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Condition: Reflex Sympathetic Dystrophy

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Total 1447 results found since Jan 2013.

Values of vanillylmandelic acid and homovanillic acid in the urine as potential prognostic biomarkers in ischaemic stroke patients.
CONCLUSION: Determining the values of these compounds in the urine is an easily available prognostic tool for the ischaemic stroke outcome, while also influencing potential therapeutic changes. PMID: 28675313 [PubMed - as supplied by publisher]
Source: Biomarkers - July 5, 2017 Category: Research Tags: Biomarkers Source Type: research

Glucocorticoids Regulate Bone Marrow B Lymphopoiesis After Stroke.
CONCLUSIONS: Our data demonstrate that the hypothalamic-pituitary-adrenal axis mediates B lymphopoiesis defects after ischemic stroke. PMID: 30782088 [PubMed - as supplied by publisher]
Source: Circulation Research - February 20, 2019 Category: Cardiology Authors: Courties G, Frodermann V, Honold L, Zheng Y, Herisson FE, Schloss MJ, Sun Y, Presumey J, Severe N, Engblom C, Hulsmans M, Cremer S, Rohde D, Pittet MJ, Scadden D, Swirski FK, Kim DE, Moskowitz MA, Nahrendorf M Tags: Circ Res Source Type: research

Cardiac autonomic dynamics during sleep are lost in patients with TIA and stroke.
Abstract Ischaemic stroke is accompanied by important alterations of cardiac autonomic control, which have an impact on stroke outcome. In sleep, cardiac autonomic control oscillates with a predominant sympathetic modulation during REM sleep. We aimed to assess cardiac autonomic control in different sleep stages in patients with ischaemic stroke. Forty-five patients enrolled in the prospective, multicentre SAS-CARE study but without significant sleep-disordered breathing (apnea-hypopnea index < 15/hr) and without atrial fibrillation were included in this analysis. The mean age was 56 years, 68% were male, 76...
Source: Journal of Sleep Research - June 12, 2019 Category: Sleep Medicine Authors: Tobaldini E, Proserpio P, Oppo V, Figorilli M, Fiorelli EM, Manconi M, Agostoni EC, Nobili L, Montano N, Horvath T, Bassetti CL Tags: J Sleep Res Source Type: research

Immune Alterations Following Neurological Disorders: A Comparison of Stroke and Seizures
Conclusion: Seizures lead to immune alterations within the immediate postictal period similar but not identical to stroke. The type of seizures determines the extent of immune alterations.
Source: Frontiers in Neurology - June 1, 2020 Category: Neurology Source Type: research

The endogenous and exogenous brain-derived neurotrophic factor plays pivotal roles in the pathogenesis of stroke onset in high salt-loaded hypertensive rats.
Abstract Brain-derived neurotrophic factor (BDNF) is known to have neuroprotective effects on multiple neurovascular diseases especially poststroke recovery. On the other hand, BDNF reported to increase blood pressure (BP) which is one of the major risk factor for stroke onset. To clarify the conflicting effects on stroke onset, we examined the expression of endogenous BDNF in relation to stroke onset. In addition, we explored the effect of exogenous central BDNF against stroke onset and all-cause mortality as the primary endpoint and BP as the secondary object in hypertensive rats with high-salt diet. In experime...
Source: Experimental Gerontology - February 17, 2021 Category: Geriatrics Authors: Hasegawa Y, Takemoto Y, Hayashi K, Kameno K, Kim-Mitsuyama S Tags: Exp Gerontol Source Type: research

Longitudinal changes in the hypothalamic –pituitary–adrenal axis and sympathetic nervous system are related to the prognosis of stroke
ConclusionsStroke causes significant time-phased dynamic changes in the hypothalamic–pituitary–adrenal axis and sympathetic nervous system, and plasma F, ACTH, and urinary NE levels can be used to assess stroke severity and prognosis.Chinese clinical trial registryRegistration Number: ChiCTR1900024992. Registration Date: 2019/8/6.
Source: Frontiers in Neurology - July 27, 2022 Category: Neurology Source Type: research

Blocked angiogenesis in Galectin-3 null mice does not alter cellular and behavioral recovery after middle cerebral artery occlusion stroke.
Abstract Angiogenesis is thought to decrease stroke size and improve behavioral outcomes and therefore several clinical trials are seeking to augment it. Galectin-3 (Gal-3) expression increases after middle cerebral artery occlusion (MCAO) and has been proposed to limit damage 3days after stroke. We carried out mild MCAO that damages the striatum but spares the cerebral cortex and SVZ. Gal-3 gene deletion prevented vascular endothelial growth factor (VEGF) upregulation after MCAO. This inhibited post-MCAO increases in endothelial proliferation and angiogenesis in the striatum allowing us to uniquely address the fu...
Source: Neurobiology of Disease - November 21, 2013 Category: Neurology Authors: Young CC, Al-Dalahmah O, Lewis NJ, Brooks KJ, Jenkins MM, Poirier F, Buchan AM, Szele FG Tags: Neurobiol Dis Source Type: research

Relation of Serial Hemodynamic and Autonomic Changes in Acute Ischemic Stroke to Stroke Type, Location and Outcome. (P3.094)
Conclusion: Hypertension in AIS may be mediated predominantly by changes in SVR. Hemodynamic and autonomic parameters may predict outcome and possibly stroke location. Further studies among patients with homogenous stroke types may help understand the interaction between focal brain injury and autonomic changes.Study funded by: Dean's Fund, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, OmanDisclosure: Dr. Gujjar has nothing to disclose. Dr. Jaju has nothing to disclose. Dr. Poovathur has nothing to disclose. Dr. Dikshit has nothing to disclose. Dr. Al-Asmi has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Gujjar, A., Jaju, D., Poovathur, J., Dikshit, M., Al-Asmi, A. Tags: Cerebrovascular Disease and Interventional Neurology: Clinical Management Source Type: research

Differential effects of sympathetic nervous system and hypothalamic-pituitary-adrenal axis on systemic immune cells after severe experimental stroke.
In conclusion, mediators of the SNS and the HPA axis differentially affect the systemic immune system after stroke. Moreover, our findings suggest a negative-feedback of corticosteroids on the sympathetic axis which may control the post-stroke stress-reaction. This complex interplay between the HPA and the SNS after stroke has to be considered when targeting the neurohormonal systems in the post acute phase of severe stroke. PMID: 24886966 [PubMed - as supplied by publisher]
Source: Brain, Behavior, and Immunity - May 30, 2014 Category: Neurology Authors: Mracsko E, Liesz A, Karcher S, Zorn M, Bari F, Veltkamp R Tags: Brain Behav Immun Source Type: research

VOR Gain by Head Impulse Video-Oculography Differentiates Acute Vestibular Neuritis from Stroke
Conclusion: Video HIT VOR gains differ between peripheral and central causes of AVS. PICA strokes were readily separated from neuritis using gain measures, but AICA strokes were at risk of being misclassified based on VOR gain alone.
Source: Otology and Neurotology - February 13, 2015 Category: ENT & OMF Tags: Vestibular Disorders Source Type: research

Cough reflex attenuation and swallowing dysfunction in sub‐acute post‐stroke patients: prevalence, risk factors, and clinical outcome
ConclusionsPrevalence of subacute post‐stroke OD and swallow safety impairments was much higher than CRT attenuation, and risk factors strongly differed suggesting that the swallow response receives a stronger cortical control than the cough reflex. OD has a greater impact on PSP clinical outcome than impaired cough, the poorest prognosis being for patients with both airway protective dysfunctions. We found that the prevalence of OD was much higher than impairments in the CRT response. Neurotopographical and clinical stroke factors attenuated the CRT response but no specific risk factors for impaired CRT response were f...
Source: Neurogastroenterology and Motility - June 30, 2016 Category: Gastroenterology Authors: N. Vilardell, L. Rofes, W. V. Nascimento, D. Muriana, E. Palomeras, P. Clavé Tags: Original Article Source Type: research

Cough reflex attenuation and swallowing dysfunction in sub ‐acute post‐stroke patients: prevalence, risk factors, and clinical outcome
ConclusionsPrevalence of subacute post‐stroke OD and swallow safety impairments was much higher than CRT attenuation, and risk factors strongly differed suggesting that the swallow response receives a stronger cortical control than the cough reflex. OD has a greater impact on PSP clinical outcome than impaired cough, the poorest prognosis being for patients with both airway protective dysfunctions. We found that the prevalence of OD was much higher than impairments in the CRT response. Neurotopographical and clinical stroke factors attenuated the CRT response but no specific risk factors for impaired CRT response were f...
Source: Neurogastroenterology and Motility - July 17, 2016 Category: Gastroenterology Authors: N. Vilardell, L. Rofes, W. V. Nascimento, D. Muriana, E. Palomeras, P. Clav é Tags: Original Article Source Type: research

Pre-Stroke Use of Beta-Blockers Does Not Lower Post-Stroke Infection Rate: An Exploratory Analysis of the Preventive Antibiotics in Stroke Study
This study is aimed at investigating the association between BB treatment at baseline and post-stroke infection in the Preventive Antibiotics in Stroke Study (PASS), a prospective clinical trial.Methods: We performed an exploratory analysis in PASS, 2,538 patients with acute phase of stroke (24 h after onset) were randomized to ceftriaxone (intravenous, 2 g per day for 4 days) in addition to stroke unit care, or standard stroke unit care without preventive antibiotic treatment. All clinical data, including use of BBs, was prospectively collected. Infection was diagnosed by the treating physician, and independently by an ex...
Source: Cerebrovascular Diseases - October 4, 2016 Category: Neurology Source Type: research

Lower extremity long-latency reflexes differentiate walking function after stroke.
Abstract The neural mechanisms of walking impairment after stroke are not well characterized. Specifically, there is a need for understanding the mechanisms of impaired plantarflexor power generation in late stance. Here, we investigated the association between two neurophysiologic markers, the long-latency reflex (LLR) response and dynamic facilitation of antagonist motor-evoked responses, and walking function. Fourteen individuals with chronic post-stroke hemiparesis and thirteen healthy controls performed both isometric and dynamic plantarflexion. Transcranial magnetic stimulation (TMS) assessed supraspinal dri...
Source: Experimental Brain Research - July 31, 2019 Category: Neuroscience Authors: Banks CL, Little VL, Walker ER, Patten C Tags: Exp Brain Res Source Type: research

Impaired H-Reflex Adaptations Following Slope Walking in Individuals With Post-stroke Hemiparesis
ConclusionSimilar pattern of change in peak propulsive and braking forces with respect to different slopes was observed in both individuals post-stroke and non-impaired individuals, but the magnitude of GRFs were smaller in individuals post-stroke due to the slower walking speed. Our results suggested that impaired modulation of the H-reflex pathway potentially underlies the lack of neuroadaptations in individuals with chronic post-stroke hemiparesis.
Source: Frontiers in Physiology - September 30, 2019 Category: Physiology Source Type: research