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Transition of European Cooperative Acute Stroke Study III Results to Clinical Practice: Ninety-Day Outcomes in a US Cohort Brief Reports
Conclusions— For patients treated with intravenous tissue-type plasminogen activator 3 to 4.5 hours from onset in everyday practice in the United States, there is no evidence for increased risk or worse outcomes compared with standard treatment ≤3 hours.
Source: Stroke - November 25, 2013 Category: Neurology Authors: Cronin, C. A., Langenberg, P., Dutta, T. M., Kittner, S. J. Tags: Brief Reports Source Type: research

Risk of Metabolic Syndrome for Stroke Is Not Greater than the Sum of its Components: Thai Epidemiologic Stroke (TES) Study
This study aimed to assess the association of MetS with stroke, and to evaluate whether the risk of MetS is greater than the sum of its components. The Thai Epidemiologic Stroke (TES) study is a community-based cohort study with 19,997 participants, aged 45-80 years, recruited from the general population from 5 regions of Thailand. Baseline survey data were analyzed in cross-sectional analyses. MetS was defined according to criteria from the National Cholesterol Education Program (NCEP) Adult Treatment Panel III, the American Heart Association/National Heart, Lung, and Blood Institute (revised NCEP), and International Diab...
Source: Journal of Stroke and Cerebrovascular Diseases - June 29, 2012 Category: Neurology Authors: Suchat Hanchaiphiboolkul, Nijasri Charnnarong Suwanwela, Niphon Poungvarin, Samart Nidhinandana, Pimchanok Puthkhao, Somchai Towanabut, Tasanee Tantirittisak, Jithanorm Suwantamee, Maiyadhaj Samsen Tags: Original Articles Source Type: research

Plasma free fatty acids and risk of stroke in the Cardiovascular Health Study
ConclusionOur data did not show an association of plasma free fatty acids with incident stroke among community dwelling older adults.
Source: International Journal of Stroke - January 21, 2014 Category: Neurology Authors: Owais Khawaja, Marlena Maziarz, Mary L. Biggs, William T. Longstreth, Joachim H. Ix, Jorge R. Kizer, Susan Zieman, Russell P. Tracy, Dariush Mozaffarian, Kenneth J. Mukamal, David S. Siscovick, Luc Djoussé Tags: Research Source Type: research

Predictors of Stroke Recurrence in Patients with Recent Lacunar Stroke and Response to Interventions According to Risk Status: Secondary Prevention of Small Subcortical Strokes Trial
Conclusions: In this large, carefully followed cohort of patients with recent lacunar stroke and aggressive blood pressure management, prior symptomatic lacunar ischemia, diabetes, black race, and male sex independently predicted ischemic stroke recurrence. The effects of blood pressure targets and dual antiplatelet therapy were similar across the spectrum of independent risk factors and recurrence risk.
Source: Journal of Stroke and Cerebrovascular Diseases - June 24, 2013 Category: Neurology Authors: Robert G. Hart, Lesly A. Pearce, Majid F. Bakheet, Oscar R. Benavente, Robin A. Conwit, Leslie A. McClure, Robert L. Talbert, David C. Anderson Tags: Original Articles Source Type: research

Intravenous Thrombolysis for Acute Ischemic Stroke in the 3- to 4{middle dot}5-Hour Window - The Malabar Experience (P4.224)
CONCLUSIONS: Our initial experience confirms that thrombolysis for ischemic stroke in the extended window is safe and beneficial.Disclosure: Dr. Ummer has nothing to disclose. Dr. Salam has nothing to disclose. Dr. Noone has nothing to disclose. Dr. Kumar has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Ummer, K., Salam, K., Noone, M., Kumar, P. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Stroke Thrombolysis Source Type: research

Localized Retinal Nerve Fiber Layer Defects and Stroke Clinical Sciences
Conclusions— Localized RNFLDs showed a strong association with previous or acute cerebrovascular stroke and vice versa after adjustment for other systemic and ocular factors. Localized RNFLDs that can be assessed by noninvasive optical coherence tomographic imaging may be added to the panoply of retinal morphological features of stroke.
Source: Stroke - May 27, 2014 Category: Neurology Authors: Wang, D., Li, Y., Wang, C., Xu, L., You, Q. S., Wang, Y. X., Zhao, L., Wei, W. B., Zhao, X., Jonas, J. B. Tags: Other diagnostic testing, Other imaging Clinical Sciences Source Type: research

Factors Predicting High Estimated 10-Year Stroke Risk: Thai Epidemiologic Stroke Study
Conclusions: Socioeconomic status, in particular, unemployed/house work and illiterate class, might be good proxy to identify the individuals at higher risk of stroke. The most powerful risk factors were older age, male sex, diabetes mellitus, systolic blood pressure, and current smoking.
Source: Journal of Stroke and Cerebrovascular Diseases - May 1, 2014 Category: Neurology Authors: Suchat Hanchaiphiboolkul, Pimchanok Puthkhao, Somchai Towanabut, Tasanee Tantirittisak, Khwanrat Wangphonphatthanasiri, Thanes Termglinchan, Samart Nidhinandana, Nijasri Charnnarong Suwanwela, Niphon Poungvarin Tags: Original Articles Source Type: research

Different Risk Factor Profiles for Ischemic and Hemorrhagic Stroke in Type 1 Diabetes Mellitus Clinical Sciences
Conclusions— The risk factor profile for ischemic stroke seems partly different from that of hemorrhagic stroke in patients with type 1 diabetes mellitus.
Source: Stroke - August 25, 2014 Category: Neurology Authors: Hagg, S., Thorn, L. M., Forsblom, C. M., Gordin, D., Saraheimo, M., Tolonen, N., Waden, J., Liebkind, R., Putaala, J., Tatlisumak, T., Groop, P.-H., on behalf of the FinnDiane Study Group Tags: Risk Factors, Type 1 diabetes, Acute Cerebral Hemorrhage, Acute Cerebral Infarction Clinical Sciences Source Type: research

Frequency and Determinants of Intracranial Atherosclerotic Stroke in Urban Pakistan
Conclusions: ICAD accounted for one fifth of all strokes making it the most common ischemic stroke mechanism. In addition to aggressive risk factor control, data also indicated broader holistic efforts on ameliorating inequity, unemployment, and stress reduction to reduce stroke because of ICAD.
Source: Journal of Stroke and Cerebrovascular Diseases - August 4, 2014 Category: Neurology Authors: Ayeesha K. Kamal, Asif Rasheed, Khalid Mehmood, Muhammad Murtaza, Moazzam Zaidi, Maria Khan, Nabi Shah, Maria Samuel, Bilal Ahmed, Emmon Raza, Naveeduddin Ahmed, Jamal Ara, Tasnim Ahsan, Syed M. Munir, Shoukat Ali, Karim U. Maki, Muhammad M. Ahmed, Abdul Tags: Original Articles Source Type: research

Plasma Magnesium and Risk of Ischemic Stroke Among Women Clinical Sciences
Conclusions— Lower plasma magnesium levels may contribute to higher risk of ischemic stroke among women.
Source: Stroke - September 22, 2014 Category: Neurology Authors: Akarolo-Anthony, S. N., Jimenez, M. C., Chiuve, S. E., Spiegelman, D., Willett, W. C., Rexrode, K. M. Tags: Acute Cerebral Infarction Clinical Sciences Source Type: research

Long-term disability after lacunar stroke: Secondary prevention of small subcortical strokes
Conclusions: In lacunar stroke patients, older age was associated with worsening long-term disability, even without recurrence. Worse long-term function was associated with diabetes, cognitive status, and prior stroke, and regional differences may be attributable to variations in health care delivery or scale interpretation.
Source: Neurology - March 9, 2015 Category: Neurology Authors: Dhamoon, M. S., McClure, L. A., White, C. L., Lakshminarayan, K., Benavente, O. R., Elkind, M. S. V., On behalf of the SPS3 Investigators Tags: All Cerebrovascular disease/Stroke, All Rehabilitation, All epidemiology ARTICLE Source Type: research

Stroke in Bahrain: rising incidence, multiple risk factors, and suboptimal care
The incidence of stroke in Bahrain is rising in the Bahraini population and has nearly doubled over the last 16 years, while the incidence in the non‐Bahraini population has not changed. Incidence of stroke in the Bahraini population (110/100 000) is now much greater than in the non‐Bahraini population (27/100 000). The Bahraini stroke population is 10 years younger than Western comparators with a much higher prevalence of many of the risk factors for stroke, including diabetes (54%), hypertension (75%) and hyperlipidemia (34%). The combination of an ageing Bahraini population alongside a high prevalence of risk fa...
Source: International Journal of Stroke - April 1, 2015 Category: Neurology Authors: Mona Al Banna, Hassan Baldawi, Ali Kadhim, Hani Humaidan, David L. Whitford Tags: Panorama Source Type: research

Predictors Of Early Mortality And Bad Outcome In Ischemic Stroke (P3.072)
Conclusion: identifying predictors of early mortality or post-stroke disability is mandatory in order to recognize opportunities of improvement and develop strategies for clinical care in this specific subgroup of patients. A multidisciplinary approach is essential to reduce clinical complications and to improve follow up after the hospitalization period.Disclosure: Dr. Luzzi has nothing to disclose. Dr. Zurru has nothing to disclose. Dr. Alonzo has nothing to disclose. Dr. Brescacin has nothing to disclose. Dr. Pigretti has nothing to disclose. Dr. Camera has nothing to disclose. Dr. Colla Machado has nothing to disclose....
Source: Neurology - April 8, 2015 Category: Neurology Authors: Luzzi, A., Zurru, M., Alonzo, C., Brescacin, L., Pigretti, S., Camera, L., Colla Machado, P., Waisman, G., Cristiano, E. Tags: Cerebrovascular Disease and Interventional Neurology: Ischemic Stroke Outcome Source Type: research

Weather as physiologically equivalent was not associated with ischemic stroke onsets in Vienna, 2004-2010.
Abstract Stroke rates were found to have seasonal variations. However, previous studies using air temperature, humidity, or air pressure separately were not adequate, and the study catchment was not clearly drawn. Therefore, here we proposed to use a thermal index called physiologically equivalent temperature (PET) that incorporates air temperature, humidity, wind speed, cloud cover, air pressure and radiation flux from a biometeorological approach to estimate the effect of weather as physiologically equivalent on ischemic stroke onsets in an Austrian population. Eight thousand four hundred eleven stroke events in...
Source: Environmental Science and Pollution Research International - April 16, 2015 Category: Environmental Health Authors: Ferrari J, Shiue I, Seyfang L, Matzarakis A, Lang W, Austrian Stroke Registry Collaborators Tags: Environ Sci Pollut Res Int Source Type: research

Stroke risk stratification in acute dizziness presentations: A prospective imaging-based study
Conclusion: In acute dizziness presentations, the combination of ABCD2 score, general neurologic examination, and a specialized OM examination has the capacity to risk-stratify acute stroke on MRI.
Source: Neurology - November 23, 2015 Category: Neurology Authors: Kerber, K. A., Meurer, W. J., Brown, D. L., Burke, J. F., Hofer, T. P., Tsodikov, A., Hoeffner, E. G., Fendrick, A. M., Adelman, E. E., Morgenstern, L. B. Tags: All Health Services Research, Decision analysis, All Cerebrovascular disease/Stroke, All Neurotology, Vertigo ARTICLE Source Type: research