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Total 22 results found since Jan 2013.
Association of 24 h Blood Pressure on Functional Outcome in Patients with Acute Ischemic Stroke Post Intravenous Thrombolysis
Conclusion: An elevated mean SBP and greater SBP variability were predictive of poor functional outcomes, whereas a high SBP variability predicted sICH. Our study emphasizes the need for BP control and minimizing large fluctuations to achieve good poststroke outcomes.Cerebrovasc Dis
Source: Cerebrovascular Diseases - November 24, 2022 Category: Neurology Source Type: research
Primary Prevention of Ischemic Stroke
This article provides an overview on conventional modifiable risk factors for ischemic stroke and highlights the emerging risk factors and approaches for high-risk group identification and treatment. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents | Abstract | Full text
Source: Seminars in Neurology - November 17, 2022 Category: Neurology Authors: Sabayan, Behnam Tags: Review Article Source Type: research
COVID-19 and Stroke Trends in A Tertiary Care Center from South India -Our Monsoon Experience
Conclusion: Our study was a hypothesis-generating study with a limited number of patients. This study has reconfirmed the higher severity of the stroke, with a higher mRS score and mortality during the pandemic, especially among COVID-19-positive stroke patients.
Source: Neurology India - October 21, 2022 Category: Neurology Authors: Dileep Ramachandran Githin Benoy George Praveen Panicker R Aravind MK Suresh Thomas Iype Source Type: research
Influencing factors of stroke occurrence and recurrence in hypertensive patients: A prospective follow ‐up studies
ConclusionsFor people with high blood pressure, it is necessary to exercise properly, control body weight, avoid obesity, quit smoking, reduce alcohol consumption, and reasonably control blood pressure, blood sugar, and blood lipid.
Source: Brain and Behavior - September 13, 2022 Category: Neurology Authors: Yuelong Jin,
Minmin Jiang,
Na Pan,
Yan Chen,
Weiwei Chang,
Lijun Zhu,
Zhengmei Fang,
Shizao Fei,
Zixuan Zhou,
Siyun Zhou,
Lianping He,
Yingshui Yao Tags: ORIGINAL ARTICLE Source Type: research
Neuroprotective and Proneurogenic Effects of Glucosamine in an Internal Carotid Artery Occlusion Model of Ischemia
AbstractNeuroprotective, antineuroinflammatory, and proneurogenic effects of glucosamine, a naturally occurring amino sugar, have been reported in various animal models of brain injury including cerebral ischemia and hypoxic brain damage. Given that clinical translation of therapeutic candidates identified in animal models of ischemic stroke has remained unsatisfactory in general, possibly due to inadequacy of existing models, we sought to study the effects of glucosamine in a recently developed, clinical condition mimicking mouse model of internal cerebral artery occlusion. In this model of mild to moderate striatal damag...
Source: NeuroMolecular Medicine - November 27, 2021 Category: Neurology Source Type: research
High serum complement component C4 as a unique predictor of unfavorable outcomes in diabetic stroke
In this study, the association of serum complement levels with the prognosis of diabetic stroke was examined. Patients with acute ischemic stroke were recruited and were divided into two groups according to their history of diabetes. Baseline data on the admission, including C3 and C4 were collected. Neurologic function at discharge was the primary outcome and was quantified by the National Institutes of Health Stroke Scale (NIHSS). A total of 426 patients with acute ischemic stroke (116 diabetic strokes and 310 non-diabetic strokes) were recruited in this study. There were significant differences between the two groups in...
Source: Metabolic Brain Disease - September 4, 2021 Category: Neurology Source Type: research
Causes of mortality in patients after first ‐ever stroke: A retrospective population‐based study
ConclusionThere are no sex differences in mortality after first-ever stroke. Elderly patients need more support and attention due to greater stroke mortality. Complete blood count, lipid profile and blood levels of urea, creatinine, and fasting blood sugar may be useful in predicting mortality after first-ever stroke.
Source: Brain and Behavior - September 2, 2021 Category: Neurology Authors: Arash Mosarrezaii,
Mohammad Reza Amiri ‐Nikpour,
Sina Dindarian,
Samerand Rahimzadeh,
Sedra Mohammadi,
Hozan Mohammadi Tags: ORIGINAL RESEARCH Source Type: research
Modified Renshen Yangrong decoction enhances angiogenesis in ischemic stroke through promotion of MicroRNA ‐210 expression by regulating the HIF/VEGF/Notch signaling pathway
ConclusionGSYRD promotes cerebral protection following angiogenesis and ischemic brain injury. The specific mechanism was activating the HIF/VEGF/Notch signaling pathway via miRNA-210.
Source: Brain and Behavior - August 1, 2021 Category: Neurology Authors: Ce Liang,
Teng Zhang,
Xu ‐Liang Shi,
Lin Jia,
Ya‐Li Wang,
Cui‐Huan Yan Tags: ORIGINAL RESEARCH Source Type: research
Molecular profile of the rat peri-infarct region four days after stroke: Study with MANF.
In this study, we examine the molecular profile of the peri-infarct region on post-stroke day four, time when reparative processes are ongoing. We used a multiomics approach, involving RNA sequencing, and mass spectrometry-based proteomics and metabolomics to characterize molecular changes in the peri-infarct region. We also took advantage of our previously developed method to express transgenes in the peri-infarct region where self-complementary adeno-associated virus (AAV) vectors were injected into the brain parenchyma on post-stroke day 2. We have previously used this method to show that mesencephalic astrocyte-derived...
Source: Experimental Neurology - March 26, 2020 Category: Neurology Authors: Teppo J, Vaikkinen A, Stratoulias V, Mätlik K, Anttila JE, Smolander OP, Pöhö P, Harvey BK, Kostiainen R, Airavaara M Tags: Exp Neurol Source Type: research
Intravenous thrombolysis with tPA and cortical involvement increase the risk of early poststroke seizures: Results of a case–control study
This article is part of the Special Issue “Seizures & Stroke
Source: Epilepsy and Behavior - June 8, 2019 Category: Neurology Source Type: research
Intravenous thrombolysis with tPA and cortical involvement increase the risk of early poststroke seizures: Results of a case-control study.
This article is part of the Special Issue "Seizures & Stroke.
PMID: 31182396 [PubMed - as supplied by publisher]
Source: Epilepsy and Behaviour - June 6, 2019 Category: Neurology Authors: Brigo F, Schneider M, Wagenpfeil G, Ragoschke-Schumm A, Fousse M, Holzhoffer C, Nardone R, Faßbender K, Lochner P Tags: Epilepsy Behav Source Type: research
Cell-Based Therapies for Stroke: Promising Solution or Dead End? Mesenchymal Stem Cells and Comorbidities in Preclinical Stroke Research
Conclusion
The high prevalence of comorbidities in patients with stroke indicates the need for therapies in preclinical studies that take into account these comorbidities in order to avoid failures in translation to the patient. Preclinical studies are beginning to evaluate the efficacy of MSC treatment in stroke associated with comorbidities, especially hypertension, for ischemic and hemorrhagic stroke. Regarding aging and diabetes, only ischemic stroke studies have been performed. For the moment, few studies have been performed and contradictory results are being reported. These contradictory results may be due to the u...
Source: Frontiers in Neurology - April 8, 2019 Category: Neurology Source Type: research
Predictors of intracerebral hemorrhage in acute stroke patients receiving intravenous recombinant tissue plasminogen activator
Conclusion: High NIHSS score, increased stroke onset to thrombolysis time , high blood sugar at presentation ,prior diabetes and hypertension increase the chances of sICH. None of these contraindicate thrombolysing strokes but should caution the physician.
Source: Annals of Indian Academy of Neurology - September 4, 2018 Category: Neurology Authors: Vijay Chenna Subhash Kaul Swetha Tandra Sireesha Yareeda Neeharika Mathukumalli Abhijeet Kumar Kohat Rukmini Mridula Kandadai Suryaprabha Turaga Jabeen Afshan Sheik AK Meena Rupam Borgohain Source Type: research
