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Condition: Hypertension
Nutrition: Vitamins

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Total 319 results found since Jan 2013.

Dabigatran and vitamin K antagonists ’ use in naïve patients with non-valvular atrial fibrillation: a cross-sectional study of primary care-based electronic health records
ConclusionsMost patients recently diagnosed with non-valvular atrial fibrillation initiated treatment with VKA. Primary healthcare patients with non-valvular atrial fibrillation initiating dabigatran are younger, had a lower risk of stroke or bleeding, fewer comorbidity and more history of stroke and intracranial haemorrhage compared to those who were initiated on VKA.
Source: European Journal of Clinical Pharmacology - July 19, 2017 Category: Drugs & Pharmacology Source Type: research

Shifting to a non-vitamin K antagonist oral anticoagulation agent from vitamin K antagonist in atrial fibrillation
ConclusionIn a contemporary setting among VKA-experienced NVAF patients; VKA is still prevalent although about 30% by December 2015 had shifted to a NOAC.
Source: Europace - June 28, 2017 Category: Cardiology Source Type: research

Sun exposure influences the prognostic power of components of mineral metabolism in patients with coronary artery disease
Conclusions In patients with stable CAD, low calcidiol and high FGF-23 plasma levels predict an adverse prognosis only when the sample is obtained during the months with LSE. SE should be taken into account in the clinical practice.
Source: Nutrition, Metabolism and Cardiovascular Diseases - June 16, 2017 Category: Nutrition Source Type: research

Drinking Water Salinity and Raised Blood Pressure: Evidence from a Cohort Study in Coastal Bangladesh
Conclusions: DWS is an important source of daily sodium intake in salinity-affected areas and is a risk factor for hypertension. Considering the likely increasing trend in coastal salinity, prompt action is required. Because MAR showed variable effects, alternative technologies for providing reliable, safe, low-sodium fresh water should be developed alongside improvements in MAR and evaluated in “real-life” salinity-affected settings. https://doi.org/10.1289/EHP659 Received: 01 February 2016 Revised: 14 June 2016 Accepted: 31 August 2016 Published: 30 May 2017 Address correspondence to Dr. Pauline Scheelbeek, ...
Source: EHP Research - May 30, 2017 Category: Environmental Health Authors: Web Admin Tags: Research Source Type: research

Meta-analysis of folic acid efficacy trials in stroke prevention: Insight into effect modifiers
Conclusions: Folic acid supplementation could reduce the stroke risk in regions without folic acid fortification, particularly in trials using a relatively low dosage of folic acid and with low vitamin B12 levels.
Source: Neurology - May 8, 2017 Category: Neurology Authors: Zhao, M., Wu, G., Li, Y., Wang, X., Hou, F. F., Xu, X., Qin, X., Cai, Y. Tags: Stroke prevention, All Cerebrovascular disease/Stroke, Clinical trials Randomized controlled (CONSORT agreement), All epidemiology ARTICLE Source Type: research

Factors associated with non –vitamin K antagonist oral anticoagulants for stroke prevention in patients with new-onset atrial fibrillation: Results from the Outcomes Registry for Better Informed Treatment of Atrial Fibrillation II (ORBIT-AF II)
Conclusions In contemporary clinical practice, up to three-fourths of patients with new-onset AF are now initially treated with a NOAC for stroke prevention. Those selected for NOAC treatment had lower stroke and bleeding risk profiles, were more likely treated by cardiologists, and had higher socioeconomic status. Trial registration clinicaltrials.gov Identifier: NCT01701817
Source: American Heart Journal - April 25, 2017 Category: Cardiology Source Type: research

Blood pressure control in anticoagulated patients with hypertension and atrial fibrillation.
CONCLUSIONS: More than 75% of hypertensive patients with AF achieved BP goals, and this rate was higher in elderly. More than 2 thirds of patients were on combined therapy. BP control appears to be better in AF patients than in general hypertensive population. PMID: 28385080 [PubMed - as supplied by publisher]
Source: Blood Pressure - April 8, 2017 Category: Hematology Tags: Blood Press Source Type: research

New oral anticoagulants and prevention of thromboembolic events in patients with hypertension and atrial fibrillation: an appraisal
Arterial hypertension (HTN) and atrial fibrillation often coexist and the combination of these two conditions carries an increased risk of stroke. HTN is one of the most important risk factors included in the scores for stoke prediction in atrial fibrillation used to assess the need of anticoagulation, and HTN has also been strictly related to bleeding complications of antithrombotic therapy. Antithrombotic drugs options include vitamin K antagonists, or new oral anticoagulants, recently approved for stroke prevention in nonvalvular atrial fibrillation. More favorable new oral anticoagulant efficacy and safety, compared wi...
Source: Journal of Hypertension - March 2, 2017 Category: Cardiology Tags: Reviews Source Type: research

Vitamin D and Urinary Incontinence among Korean Women: a Propensity Score-matched Analysis from the 2008-2009 Korean National Health and Nutrition Examination Survey.
In conclusion, low serum vitamin D is not significantly and independently related to female UI after propensity score matching in representative Korean data. PMID: 28244294 [PubMed - in process]
Source: Journal of Korean Medical Science - March 2, 2017 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

Effects of noise on vascular function, oxidative stress, and inflammation: mechanistic insight from studies in mice
ConclusionWe established a novel and unique aircraft noise stress model with increased blood pressure and vascular dysfunction associated with oxidative stress. This animal model enables future studies of molecular mechanisms, mitigation strategies, and pharmacological interventions to protect from noise-induced vascular damage.
Source: European Heart Journal - February 17, 2017 Category: Cardiology Source Type: research

Cerebral Amyloid Angiopathy in Stroke Medicine.
CONCLUSION: In patients with CAA, arterial hypertension should be tightly controlled. On the other hand, caution should be exercised in prescribing oral anticoagulants or platelet aggregation inhibitors for patients with CAA, or statins for patients who have already sustained a lobar ICH. PMID: 28179050 [PubMed - in process]
Source: Deutsches Arzteblatt International - February 11, 2017 Category: Journals (General) Tags: Dtsch Arztebl Int Source Type: research

Making Sense of Nutraceuticals in China
The Chinese nutraceutical market is considered the third largest in the world after the US and Japan, or the fourth largest if Europe is counted as a single market.Despite strong fundamentals and high rates of annual growth, though, the Chinese market remains some way from realizing its true potential. Its evolution is muddied by ambiguities around what nutraceuticals actually are and how they should be managed.The result has been polarization between over-zealous regulation of so-called health foods, and a grey market where products have skirted approval procedures through questionable positioning or by exploiting alterna...
Source: EyeForPharma - February 10, 2017 Category: Pharmaceuticals Authors: Marc Yates Source Type: news

Nutraceuticals and dietary supplements to improve quality of life and outcomes in heart failure patients.
CONCLUSIONS: Evidence suggests that the supplementation with nutraceuticals may be a useful option for effective management of HF, with the advantage of excellent clinical tolerance. PMID: 28120718 [PubMed - as supplied by publisher]
Source: Current Pharmaceutical Design - January 23, 2017 Category: Drugs & Pharmacology Authors: Cicero AF, Colletti A Tags: Curr Pharm Des Source Type: research

Rational medical therapy is the key to effective cardiovascular disease prevention
Publication date: Available online 19 January 2017 Source:Canadian Journal of Cardiology Author(s): J. David Spence In an era in which personalized medicine based on genotyping is being proposed, it is timely to recognize that existing therapies could be markedly improved if based on available phenotyping. Blood pressure control, which is poor on a worldwide basis, is a major opportunity to reduce cardiovascular risk. There are many genetic variants that have a small effect on blood pressure, but specific therapies are not available for most of them. Individualized therapy for hypertension using plasma renin and aldostero...
Source: Canadian Journal of Cardiology - January 18, 2017 Category: Cardiology Source Type: research

Influence of vitamin D levels on the treatment of premature ventricular complexes in patients with chronic kidney disease
Conclusions We suggest that the effectiveness of β-blocker treatment for PVCs in CKD patients was observed in all 25(OH)D levels. However, the responsiveness was higher in patients with a normal range of 25(OH)D in comparison to patients with deficiency or insufficiency in 25(OH)D levels. Whether vitamin D supplementation increases the efficacy of beta-blocker mediated suppression of PVCs requires further evaluation.
Source: IJC Metabolic and Endocrine - January 6, 2017 Category: Endocrinology Source Type: research