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Condition: Diabetes
Nutrition: Vitamins

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Total 434 results found since Jan 2013.

Reduced thiamine is a predictor for cognitive impairment of cerebral infarction
ConclusionsReduced thiamine is one of the predictors for early cognitive impairment in patients with acute cerebral infarction.
Source: Brain and Behavior - August 4, 2020 Category: Neurology Authors: Liang Feng, Weilei He, Guiqian Huang, Shasha Lin, Chengxiang Yuan, Haoran Cheng, Jincai He, Yiming Liu Tags: ORIGINAL RESEARCH Source Type: research

Different Risk Profiles of European Patients Using Direct Oral Anticoagulants or Vitamin K Antagonists: a Rapid Review
AbstractPurpose of ReviewWe investigated the risk profiles of patients using direct oral anticoagulants (DOAC) or vitamin K antagonists (VKA) in European cohort studies to estimate the importance of potential (measured or unmeasured) confounding factors in analyses comparing these drugs. We searched MEDLINE and EMBASE (2008 –2018) for relevant studies and extracted information on age, sex, comorbidity, Charlson comorbidity index, HAS-BLED score (assessing risk of bleeding) and CHA2DS2-VASc score (assessing risk of stroke).Recent FindingsOverall, 66 studies with 2,808,757 patients were included. Most patients were from Fr...
Source: Current Epidemiology Reports - November 14, 2020 Category: Epidemiology Source Type: research

Comparative effectiveness and safety of non-vitamin k antagonist oral anticoagulants and warfarin in older adults with atrial fibrillation and diabetes.
CONCLUSION: Oral anticoagulation therapy with NOACs was found to be more effective than warfarin therapy among older adults with NVAF and comorbid DM. PMID: 33327796 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - December 18, 2020 Category: Research Tags: Curr Med Res Opin Source Type: research

Clinical Outcome in Patients With Intracerebral Hemorrhage Stratified by Type of Antithrombotic Therapy
Conclusions: Patients with antithrombotic therapy have worse clinical outcome after ICH. Patients using VKA have higher risk of poor outcome and mortality compared to patients using AP. These findings highlight the deleterious effect of antithrombotic therapy in patients with ICH and stress the need for effective therapies for ICH patients.
Source: Frontiers in Neurology - June 7, 2021 Category: Neurology Source Type: research

Oral anticoagulation for patients with atrial fibrillation in the ED: RE-LY AF registry analysis
AbstractOral anticoagulation (OAC) reduces stroke risk in patients with atrial fibrillation (AF). We sought to determine predictors of OAC initiation in AF patients presenting to the emergency department (ED). Secondary analysis of the RE-LY AF registry which enrolled individuals from 47 countries between 2007 and 2011 who presented to an ED with AF and followed them for 1  year. A total of 4149 patients with AF as their primary diagnosis who were not already taking OAC and had a CHA2DS2-VASc  ≥ 1 for men or ≥ 2 for women were included in this analysis. Of these individuals, 26.8% were started on OAC (99.2% vi...
Source: Journal of Thrombosis and Thrombolysis - August 2, 2021 Category: Hematology Source Type: research

Direct Oral Anticoagulants in Cardiac Amyloidosis –Associated Heart Failure and Atrial Fibrillation
Atrial fibrillation (AF) is present in approximately 40% of patients with cardiac amyloidosis.1 AF in the setting of cardiac amyloidosis is associated with a significant risk of stroke and systemic thromboembolism regardless of the patient's CHA ₂DS₂-VASc (congestive heart failure, hypertension, age ≥ 75 years, diabetes mellitus, stroke or transient ischemic attack, vascular disease, age 65 to 74 years, sex category) score.2 Although current guidelines recommend anticoagulation therapy in all patients with cardiac amyloidosis and AF, data about the comparative effectiveness and safety of vitamin K antagonists (VKAs) ...
Source: The American Journal of Cardiology - November 27, 2021 Category: Cardiology Authors: Amgad Mentias, Paulino Alvarez, Pulkit Chaudhury, Michael Nakhla, Rohit Moudgil, Mohamad Kanj, Mazen Hanna, Milind Y. Desai Source Type: research

Eating your 5 A DAY 'could make you more optimistic'
Conclusion This is well-conducted research which has used a validated measure to assess the optimism of a sample of middle-aged American citizens and measure their blood antioxidant levels. The researchers found a link between higher carotenoid levels and higher optimism, but as the researchers rightly conclude, their findings do not prove cause and effect and it isn’t possible to say in which direction the relationship is going. It is possible that having higher levels of antioxidants in the body leads to better physical health and this in turn enhances optimism, but then it is equally possible that people who are in be...
Source: NHS News Feed - January 18, 2013 Category: Consumer Health News Tags: Food/diet Mental health Source Type: news

The world pandemic of Vitamin D deficit could possibly be explained by cellular inflammatory response activity induced by the renin angiotensin system.
Abstract This review attempts to show that there may be a relationship between inflammatory processes induced by chronic overstimulation of the renin angiotensin system (RAS) and the worldwide vitamin D (VitD) deficiency, and probably both disorders are associated with environmental factors. Low VitD levels represent a risk factor for several apparently different diseases such as infectious, autoimmune, neurodegenerative, and cardiovascular diseases, as well as diabetes, osteoporosis, and cancer. Moreover, VitD insufficiency seems to predispose hypertension, metabolic syndrome, left ventricular hypertrophy, heart ...
Source: American Journal of Physiology. Cell Physiology - January 30, 2013 Category: Cytology Authors: Ferder M, Inserra F, Manucha W, Ferder L Tags: Am J Physiol Cell Physiol Source Type: research

Influence of dietary patterns on the risk of acute myocardial infarction in China population: the INTERHEART China study.
CONCLUSIONS: Unhealthy dietary intake can increase the AMI risk. Improving intake of vegetables, fruits and tofu have the potential to partially prevent the rising epidemic of cardiovascular disease in China. PMID: 23422108 [PubMed - in process]
Source: Chinese Medical Journal - February 1, 2013 Category: Journals (General) Authors: Guo J, Li W, Wang Y, Chen T, Teo K, Liu LS, Yusuf S, INTERHEART China study investigators Tags: Chin Med J (Engl) Source Type: research

Advanced glycation end products accelerate rat vascular calcification through RAGE/oxidative stress
Conclusions: These results suggest that AGEs enhance vascular calcification partly through a RAGE/oxidative stress pathway.
Source: BMC Cardiovascular Disorders - March 5, 2013 Category: Cardiology Authors: Qin WeiXiaomei RenYibo JiangHong JinNaifeng LiuJie Li Source Type: research

Serum vitamin D deficiency and its association with systemic disease in exfoliation syndrome.
Conclusions: Although vitamin D levels were similar between XFS and control subjects, the levels were found to be decreased in both groups. Patients with XFS had a significantly higher prevalence of cerebrovascular and cardiovascular disease as compared to controls independent of their 
serum 25(OH) D levels. Low vitamin D level does not appear to be linked to XFS in the studied population. PMID: 23564611 [PubMed - as supplied by publisher]
Source: European Journal of Ophthalmology - April 8, 2013 Category: Opthalmology Authors: Kocabeyoglu S, Mocan MC, Irkec M, Pinar A, Bozkurt B, Orhan M Tags: Eur J Ophthalmol Source Type: research

The world pandemic of vitamin D deficiency could possibly be explained by cellular inflammatory response activity induced by the renin-angiotensin system
This review attempts to show that there may be a relationship between inflammatory processes induced by chronic overstimulation of the renin-angiotensin system (RAS) and the worldwide deficiency of vitamin D (VitD) and that both disorders are probably associated with environmental factors. Low VitD levels represent a risk factor for several apparently different diseases, such as infectious, autoimmune, neurodegenerative, and cardiovascular diseases, as well as diabetes, osteoporosis, and cancer. Moreover, VitD insufficiency seems to predispose to hypertension, metabolic syndrome, left ventricular hypertrophy, heart failure...
Source: AJP: Cell Physiology - June 1, 2013 Category: Cytology Authors: Ferder, M., Inserra, F., Manucha, W., Ferder, L. Tags: REVIEW Source Type: research

Increased Risk of Cognitive Impairment in Patients With Diabetes Is Associated With Metformin.
CONCLUSIONSMetformin use was associated with impaired cognitive performance. Vitamin B12 and calcium supplements may alleviate metformin-induced vitamin B12 deficiency and were associated with better cognitive outcomes. Prospective trials are warranted to assess the beneficial effects of vitamin B12 and calcium use on cognition in older people with diabetes who are taking metformin. PMID: 24009301 [PubMed - as supplied by publisher]
Source: Diabetes Care - September 5, 2013 Category: Endocrinology Authors: Moore EM, Mander AG, Ames D, Kotowicz MA, Carne RP, Brodaty H, Woodward M, Boundy K, Ellis KA, Bush AI, Faux NG, Martins R, Szoeke C, Rowe C, Watters DA, the AIBL Investigators Tags: Diabetes Care Source Type: research

Metabolic Syndrome and Non-Cardiac Vascular Diseases: an Update from Human Studies.
Abstract The metabolic syndrome (MetS) is characterized by a cluster of risk factors including central obesity, hypertension, dyslipidemia and insulin resistance, The MetS is associated with an increased risk for cardiovascular disease (CVD) and type 2 diabetes mellitus (T2DM). Several international organizations have defined MetS using different diagnostic criteria that produced discrepancies in the results of previous studies, thus leading to the latest Joint Interim Societies (JIS) MetS definition. Other risk factors than the diagnostic criteria that have been associated with MetS include lipid abnormalities, u...
Source: Current Pharmaceutical Design - December 5, 2013 Category: Drugs & Pharmacology Authors: Katsiki N, Athyros VG, Karagiannis A, Mikhailidis DP Tags: Curr Pharm Des Source Type: research

Future Trials Unlikely to Support Vitamin D Supplementation Future Trials Unlikely to Support Vitamin D Supplementation
Should healthy older people take vitamin-D supplements to ward off MI, stroke, or cancer? Are more trials needed to investigate this? Researchers say no to both questions, in a new analysis. Medscape Medical News
Source: Medscape Diabetes Headlines - January 24, 2014 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news