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Nutrition: Calcium

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Total 1249 results found since Jan 2013.

Relevance of stromal interaction molecule 1 (STIM1) in experimental and human stroke
Pflugers Arch. 2021 Nov 10. doi: 10.1007/s00424-021-02636-w. Online ahead of print.ABSTRACTStroke represents a main cause of death and permanent disability worldwide. In the attempt to develop targeted preventive and therapeutic strategies, several efforts were performed over the last decades to identify the specific molecular abnormalities preceding cerebral ischemia and neuronal death. In this regard, mitochondrial dysfunction, autophagy, and intracellular calcium homeostasis appear important contributors to stroke development, as underscored by recent pre-clinical evidence. Intracellular calcium (Ca2+) homeostasis is re...
Source: Pflugers Archiv : European Journal of Physiology - November 10, 2021 Category: Physiology Authors: Rosita Stanzione Maurizio Forte Maria Cotugno Franca Bianchi Simona Marchitti Speranza Rubattu Source Type: research

Association of DNA Methylation Patterns in 7 Novel Genes With Ischemic Stroke in the Northern Chinese Population
Conclusion: Our results demonstrate that DNA methylation plays a crucial part in ischemic stroke. The methylation of these 7 genes may be potential diagnostic biomarker for ischemic stroke.PMID:35480311 | PMC:PMC9035884 | DOI:10.3389/fgene.2022.844141
Source: Atherosclerosis - April 28, 2022 Category: Cardiology Authors: Hongwei Sun Jia Xu Bifeng Hu Yue Liu Yun Zhai Yanyan Sun Hongwei Sun Fang Li Jiamin Wang Anqi Feng Ying Tang Jingbo Zhao Source Type: research

Vitamin D supplementation and risk of stroke: A meta-analysis of randomized controlled trials
ConclusionOur study revealed that additional vitamin D supplementation did not reduce the risk of stroke. Therefore, additional RCTs of similar design should not be encouraged to assess any association between vitamin D supplementation and reduced stroke risk.
Source: Frontiers in Neurology - August 18, 2022 Category: Neurology Source Type: research

Calcium and magnesium in drinking water and risk of myocardial infarction and stroke —a population-based cohort study
ConclusionsDrinking water with a high concentration of calcium and magnesium, particularly magnesium, may lower the risk of stroke in postmenopausal women.
Source: American Journal of Clinical Nutrition - July 11, 2022 Category: Nutrition Source Type: research

Dietary calcium intake and risk of cardiovascular disease, stroke, and fracture in a population with low calcium intake.
Conclusion: In Korean women, increased dietary calcium intake was associated with a decreased CVD risk, but it did not influence the risk of stroke or fracture. PMID: 28615253 [PubMed - as supplied by publisher]
Source: The American Journal of Clinical Nutrition - June 14, 2017 Category: Nutrition Authors: Kong SH, Kim JH, Hong AR, Cho NH, Shin CS Tags: Am J Clin Nutr Source Type: research

Prognostic Value of Coronary CT Angiography for Predicting Poor Cardiac Outcome in Stroke Patients without Known Cardiac Disease or Chest Pain: The Assessment of Coronary Artery Disease in Stroke Patients Study.
CONCLUSION: Assessment of stenosis degree and plaque type using CCTA provided additional prognostic value over CACS and FRS to risk stratify stroke patients without prior history of CAD better. PMID: 32691541 [PubMed - in process]
Source: Korean Journal of Radiology - July 23, 2020 Category: Radiology Tags: Korean J Radiol Source Type: research

Calcium and magnesium in drinking water and risk of myocardial infarction and stroke - a population-based cohort study
CONCLUSION: Drinking water with a high concentration of calcium and magnesium, particularly magnesium, may lower the risk of stroke in postmenopausal women.PMID:35816459 | DOI:10.1093/ajcn/nqac186
Source: The American Journal of Clinical Nutrition - July 11, 2022 Category: Nutrition Authors: Emilie Helte Melle S äve-Söderbergh Susanna C Larsson Agneta Åkesson Source Type: research

Dietary calcium intake and risk of cardiovascular disease, stroke, and fracture in a population with low calcium intake Cardiovascular disease risk
Conclusion: In Korean women, increased dietary calcium intake was associated with a decreased CVD risk, but it did not influence the risk of stroke or fracture.
Source: American Journal of Clinical Nutrition - July 3, 2017 Category: Nutrition Authors: Kong, S. H., Kim, J. H., Hong, A. R., Cho, N. H., Shin, C. S. Tags: Nutritional Epidemiology Research Articles, Research Need: Role of Nutrition in Health Maintenance Cardiovascular disease risk Source Type: research

New thrombolytic strategy providing neuroprotection in experimental ischemic stroke: MMP10 alone or in combination with tissue-type plasminogen activator
ConclusionThese results show that MMP10, either alone or in combination with tPA, might represent a new strategy for thrombolysis in ischemic stroke, providing higher protection against cerebrovascular damage.
Source: Cardiovascular Research - April 3, 2017 Category: Cardiology Source Type: research

Vitamin D 3 Supplementation Reduces Subsequent Brain Injury and Inflammation Associated with Ischemic Stroke
AbstractAcute inflammation can exacerbate brain injury after ischemic stroke. Beyond its well-characterized role in calcium metabolism, it is becoming increasingly appreciated that the active form of vitamin D, 1,25-dihydroxyvitamin D3 (1,25-VitD3), has potent immunomodulatory properties. Here, we aimed to determine whether 1,25-VitD3 supplementation could reduce subsequent brain injury and associated inflammation after ischemic stroke. Male C57Bl6 mice were randomly assigned to be administered either 1,25-VitD3 (100  ng/kg/day) or vehicle i.p. for 5 day prior to stroke. Stroke was induced via middle cerebral artery occl...
Source: NeuroMolecular Medicine - February 23, 2018 Category: Neurology Source Type: research

Ischemic stroke and kynurenines: medicinal chemistry aspects.
Abstract Ischemic stroke is one of the leading causes of mortality and permanent disability in developed countries. Stroke induces massive glutamate release, which in turn causes N-Methyl-D-aspartate (NMDA) receptor over-excitation and thus calcium overload in neurons leading to cell death via apoptotic cascades. The kynurenine pathway is a complex enzymatic cascade of tryptophan catabolism, generating various neuroactive metabolites. One metabolite, kynurenic acid (KYNA), is a potent endogenous NMDA glutamate receptor antagonist, making it a possible therapeutic tool to decrease excitotoxicity and neuroinflammati...
Source: Current Medicinal Chemistry - March 12, 2018 Category: Chemistry Authors: Hertelendy P, Toldi J, Fulop F, Vecsei L Tags: Curr Med Chem Source Type: research