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Condition: Metabolic Syndrome

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Total 926 results found since Jan 2013.

Cardiovascular disease due to accelerated atherosclerosis in systemic vasculitides
Patients with different forms of systemic vasculitis experience long-term morbidity and mortality caused by cardiovascular disease due to premature atherosclerosis.Epidemiologic reports of patients with GCA suggest that long-term mortality in this disease is not increased compared with the general population of the same age. The risk of a stroke, however, in particular in the vertebrobasilar territory, is increased. In addition, the occurrence of aortic aneurysmal disease and aortic dissection is also clearly increased in GCA. Mortality due to ischaemic heart disease, however, is not increased.In Takayasu arteritis acceler...
Source: Best Practice and Research. Clinical Rheumatology - February 1, 2013 Category: Rheumatology Authors: Jan Willem Cohen Tervaert Source Type: research

Interaction of smoking and metabolic syndrome on cardiovascular risk in a Chinese cohort
Conclusions: Both cigarette smoking and MS are strong risk factors of CVD in the Chinese population. Moreover, this study further demonstrates an additive interaction of current smoking and MS on cardiovascular risk.
Source: International Journal of Cardiology - January 16, 2012 Category: Cardiology Authors: Lijun Zhang, Zhirong Guo, Ming Wu, Xiaoshu Hu, Yanying Xu, Zhengyuan Zhou Tags: Original Articles Source Type: research

Are weekly workouts as good as daily exercise?
Conclusion This study used a large quantity of data from more than 2,000 participants of the Canadian Health Measures Survey to try to gauge how often adults should perform 150 minutes of exercise a week, as recommended by most guidelines. The main finding was that those who met this total physical activity requirement were less likely to have metabolic syndrome than those who were less active, which is not particularly surprising. Lack of exercise is associated with many of the risk factors for metabolic syndrome, such as obesity. Importantly, however, the frequency of time that MVPA was conducted over – whether this w...
Source: NHS News Feed - June 24, 2013 Category: Consumer Health News Source Type: news

What is metabolic syndrome? What causes metabolic syndrome?
Metabolic Syndrome, also known as Syndrome X, refers to a number of conditions that occur simultaneously and increase the risk of diabetes, stroke and heart disease. People with metabolic syndrome have high blood sugar levels, hypertension (high blood pressure), too much fat around their belly, and unhealthy cholesterol and triglyceride levels. Although on its own, each condition can raise the risk of heart attack or stroke, people with just one or two of them do not have metabolic syndrome. Metabolic syndrome is a preventable and reversible condition...
Source: Health News from Medical News Today - July 24, 2013 Category: Consumer Health News Tags: Obesity / Weight Loss / Fitness Source Type: news

Rationale and design of the Cardiovascular Inflammation Reduction Trial: A test of the inflammatory hypothesis of atherothrombosis
Background: Inflammation plays a fundamental role in atherothrombosis. Yet, whether direct inhibition of inflammation will reduce the occurrence of adverse cardiovascular outcomes is not known.Design: The Cardiovascular Inflammation Reduction Trial (CIRT) (ClinicalTrials.gov NCT01594333) will randomly allocate 7,000 patients with prior myocardial infarction (MI) and either type 2 diabetes or the metabolic syndrome to low-dose methotrexate (target dose 15-20 mg/wk) or placebo over an average follow-up period of 3 to 5 years. Low-dose methotrexate is a commonly used anti-inflammatory regimen for the treatment of rheumatoid a...
Source: American Heart Journal - May 6, 2013 Category: Cardiology Authors: Brendan M. Everett, Aruna D. Pradhan, Daniel H. Solomon, Nina Paynter, Jean MacFadyen, Elaine Zaharris, Milan Gupta, Michael Clearfield, Peter Libby, Ahmed A.K. Hasan, Robert J. Glynn, Paul M. Ridker Tags: Trial Design Source Type: research

Saturated fat link with heart disease questioned
This article is one doctor's opinion based on his own knowledge, research and experience. However, it is fair to say there is an ongoing debate about how far cholesterol is a risk factor for heart disease, especially in people who are otherwise healthy. There is also a similar debate about the use of statins in people who have no evidence of cardiovascular disease. This is alongside ongoing research into the components of LDL and the different types of lipoproteins known to increase risk the most. None of this relevant new evidence is covered by the news reporting.   What should you eat? There is no need to change curren...
Source: NHS News Feed - October 23, 2013 Category: Consumer Health News Tags: Heart/lungs Food/diet QA articles Source Type: news

Hyperandrogenic Oligomenorrhea and Metabolic Risks Across Menopausal Transition.
CONCLUSIONS: Longitudinal evidence suggests that a history of androgen excess and menstrual irregularity is not associated with worsening of metabolic health after menopause. Our findings challenge the notion that a history of concurrent HA and Oligo reflects ongoing cardiometabolic risk in postmenopausal women. PMID: 24517154 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - February 11, 2014 Category: Endocrinology Authors: Polotsky AJ, Allshouse AA, Crawford SL, Harlow SD, Khalil N, Kazlauskaite R, Santoro N, Legro RS Tags: J Clin Endocrinol Metab Source Type: research

Additive effect of the metabolic syndrome score to the conventional CHADS2 score for the thromboembolic risk stratification of patients with atrial fibrillation
Conclusions: We, for the first time, demonstrated that metabolic syndrome components were associated with thromboembolic risk in Taiwanese patients with AF. In addition to the conventional CHADS2 scheme, the calculation of the CHADS2-MS score provides additional information on stroke risk assessment.
Source: Heart Rhythm - November 18, 2013 Category: Cardiology Authors: Chia-Ti Tsai, Shu-Hsuan Chang, Sheng-Nan Chang, Juey-Jen Hwang, Cho-Kai Wu, Yi-Chih Wang, Chuen-Den Tseng, Huei-Ming Yeh, Ling-Ping Lai, Fu-Tien Chiang, Jiunn-Lee Lin Tags: Atrial Fibrillation Source Type: research

Eastern promises: Additive role of metabolic syndrome for thromboembolic risk stratification in Taiwanese atrial fibrillation patients
The key to prevention of stroke and other thromboembolic (TE) events in atrial fibrillation (AF) patients is effective risk stratification. Several schemes have been developed that use a combination of factors found to be associated with higher occurrence of TE events. Among the various risk stratification schemes, the CHADS2 (congestive heart failure, hypertension, age ≥75 years, diabetes, and prior history of stroke) scoring system is the most popular. Although the simplicity of this scoring system has resulted in its wide adoption, a major criticism has been its inability to consistently identify a truly low-risk grou...
Source: Heart Rhythm - December 6, 2013 Category: Cardiology Authors: Sanjay Dixit, Vinay Kini Tags: Editorial Commentary Source Type: research

Association between serum uric acid levels and cardiovascular disease in middle-aged and elderly Chinese individuals
This study sought to determine whether elevated serum uric acid levels are associated with cardiovascular disease (CVD) in middle-aged and elderly Chinese individuals. Methods: We conducted a population-based cross-sectional study in Shanghai, with a total of 8510 participants aged>=40 years. The CVD included diagnosed coronary heart disease (CHD) and stroke. MetS was defined according to the updated National Cholesterol Education Program Adult Treatment Panel III criteria for Asian Americans. Results: Uric acid levels were positively associated with BMI, waist circumference, triglycerides, systolic blood pressure, diastol...
Source: BMC Cardiovascular Disorders - February 25, 2014 Category: Cardiology Authors: Li QinZhen YangHongxia GuShuai LuQun ShiYin XingXiaoyong LiRui LiGuang NingQing Su Source Type: research

Chronic hepatitis C virus infection and atherosclerosis: Clinical impact and mechanisms.
Abstract Hepatitis C virus (HCV) infection represents a major health issue worldwide due to its burden of chronic liver disease and extrahepatic manifestations including cardiovascular diseases, which are associated with excess mortality. Analysis of published studies supports the view that HCV infection should be considered a risk factor for the development of carotid atherosclerosis, heart failure and stroke. In contrast, findings from studies addressing coronary artery disease and HCV have yielded conflicting results. Therefore, meta-analytic reviews and prospective studies are warranted. The pathogenic mechani...
Source: World Journal of Gastroenterology : WJG - April 7, 2014 Category: Gastroenterology Authors: Adinolfi LE, Zampino R, Restivo L, Lonardo A, Guerrera B, Marrone A, Nascimbeni F, Florio A, Loria P Tags: World J Gastroenterol Source Type: research

Assessment of college students' awareness and knowledge about conditions relevant to metabolic syndrome.
CONCLUSION: The findings in this study suggest that students' knowledge about conditions relevant to metabolic syndrome can be improved. In this essence, raising awareness about MetS based on students' pre-existing knowledge is essential to enhance students' wellness. PMID: 25360161 [PubMed]
Source: Diabetes Metab - November 4, 2014 Category: Endocrinology Authors: Yahia N, Brown C, Rapley M, Chung M Tags: Diabetol Metab Syndr Source Type: research

The Efficacy of Fimasartan for Cardiovascular Events and Metabolic Syndrome (K-MetS Study): Rationale, Design and Participant Characteristics
Fimasartan, the eighth angiotensin receptor blocker, was launched in March 2011 and was found to have an excellent efficacy and safety profile in a large cross-sectional population study [Safety and Efficacy of Fimasartan in Patients with Arterial Hypertension (Safe-KanArb); Park et al.: Am J Cardiovasc Drugs 2013;13:47-56]. However, there is no long-term study to evaluate its efficacy for major adverse cardiovascular events (MACE) and other effects. The purpose of this study (K-MetS study) was to evaluate whether the early reduction of blood pressure (BP) and/or correction of metabolic derangements with fimasartan will af...
Source: Pulse - November 6, 2014 Category: Cardiology Source Type: research

Hypertension in diabetes: optimal pharmacotherapy.
Authors: Biswas A, Alvarez A, Mukherjee D Abstract Hypertension is commonly associated with diabetes mellitus. The combination of hypertension with obesity and diabetes is a well recognized entity known as the metabolic syndrome, which shares a common pathophysiology of insulin resistance. The individual components of this syndrome act synergistically to substantially increase the risk of renal disease, stroke, coronary artery disease, and death. Hypertension increases both macrovascular and microvascular complications of diabetes such as neuropathy, nephropathy, coronary artery disease, stroke, and retinopathy. He...
Source: Cardiovascular and Hematological Agents in Medicinal Chemistry - November 23, 2014 Category: Cardiology Tags: Cardiovasc Hematol Agents Med Chem Source Type: research

Yoga may help protect against heart disease
ConclusionOverall, this review suggests that yoga may be beneficial in reducing risk factors for cardiovascular disease and metabolic syndrome.While these are encouraging findings, the authors also caution that these are based on trials with some limitations, including: There was a wide variation in the type of yoga practised, the frequency and the length of each session across the studies. This means it is difficult to say what the actual effects of each approach are, as the overall effects are just an average across all of these approaches. Some may have more of an effect and some may have less. The review does not rep...
Source: NHS News Feed - December 16, 2014 Category: Consumer Health News Tags: Lifestyle/exercise Heart/lungs Obesity Source Type: news