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Hypertensive Retinopathy and Risk of Stroke Hypertensive Retinopathy
In this study, we examine whether hypertensive retinopathy predicts the long-term risk of stroke in those with hypertension. A total of 2907 participants with hypertension aged 50 to 73 years at the 1993 to 1995 examination, who had gradable retinal photographs, no history of diabetes mellitus, stroke, and coronary heart disease at baseline and data on incident stroke, were included from the Atherosclerosis Risk in Communities (ARIC) Study. Retinal photographs were assessed for hypertensive retinopathy signs and classified as none, mild, and moderate/severe. Incident events of any stroke, cerebral infarction, and hemorrhag...
Source: Hypertension - September 11, 2013 Category: Cardiology Authors: Ong, Y.-T., Wong, T. Y., Klein, R., Klein, B. E. K., Mitchell, P., Sharrett, A. R., Couper, D. J., Ikram, M. K. Tags: Cerebrovascular disease/stroke, Acute Cerebral Infarction, Risk Factors for Stroke Hypertensive Retinopathy Source Type: research

Incidence and Cost of Stroke and Hemorrhage in Patients Diagnosed with Atrial Fibrillation in France
Conclusions: The incidence and cost of hospitalization for hemorrhage should be considered in the global burden of AF. These data should be useful for pharmacoeconomic evaluation of new oral anticoagulant medications. Such real-world studies may be relevant for monitoring mid- to long-term morbidity and mortality in the AF population.
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2013 Category: Neurology Authors: François-Emery Cotté, Gwendoline Chaize, Isabelle Kachaner, Anne-Françoise Gaudin, Alexandre Vainchtock, Isabelle Durand-Zaleski Tags: Original Articles Source Type: research

Stroke Risk Factors, Subtypes, and 30-Day Case Fatality in Abuja, Nigeria (P1.121)
CONCLUSIONS: Although hypertension, obesity, diabetes mellitus, and atrial fibrillation were important stroke risk factors, in many patients, these were detected only after a stroke. While the commonest stroke subtype was cerebral infarction, observed in almost two-third of patients, SAH was associated with the highest case-fatality rate at 30 days of 44.4%. Larger population-based studies are planned.Study Supported by: nilDisclosure: Dr. Bwala has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Bwala, S. Tags: Cerebrovascular Disease and Interventional Neurology: Ischemic Stroke Subtype Source Type: research

Compare The Weekend Effect In Telestroke And Primary Stroke Center. (P3.127)
Conclusion: Implementation of telemedicine markedly increased the use of thrombolysis, without compromising favorable outcomes over the weekends.Disclosure: Dr. Mahuwala has nothing to disclose. Dr. Patel has nothing to disclose. Dr. Limaye has nothing to disclose. Dr. Hinduja has nothing to disclose. Dr. Bianchi has nothing to disclose. Dr. Patel has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Mahuwala, Z., Patel, A., Limaye, K., Hinduja, A., Bianchi, N., Patel, R. Tags: Cerebrovascular Disease and Interventional Neurology: Primary and Comprehensive Stroke Centers Source Type: research

Stroke in Patients With Aortic Stenosis: The Simvastatin and Ezetimibe in Aortic Stenosis Study Clinical Sciences
Conclusions— In patients with aortic stenosis not prescribed oral anticoagulation, atrial fibrillation, AVR with concomitant coronary artery bypass grafting, and CHA2DS2-VASc score were the major predictors of stroke. Incident stroke was strongly associated with mortality. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00092677.
Source: Stroke - June 23, 2014 Category: Neurology Authors: Greve, A. M., Dalsgaard, M., Bang, C. N., Egstrup, K., Ray, S., Boman, K., Rossebo, A. B., Gohlke-Baerwolf, C., Devereux, R. B., Kober, L., Wachtell, K. Tags: Thrombosis risk factors, CV surgery: valvular disease, Acute Cerebral Infarction Clinical Sciences Source Type: research

Women Had Worse Stroke Outcome (P1.217)
Conclusion: in our cohort women have worst post-stroke outcome, even though they have higher burden of vascular risk factors they have lower prevalence of vascular disease in other vascular beds previous to stroke. This difference persists after adjusting by age, raising the possibility of specific gender risk factors influencing on ischemic stroke outcomes.Disclosure: Dr. Zurru has nothing to disclose. Dr. Colla Machado has nothing to disclose. Dr. Alonzo has nothing to disclose. Dr. Brescacin has nothing to disclose. Dr. Luzzi has nothing to disclose. Dr. Pigretti has nothing to disclose. Dr. Balian has nothing to disclo...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Zurru, M., Colla Machado, P., Alonzo, C., Brescacin, L., Luzzi, A., Pigretti, S., Balian, N., Waisman, G., Cristiano, E. Tags: Re-admission and Stroke Outcomes Source Type: research

Lifetime direct costs of stroke for indigenous patients adjusted for comorbidities
Conclusions: The costs of stroke for indigenous people and patients with different comorbidities are substantial and an integrated prevention strategy is needed.
Source: Neurology - July 31, 2016 Category: Neurology Authors: Zhao, Y., Condon, J., Lawton, P., He, V., Cadilhac, D. A. Tags: Cost effectiveness/economic, All Cerebrovascular disease/Stroke, Cohort studies ARTICLE Source Type: research

Early Carotid Revascularization Reduces Readmission for Recurrent Ischemic Stroke in Acute Ischemic Stroke Patients: Analysis of United States Nationwide Readmissions Database (P4.294)
Conclusions:Patients with ischemic stroke undergoing carotid revascularization during the initial hospitalization have significantly lower risk of readmission related to another ischemic strokeDisclosure: Dr. Chaudhry has nothing to disclose. Dr. Gheith has nothing to disclose. Dr. Gu has nothing to disclose. Dr. Afzal has nothing to disclose. Dr. Rahman has nothing to disclose. Dr. Riaz has nothing to disclose. Dr. Sachdeva has nothing to disclose. Dr. Sattar has nothing to disclose. Dr. Razak has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Chaudhry, S., Gheith, T., Gu, S., Afzal, M.-R., Rahman, H., Riaz, A., Sachdeva, G., Sattar, A., Razak, A., Qureshi, A. Tags: In-Hospital Stroke Care Source Type: research

Delayed rFGF21 Administration Improves Cerebrovascular Remodeling and White Matter Repair After Focal Stroke in Diabetic Mice
This study aims to evaluate the potential effects of rFGF21 on cerebrovascular remodeling after T2DM stroke. Permanent distal middle cerebral artery occlusion was performed in heterozygous non-diabetic db/  + and homozygous diabetic db/db mice. Daily rFGF21 administration was initiated 1 week after stroke induction and maintained for up to 2 weeks thereafter. Multiple markers associated with post-stroke recovery, including angiogenesis, oligodendrogenesis, white matter integrity, and neurogenesi s, were assessed up to 3 weeks after stroke. Our results showed an impairment in post-stroke vascular remodeling under T2D...
Source: Translational Stroke Research - March 14, 2022 Category: Neurology Source Type: research

Population-Based Case-Control Study of White Matter Changes on Brain Imaging in Transient Ischemic Attack and Ischemic Stroke Clinical Sciences
Conclusions— In contrast to small vessel ischemic events, WMC were not independently associated with other pathogenic subtypes, suggesting that WMC are unlikely to be an independent risk factor for nonsmall vessel events.
Source: Stroke - October 21, 2013 Category: Neurology Authors: Li, L., Simoni, M., Kuker, W., Schulz, U. G., Christie, S., Wilcock, G. K., Rothwell, P. M. Tags: Computerized tomography and Magnetic Resonance Imaging, Epidemiology Clinical Sciences Source Type: research

Gender differences in the age‐stratified prevalence of risk factors in Korean ischemic stroke patients: a nationwide stroke registry‐based cross‐sectional study
ConclusionKorean women with stroke had more hypertension and hyperlipidemia after middle age, more diabetes after 65 years, and more atrial fibrillation throughout all ages. Strategies to control risk factors in women at risk for stroke are eagerly needed.
Source: International Journal of Stroke - October 22, 2013 Category: Neurology Authors: Tai Hwan Park, Youngchai Ko, Soo Joo Lee, Kyung Bok Lee, Jun Lee, Moon‐Ku Han, Jong‐Moo Park, Dong‐Eog Kim, Yong‐Jin Cho, Keun‐Sik Hong, Joon‐Tae Kim, Ki‐Hyun Cho, Dae‐Hyun Kim, Jae‐Kwan Cha, Kyung‐Ho Yu, Byung‐Chul Lee, Byung‐Woo Tags: Research Source Type: research

Transition of European Cooperative Acute Stroke Study III Results to Clinical Practice: Ninety-Day Outcomes in a US Cohort Brief Reports
Conclusions— For patients treated with intravenous tissue-type plasminogen activator 3 to 4.5 hours from onset in everyday practice in the United States, there is no evidence for increased risk or worse outcomes compared with standard treatment ≤3 hours.
Source: Stroke - November 25, 2013 Category: Neurology Authors: Cronin, C. A., Langenberg, P., Dutta, T. M., Kittner, S. J. Tags: Brief Reports Source Type: research

Risk of Metabolic Syndrome for Stroke Is Not Greater than the Sum of its Components: Thai Epidemiologic Stroke (TES) Study
This study aimed to assess the association of MetS with stroke, and to evaluate whether the risk of MetS is greater than the sum of its components. The Thai Epidemiologic Stroke (TES) study is a community-based cohort study with 19,997 participants, aged 45-80 years, recruited from the general population from 5 regions of Thailand. Baseline survey data were analyzed in cross-sectional analyses. MetS was defined according to criteria from the National Cholesterol Education Program (NCEP) Adult Treatment Panel III, the American Heart Association/National Heart, Lung, and Blood Institute (revised NCEP), and International Diab...
Source: Journal of Stroke and Cerebrovascular Diseases - June 29, 2012 Category: Neurology Authors: Suchat Hanchaiphiboolkul, Nijasri Charnnarong Suwanwela, Niphon Poungvarin, Samart Nidhinandana, Pimchanok Puthkhao, Somchai Towanabut, Tasanee Tantirittisak, Jithanorm Suwantamee, Maiyadhaj Samsen Tags: Original Articles Source Type: research

Plasma free fatty acids and risk of stroke in the Cardiovascular Health Study
ConclusionOur data did not show an association of plasma free fatty acids with incident stroke among community dwelling older adults.
Source: International Journal of Stroke - January 21, 2014 Category: Neurology Authors: Owais Khawaja, Marlena Maziarz, Mary L. Biggs, William T. Longstreth, Joachim H. Ix, Jorge R. Kizer, Susan Zieman, Russell P. Tracy, Dariush Mozaffarian, Kenneth J. Mukamal, David S. Siscovick, Luc Djoussé Tags: Research Source Type: research

Intravenous Thrombolysis for Acute Ischemic Stroke in the 3- to 4{middle dot}5-Hour Window - The Malabar Experience (P4.224)
CONCLUSIONS: Our initial experience confirms that thrombolysis for ischemic stroke in the extended window is safe and beneficial.Disclosure: Dr. Ummer has nothing to disclose. Dr. Salam has nothing to disclose. Dr. Noone has nothing to disclose. Dr. Kumar has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Ummer, K., Salam, K., Noone, M., Kumar, P. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Stroke Thrombolysis Source Type: research