Intravenous thrombolysis with tPA and cortical involvement increase the risk of early poststroke seizures: Results of a case–control study

This article is part of the Special Issue “Seizures &Stroke
Source: Epilepsy and Behavior - Category: Neurology Source Type: research

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AbstractThis is a letter to the Editor concerning the recently published article by Zerem et al. The paper described a 12yo female with multisystem mitochondrial disorder (MID) due to the compound heterozygous variants c.1963_1964dupAT and p.Ile382Met inOPA1 manifesting phenotypically with congenital nystagmus, developmental delay, visual impairment, gait ataxia, epilepsy, a stroke-like episode (SLE) with encephalopathy and vomiting, and hearing impairment. This interesting case could be more meaningful by providing more information about the treatment of the SLE/stroke-like lesion (SLL), about the morphological characteri...
Source: Metabolic Brain Disease - Category: Neurology Source Type: research
In conclusion, these results indicated that SXD produced beneficial sedative and hypnotic bioactivities mediated by regulating the serotonergic and immune system.
Source: Metabolic Brain Disease - Category: Neurology Source Type: research
High blood pressure: A common diagnosis, that shows hardly any symptoms, but can be deadly. Hardened arteries and blood forced too hard against artery walls can lead to a heart attack or stroke. Fortunately, there are lifestyle improvements that can lower blood pressure and potentially save your life.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Abbott Laboratories has been wildly successful with its FreeStyle Libre continuous glucose monitor (CGM) since winning FDA approval in 2017, but it seems some investors and patients may be getting restless as the U.S. market waits for the second-generation of the blockbuster technology. We first noted some signs of impatience for Libre 2 in our coverage of Abbott's third-quarter earnings call in October. One reader commented on that article that "I don’t particularly care about investors becoming impatient, as a Freestyle Libre user I am growing impatie...
Source: MDDI - Category: Medical Devices Authors: Tags: Business Source Type: news
ConclusionsThese findings suggest that MXYF inhibits autophagy after OGD/R-induced PC12 cell injury through the AMPK-mTOR pathway. Thus, MXYF might have therapeutic potential in treating ischemic stroke.Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
ConclusionLig exerts renoprotective functions in an animal model of DN mediated by antioxidant action, inhibition of apoptosis, anti-inflammatory action, reduction of renal fibrosis, reduction of the proliferation of mesangial cells, inhibition of endotheliosis, inhibition of atherosclerosis and promotion of renal autophagy. The positive conclusion should be treated cautiously because of various methodological flaws. Further studies are recommended according to ARRIVE guidelines. The method of modeling with high-dose STZ should be avoided and improved STZ modeling schemes are recommended. Considering the large dosage range...
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
TYPE 2 diabetes is a chronic condition that may require you to forgo your favourite treats to stave off the risks posed by rising blood sugar levels. Certain foods may seem healthy on the surface but contain hidden risks that can send blood sugar soaring, including a popular breakfast item.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
No abstract available
Source: Neurology Today - Category: Neurology Tags: For Your Patients Source Type: research
Publication date: June 2020Source: Materials Today Communications, Volume 23Author(s): S N Madhuri, M V Murugendrappa, K RukmaniAbstractConcentration dependent dielectric and electrical properties of PVA-Gd2O3 nanocomposite films over a wide range of frequencies (100Hz-1 MHz) and temperatures (303 K–423 K) is reported here. TEM of the Gd2O3 nanoparticles showed that they could be indexed to the cubic phase. The frequency variation of the dielectric permittivity and dielectric loss could be explained by the Maxwell Wagner Sillar’s model. The dielectric permittivity decreased in the composite films contrary to ob...
Source: Materials Today Communications - Category: Materials Science Source Type: research
In conclusion, our kindling model demonstrates the ability of insular cortex stimulation to generate epilepsy. Our model thus offers a practical tool for studies of the role of the insular cortex in sudden unexpected death in epilepsy.
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
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