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Studying Effects of Weather Parameters on Acute Stroke: Considering the Contribution of “Risk Factors” and “Triggering Factors” Together
A recently published article in the Journal of Stroke and Cerebrovascular Diseases regarding the effect of season and atmospheric temperature variation in acute stroke by Gomes et al has drawn our attention. The authors studied the variation in the incidence of stroke hospitalizations across seasons and with short-term temperature change in a tropical setting by examining 651 consecutive stroke events occurred during the period of August 1, 2005, through July 31, 2006. The study illustrated that sudden declines in the minimum temperature over the 5-10 days before the event were associated with a 20%-30% higher incidence...
Source: Journal of Stroke and Cerebrovascular Diseases - August 21, 2013 Category: Neurology Authors: Mohammad Al Mamun, Nahid Rumana, Adrian V. Specogna, Tanvir C. Turin Tags: Letters to the Editor Source Type: research

Investigation of Vaspin Level in Patients with Acute Ischemic Stroke
This study was intended to investigate the relation between vaspin and stroke and stroke and other risk factors.Methods: A total of 50 patients with stroke, as 28 men (56%) and 22 women (44%), and a total of 50 healthy individuals, as 25 men (50%) and 25 women (50%), were enrolled in the study. Blood samples were taken in the acute period (first 48 hours) in the patient group, and serum vaspin levels were measured. Vaspin level was also measured in the control group. The association of vaspin with the lipid parameters, gender, and the severity of internal carotid artery (ICA) stenosis in the patient group was evaluated. S...
Source: Journal of Stroke and Cerebrovascular Diseases - April 16, 2013 Category: Neurology Authors: Hasan S. Cura, Hasan H. Özdemir, Caner F. Demir, Serpil Bulut, Nevin İlhan, Mehmet Fatih Inci Tags: Original Articles Source Type: research

Leukoaraiosis Is Associated With Impaired Functional Recovery And Outcome After Mild Ischemic Stroke. (P7.153)
CONCLUSIONS: Leukoaraiosis is an independent risk factor for poor functional outcome at discharge after minor ischemic stroke. Further analysis whether this effect persists to 90 days are ongoing.Disclosure: Dr. Onteddu has nothing to disclose. Dr. Minaeian has nothing to disclose. Dr. Goddeau has nothing to disclose. Dr. Henninger has received personal compensation for activities with Brainsgate as a consultant.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Onteddu, S., Minaeian, A., Goddeau, R., Henninger, N. Tags: Cerebrovascular Disease and Interventional Neurology: Predictors of Outcome After Ischemic Stroke Source Type: research

Brain Natriuretic Peptide in Acute Ischemic Stroke
Elevated serum brain natriuretic peptide (BNP) levels are associated with cardioembolic stroke mainly because of atrial fibrillation (AF). However, the mechanisms of increased serum BNP levels are hitherto unclear. We aimed to identify the factors associated with increased BNP levels in patients with acute ischemic stroke. We measured serum BNP levels in consecutive patients aged 18 years or older. Stroke subtypes were classified using the Trial of ORG 10172 in Acute Stroke Treatment criteria. Categorical variables included age, sex, smoking status, alcohol consumption status, hypertension, diabetes mellitus, dyslipidemia...
Source: Journal of Stroke and Cerebrovascular Diseases - October 10, 2013 Category: Neurology Authors: Kenji Maruyama, Tsuyoshi Shiga, Mutsumi Iijima, Saori Moriya, Satoko Mizuno, Sono Toi, Kotaro Arai, Kyomi Ashihara, Kayoko Abe, Shinichiro Uchiyama Tags: Original Articles Source Type: research

Quality of Life after Lacunar Stroke: The Secondary Prevention of Small Subcortical Strokes Study
Background: We sought to describe the course and predictors of quality of life (QOL) after lacunar stroke. We hypothesized that there is a decline in QOL after recovery from lacunar stroke.Methods: The Secondary Prevention of Small Subcortical Strokes is a clinical trial in lacunar stroke patients with annual assessments of QOL with the stroke-specific QOL score. The overall score was used and analyzed as a continuous variable (range 0-5). We fit linear mixed models to assess the trend in QOL over time, assuming linearity of time, and adjusted for demographics, medical risk factors, cognitive factors, and functional status...
Source: Journal of Stroke and Cerebrovascular Diseases - October 30, 2013 Category: Neurology Authors: Mandip S. Dhamoon, Leslie A. McClure, Carole L. White, Helena Lau, Oscar Benavente, Mitchell S.V. Elkind Tags: Original Articles Source Type: research

Occurrence and Predictors of Persistent Impaired Glucose Tolerance After Acute Ischemic Stroke or Transient Ischemic Attack
Conclusions: Half of the patients with impaired glucose tolerance after a TIA or ischemic stroke have persistent impaired glucose tolerance. We provide a prediction model to identify patients at risk of persistent impaired glucose tolerance, with statin use, triglyceride, and fasting plasma glucose as the most important predictors, which after external validation might be used to optimize secondary prevention.
Source: Journal of Stroke and Cerebrovascular Diseases - April 10, 2014 Category: Neurology Authors: Susanne Fonville, Heleen M. den Hertog, Adrienne A.M. Zandbergen, Peter J. Koudstaal, Hester F. Lingsma Tags: Original Articles Source Type: research

Abstract 10: Predictors of Poor Outcome in Acute Ischemic Stroke Patients after Successful Recanalization Session Title: Concurrent I Session B: Oral Abstracts on Stroke Topics
Conclusions: Age, occlusion site, high NIHSS, diabetes, not receiving IV t-PA, use of rescue therapy and three or more passes, were associated with poor 90-day outcome despite successful recanalization.
Source: Circulation: Cardiovascular Quality and Outcomes - June 2, 2014 Category: Cardiology Authors: Starosciak, A. K., Linfante, I., Walker, G., Zaidat, O. O., Castonguay, A. C., Lin, E., Dabus, G., NASA Investigators Tags: Session Title: Concurrent I Session B: Oral Abstracts on Stroke Topics Source Type: research

Increased risk of stroke in patients with chronic kidney disease after recurrent hypoglycemia
Conclusions: CKD was associated with a higher risk of stroke and mortality in patients with hypoglycemia. Recurrent hypoglycemia considerably increased the risk of stroke and overall mortality in patients with CKD regardless of whether they had diabetes. These results suggest that hypoglycemia has a crucial role in stroke and death in patients with CKD.
Source: Neurology - August 18, 2014 Category: Neurology Authors: Yu, T.-M., Lin, C.-L., Chang, S.-N., Sung, F.-C., Kao, C.-H. Tags: Prognosis, All Cerebrovascular disease/Stroke, Cohort studies ARTICLE Source Type: research

Copeptin for the Prediction of Recurrent Cerebrovascular Events After Transient Ischemic Attack: Results From the CoRisk Study Clinical Sciences
Conclusions— Copeptin improved the prognostic value of the ABCD2 score for the prediction of stroke but not TIA, and it may help clinicians in refining risk stratification for patients with TIA. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00878813.
Source: Stroke - September 22, 2014 Category: Neurology Authors: De Marchis, G. M., Weck, A., Audebert, H., Benik, S., Foerch, C., Buhl, D., Schuetz, P., Jung, S., Seiler, M., Morgenthaler, N. G., Mattle, H. P., Mueller, B., Christ-Crain, M., Arnold, M., Katan, M. Tags: Acute Cerebral Infarction, Emergency treatment of Stroke Clinical Sciences Source Type: research

Anemia on admission predicts short‐ and long‐term outcomes in patients with acute ischemic stroke
ConclusionAnemia is common among AIS patients and is associated with cardiovascular comorbidities. Low hemoglobin status independently predicts short and long‐term mortality.
Source: International Journal of Stroke - November 27, 2014 Category: Neurology Authors: Haralampos Milionis, Vasileios Papavasileiou, Ashraf Eskandari, Suzette D'Ambrogio‐Remillard, George Ntaios, Patrik Michel Tags: Research Source Type: research

Persistent Cerebrovascular Damage After Stroke in Type Two Diabetic Rats Measured by Magnetic Resonance Imaging Basic Sciences
Conclusions— Using MRI, T2-weighted imaging did not detect significant differences of the ischemic lesion volumes between T2DM and WT rats. In contrast to the WT rats, however, contrast-enhanced T1-weighted imaging and susceptibility-weighted imaging identified much more severe ischemic vascular damage, whereas fractional anisotropy demonstrated lower axonal density in the T2DM rats after stroke.
Source: Stroke - January 26, 2015 Category: Neurology Authors: Ding, G., Yan, T., Chen, J., Chopp, M., Li, L., Li, Q., Cui, C., Ning, R., Jiang, Q. Tags: Type 2 diabetes Basic Sciences Source Type: research

Rates of Ischemic Stroke During Warfarin Treatment for Atrial Fibrillation Brief Reports
Conclusions— In a large cohort of older patients with atrial fibrillation, we observed the highest rate of ischemic stroke in the first 30 days after warfarin initiation. Although causation cannot be established given the observational nature of this study, our findings highlight the need for future research in this population.
Source: Stroke - March 23, 2015 Category: Neurology Authors: Tung, J. M., Mamdani, M. M., Juurlink, D. N., Paterson, J. M., Kapral, M. K., Gomes, T. Tags: Cardiovascular Pharmacology, Anticoagulants, Epidemiology Brief Reports Source Type: research

Effect of Cigarette Smoking on Outcomes of Acute Ischemic Stroke Treated with Intravenous Thrombolysis: Is There Any Paradox in The Brain? (P3.071)
Conclusion: There is no smoker's paradox in ischemic stroke.Disclosure: Dr. Hussein has nothing to disclose. Dr. Niemann has nothing to disclose. Dr. Stuck has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Hussein, H., Niemann, N., Stuck, L., Qureshi, A. Tags: Cerebrovascular Disease and Interventional Neurology: Ischemic Stroke Outcome Source Type: research

Racial differences in the Risk factors, Severity, Outcomes and Treatment in Acute Ischemic Stroke (P7.141)
Conclusion: Despite great disparity in both groups the outcomes were similar.Disclosure: Dr. Chauhan has nothing to disclose. Dr. Ali has nothing to disclose. Dr. Bianchi has nothing to disclose. Dr. Hinduja has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Chauhan, M. A., Ali, S., Bianchi, N., Hinduja, A. Tags: Cerebrovascular Disease and Interventional Neurology: Race, Ethnicity, and Stroke Source Type: research

Insular Cortex Lesions, Cardiac Troponin, and Detection of Previously Unknown Atrial Fibrillation in Acute Ischemic Stroke: Insights From the Troponin Elevation in Acute Ischemic Stroke Study Clinical Sciences
Conclusions— Insular cortex involvement, higher admission high-sensitivity cardiac troponin T, older age, hypertension, and longer monitoring are associated with new detection of AF during in-hospital ECG monitoring. Patients with higher high-sensitivity cardiac troponin T or insular cortex involvement may be candidates for prolonged ECG monitoring.
Source: Stroke - April 27, 2015 Category: Neurology Authors: Scheitz, J. F., Erdur, H., Haeusler, K. G., Audebert, H. J., Roser, M., Laufs, U., Endres, M., Nolte, C. H. Tags: Acute Cerebral Infarction Clinical Sciences Source Type: research