four hundreds and seventy-six observations were included in the analysis. Regarding the main objective, the overall TMS acceptability score was high for 47.2% of psychiatrists, average for 40.6% and low for 12.1% of them. The main factors influenci...
Source: L Encephale - September 17, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[ADI-R and ADOS and the differential diagnosis of autism spectrum disorders: Interests, limits and openings].
CONCLUSIONS: The problematics of differential diagnosis remain critical for clinical approaches to autism. Therefore, formalizations of the diagnostic procedures must be able to remain open-minded and accompanied by a creative clinical approach, especially in the case of complex situations that are not soluble by means of conventional diagnostic tools. One possibility may lie in the deepening of the phenomenological approach to autism as an attempt to model the subjective phenomena of autistic subjects and thus operationalize elements that serve the diagnostic process. In the same way, a psychodynamic epistemology could he...
Source: L Encephale - September 10, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[Network analyses: Are we moving toward a new conceptualization and treatment of mental disorder?]
Authors: Bortolon C, Raffard S Abstract In a break with categorical and dimensional approaches and thus the classical medical model, the network approach applied to psychopathology constitutes a holistic approach to mental disorders. In this approach, mental disorders are conceived as an interconnected system of symptoms in which symptoms are the cause of each other. It is suggested that the interaction between the different symptoms would result in a feedback loop that leads to the installation and maintenance of these symptoms/disorders. In addition, this approach proposes that co-morbidities are the result of sy...
Source: L Encephale - September 10, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[Prevalence and characteristics of sexual dysfunction among Moroccan patients consulting for a first depressive episode].
CONCLUSIONS: The prevalence of sexual dysfunction is high in depressed patients. It significantly impacts the couple's quality of life. Although our main limitation was the small sample size which prevented us from doing a multi-varied analysis, the robust nature of this study lies in documenting the initial prevalence and types of sexual dysfunctions in both sexes in the first major depressive episode unrelated to the dysfunctions induced by antidepressant drugs. The early identification of sexual disorders and the consideration of couple dynamics would be two important elements in the management of the depressed patient....
Source: L Encephale - September 10, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[What university child psychiatry for tomorrow?]
Authors: Lachal J, Piot MA, Sibeoni J PMID: 31495552 [PubMed - as supplied by publisher] (Source: L Encephale)
Source: L Encephale - September 10, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[Impulsivity and obesity in children with Attention Deficit Hyperactivity Disorder: A clinical, neuropsychological and magnetic resonance spectroscopy exploratory study].
CONCLUSIONS: Our results are concordant with the hypothesis that impulsivity could be the link between obesity and ADHD in a population of children with ADHD. The right prefrontal regions seem to be areas of interests that need more research in the study of the link between obesity and ADHD. PMID: 31492416 [PubMed - as supplied by publisher] (Source: L Encephale)
Source: L Encephale - September 9, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[Ensuring safety of patients under antipsychotic drugs: Impact of medical and pharmaceutical collaboration at prison].
CONCLUSION: The actions of improvement collectivelly implemented in 2011 had a concrete impact on patients in the follow-up in 2015. PMID: 31443918 [PubMed - as supplied by publisher] (Source: L Encephale)
Source: L Encephale - August 26, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[Coercive stress in psychiatric intensive care unit: What link with insight?]
Authors: Lamothe H, Lebain P, Morello R, Brazo P Abstract The aim of this work was to study the correlations between the coercive experience level in patients in a psychiatric intensive care unit and clinical insight. We included 40 patients without specific diagnosis criteria at the end of their hospitalization in the intensive care unit. We assessed patients with the Coercion Experience Scale (CES) to measure their coercive stress level, and the Scale to Assess Unawareness of Mental Disorder (SUMD) which measures clinical insight. A total of 42.5 % of our sample suffered from mood disorders, 50 % suffer...
Source: L Encephale - August 21, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[Factors associated with Internet addiction among Tunisian adolescents].
Authors: Ben Thabet J, Ellouze AS, Ghorbel N, Maalej M, Yaich S, Omri S, Feki R, Zouari N, Zouari L, Dammak J, Charfi N, Maalej M Abstract INTRODUCTION: Internet addiction, a relatively new phenomenon, is a field of recent research in mental health, particularly within young populations. It seems to interact with several individual and environmental factors. OBJECTIVES: We aim to spot internet addiction in a Tunisian adolescent population, and to study its relationship with personal and family factors, as well as with anxious and depressive comorbidities. METHODS: We conducted a cross-sectional study of 253...
Source: L Encephale - August 21, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[One homeless person out of ten suffers from cognitive disorders: What do we know about these impairments? A systematic review of homeless people's cognition].
CONCLUSIONS: We confirm that homeless people often suffer from cognitive difficulties, and some of these difficulties (memory, executive functioning) are severe. Yet the etiology of these disorders remain relatively unknown: even if we observe a high prevalence of psychiatric, substance-related, neurodevelopmental and neurological issues by the homeless population, only a few of them (brain injury history and childhood trauma) seem to be correlated with cognition in homelessness. The potential explicative factors have been too rarely explored to bring a powerful explanation of cognitive disorders in homeless people. Furthe...
Source: L Encephale - August 21, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[Characteristics of patients who received an indication of involuntary admission, with or without the involvement of a third party, in a Parisian psychiatric emergency unit].
CONCLUSION: Our exploratory results help to better understand how the ASPPI procedure is used in psychiatric emergency wards six years after enactment of the law. They highlight the differences between ASPPI patients and ASPDT/u and raise ethical issues regarding involuntary psychiatric care. PMID: 31421813 [PubMed - as supplied by publisher] (Source: L Encephale)
Source: L Encephale - August 21, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[Can ADHD have an adulthood onset?]
Authors: Ilario C, Alt A, Bader M, Sentissi O Abstract ADHD is the most common psychiatric disorder of childhood. It is considered to be a neurodevelopmental disorder that may persist from chilhood into adulthood. In childood it is associated with several outcomes such as inattention, hyperactivity and impulsivity. Symptoms may change as a person gets older with an increased risk of developing psychiatric comorbidities such as depression, anxiety and substance addiction. However, recent studies diverge from the traditional perspective. These authors hypothesized that ADHD may appear in adulthood, not as a continuat...
Source: L Encephale - July 2, 2019 Category: Psychiatry Tags: Encephale Source Type: research

The use of melatonin in adult psychiatric disorders: Expert recommendations by the French institute of medical research on sleep (SFRMS).
Authors: Geoffroy PA, Micoulaud Franchi JA, Lopez R, Schroder CM, membres du consensus Mélatonine SFRMS Abstract Melatonin is a hormone secreted by the pineal gland at night. This hormone has many physiological functions, the main one being to synchronise individuals' biological rhythms. Exogenous melatonin has the same chronobiotic action, even at small doses (0.125mg). In addition, a sleep-inducing (soporific) action appears to occur in a dose-effect relationship, i.e. as the dose increases. In psychiatric disorders, these two effects could have interesting applications in clinical practice. The French ins...
Source: L Encephale - July 1, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[Effects of Dacryodes edulis fruit oil on anxiety symptoms and cognitive performance in mice, after prolonged administration].
CONCLUSION: The results confirm anxiolytic effects and improved cognitive performance after prolonged oral administration of HDE in rodents. PMID: 31229243 [PubMed - as supplied by publisher] (Source: L Encephale)
Source: L Encephale - June 25, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[Psychiatry resident confronted to the suicide of a patient: A common situation in France].
Authors: Allali R, Reyre A, Baubet T PMID: 31230759 [PubMed - as supplied by publisher] (Source: L Encephale)
Source: L Encephale - June 25, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[From psychiatry and neurology to neuropsychiatry: Back to the future?]
Authors: Magne H PMID: 31227208 [PubMed - as supplied by publisher] (Source: L Encephale)
Source: L Encephale - June 24, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[Catatonia education in France: A cross-sectional study].
CONCLUSION: Specific education seems to improve the knowledge of young doctors and their ability to diagnose and treat catatonic patients. This education remains poorly provided and heterogeneous on the French territory. Catatonia deserves a place in the teaching program of the psychiatry DES, thus to become systematic. PMID: 31227209 [PubMed - as supplied by publisher] (Source: L Encephale)
Source: L Encephale - June 24, 2019 Category: Psychiatry Tags: Encephale Source Type: research

Assessing metacognition during or after basic-level and high-level cognitive tasks? A comparative study in a non-clinical sample.
This study explored in a non-clinical sample whether metacognitive awareness assessments measured during ("on line") and after ("end line") a neuropsychological task lead to comparable results in tests exploring basic-level or high-level cognitive functions. Short-term memory and working memory tests (forward and backward digit recall of the WAIS-III) were used to measure basic-level cognitive function. A social cognition test, the French adaptation of the Faces Test, was used to assess high-level cognitive function through recognition of facial emotions. For these two tests, we explored "on line&q...
Source: L Encephale - June 24, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[The global cardiovascular risk of patients with schizophrenia hospitalized in psychiatry at the university hospital of Saint- Étienne].
CONCLUSION: Using the global cardiovascular risk approach as a primary prevention measure could allow patients suffering from schizophrenia to be admitted earlier. Also, regularly reevaluating that risk could allow initiation of behavioral changes and/or important cardiovascular treatments. PMID: 31178036 [PubMed - in process] (Source: L Encephale)
Source: L Encephale - June 11, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[Mental health of children in foster care, a literature review].
Authors: Even M, Sutter-Dallay AL Abstract In France more than 140 000 children live in foster homes under the responsibility of the French Child Protection Agency. These children have lived in environments that cannot be good for their development and have been separated from their families which have to have consequences on their mental development. A literature review in France and abroad was made to identify the profiles of these children, their risk factors, and the mental disorders they can present. French child protection is handled by smaller territories, called Départements of which there ...
Source: L Encephale - June 10, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[Stopping and reducing smoking in patients with schizophrenia].
CONCLUSION: Smoking cessation strategies for patients with schizophrenia appear to be effective and should combine (1) smoking cessation medications with sufficient duration, (2) diversified psychosocial approaches and (3) physical activity practice. PMID: 31153585 [PubMed - as supplied by publisher] (Source: L Encephale)
Source: L Encephale - June 5, 2019 Category: Psychiatry Tags: Encephale Source Type: research

Interventional neuropsychology and beyond: The expanding role of therapeutic brain stimulation in psychiatry.
Authors: De Wandel L, Brem AK, Hoy K PMID: 31155140 [PubMed - as supplied by publisher] (Source: L Encephale)
Source: L Encephale - June 5, 2019 Category: Psychiatry Tags: Encephale Source Type: research

Risk factors for return visits and rehospitalizations to the child emergency psychiatric unit: A retrospective study over 2 years at Saint- Étienne University Hospital.
CONCLUSION: Knowledge of risk factors would allow implementation of secondary or tertiary preventive devices. Students could undergo early screening of psychiatric pathologies using mobile screening teams which would save money, avoid hospitalizations, and when necessary, facilitate both hospitalization and return visits. PMID: 31113536 [PubMed - as supplied by publisher] (Source: L Encephale)
Source: L Encephale - May 23, 2019 Category: Psychiatry Tags: Encephale Source Type: research

3rd European Conference on brain stimulation in psychiatry  - From mechanism to medicine.
3rd European Conference on brain stimulation in psychiatry - From mechanism to medicine. Encephale. 2019 May 16;: Authors: Brunelin J, Mondino M, Arns M, Baeken C, Brem AK, Filipčić I, Ganho-Avila A, Palm U, Poleszczyk A, Sauvaget A, O'Shea J, D'Urso G, Poulet E PMID: 31104764 [PubMed - as supplied by publisher] (Source: L Encephale)
Source: L Encephale - May 22, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[Is still psychiatry interested by patient's souls?]
Authors: Salles J, Sporer M, Schmitt L PMID: 31109653 [PubMed - as supplied by publisher] (Source: L Encephale)
Source: L Encephale - May 22, 2019 Category: Psychiatry Tags: Encephale Source Type: research

Promoting psychiatrist-pediatrician collaborations on postnatal depression prevention.
Authors: Brunais E, Leroy A, Touchard A, Pelta J, Tanguy A, GRoup of REsearch of North PAediatricians, Guedeney A, Delion P, Jardri R, Medjkane F PMID: 31109654 [PubMed - as supplied by publisher] (Source: L Encephale)
Source: L Encephale - May 22, 2019 Category: Psychiatry Tags: Encephale Source Type: research

rTMS for treatment of negative symptoms in schizophrenia: Clinical effects and neural basis.
Authors: Lavallé L, Aleman A PMID: 31101378 [PubMed - as supplied by publisher] (Source: L Encephale)
Source: L Encephale - May 19, 2019 Category: Psychiatry Tags: Encephale Source Type: research

The frontier of tDCS in psychiatry and the role of new technologies.
Authors: Simon L, Bikson M PMID: 31088687 [PubMed - as supplied by publisher] (Source: L Encephale)
Source: L Encephale - May 16, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[The concept of narrative insight in schizophrenia: A systematic review].
CONCLUSION: It seems necessary to take into account the concept of narrative insight in order to evaluate insight of patients suffering from mental illness. This implies that the evaluation methods of insight as well as the clinical practice must evolve to adapt to the culture and subculture of the patient. This could have beneficial effects on the well-being of patients, therapeutic relations, access to treatment as well as psychiatric research, as well as limit controversies around this topic. It would be interesting to confirm this new conception of insight and the therapeutic relations by carrying out new studies as we...
Source: L Encephale - April 29, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[Emotional therapies for overweight or obesity].
Authors: Julien Sweerts S, Apfeldorfer G, Kureta-Vanoli K, Romo L Abstract Obesity has become a public health problem. But care, mainly diets, is often ineffective over the long term. Emotional therapies seem to be an interesting track especially for emotional eating. After defining two key concepts of emotional eating and acceptance, the theoretical frameworks of the different emotional therapies used in the treatment of overweight or obesity will be presented: Mindfulness-Based for Eating Disorder (MB-EAT), Acceptance and Commitment Therapy, and Acceptance-Based Behavioral Treatment for Weight Loss (ABT). The goa...
Source: L Encephale - April 11, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[Mental health educational programs in schools: Experiences, needs and expectations expressed by students in France].
CONCLUSION: This exploratory study highlights the lack of mental health educational programs in schools and the need expressed by students themselves. It suggests directions to think about how to develop these mental health preventive programs, evoking their limits and advantages. PMID: 30961970 [PubMed - as supplied by publisher] (Source: L Encephale)
Source: L Encephale - April 11, 2019 Category: Psychiatry Tags: Encephale Source Type: research

The aftermath of resilience in the global world.
Authors: Derivois D Abstract Just as there is an aftermath of trauma, there is reason to think of an aftermath of resilience, different from the resilience capacities developed after a trauma. The aftermath of resilience reflects the ability to activate resilient memory in response to traumatic memory in order to rebuild oneself. This is a major challenge for the global mental health of our fragile societies. The challenge is significant for France, Europe and the world. Beyond the overuse of the word resilience in scientific literature and the media, it contributes to the methodology, epistemology and politics of ...
Source: L Encephale - April 11, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[Evaluation of injunction to care practices: A study of 119 cases].
CONCLUSIONS: Most of the subjects in injunction to care had no axis I disorder but addictions and/or pathological personality traits. Nevertheless, the expert concluded the need of an IC. Personality and behavior disorders do not always require psychiatric care, and the management must be multidisciplinary. In France, the psychiatrist remains at the center of injunction to care measure. The addictology care is not developed whereas it is a population at risk and there is a lack of interactions between professionals (medical, social and judicial professionals). The IC is a measure that needs to be improved by means of bette...
Source: L Encephale - April 11, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[The schizophrenic's chilhood].
Authors: Fourneret P, Da Fonseca D Abstract Pathology of adolescence and young adult, schizophrenia can begin in very rare cases during childhood. Two early clinical forms of the disorder have been identified by epidemiological studies: one beginning at the age of 15; the other around 9 years old; While many questions remain unsanswered about the neurobiological and environmental factors - common or distinct - of these two clinical phenotype, both are related to a profoun and lasting alteration of the neurocognitive development whose origin would clearly go back to infancy or to the antenal period. Here we will pre...
Source: L Encephale - April 4, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[Specific treatment of the first psychotic episodes].
Authors: Krebs MO, Lejuste F, Martinez G Abstract Early detection and early intervention programs in early adolescent and young adult psychosis have developed in many countries and have shown their effectiveness. The main lesson of these programs is to have demonstrated that the progression of at-risk mental state into to a full-blown psychosis or of a psychotic episode to a chronic schizophrenic disorder is evitable. They have also shown that the earlier appropriate care is set up the better the functional remission and that the period of "early psychosis" encompassing the period preceding the emergence ...
Source: L Encephale - April 4, 2019 Category: Psychiatry Tags: Encephale Source Type: research

Can schizophrenia be predicted on the basis of a symptom? A psychopathological appraisal of early detection research in schizophrenia.
Authors: Parnas J, Zandersen M Abstract Predictive prospective studies of schizophrenia date back to the late 1950s. At the turn of the Millennium, an Australian research group initiated programs of early detection of schizophrenia and early therapeutic intervention. The theoretical foundations of early schizophrenia detection usually remain unaddressed. In this paper, we focus on the issue of prediction of future schizophrenia in the general population on the basis of a symptomatic picture. Several notions used in this research program such as disease, symptom, and clinical staging derive from a medical model, whi...
Source: L Encephale - April 4, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[Has the concept of staging modified treatment of schizophrenia yet ?]
Authors: Conus P Abstract The concept of staging is applied in medicine since many years, in order to better adapt treatment to patients' needs. Some authors have suggested one should also apply this concept to psychiatric disorders. If this approach seems to make sense, concrete progress in the domain are still limited. It is in the field of psychosis that most development have occurred, in the favorable context of early intervention programs. Some very detailed models have recently been proposed where successive stages of psychotic disorders are defined and corresponding treatment options are proposed. However, t...
Source: L Encephale - April 4, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[The staging model (or evolutionary stages) applied to bipolar disorder].
Authors: Scott J, Henry C Abstract In psychiatry, clinical staging raises awareness of the need to understand disease trajectories and heterotypic continuity; it draws attention to individuals at risk of developing disorders, such as those with a family history or subsyndromal presentations; and it actively promotes greater attention to prevention strategies and interventions for individuals at ultra-high risk of developing a severe mental disorder. Staging paradigms have been increasingly applied in early intervention in psychoses, but there are issues in broadening the scope of clinical staging to the more preval...
Source: L Encephale - April 4, 2019 Category: Psychiatry Tags: Encephale Source Type: research

Quantitative System Pharmacology (QSP): An Integrative Framework for paradigm change in the treatment of the first-episode schizophrenia.
Authors: Gaillard-Bigot F, Zendjidjian XY, Kheloufi F, Casse-Perrot C, Guilhaumou R, Micallef J, Fakra E, Azorin JM, Blin O Abstract Despite the lack of progress in the curative treatment of mental illness, especially schizophrenia, the accumulation of neuroscience data over the past decade suggests the re-conceptualization of schizophrenia. With the advent of new biomarkers and cognitive tools, new neuroscience technologies such as functional dynamic connectivity and the identification of subtle clinical features; it is now possible to detect early stages at risk or prodromes of a first psychotic episode. Current ...
Source: L Encephale - April 4, 2019 Category: Psychiatry Tags: Encephale Source Type: research

[Suicidal risk during the first psychotic episode].
Authors: Courtet P Abstract Suicide is the most common cause of early mortality during the course of schizophrenia. The most recent data in the literature show that the risk of suicide is greater at the beginning of the course of schizophrenia. The risk of suicide during the first year is 12 times higher than that of the general population. Specifically, 2-5 % of people with first-episode psychosis will die by suicide in long-term follow-up studies. Regarding the presence of suicidal ideation that are a major factor of suicide in subjects suffering from psychotic disorders, their prevalence remains extremely worryi...
Source: L Encephale - April 4, 2019 Category: Psychiatry Tags: Encephale Source Type: research