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Single-patient trials helpful in determining statin tolerability
Single-patient, or n-of-1, trials may be a useful method for determining which patients are experiencing true statin-related discomfort and which patients may be able to continue therapy, according to an article being published in Annals of Internal Medicine.Statins are recommended to reduce risk for heart disease, stroke, and other cardiovascular problems. Myalgia (muscle pain or discomfort) is a common complaint among patients taking statins and a common reason for discontinuation of therapy. However, it can be difficult to determine whether statins are the cause of patient discomfort.
Source: Health News from Medical News Today - March 5, 2014 Category: Consumer Health News Tags: Statins Source Type: news

Thalamic cramplike pain
Conclusions and relevance: Thalamic cramplike pain should be recognized as a type of central post-stroke pain, probably produced by lesions localized to the border between the ventral posterior and pulvinar nuclei and connected to the ipsilateral primary somatosensory cortex and primary and secondary motor cortices.
Source: Journal of the Neurological Sciences - November 7, 2013 Category: Neurology Authors: Luciano A. Sposato, Harish A. Sharma, Ali R. Khan, Robert Bartha, Vladimir Hachinski Tags: Short Communications Source Type: research

Should I take statins?
Since 80% of cardiovascular disease is caused by lack of exercise, poor diet and smoking, it would be better to address these factors rather than pop a statinShould everyone over 50 be taking statins? asked an editorial in the Lancet last year. No, said an analysis article in last week's BMJ. Statins, in case you've escaped the hype, are drugs that block an enzyme in the liver that's needed to make cholesterol (we make it as well as eat it). Statins reduce levels of low density lipoproteins – the bad cholesterol that furs up arteries and can cause heart disease. But is there any benefit in taking a statin if yo...
Source: Guardian Unlimited Science - October 27, 2013 Category: Science Authors: Luisa Dillner Tags: The Guardian Medical research Health & wellbeing Human biology Drugs Features Life and style Science Source Type: news

Saturated fat link with heart disease questioned
This article is one doctor's opinion based on his own knowledge, research and experience. However, it is fair to say there is an ongoing debate about how far cholesterol is a risk factor for heart disease, especially in people who are otherwise healthy. There is also a similar debate about the use of statins in people who have no evidence of cardiovascular disease. This is alongside ongoing research into the components of LDL and the different types of lipoproteins known to increase risk the most. None of this relevant new evidence is covered by the news reporting.   What should you eat? There is no need to change curren...
Source: NHS News Feed - October 23, 2013 Category: Consumer Health News Tags: Heart/lungs Food/diet QA articles Source Type: news

Statin use linked to small increase in cataracts risk
Conclusion This research using a large cohort of people from a military healthcare system finds that overall, use of statins for over 90 days was associated with a slight increase in a person’s risk of developing cataracts. Further analyses suggested that the risk was higher among people who did not have any additional diseases. From this the researchers suggest that risk may be higher when statins are given for what is called primary prevention, i.e. given to people with risk factors for cardiovascular disease but who have not yet suffered any cardiovascular disease events such as a heart attack or stroke. The study h...
Source: NHS News Feed - September 20, 2013 Category: Consumer Health News Tags: Medication Older people Heart/lungs Source Type: news

Claim that statins damage muscles 'overblown'
In this study, statin users were matched with non-users so their baseline characteristics were similar. A cohort study is the ideal study design to address this question. However, despite the fact that the researchers tried to ensure there were as few differences as possible between statin users and statin non-users at baseline, it is possible that other factors (confounders) are responsible for the associations seen. A randomised controlled trial would be required to show a cause and effect relationship. Links To The Headlines Statins could lead to muscular injuries, scientists warn. The Daily Telegraph, June 4 2013 Sta...
Source: NHS News Feed - June 4, 2013 Category: Consumer Health News Tags: Medication Older people Source Type: news

Aspirin Linked To Blinding Eye Disease
WebMD Medical News By Brenda Goodman, MA Reviewed by Laura J. Martin, MD Jan. 22, 2013 — Regular aspirin users are more likely to develop the “wet” form of age-related macular degeneration compared to people who rarely or never take the drug, a new study shows. Aspirin is one of the most widely used drugs in the world. Millions of people with heart disease take a daily low dose of aspirin in hopes of preventing heart attacks and stroke. It’s also used to ease pain. Macular degeneration is a leading cause of blindness in older adults, and it is on the rise. The “wet” form accounts for on...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - January 23, 2013 Category: Consumer Health News Authors: mreal197 Tags: WebMD News Source Type: news

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