An attempt to explain the bidirectional association between ischaemic heart disease, stroke and depression: a cohort and meta-analytic approach.

CONCLUSIONS: The bidirectional association between CVD and depression was not explained by shared risk factors, misclassification or non-response.Declaration of interestNone. PMID: 31179963 [PubMed - as supplied by publisher]
Source: The British Journal of Psychiatry for Mental Science - Category: Psychiatry Tags: Br J Psychiatry Source Type: research

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Publication date: Available online 22 October 2019Source: Sensors and Actuators A: PhysicalAuthor(s): Dong Sun, Yu-juan Tang, Jiong Wang, Xin-jie WangAbstractIn this contribution, an H-shaped piezoelectric motor based safety and arming device that is driven by the hybrid of symmetrical first longitudinal mode and second bending mode is proposed, designed and experimental investigated. The proposed system operates based on the concept of self-moving and show potential infield of fuse system with different calibers. The actuating mechanism is that the four driving feet contact with the guides alternately and push the motor t...
Source: Sensors and Actuators A: Physical - Category: Physics Source Type: research
Publication date: Available online 23 October 2019Source: Life SciencesAuthor(s): Qi Li, Xinglan An, Xiaxia Man, Meiran Chu, Tianchuang Zhao, Hao Yu, Ziyi LiAbstractAimsThe present study aimed to investigate the effects of cyclophosphamide (Cytoxan, CTX) on premature ovarian failure (POF) in mice and its regulatory mechanisms by transcriptome analysis.Main methodsFemale C57BL/6 mice were treated with a single intraperitoneal injection of 70 mg/kg CTX. Serum levels of estradiol (E2) and follicle stimulating hormone (FSH) were measured by enzyme-linked immunosorbent assay (ELISA), and follicular structure differences were ob...
Source: Life Sciences - Category: Biology Source Type: research
Publication date: Available online 22 October 2019Source: Life SciencesAuthor(s): Pollyana S. Siqueira-Lima, Jullyana S.S. Quintans, Luana Heimfarth, Fabiolla R.S. Passos, Erik W.M. Pereira, Marilia M. Rezende, José E.R. Menezes-Filho, Rosana S.S. Barreto, Henrique D.M. Coutinho, Adriano A.S. Araújo, Aline S. Medrado, Ligia A. Naves, Horácio F. Bomfim, Angélica M. Lucchese, Sathiyabama Rajiv Gandhi, Lucindo J. Quintans-JúniorAbstractNeuropathic pain (NP) is a difficult condition to treat because of the modest efficacy of available drugs. New treatments are required. In the study we aimed ...
Source: Life Sciences - Category: Biology Source Type: research
Publication date: Available online 22 October 2019Source: Life SciencesAuthor(s): Chao He, Guiting Zhang, Hang Ouyang, Peng Zhang, Yudan Chen, Ren Wang, Hong ZhouAbstractAimsβ2-glycoprotein I/anti-β2-glycoprotein I antibody complex (β2/aβ2) could promote oxLDL-induced endothelial inflammation through Toll-like receptor 4 (TLR4), therefore accelerates atherosclerosis in patients with anti-phospholipid syndrome (APS). However, effects of β2/aβ2 and TLR4 on oxLDL-induced CD36 activation in macrophages remain to be elucidated and are currently under investigation.Materials and MethodsTHP-1 macroph...
Source: Life Sciences - Category: Biology Source Type: research
Authors: Lyu J, Xie Y, Wang Z, Wang L Abstract BACKGROUND This meta-analysis was conducted to evaluate the clinical effectiveness and safety of Salvianolic acids for injection (SAFI) plus conventional treatment (CT) for patients with acute cerebral infarction (ACI) and to assess the evidence to guide clinical practice. MATERIAL AND METHODS PubMed, EMBASE, Cochrane Library, Web of Science, and 4 Chinese electronic databases were searched to identify relevant randomized controlled trials (RCTs). The methodological quality of eligible studies was evaluated using the Cochrane risk of bias tool. The reporting quality of...
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
A Triangle contact research organization has netted a massive federal contract, positioning the company to receive a steady stream of revenue for several years. Durham-based Duke Clinical Research Institute will receive $90 million in funding from the National Institute of Aging and the National Heart, Lung,&Blood – both subsets of the National Institutes of Health (NIH). The award will fund the first study into the effectiveness of statins –  a class of lipid-lowering medications prescribed…
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
Publication date: Available online 22 October 2019Source: Preventive MedicineAuthor(s): Mette Stavnsbo, Eivind Aadland, Sigmund A. Anderssen, Mai Chinapaw, Jostein Steene-Johannessen, Lars B. Andersen, Geir K. ResalandAbstractThe onset of cardiometabolic diseases are recognized to occur in childhood. We aimed to investigate the effect of a school-based cluster-randomized controlled trial of physical activity (PA) on single and clustered cardiometabolic risk factors.We included 1129 fifth-grade children from 57 schools (≥seven children in each class) in Sogn and Fjordane County, Norway. The PA intervention was conducted ...
Source: Preventive Medicine - Category: International Medicine & Public Health Source Type: research
ConclusionBased on our experience and the literature, we successfully discuss bowel perforation management with respect to the ventriculoperitoneal shunt, including the utility of the ventriculoatrial shunt as an alternative.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
Rogan, S, Haehni, M, Luijckx, E, Dealer, J, Reuteler, S, and Taeymans, J. Effects of hip abductor muscles exercises on pain and function in patients with patellofemoral pain: A systematic review and meta-analysis. J Strength Cond Res 33(11): 3174–3187, 2019—This systematic review and meta-analysis considered the effects of hip strengthening (i.e., abductor and external rotator muscles) vs. no hip strengthening on pain and of hip strengthening combined with knee strengthening vs. knee strengthening (i.e., quadriceps muscles) alone on pain and functional status in patients with patellofemoral pain (PFP). Eleven, ...
Source: Journal of Strength and Conditioning Research - Category: Sports Medicine Tags: Original Research Source Type: research
Friends i applied to 350 IM programs still no interviews. Credentials .step1 221,step2 ck 227 (cs fail history is there). ECFMG certified.Step 3 213..Did phd in diabetes,yog 2010. US IMG .How can i improve my chances.Really depressed these days.Spend a lot of money on this journey. I need help
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Medical Students - MD Source Type: forums
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