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Total 590 results found since Jan 2013.

Outcomes of Treated Hypertension at Age 80 and Older: Cohort Analysis of 79,376 Individuals
ConclusionIn routine primary care, SBP less than 135 mmHg was associated with greater mortality in the oldest adults with hypertension and free of selected potentially confounding comorbidities. Although important confounders were accounted for, observational studies cannot exclude residual confounding. More work is needed to establish whether unplanned SBPs less than 135 mmHg in older adults with hypertension may be a useful clinical sign of poor prognosis, perhaps requiring clinical review of overall care.
Source: Journal of the American Geriatrics Society - December 29, 2016 Category: Geriatrics Authors: Jo ão Delgado, Jane A.H. Masoli, Kirsty Bowman, W. David Strain, George A. Kuchel, Kate Walters, Louise Lafortune, Carol Brayne, David Melzer, Alessandro Ble, Tags: Clinical Investigation Source Type: research

Resting heart rate and the risk of cardiovascular disease, total cancer, and all-cause mortality – a systematic review and dose-response meta-analysis of prospective studies
Conclusion This meta-analysis found an increased risk of coronary heart disease, sudden cardiac death, heart failure, atrial fibrillation, stroke, cardiovascular disease, total cancer and all-cause mortality with greater resting heart rate.
Source: Nutrition, Metabolism and Cardiovascular Diseases - April 22, 2017 Category: Nutrition Source Type: research

Causes of death in atrial fibrillation: Challenges and opportunities
Atrial fibrillation (AF) is an age-related arrhythmia associated with several co-morbidities and significant mortality. Most AF patients are in need of anticoagulation due to increased risk of stroke. Despite anticoagulation, AF patients still have a significant risk of death (about 5% per year). Approximately half of deaths in AF are due to heart-related causes (i.e.: sudden death, heart failure, myocardial infarction), one third of deaths are due to non-vascular causes (i.e.: cancer, respiratory diseases, infections, etc) and the remaining AF patients die from stroke or hemorrhage (about 6% each), or other causes.
Source: Trends in Cardiovascular Medicine - May 10, 2017 Category: Cardiology Authors: Antonio G ómez-Outes, Ma Luisa Suárez-Gea, Jose Manuel García-Pinilla Source Type: research

Plasma stem cell factor levels are associated with risk of cardiovascular disease and death
ConclusionsThis prospective population‐based study demonstrates that subjects with high levels of SCF have a lower risk of cardiovascular events and death. The findings provide clinical support for a protective role of SCF in maintaining cardiovascular integrity.This article is protected by copyright. All rights reserved.
Source: Journal of Internal Medicine - August 26, 2017 Category: Internal Medicine Authors: Harry Bj örkbacka, Ingrid Yao Mattisson, Maria Wigren, Olle Melander, Gunilla Nordin Fredrikson, Eva Bengtsson, Isabel Gonçalves, Peter Almgren, Jens O. Lagerstedt, Marju Orho‐Melander, Gunnar Engström, Jan Nilsson Tags: Original Source Type: research

Cardiorespiratory Fitness and Cardiovascular Disease Prevention: an Update
AbstractPurpose of ReviewCardiovascular diseases account for nearly one third of all deaths globally. Improving exercise capacity and cardiorespiratory fitness (CRF) has been an important target to reduce cardiovascular events. In addition, the American Heart Association defined decreased physical activity as the fourth risk factor for coronary artery disease. Multiple large cohort studies have evaluated the impact of CRF on outcomes. In this review, we will discuss the role of CRF in reducing cardiovascular morbidity and mortality.Recent FindingsRecent data suggest that CRF has an important role in reducing not only cardi...
Source: Current Atherosclerosis Reports - January 16, 2018 Category: Cardiology Source Type: research

Pilates in noncommunicable diseases: A systematic review of its effects.
CONCLUSIONS: Pilates should be considered for patients with NCDs, as it improves exercise tolerance. Future studies with robust methodologies are still needed to clarify its effectiveness on outcomes with moderate, limited or conflicting evidence and to establish the most suitable intervention protocol. PMID: 30012382 [PubMed - in process]
Source: Complementary Therapies in Medicine - July 18, 2018 Category: Complementary Medicine Authors: Miranda S, Marques A Tags: Complement Ther Med Source Type: research

Preventable Heart Problems Killed 415,000 People in 2016. Here ’s How to Keep Your Heart Healthy
Heart problems that were “largely preventable” killed around 415,000 Americans in 2016, new data from the Centers for Disease Control and Prevention (CDC) says, highlighting the importance of proactive interventions. Under its new Million Hearts campaign, which aims to prevent a million heart attacks and strokes by 2022, the CDC looked at 2016 data and identified approximately 2.2 million hospitalizations and 415,000 deaths caused by heart attacks, strokes, heart failure and related conditions that likely could have been avoided. The total number of deaths related to heart issues is even higher — in 2015,...
Source: TIME: Health - September 6, 2018 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized healthytime Heart Disease onetime Source Type: news

Clean air for Brain Heath; ongoing agenda of 2018 World Brain Day
The latest estimate of attributable deaths to pollution worldwide is extraordinary: 9 million deaths annually [2]. Deaths are related to cardiovascular disorders (myocardial infarction, congestive heart failure and stroke), lung diseases and cancers. The recent Global Burden of Disease study, based on 1990 –2013 data from 188 countries demonstrated that air pollution contributes to 29.2% of the global burden of stroke. However the burden varies between 10% in high-income countries and 34% in low- and middle-income countries [3].
Source: Journal of the Neurological Sciences - December 13, 2018 Category: Neurology Authors: J. Reis, P.S. Spencer, M. Wasay, W. Grisold, W.M. Carroll Tags: Letter to the Editor Source Type: research

The association between education and risk of major cardiovascular events among prostate cancer patients: a study from the Diet, Cancer and Health study.
CONCLUSIONS: The risk of acute myocardial infarction was increased in prostate cancer patients with short or medium education compared with long education. Although the educational inequality did not seem to be explained by differences in treatment, lifestyle or cardiovascular risk factors, monitoring of cardiovascular health and health promotion should involve all prostate cancer patients regardless of social position to ensure best prognosis for all. PMID: 30757932 [PubMed - as supplied by publisher]
Source: Acta Oncologica - February 13, 2019 Category: Cancer & Oncology Authors: Moustsen IR, Friberg AS, Larsen SB, Duun-Henriksen AK, Tjønneland A, Kjaer SK, Brasso K, Johansen C, Dalton SO Tags: Acta Oncol Source Type: research

Cardiovascular Programming During and After Diabetic Pregnancy: Role of Placental Dysfunction and IUGR
This study demonstrated that the incidence of ischemic heart disease and death were three times higher among men with low birth weight compared to men with high birth weight (5). Epidemiological investigations of adults born at the time of the Dutch famine between 1944 and 1945 revealed an association between maternal starvation and a low infant birth weight with a high incidence of hypertension and coronary heart disease in these adults (23). Furthermore, Painter et al. reported the incidence of early onset coronary heart disease among persons conceived during the Dutch famine (24). In that regard, Barker's findin...
Source: Frontiers in Endocrinology - April 8, 2019 Category: Endocrinology Source Type: research

Comorbidity in patients with cardiovascular disease in primary care: a cohort study with routine healthcare data.
CONCLUSION: Comorbid conditions are very common in patients with CVD, even in younger age groups. To ensure efficient and effective treatment, organisational adaptations may be required in the healthcare system to accommodate comorbid conditions in patients with CVD. PMID: 31064742 [PubMed - as supplied by publisher]
Source: The British Journal of General Practice - May 6, 2019 Category: Primary Care Authors: Buddeke J, Bots ML, van Dis I, Visseren FL, Hollander M, Schellevis FG, Vaartjes I Tags: Br J Gen Pract Source Type: research

Efficacy and safety of oral anticoagulants in atrial fibrillation patients with cancer —a network meta-analysis
AbstractThere are no guideline recommendations for the use of anticoagulant therapy in atrial fibrillation (AF) patients with cancer, which creates uncertainty about the optimal antithrombotic treatment in these patients. We conducted a network meta-analysis for the first time to assess the efficacy and safety of anticoagulant drugs in patients with AF and concurrent cancer. The PubMed, EMBASE, and Cochrane databases were searched up to March 2019. A search was made for the main anticoagulant drugs (warfarin, dabigatran, apixaban, rivaroxaban, and edoxaban). Outputs were presented as odds ratios (ORs), their corresponding ...
Source: Heart Failure Reviews - August 12, 2019 Category: Cardiology Source Type: research

Cardiovascular, mortality, and kidney outcomes with GLP-1 receptor agonists in patients with type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials
Publication date: Available online 14 August 2019Source: The Lancet Diabetes & EndocrinologyAuthor(s): Søren L Kristensen, Rasmus Rørth, Pardeep S Jhund, Kieran F Docherty, Naveed Sattar, David Preiss, Lars Køber, Mark C Petrie, John J V McMurraySummaryBackgroundGlucagon-like peptide-1 (GLP-1) receptor agonists differ in their structure and duration of action and have been studied in trials of varying sizes and with different patient populations, with inconsistent effects on cardiovascular outcomes reported. We aimed to synthesise the available evidence by doing a systematic review and meta-analysis of cardiovascular ou...
Source: The Lancet Diabetes and Endocrinology - August 15, 2019 Category: Endocrinology Source Type: research

Incidence rates of cardiovascular outcomes in a community ‐based population of cancer patients
ConclusionsIn a population of patients with cancer not exposed to TKIs, cardiovascular risk factors and outcomes are very common, regardless of cancer type. These data can inform the evaluation of potential excess cardiovascular risks from new interventions.
Source: Cancer Medicine - October 29, 2019 Category: Cancer & Oncology Authors: Rajeev Masson, Lina Titievsky, Douglas A. Corley, Wei Zhao, Alfredo R. Lopez, Jennifer Schneider, Jonathan G. Zaroff Tags: ORIGINAL RESEARCH Source Type: research

Efficacy of Aspirin in the Primary Prevention of Cardiovascular Diseases and Cancer in the Elderly: A Population-Based Cohort Study in Korea
ConclusionAspirin reduced the risks of MACCE and cancer without increasing the bleeding risk in elderly Koreans with hypertension, T2DM, or dyslipidemia. Moreover, the benefits of the long-term use of aspirin in reducing the risks of MACCE were demonstrated. However, the decision of using aspirin for primary prevention must be carefully made on an individual basis, while estimating the benefit –risk balance of aspirin.
Source: Drugs and Aging - November 21, 2019 Category: Geriatrics Source Type: research