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Condition: Metabolic Syndrome
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Total 52 results found since Jan 2013.

Increased Stroke Risk in Metabolically Abnormal Normal Weight: a 10-Year Follow-up of 102,037 Participants in China
AbstractThe purpose of this study was to investigate the risks of stroke in subjects with metabolically abnormal normal weight (MANW) in China. We recruited 102,037 participants from the Zhejiang Metabolic Syndrome Cohort and the Kailuan cohort. The mean years of follow-up were 9.9  years. General obesity was defined by body mass index (BMI) ≥ 28, overweight by BMI <  28 and ≥ 24, and normal weight by BMI <  24 and ≥ 18.5. Metabolic abnormality was defined as two or more abnormal components (elevated triglycerides, low high-density lipoprotein cholesterol, elevated systolic blood pressure or di...
Source: Translational Stroke Research - September 6, 2021 Category: Neurology Source Type: research

Elevated Chinese visceral adiposity index increases the risk of stroke in Chinese patients with metabolic syndrome
ConclusionOur findings recommend CVAI as a superior screening tool for detecting MetS and suggest that reducing CVAI can mitigate the risk of stroke in patients with MetS.
Source: Frontiers in Endocrinology - June 29, 2023 Category: Endocrinology Source Type: research

Comparing associations of different metabolic syndrome definitions with ischemic stroke in Chinese elderly population.
CONCLUSION: In this population, Updated ATPIII criteria was a more suitable definition of Mets than definitions of Chinese guide, IDF and JIS for screening high-risk individuals of ischemic stroke, and the additive effects of Mets components might play a greater role than its composition alone in ischemic stroke. PMID: 29092746 [PubMed - as supplied by publisher]
Source: European Journal of Internal Medicine - October 29, 2017 Category: Internal Medicine Authors: Liu Q, Li YX, Hu ZH, Jiang XY, Li SJ, Wang XF Tags: Eur J Intern Med Source Type: research

Concurrency of Early-Age Exposure to Chinese Famine and Diabetes Increases Recurrence of Ischemic Stroke
Conclusions: Concurrency of early-age famine exposure and diabetes mellitus was associated with a higher risk of stroke recurrence within 12 months, and adherence to evidence-based KPI did not reduce the risk significantly.
Source: Frontiers in Neurology - January 20, 2021 Category: Neurology Source Type: research

Association Between Hyperhomocysteinemia Combined with Metabolic Syndrome and Higher Prevalence of Stroke in Chinese Adults Who Have Elevated Blood Pressure
CONCLUSIONS HHcy combined with MS was associated with higher prevalence of stroke in Chinese adults with elevated blood pressure.PMID:35013090 | DOI:10.12659/MSM.934100
Source: Medical Science Monitor - January 11, 2022 Category: Research Authors: Feng Hu Shichao Yu Juan Li Wei Zhou Tao Wang Xiao Huang Huihui Bao Xiaoshu Cheng Source Type: research

TBXAS1 Gene Polymorphism Is Associated with the Risk of Ischemic Stroke of Metabolic Syndrome in a Chinese Han Population
CONCLUSION: These findings suggest that NC_000007.14: g.139985896C>T was related to the incidence of ischemic stroke in the whole and MS population, and individuals who carry the C allele have a reduced risk of ischemic stroke, which may be used as a promising biomarker of disease risk in patients with MS.PMID:35923246 | PMC:PMC9343182 | DOI:10.1155/2022/9717510
Source: Disease Markers - August 4, 2022 Category: Laboratory Medicine Authors: Jie Peng Fanghong Lu Ming Zhong Yingxin Zhao Zhihao Wang Wei Zhang Source Type: research

Identification of Risk Factors for Stroke in China: A Meta-Analysis of Prospective Cohort Studies
This study aimed to identify independent risk factors for first occurrence of stroke in Chinese individuals based on prospective cohort studies. Forty prospective cohort studies assessing 1,984,552 individuals were selected for the final meta-analysis. The identified risk factors for stroke in the Chinese population included old age (RR = 1.86, 95%CI: 1.47–2.36), hypertension (RR = 2.76, 95%CI: 2.26–3.37), cardiovascular disease history (RR = 1.98, 95%CI: 1.06–3.69), chronic kidney disease (RR = 1.65, 95%CI: 1.36–2.01), diabetes mellitus (RR = 1.71, 95%CI: 1.34–2.18), metabolic syndrome (RR = 1.59, 95%CI: 1.33–...
Source: Frontiers in Neurology - March 18, 2022 Category: Neurology Source Type: research

Polymorphism of IL6 receptor gene is associated with ischaemic stroke in patients with metabolic syndrome.
Abstract The interleukin 6 receptor (IL6R) gene has been shown to locate in the chromosome 1q21 associated with metabolic syndrome (MetS), a condition related to the augmented risk of ischaemic stroke (IS), cardiovascular diseases and all-cause mortality. The aim of this study was to assess the relationship between IL6R gene polymorphisms and IS in patients with MetS in the Chinese Han population. We designed a case-control study enrolling 447 patients with MetS plus IS and 438 patients with MetS alone. Tag single nucleotide polymorphisms (SNPs) of the IL6R gene were determined by a fine-mapping strategy and genot...
Source: Brain Research - December 9, 2019 Category: Neurology Authors: Huang X, Ye Q, Zhu Z, Chen W, Chen Y, Li J, Chen S, Xia N, Huang X, Ye Z Tags: Brain Res Source Type: research

Vitamin D and estradiol help guard against heart disease, stroke, and diabetes
(The North American Menopause Society (NAMS)) Vitamin D and estrogen have already shown well-documented results in improving bone health in women. A new study from China suggests that this same combination could help prevent metabolic syndrome, a constellation of conditions that increases the risk of heart disease, stroke, and diabetes in postmenopausal women. Results are published online today in Menopause, the journal of The North American Menopause Society (NAMS).
Source: EurekAlert! - Medicine and Health - June 12, 2019 Category: International Medicine & Public Health Source Type: news

Association of sleep duration with stroke, myocardial infarction, and tumors in a Chinese population with metabolic syndrome: a retrospective study
Previous studies have suggested that abnormal sleep duration is associated with increased risk of metabolic syndrome (MetS). However, evidence on the association of sleep duration with stroke, myocardial infar...
Source: Lipids in Health and Disease - June 27, 2020 Category: Lipidology Authors: Yingnan YE, Linxi ZHANG, Anping WANG, Yuxia Wang, Shiqing WANG, Guang NING and Yiming MU Tags: Research Source Type: research

Metabolic Syndrome Linked to Increased Risk for Stroke Recurrence
THURSDAY, July 29, 2021 -- Metabolic syndrome and some of its components are associated with stroke recurrence, according to a review published online July 28 in Neurology. Fangfang Zhang, M.D., from Xianxiang Central Hospital in China, and...
Source: Drugs.com - Pharma News - July 29, 2021 Category: Pharmaceuticals Source Type: news

Fine-Mapping of the PLCL2 Gene Identifies Candidate Variants Associated With Ischaemic Stroke Risk in Metabolic Syndrome Patients
A genome-wide association study (GWAS) reported PLCL2 on chromosome 3p24. 3 (rs4618210:A>G) as a novel susceptibility locus for myocardial infarction in the Japanese population. As the most common pathological process, atherosclerosis leads to metabolic syndrome (MetS)-related ischaemic stroke (IS) and myocardial infarction. Hypothesizing that polymorphisms of the PLCL2 gene might be associated with the onset and prognosis of IS in MetS patients, we performed the following study in a Chinese Han population. A total of 709 cases (patients with MetS plus IS) and 711 controls (patients with MetS) were enrolled. A fine-mapp...
Source: Frontiers in Neurology - January 20, 2022 Category: Neurology Source Type: research

Fine-Mapping of the < em > PLCL2 < /em > Gene Identifies Candidate Variants Associated With Ischaemic Stroke Risk in Metabolic Syndrome Patients
Front Neurol. 2022 Jan 20;12:743169. doi: 10.3389/fneur.2021.743169. eCollection 2021.ABSTRACTA genome-wide association study (GWAS) reported PLCL2 on chromosome 3p24. 3 (rs4618210:A>G) as a novel susceptibility locus for myocardial infarction in the Japanese population. As the most common pathological process, atherosclerosis leads to metabolic syndrome (MetS)-related ischaemic stroke (IS) and myocardial infarction. Hypothesizing that polymorphisms of the PLCL2 gene might be associated with the onset and prognosis of IS in MetS patients, we performed the following study in a Chinese Han population. A total of 709 cases...
Source: Atherosclerosis - February 7, 2022 Category: Cardiology Authors: Xiaoya Huang Qiang Ye Yanlei Zhang Yanyan Chen Jia Li Jun Sun Zusen Ye Source Type: research

The Association of Arsenic Metabolism with Cancer, Cardiovascular Disease, and Diabetes: A Systematic Review of the Epidemiological Evidence
Conclusions: Population level of iAs% and DMA%, but not MMA%, were associated with arsenic exposure levels. Overall, study findings suggest that higher MMA% was associated with an increased risk of cancer and cardiovascular disease, while lower MMA% was associated with an increased risk of diabetes and metabolic syndrome. Additional population-based studies and experimental studies are needed to further evaluate and understand the role of arsenic exposure in arsenic metabolism and the role of arsenic metabolism in disease development. https://doi.org/10.1289/EHP577 Received: 01 June 2016 Revised: 26 February 2017 Acce...
Source: EHP Research - August 2, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research