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Condition: Inflammatory Bowel Disease
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Total 222 results found since Jan 2013.
The Terrifying Way Not Sleeping Enough Actually Changes Your Gut
Studies link insufficient sleep to some pretty scary consequences, including an increased risk of stroke, heart disease, diabetes, obesity and even some cancers.
Experts still don’t fully understand why not getting enough sleep is connected to all of these conditions, but new research published this month adds one piece to the puzzle: Not getting enough sleep may cause changes to gut bacteria that could fundamentally change our metabolism, affecting a host of bodily systems.
Gut microbiota are the trillions of microorganisms living in our intestines that help keep our metabolism, immune system and othe...
Source: Science - The Huffington Post - December 23, 2016 Category: Science Source Type: news
An unusual presentation of Listeria monocytogenes rhombencephalitis
We describe a case of 52-year-old woman with a medical history of Crohn's disease presented abrupt fever, asymmetrical multiple cranial nerve palsies and focal neurological symptoms localized to the brainstem. The patient was initially diagnosed with ischaemic stroke, because of acute clinical course and results of neuroimaging. Cerebrospinal fluid analysis revealed mild infection with negative Gram staining and culture. Final diagnosis of Listeria monocytogenes brainstem infection (rhombencephalitis) was set up on the basis of further clinical course and positive blood cultures. Listerial rhombencephalitis should be kept ...
Source: Polish Journal of Neurology and Neurosurgery - January 10, 2017 Category: Neurosurgery Source Type: research
An unusual presentation of Listeria monocytogenes rhombencephalitis.
We describe a case of 52-year-old woman with a medical history of Crohn's disease presented abrupt fever, asymmetrical multiple cranial nerve palsies and focal neurological symptoms localized to the brainstem. The patient was initially diagnosed with ischaemic stroke, because of acute clinical course and results of neuroimaging. Cerebrospinal fluid analysis revealed mild infection with negative Gram staining and culture. Final diagnosis of Listeria monocytogenes brainstem infection (rhombencephalitis) was set up on the basis of further clinical course and positive blood cultures. Listerial rhombencephalitis should be kept ...
Source: Neurologia i Neurochirurgia Polska - January 9, 2017 Category: Neurology Authors: Acewicz A, Witkowski G, Rola R, Ryglewicz D, Sienkiewicz-Jarosz H Tags: Neurol Neurochir Pol Source Type: research
Crohn ' s, Colitis Increase Risk for Acute Arterial Events Crohn ' s, Colitis Increase Risk for Acute Arterial Events
Ischemic events and stroke are significantly more frequent in patients with inflammatory bowel disease than in the general population, according to a large French study.Medscape Medical News
Source: Medscape Medical News Headlines - February 17, 2017 Category: Consumer Health News Tags: Gastroenterology News Source Type: news
Clinical Reasoning: Acute onset facial droop in a 36-year-old pregnant woman
A 36-year-old woman, G1P0, 22 weeks pregnant, presented to the emergency department for evaluation of acute onset facial droop. Her medical history included ulcerative colitis, primary sclerosing cholangitis, and heterozygosity for the prothrombin G20210A mutation. She was on 10,000 units of subcutaneous heparin twice daily for a previous deep vein thrombosis secondary to her prothrombin mutation; she was noncompliant with prescribed aspirin.
Source: Neurology - June 12, 2017 Category: Neurology Authors: George, I. C., Youn, T. S., Marcolini, E. G., Greer, D. M. Tags: Other cerebrovascular disease/ Stroke, Autoimmune diseases, Critical care, All Demyelinating disease (CNS) RESIDENT AND FELLOW SECTION Source Type: research
High-fat diet leads to same intestinal inflammation as a virus
FINDINGSA new study by scientists at UCLA found that when mice eat a high-fat diet, the cells in their small intestines respond the same way they do to a viral infection, turning up production of certain immune molecules and causing inflammation throughout the body. The scientists also found that feeding the mice tomatoes containing a protein similar to that in HDL, or “good cholesterol,” along with the generic cholesterol drug Ezetimibe, reversed the inflammation.The results could lead to new types of drugs, targeting the intestinal cells, to reduce people ’s risk of heart attacks and strokes, or to treat other cond...
Source: UCLA Newsroom: Health Sciences - June 21, 2017 Category: Universities & Medical Training Source Type: news
Cardiovascular disease in immune-mediated inflammatory diseases: A cross-sectional analysis of 6 cohorts
Abstract: To analyze in several immune-mediated inflammatory diseases (IMIDs) the influence of demographic and clinical-related variables on the prevalence of cardiovascular disease (CVD), and compare their standardized prevalences.
Cross-sectional study, including consecutive patients diagnosed with rheumatoid arthritis, psoriatic arthritis, psoriasis, systemic lupus erythematosus, Crohn disease, or ulcerative colitis, from rheumatology, gastroenterology, and dermatology tertiary care outpatient clinics located throughout Spain, between 2007 and 2010. Our main outcome was defined as previous diagnosis of angina, myocardi...
Source: Medicine - June 1, 2017 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
Assessment of stability of CD34+ cell products enriched by immunoselection from peripheral blood mononuclear cells during refrigerated storage
Haematopoietic stem cell transplantation is generally used for haematopoietic regeneration after myeloablative therapy [1]. Therapeutic effects of stem cells in other diseases like heart failure [2,3], bone healing [4], chronic spinal cord injuries [5], retinal disorders [6], stroke [7], refractory Crohn disease [8] and multiple sclerosis [9] are being investigated in various clinical studies. Haematopoietic stem cells are most often collected in a mononuclear cell fraction by leukapheresis from peripheral blood.
Source: Transfusion and Apheresis Science - July 21, 2017 Category: Hematology Authors: Metka Krasna, Elvira Malicev, Jasmina Ziva Rozman, Bojan Vrtovec Source Type: research
Two Liters a Day Keep the Doctor Away? Considerations on the Pathophysiology of Suboptimal Fluid Intake in the Common Population
Suboptimal fluid intake may require enhanced release of antidiuretic hormone (ADH) or vasopressin for the maintenance of adequate hydration. Enhanced copeptin levels (reflecting enhanced vasopressin levels) in 25% of the common population are associated with enhanced risk of metabolic syndrome with abdominal obesity, type 2 diabetes, hypertension, coronary artery disease, heart failure, vascular dementia, cognitive impairment, microalbuminuria, chronic kidney disease, inflammatory bowel disease, cancer, and premature mortality. Vasopressin stimulates the release of glucocorticoids which in turn up-regulate the serum- and g...
Source: Kidney and Blood Pressure Research - August 8, 2017 Category: Urology & Nephrology Source Type: research
Abstract P334: Persistent Adrenomedullin Derivative Inhibits Development of Hypertension Session Title: Salt and Hypertension
Human adrenomedullin (hAM) consists of a 52 amino acid peptide that is amidated and has a disulfide bond. The bioactive peptide hAM has a variety of physiological functions, such as vasodilatation, hormone secretion, neurotransmission, embryogenesis, wound healing and immunoregulation. hAM has shown several therapeutic effects in experimental models of various diseases, including ischemic heart disease, inflammatory bowel disease, stroke and retinochoroidal disease. However, these therapies required continuous administration of hAM as the half-life of native hAM is quite short in blood. To resolve these issues, the aim of ...
Source: Hypertension - September 14, 2017 Category: Cardiology Authors: Sayaka Nagata, Motoo Yamasaki, Kazuo Kitamura Tags: Poster Abstract Presentations Source Type: research
Vitamin B12 Deficiency: Recognition and Management.
Abstract
Vitamin B12 deficiency is a common cause of megaloblastic anemia, various neuropsychiatric symptoms, and other clinical manifestations. Screening average-risk adults for vitamin B12 deficiency is not recommended. Screening may be warranted in patients with one or more risk factors, such as gastric or small intestine resections, inflammatory bowel disease, use of metformin for more than four months, use of proton pump inhibitors or histamine H2 blockers for more than 12 months, vegans or strict vegetarians, and adults older than 75 years. Initial laboratory assessment should include a complete blood count ...
Source: American Family Physician - September 15, 2017 Category: Primary Care Authors: Langan RC, Goodbred AJ Tags: Am Fam Physician Source Type: research
Investigating the candidacy of the serotype specific rhamnan polysaccharide based glycoconjugates to prevent disease caused by the dental pathogen Streptococcus mutans
AbstractDental caries remains a major health issue and the Gram-positive bacteriumStreptococcus mutans is considered as the major pathogen causing caries. More recently,S. mutans has been recognised as a cause of endocarditis, ulcerative colitis and fatty acid liver disease along with the likelihood of increased cerebral hemorrhage following a stroke ifS. mutans is present systemically. We initiated this study to examine the vaccine candidacy of the serotype specific polysaccharides elaborated byS. mutans. We have confirmed the carbohydrate structures for the serotype specific rhamnan containing polysaccharides from seroty...
Source: Glycoconjugate Journal - October 2, 2017 Category: Biochemistry Source Type: research
UCLA helps many to live long and prosper
In Westwood, more than 100 faculty experts from 25 departments have embarked on anall-encompassing push to cut the health and economic impacts of depression in half by the year 2050. The mammoth undertaking will rely on platforms developed by the new Institute for Precision Health, which will harness the power of big data and genomics to move toward individually tailored treatments and health-promotion strategies.On the same 419 acres of land, researchers across the spectrum, from the laboratory bench to the patient bedside, are ushering in a potentially game-changing approach to turning the body ’s immune defenses again...
Source: UCLA Newsroom: Health Sciences - November 9, 2017 Category: Universities & Medical Training Source Type: news
Can Fish Oil Help Reading?
Discussion
Fats and fatty acids are essential for good human health.
Saturated fats have hydrogen pairs linked to each carbon on the carbon backbone. They are solid or semi-solid at room temperature. Common examples are butter, lard, or hardened vegetable shortening. They are linked to higher cholesterol and triglycerides and only a small amount of them are recommended to be consumed in the diet.
Unsaturated fats have one or more hydrogen atoms missing from the carbon backbone. They are liquid at room temperature.
Monounsaturated fatty acids have one hydrogen pair that is missing from the carbon backbone. They are liq...
Source: PediatricEducation.org - November 20, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
IJERPH, Vol. 15, Pages 513: Association between Inflammatory Bowel Disease and Cholelithiasis: A Nationwide Population-Based Cohort Study
g Kao
We assessed the subsequent risk of cholelithiasis development in patients with inflammatory bowel diseases (IBDs) such as Crohn’s disease (CD) or ulcerative colitis (UC). We identified 8186 patients who aged ≥20 years and were diagnosed with IBD between 2000 and 2010 as the study cohort. A total of 8186 patients without IBD were selected by frequency-matching according to age, sex, comorbidities, and the index date of diagnosis, and they were identified as the control cohort. To measure the incidence of cholelithiasis, all patients were followed up until the end of 2011. The risk of developing cholelithiasis,...
Source: International Journal of Environmental Research and Public Health - March 14, 2018 Category: Environmental Health Authors: Chien-Hua Chen Cheng-Li Lin Chia-Hung Kao Tags: Article Source Type: research
