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Risk Factors and Outcomes of Cerebral Stroke in End-Stage Renal Disease Patients Receiving Hemodialysis
This study investigated the stroke features and risk factors in hemodialysis (HD) patients. Methods: All end-stage renal disease patients undergoing HD at Teraoka Memorial Hospital dialysis center were identified, with 195 recruited. Baseline clinical characteristics were collected, and the clinical outcomes and related factors of stroke in HD patients were retrospectively analyzed.
Source: Journal of Stroke and Cerebrovascular Diseases - February 5, 2020 Category: Neurology Authors: Yuki Shinya, Satoru Miyawaki, Isao Kumagai, Takehiro Sugiyama, Atsumi Takenobu, Nobuhito Saito, Akira Teraoka Source Type: research

Do all gliflozins reduce stroke in patients with type 2 diabetes mellitus and impaired renal function?
We have read with great interest a study of meta-analysis1 recently published in Journal of Stroke and Cerebrovascular Diseases. In that study1 Barkas and colleagues drew their main conclusion that sodium-glucose transporter 2 (SGLT2) inhibitors reduce the risk of total stroke in patients with type 2 diabetes mellitus (T2DM) and impaired renal function (IRF), which was based on the result of meta-analysis on the outcome of total stroke (including ischemic and hemorrhagic stroke) in the subgroup of patients with T2DM and IRF (Fig.
Source: Journal of Stroke and Cerebrovascular Diseases - April 17, 2021 Category: Neurology Authors: Li-Min Zhao, Liang-Liang Ding, Ze-Lin Zhan, Mei Qiu Tags: Letter to the Editor Source Type: research

Understanding Coordinator Roles in Acute Stroke Care: A National Survey
Globally, stroke is a major contributor to death and disability.1 Evidence-based care in hospital after an acute stroke ensures improved survival and reduced disability, but care quality can vary.2,3 Clinical coordinators have an essential role in improving best-practice in trauma, cancer, diabetes, and heart failure conditions.4-7 Within stroke, coordinator roles are not new; in 1970, a study outlining the ‘Stroke Team’ model was published, which included a physician, nurse-coordinator and physical therapist.
Source: Journal of Stroke and Cerebrovascular Diseases - September 29, 2021 Category: Neurology Authors: Tara Purvis, Sandy Middleton, Anne W. Alexandrov, Monique F. Kilkenny, Skye Coote, Sarah Kuhle, Dominique A. Cadilhac Source Type: research

Variation in Knowledge of Stroke Warning Signs by Age and Presence of Conventional Risk Factors: A Community Health Survey in Korea
Conclusion Stoke risk factors are increasing among young people; they still have poor knowledge about SWSs. More education is needed to increase appropriate treatment, especially in young people with stroke-related risk factors.
Source: Journal of Cardiovascular Nursing - February 11, 2022 Category: Nursing Tags: ARTICLES: Stroke Care Source Type: research

Predictors of futile recanalization after endovascular treatment in acute ischemic stroke: a meta-analysis
Conclusion This study identified female sex, comorbidities, admission systolic blood pressure, serum glucose, occlusion site, non-bridging therapy, and post-procedural complication as predictors of futile recanalization, and also confirmed previously reported factors. Further large-scale prospective studies are needed.
Source: Journal of NeuroInterventional Surgery - August 12, 2022 Category: Neurosurgery Authors: Deng, G., Xiao, J., Yu, H., Chen, M., Shang, K., Qin, C., Tian, D.-S. Tags: Ischemic stroke Source Type: research

Risk of New-onset Stroke in Patients with Type 2 Diabetes with Chronic Kidney Disease on Sodium-glucose Co-transporter-2 Inhibitor Users
This study aimed to examine the association between the use of SGLT2 inhibitors and NOS risk in patients with T2D and CKD. We conducted a nationwide retrospective cohort study using data from the Taiwan Health Insurance Review and Assessment Service database for the years 2004 to 2019. The primary outcome was the risk of incident stroke, which was estimated using hazard ratios (HRs) and 95% confidence intervals (CIs). We used multiple Cox regression modeling to analyze the association between SGLT2 inhibitor use and the risk of stroke in patients with T2D and CKD. In a cohort of 113,710 patients with T2D and CKD who were u...
Source: Translational Stroke Research - July 14, 2023 Category: Neurology Source Type: research

Predictors for Recurrent Primary Intracerebral Hemorrhage: A Retrospective Population-based Study Clinical Sciences
Conclusions— Previous ischemic stroke independent of confounding factors may increase the risk for PICH recurrence.
Source: Stroke - February 25, 2013 Category: Neurology Authors: Huhtakangas, J., Lopponen, P., Tetri, S., Juvela, S., Saloheimo, P., Bode, M. K., Hillbom, M. Tags: Health policy and outcome research, Acute Cerebral Hemorrhage, Intracerebral Hemorrhage, Risk Factors for Stroke Clinical Sciences Source Type: research

Elevated thyroid autoantibodies and intracranial stenosis in stroke at an early age
ConclusionsThyroid autoantibodies may be associated with the presence of intracranial large artery stenosis in young stroke patients, potentially providing insight on immune pathogenesis of intracranial large artery stenosis.
Source: International Journal of Stroke - September 12, 2013 Category: Neurology Authors: Zhenghao Shi, Xuting Zhang, Zhicai Chen, David S Liebeskind, Min Lou Tags: Research Source Type: research

Intervention Stroke Assessment Scale for Eligibility in Endovascular Therapy (ISAS-ET) (P4.213)
Conclusion:In conclusion, the ISAS scoring system might help with the assessment of patient qualification for further endovascular treatment. Further prospective studies are warranted.Disclosure: Dr. Haitham has nothing to disclose. Dr. Bashir has nothing to disclose. Dr. Hussain has nothing to disclose. Dr. Misthal has nothing to disclose. Dr. Moussavi has nothing to disclose. Dr. Kirmani has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Haitham, D., Bashir, A., Hussain, M., Misthal, S., Moussavi, M., Kirmani, J. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Stroke Endovascular Source Type: research

Risk Factors and Clinical Outcomes Associated with Intracranial and Extracranial Atherosclerotic Stenosis Acute Ischemic Stroke
Background: The aim of this study was to investigate differences in risk factors, lipid profiles, mortality, and poor functional outcome in the long term in patients who had stroke associated with intracranial and/or extracranial atherosclerotic stenosis.Methods: We consecutively and prospectively enrolled patients admitted to our hospital with acute ischemic stroke. Included patients were classified into 4 groups based on stroke subtype: noncerebral artery stenosis (NCAS), intracranial stenosis (IS), extracranial stenosis (ES), and combined intracranial and extracranial stenosis (IES). Risk factors, lipid profiles, mortal...
Source: Journal of Stroke and Cerebrovascular Diseases - November 4, 2013 Category: Neurology Authors: Chunyan Lei, Bo Wu, Ming Liu, Yanchao Chen Tags: Original Articles Source Type: research

The golden hour of stroke intervention: effect of thrombectomy procedural time in acute ischemic stroke on outcome
Conclusions Our findings suggest that extending mechanical thrombectomy procedure times beyond 60 min increases complications and device cost rates while worsening outcomes. These findings can serve as a time frame of when it is prudent to abort a failed thrombectomy case.
Source: Journal of NeuroInterventional Surgery - August 6, 2014 Category: Neurosurgery Authors: Spiotta, A. M., Vargas, J., Turner, R., Chaudry, M. I., Battenhouse, H., Turk, A. S. Tags: Ischemic stroke Source Type: research

Protocol for Cilostazol Stroke Prevention Study for Antiplatelet Combination (CSPS.com): a randomized, open‐label, parallel‐group trial
DiscussionThe CSPS.com is expected to provide evidence indicating whether secondary IS prevention in high‐risk patients can be improved by using DAPT involving cilostazol.
Source: International Journal of Stroke - December 8, 2014 Category: Neurology Authors: Kazunori Toyoda, Shinichiro Uchiyama, Haruhiko Hoshino, Kazumi Kimura, Hideki Origasa, Hiroaki Naritomi, Kazuo Minematsu, Takenori Yamaguchi, Tags: Protocols Source Type: research

Circulating Atrial Natriuretic Peptide Genetic Association Study Identifies a Novel Gene Cluster Associated With Stroke in Whites Original Articles
Conclusions— This is the first large-scale genetic association study of circulating NT-proANP levels performed with replication and functional assessment that identified genetic variants in the MTHFR-CLCN6-NPPA-NPPB cluster to be significantly associated with NT-proANP levels. The clinical significance of this variation is related to lower NT-proANP levels, higher blood pressures, and an increased risk of stroke in the general community.
Source: Circulation: Cardiovascular Genetics - February 17, 2015 Category: Cardiology Authors: Pereira, N. L., Tosakulwong, N., Scott, C. G., Jenkins, G. D., Prodduturi, N., Chai, Y., Olson, T. M., Rodeheffer, R. J., Redfield, M. M., Weinshilboum, R. M., Burnett, J. C. Tags: Cardio-renal physiology/pathophysiology, Cerebrovascular disease/stroke, Genetics of Stroke, Epidemiology, Genetics of cardiovascular disease Original Articles Source Type: research

White matter lesion volume reduces fine motor skills: Is primary stroke prophylaxis warranted?
Neuroimaging, particularly cerebral MRI, frequently demonstrates white matter lesions (WMLs) in the elderly and patients with vascular risk factors such as arterial hypertension and diabetes. WMLs may result from ischemia associated with atherosclerosis of perforating arteries and arteriolar degeneration due to fibrohyalinosis.1,2 They can appear silently, but are an important risk factor for the development of stroke, mainly ischemic stroke.3 Moreover, WMLs are linked to the development of cognitive impairment and dementia.4,5
Source: Neurology - May 11, 2015 Category: Neurology Authors: Wartenberg, K. E., Lorenzano, S. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Vascular dementia, Prevalence studies, Risk factors in epidemiology EDITORIALS Source Type: research

Sex Differences in Outcomes and Associated Risk Factors After Acute Ischemic Stroke in Elderly Patients: A Prospective Follow-up Study
Stroke has a greater effect on women. However, sex differences in outcome and factors associated with outcome among elderly patients are unknown. From January 2009 to December 2011, 810 patients with acute ischemic stroke aged 75 years or older were recruited in China. Clinical profile and risk factors were recorded. Outcomes and associated risk factors at 12 and 36 months after stroke were assessed by sex. Hypertension, diabetes mellitus, dyslipidemias, and obesity prevalence rates were higher in women than in men; opposite trends were found for smoking and alcohol consumption.
Source: Journal of Stroke and Cerebrovascular Diseases - July 10, 2015 Category: Neurology Authors: Bin Li, Tao Wang, Yongzhong Lou, Xiaofei Guo, Hongfei Gu, Yanxia Zhu, Xianjia Ning, Jinghua Wang, Jun Tu Source Type: research