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Total 119 results found since Jan 2013.

Perfuze raises $3m seed round for Millipede stroke catheter
Perfuze said today that it raised more than $3 million for the Millipede catheter it’s developing to treat ischemic stroke. Although not quite in stealth mode, the Galway, Ireland-based firm is close-mouthed about its technology. CEO Wayne Allen and CTO Liam Mullins (who co-founded Embo Medical before its  in 2015,  $YY acquisition by C.R. Bard in 2015) founded Perfuze last year. The €3 million ($3.4 million) seed round, earmarked for Millipede development, was led by European VC shop Earlybird. MedFocus, Enterprise Ireland and an Irish syndicate of medtech veterans and stroke physicians also participated, Pe...
Source: Mass Device - January 29, 2019 Category: Medical Devices Authors: Brad Perriello Tags: Catheters Featured Funding Roundup Neurological Perfuze Stroke Source Type: news

Caveats to Acute Imaging for Acute Stroke in the Setting of Venoarterial Extracorporeal Membrane Oxygenation
Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly used for cardiorespiratory support in medically refractory cases. The high rate of neurologic complications, specifically cerebrovascular disorders such as acute ischemic stroke, in VA-ECMO patients frequently prompts the acquisition of neuroimaging studies such as CT with angiography and perfusion imaging. Clinicians must be familiar with the ECMO-related artifacts when interpreting such studies. Here, we describe a case of asymmetric contrast opacification in a VA-ECMO patient with axillary artery cannulation.
Source: Neurology Clinical Practice - December 13, 2021 Category: Neurology Authors: Viamonte, M. A., Yu, J., Echevarria, F. D., Nagae, L., Youn, T. S., Tahsili-Fahadan, P., Simpkins, A. N. Tags: Stroke in young adults, CT, All Cerebrovascular disease/Stroke Case Source Type: research

Sensors, Vol. 17, Pages 1283: A Novel Real-Time Path Servo Control of a Hardware-in-the-Loop for a Large-Stroke Asymmetric Rod-Less Pneumatic System under Variable Loads
This project aims to develop a novel large stroke asymmetric pneumatic servo system of a hardware-in-the-loop for path tracking control under variable loads based on the MATLAB Simulink real-time system. High pressure compressed air provided by the air compressor is utilized for the pneumatic proportional servo valve to drive the large stroke asymmetric rod-less pneumatic actuator. Due to the pressure differences between two chambers, the pneumatic actuator will operate. The highly nonlinear mathematical models of the large stroke asymmetric pneumatic system were analyzed and developed. The functional approximation techniq...
Source: Sensors - June 4, 2017 Category: Biotechnology Authors: Hao-Ting Lin Tags: Article Source Type: research

Tasked-Based Functional Brain Connectivity in Multisensory Control of Wrist Movement After Stroke
In this study we documented brain connectivity associated with multisensory integration during wrist control in healthy young adults, aged matched controls and stroke survivors. A novel functional MRI task paradigm involving wrist movement was developed to gain insight into the effects of multimodal sensory feedback on brain functional networks in stroke participants. This paradigm consisted of an intermittent position search task using the wrist during fMRI signal acquisition with visual and auditory feedback of proximity to a target position. We enrolled 12 young adults, 10 participants with chronic post-stroke hemipares...
Source: Frontiers in Neurology - June 12, 2019 Category: Neurology Source Type: research

J&J’s Biosense Webster buys Coherex Medical and its WaveCrest anti-stroke device
Johnson & Johnson (NYSE:JNJ) subsidiary Biosense Webster said today that it acquired Coherex Medical for an undisclosed amount. Salt Lake City-based Coherex makes the Wavecrest anti-stroke device, which is designed to occlude the heart’s left atrial appendage to prevent blood clots from forming that could cause stroke. “The addition of the Coherex WaveCrest system complements our comprehensive portfolio of therapeutic solutions for patients suffering from atrial fibrillation who not only suffer from reduced quality of life but also face a significantly greater risk of a stroke,” group chairman Shlomi...
Source: Mass Device - November 20, 2015 Category: Medical Equipment Authors: Brad Perriello Tags: Cardiac Implants Cardiovascular Mergers & Acquisitions BioSense Webster Inc. Coherex Medical Johnson & Johnson Source Type: news

Hyper-acute EEG alterations predict functional and morphological outcomes in thrombolysis-treated ischemic stroke: a wireless EEG study
AbstractOwing to the large inter-subject variability, early post-stroke prognosis is challenging, and objective biomarkers that can provide further prognostic information are still needed. The relation between quantitative EEG parameters in pre-thrombolysis hyper-acute phase and outcomes has still to be investigated. Hence, possible correlations between early EEG biomarkers, measured on bedside wireless EEG, and short-term/long-term functional and morphological outcomes were investigated in thrombolysis-treated strokes. EEG with a wireless device was performed in 20 patients with hyper-acute (<  4.5 h from onset) ant...
Source: Medical and Biological Engineering and Computing - December 4, 2020 Category: Biomedical Engineering Source Type: research

Sensors, Vol. 21, Pages 1806: Development of a Low-Cost, Modular Muscle –Computer Interface for At-Home Telerehabilitation for Chronic Stroke
We describe our modular electromyography acquisition, processing, and feedback algorithms to train differentiated muscle control during at-home therapist-guided sessions. Additionally, we evaluated the performance of low-cost sensors for our training task with two healthy individuals. Finally, we present the results of a case study with a stroke survivor who used the system for 40 sessions over 10 weeks of training. In line with our previous research, our results suggest that using low-cost sensors provides similar results to those using research-grade sensors for low forces during an isometric task. Our preliminary case s...
Source: Sensors - March 5, 2021 Category: Biotechnology Authors: Octavio Marin-Pardo Coralie Phanord Miranda Rennie Donnelly Christopher M. Laine Sook-Lei Liew Tags: Article Source Type: research

Telerehabilitation and emerging virtual reality approaches to stroke rehabilitation
Purpose of review: Stroke is the leading cause of permanent motor disability in the United States, and the rapidly aging population makes finding large-scale treatment solutions to this problem a national priority. Telerehabilitation is an emerging approach that is being used for the effective treatment of multiple diseases, and is beginning to show promise for stroke. The purpose of this review is to identify and highlight the areas of telerehabilitation that require the most research attention. Recent findings: Although there are many different forms of telerehabilitation approaches being attempted for stroke, the only a...
Source: Current Opinion in Neurology - November 7, 2014 Category: Neurology Tags: TRAUMA AND REHABILITATION: Edited by S. Thomas Carmichael Source Type: research

CT perfusion in acute stroke calls: A pictorial review and differential diagnoses
Summary CT perfusion is increasingly utilised in hyperacute stroke to facilitate diagnosis and patient selection for reperfusion therapies. This review article demonstrates eight examples of how CT perfusion can be used to diagnose stroke mimics and small volume infarcts, which can be easily missed on non‐contrast CT, and to suggest the presence of an ischaemic penumbra. Radiologists involved in stroke management must understand the importance of rapid imaging acquisition and be confident in the prospective interpretation of this powerful diagnostic tool as we move into a new era of hyperacute stroke care.
Source: Australasian Radiology - December 2, 2015 Category: Radiology Authors: Albert H Chiu, Timothy J Phillips, Constantine C Phatouros, Tejinder P Singh, Graeme J Hankey, David J Blacker, William McAuliffe Tags: Medical Imaging—Review Article Source Type: research

Imaging of Acute Stroke
This article reviews the current state of imaging for acute ischemic stroke. Protocolized imaging acquisition using computed tomography in conjunction with coordinated stroke care allows for rapid diagnosis and prompt revascularization. Following the initial evidence to support endovascular therapy for large-vessel occlusion, published between 2014 and 2015, there are now guidelines supporting treatment up to 24  hours after time of onset of symptoms. Neuroimaging remains a central component in diagnosing acute stroke and potentially excluding patients from stroke treatment, as outlined in this article.
Source: Radiologic Clinics of North America - October 1, 2019 Category: Radiology Authors: Steven Hetts, Rajkamal Khangura Source Type: research

A Post-Stroke Rehabilitation System Integrating Robotics, VR and High-Resolution EEG Imaging
We propose a system for the neuro-motor rehabilitation of upper limbs in stroke survivors. The system is composed of a passive robotic device (Trackhold) for kinematic tracking and gravity compensation, five dedicated virtual reality (VR) applications for training of distinct movement patterns, and high-resolution EEG for synchronous monitoring of cortical activity. In contrast to active devices, the Trackhold omits actuators for increased patient safety and acceptance levels, and for reduced complexity and costs. VR applications present all relevant information for task execution as easy-to-understand graphics that do not...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - September 1, 2013 Category: Neuroscience Source Type: research

Codman Neuro Announces Acquisition Of Neuravi Limited To Accelerate Innovation In Acute Ischemic Stroke Therapy
Second Acquisition in Months Demonstrates Commitment to Addressing Unmet Needs in Stroke IRVINE, Calif., April 10, 2017 -- (Healthcare Sales & Marketing Network) -- Codman Neuro today announced the acquisition of Neuravi Limited, a privately held Irish... Devices, Neurology, Interventional, Mergers & Acquisitions Codman, Johnson & Johnson, Neuravi Limited, EmboTrap, stroke
Source: HSMN NewsFeed - April 10, 2017 Category: Pharmaceuticals Source Type: news

A “one-stop-shop” 4D CTA protocol using 320-row CT for advanced imaging in acute ischemic stroke: a technical note
AbstractThis technical note describes a novel CT scan protocol that includes a non-enhanced CT, dynamic CTA, and perfusion of the whole brain and CTA of the carotid arteries using a 320-row area detector CT scanner, with a unique contrast injection and acceptable radiation exposure dose in patients presenting with acute ischemic stroke. The acquisition parameters and reconstruction parameters will be discussed including the use of model-based iterative reconstruction (MBIR), time summing (tMIP), and subtraction techniques to optimize the results of this protocol.Key Points• Scanning on a 320-row area detector CT can achi...
Source: European Radiology - August 5, 2019 Category: Radiology Source Type: research

Magnetic Resonance pH Imaging in Stroke – Combining the Old With the New
The study of stroke has historically made use of traditional spectroscopy techniques to provide the ground truth for parameters like pH. However, techniques like 31P spectroscopy have limitations, in particular poor temporal and spatial resolution, coupled with a need for a high field strength and specialized coils. More modern magnetic resonance spectroscopy (MRS)-based imaging techniques like chemical exchange saturation transfer (CEST) have been developed to counter some of these limitations but lack the definitive gold standard for pH that 31P spectroscopy provides. In this perspective, both the traditional (31P spectr...
Source: Frontiers in Physiology - February 3, 2022 Category: Physiology Source Type: research

Boston Scientific's Watchman stroke prevention device approved after 4 years
Boston Scientific's Watchman device, an alternative to blood thinners for stroke prevention, has earned approval in the U.S. four years after the medical device giant bought the product in its $375 million acquisition of Atritech. The Watchman Left Atrial Appendage Closure Device has been called one of "the two most meaningful pipeline products (along with the Synergy stent) expected to launch over the next few years" by Leerink Partners analyst Danielle Antalffy. Mike Mahoney, the CEO of Marlborough,…
Source: bizjournals.com Health Care:Biotechnology headlines - March 15, 2015 Category: Biotechnology Authors: Don Seiffert Source Type: news